New biologically active linear triterpenes from the bark of three new-caledonian Cupaniopsis species

Ten new linear triterpenes named cupaniopsins A-E and analogues (1-10) have been isolated from the bark of three neocaledonian Cupaniopsis species (Sapindaceae). The structures were elucidated by extensive mono- and bi-dimensional spectroscopy and mass spectrometry. Five compounds exhibited potent binding affinity for peroxisome proliferator-activated receptor (PPAR-γ).