Highly efficient palladium-catalyzed Suzuki-Miyaura cross-coupling of aryl bromides using 2-(diphenylphosphino) benzaldoxime ligand

A highly effective method for palladium-catalyzed Suzuki-Miyaura coupling of aryl bromides and arylboronic acids using novel 2-(diphenylphosphino) benzaldoxime ligand was developed. The new catalytic system based on Pd(OAc)2 and the readily prepared and air stable ligand afforded high turnover numbers (up to 104) for a variety of substrates.