کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
952881 927550 2011 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Translational science and the hidden research system in universities and academic hospitals: A case study
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی سیاست های بهداشت و سلامت عمومی
پیش نمایش صفحه اول مقاله
Translational science and the hidden research system in universities and academic hospitals: A case study
چکیده انگلیسی

Innovation systems (IS) and science policy scholarship predominantly focus on linkages between universities and industry, and the commercial translation of academic discoveries. Overlooked in such analyses are important connections between universities and academic hospitals, and the non-commercial aspects of translational science. The two types of institutions tend to be collapsed into a single entity—‘the university’—and relational flows are lost. Yet the distinctions and flows between the two are crucial elements of translational science and the biomedical innovation system. This paper explores what has been called the ‘hidden research system’ that connects hospitals, universities, and their resources, with the clinical and scientific actors who make the linkages possible. Then, using a novel conceptual model of translational science, we examine the individual interactions and dynamics involved in a particular example of the biomedical innovation system at work: the diagnosis of IRAK-4 deficiency, a rare immunological disorder, and the translational flows that result. Contra to conventional IS analyses, we are able to point to the strong role of public-sector institutions, and the weak role of the private-sector, in the translational processes described here. Our research was conducted within a Canadian network of scientists and clinician–scientists studying the pathogenomics of immunological disorders and innate immunity.

Research highlights
► In promoting translational science, innovation policies emphasize links between universities and industry.
► Key role of translational but non-commercial links between universities and academic hospitals often overlooked in such policies.
► A novel conceptual model illustrates the importance of this ‘hidden research system’ in biomedical innovation.
► Translational flows are explored through a case study of the diagnosis of IRAK-4, a rare immunological deficiency.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Social Science & Medicine - Volume 72, Issue 4, February 2011, Pages 537–544
نویسندگان
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