کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9917689 1556308 2005 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Chitosan-reinforced alginate microspheres obtained through the emulsification/internal gelation technique
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی اکتشاف دارویی
پیش نمایش صفحه اول مقاله
Chitosan-reinforced alginate microspheres obtained through the emulsification/internal gelation technique
چکیده انگلیسی
Hb release from microspheres showed a pH-dependent profile and was affected by chitosan coating. Under simulated gastric conditions, a total Hb burst release from uncoated microspheres was decreased with one-stage and two-stage chitosan coatings (68% and 28%, respectively). At pH 6.8, the Hb release from coated microspheres was fast but incomplete. These results suggest an optimization of the coating method to protect Hb under acidic conditions and to permit a complete but sustained release of Hb.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Pharmaceutical Sciences - Volume 25, Issue 1, May 2005, Pages 31-40
نویسندگان
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