کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9882342 1536554 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Asymmetric binding of membrane proteins to GroEL
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Asymmetric binding of membrane proteins to GroEL
چکیده انگلیسی
The interaction of GroEL with non-native soluble proteins has been studied intensively and structure-function relationships have been established in considerable detail. Recently, we found that GroEL is also able to bind membrane proteins in the absence of detergents and deliver them to liposomes in a biologically active state. Here, we report that three well-studied membrane proteins (bacteriorhodopsin, LacY, and the bacteriophage λ holin) bind asymmetrically to tetradecameric GroEL. Each of the membrane proteins was visualized in one of the center cavities of GroEL using single particle analysis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Archives of Biochemistry and Biophysics - Volume 434, Issue 2, 15 February 2005, Pages 352-357
نویسندگان
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