Chemoselective and convenient preparation of 1,1-diacetates from aldehydes, mediated by solid lithium perchlorate under solvent-free conditions

A simple, efficient, and general method has been developed for the conversion of aldehydes to 1,1-diacetates with the use of acetic anhydride and solid LiClO4 under first solvent-free and mild conditions in good yields. This method applies to not only simple but also to conjugated aldehydes.