Cyclolignans from Scyphocephalium ochocoa via high-throughput natural product chemistry methods

Two 2,7′-cyclolignans, ocholignans A and B, were obtained as mass-limited samples from Scyphocephalium ochocoa via high-throughput natural product chemistry methods. The rapid structure elucidation of each compound was primarily facilitated by NMR data acquisition using a capillary-scale NMR probe. Ocholignan A was found to possess significant in vitro antibacterial activity.