کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9454780 | 1308556 | 2005 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The immunomodulatory effects of the dimer of lysozyme (KLP-602) in carp (Cyprinus carpio L)-in vivo study
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
شیمی زیست محیطی
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چکیده انگلیسی
The dimer of lysozyme was administered to carp (Cyprinus carpio L.) in an attempt to reduce the suppression of response in fish exposed to the cypermethrin. Experimental studies were carried out on cells isolated from blood and pronephros of carp. In the in vivo studies fish were intoxicated with cypermethrin (synthetic pesticide) at a dose of LD5. After 24Â h fish were injected intraperitoneally with a modulator-the dimer of lysozyme (KLP-602) at a dose of 0.02Â mg/kg of body weight. In the study we determined the metabolic activity of phagocyte cells and the proliferative ability of lymphocytes stimulated by ConA and LPS. The results indicate that this modulator is useful for stimulation of cellular and humoral immunity after experimentally induced suppression by selected pesticide.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ecotoxicology and Environmental Safety - Volume 61, Issue 1, May 2005, Pages 121-127
Journal: Ecotoxicology and Environmental Safety - Volume 61, Issue 1, May 2005, Pages 121-127
نویسندگان
Anna Rymuszka, Maria Studnicka, Andrzej K. Siwicki, Anna SierosÅawska, Adam Bownik,