New glycolipid inhibitors of Myt1 kinase

Bioassay-directed fractionation of a marine algal species using a bioassay for inhibitors of the enzyme Myt1 kinase yielded the novel glycoglycerolipids 1 and 2 as the major bioactive constituents. The structures of 1 and 2 were assigned by NMR spectra together with chemical and enzymatic degradations and by analyses of mass spectroscopic data.