Highly diastereoselective epoxidation of protected α-amino alkenes catalyzed by ruthenium porphyrin/Cl2PyNO system

Protected α-amino epoxides were successfully obtained in high threo-selectivity (up to 99%) under mild reaction conditions by using carbonyl 5,10,15,20-tetra(2,6-dichlorophenyl)porphyrin ruthenium(II) [Ru(TDCPP)CO] as catalyst and 2,6-dichloropyridine N-oxide (Cl2PyNO) as oxidant.