کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9952307 1445215 2018 24 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
BE-DTI': Ensemble framework for drug target interaction prediction using dimensionality reduction and active learning
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر علوم کامپیوتر (عمومی)
پیش نمایش صفحه اول مقاله
BE-DTI': Ensemble framework for drug target interaction prediction using dimensionality reduction and active learning
چکیده انگلیسی
Missing interactions and new interactions are predicted using the proposed framework. Some of the known interactions are removed from the original dataset and their interactions are recalculated to check the accuracy of the proposed framework. Moreover, validation of the proposed approach is performed using the external dataset. All these results show that structurally similar drugs tend to interact with similar targets.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computer Methods and Programs in Biomedicine - Volume 165, October 2018, Pages 151-162
نویسندگان
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