کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9753193 | 1494197 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Solid phase microextraction for analysis of alkanes and aromatic hydrocarbons in human breath
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
In this work, solid phase microextraction-gas chromatograph (SPME-GC) was applied to analyze alkanes and aromatic hydrocarbons in human breath, providing a potential non-invasive method to screen lung cancer. This method has been optimized and evaluated. It provided quantification limits ranging from 0.04 to 4.2Â ng/mL, linear correlations ranging from 0.9845 to 0.9966 and R.S.D. values less than 9.8%. Total 30 breath samples, from 15 lung cancer patients and 15 healthy persons, were analyzed, and the alkanes and aromatic hydrocarbons were detected in 73.3% lung cancer patients and in 13.3% healthy persons by this method. Above all, It was demonstrated that this SPME-GC method provided a sensitive and non-invasive measure means to analyze alkanes and aromatic hydrocarbons in human breath, and brought forward a potential application for screening lung cancer.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography B - Volume 826, Issues 1â2, 5 November 2005, Pages 69-74
Journal: Journal of Chromatography B - Volume 826, Issues 1â2, 5 November 2005, Pages 69-74
نویسندگان
Hao Yu, Liang Xu, Ping Wang,