A chiral disulfide derived from (R)-cysteine in the enantioselective addition of diethylzinc to aldehydes: loading effect and asymmetric amplification

A chiral disulfide is described to catalyze the enantioselective addition of diethylzinc to benzaldehyde with high enantioselectivities. Nonlinear effects have also been evaluated and it has been found to be strictly linear.