کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9429451 1615205 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
α-Synuclein binding to rab3a in multiple system atrophy
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
α-Synuclein binding to rab3a in multiple system atrophy
چکیده انگلیسی
Abnormal α-synuclein binding to rab3a was also found in the substantia nigra but not in the cerebral cortex in Parkinson's disease. These findings suggest membrane and synaptic vesicle trafficking as vulnerable targets in MSA. Since rab3a is a member of the Ras super-family of small (21-25 kDa) GTP-binding proteins which is involved in the regulation of the internal trafficking, exocytosis and neurotransmission, and vesicle endocytosis, the present findings might suggest membrane and synaptic vesicle trafficking as vulnerable targets in MSA.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Letters - Volume 380, Issues 1–2, 20–27 May 2005, Pages 170-175
نویسندگان
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