Sulfamide-amine alcohol catalyzed enantioselective alkynylation of aromatic ketones

Readily available sulfamide-amine alcohol 11 was found to be effective in catalyzing the enantioselective phenylacetylene addition to aromatic ketones without using another central metal, providing the chiral tertiary propargylic alcohols in good yields (up to 83%) and enantioselectivities (up to 83% e.e.).