Thermodynamics and cancer stationary states

• Cancer is an open complex dynamic and self-organizing system.
• Irreversibility is the fundamental quantity for the analysis of the open systems.
• The entropy generation describes the irreversibility of the open systems.
• Entropy generation is introduced in the cancer analysis.

Cancer can be described as an open complex dynamic and self-organizing system. The stationary states of the open systems are analysed in engineering thermodynamics by entropy generation. The recent results on entropy generation are suggested as the basis of a new approach to cancer analysis in order to study the cancer evolution and new possible anticancer therapies.