Drazepinone, a trisubstituted tetrahydronaphthofuroazepinone with herbicidal activity produced by Drechslera siccans

We report on the isolation and the chemical and biological characterization of drazepinone (1), a 3,5,12a-trimethyl-2,5,5a,12a-tetrahydro-1H-naphtho[2′,3′:4,5]furo[2,3-b]azepin-2-one produced by Drechslera siccans, showing interesting selective herbicidal properties, not associated to antibacterial and antifungal activities.