Synthesis and antimycobacterial evaluation of new trans-cinnamic acid hydrazide derivatives Fulltext Access 4 Pages 2008
A novel bicyclic hexapeptide, RA-XVIII, from Rubia cordifolia: Structure, semi-synthesis, and cytotoxicity Fulltext Access 4 Pages 2008
A very simple synthesis of GlcNAc-α-pyrophosphoryl-decanol: A substrate for the assay of a bacterial galactosyltransferase Fulltext Access 4 Pages 2008
Ohioensins F and G: Protein tyrosine phosphatase 1B inhibitory benzonaphthoxanthenones from the Antarctic moss Polytrichastrum alpinum Fulltext Access 4 Pages 2008
Calcitonin gene-related peptide (CGRP) receptor antagonists: Investigations of a pyridinone template Fulltext Access 4 Pages 2008
Glycopolydiacetylene nanoparticles as a chromatic biosensor to detect Shiga-like toxin producing Escherichia coli O157:H7 Fulltext Access 4 Pages 2008
Modifying the glycosidic linkage in digitoxin analogs provides selective cytotoxins Fulltext Access 4 Pages 2008
Preparation of C60-based active esters and coupling of C60 moiety to amines or alcohols Fulltext Access 4 Pages 2008
Novel heterocycle-substituted pyrimidines as inhibitors of NF-κB transcription regulation related to TNF-α cytokine release Fulltext Access 4 Pages 2008
1-(2-Phenoxyphenyl)methanamines: SAR for dual serotonin/noradrenaline reuptake inhibition, metabolic stability and hERG affinity Fulltext Access 4 Pages 2008
Binding free energy calculation for duocarmycin/DNA complex based on the QPLD-derived partial charge model Fulltext Access 4 Pages 2008
Synthesis and evaluation of a γ-lactam as a highly selective EP2 and EP4 receptor agonist Fulltext Access 4 Pages 2008
Antiproliferative effects of dibenzocyclooctadiene lignans isolated from Schisandra chinensis in human cancer cells Fulltext Access 4 Pages 2008
2-Oxo-tetrahydro-1,8-naphthyridines as selective inhibitors of malarial protein farnesyltransferase and as anti-malarials Fulltext Access 4 Pages 2008
Anti-Pneumocystis carinii and antiplasmodial activities of primaquine-derived imidazolidin-4-ones Fulltext Access 4 Pages 2008
Conformationally constrained diketopimelic acid analogues as inhibitors of dihydrodipicolinate synthase Fulltext Access 4 Pages 2008
Selective cell adhesion inhibitors: Barbituric acid based α4β7—MAdCAM inhibitors Fulltext Access 4 Pages 2008
Synthesis and biological activity of simplified denoviose-coumarins related to novobiocin as potent inhibitors of heat-shock protein 90 (hsp90) Fulltext Access 4 Pages 2008
1-Aryl-tetrahydroisoquinoline analogs as active anti-HIV agents in vitro Fulltext Access 4 Pages 2008
Structure–activity relationship of ortho- and meta-phenol based LFA-1 ICAM inhibitors Fulltext Access 4 Pages 2008
Synthesis of N-acridinyl-Nâ²-alkylguanidines: Dramatic influence of amine to guanidine replacement on the physicochemical properties Fulltext Access 4 Pages 2008
Aglycone exploration of C-arylglucoside inhibitors of renal sodium-dependent glucose transporter SGLT2 Fulltext Access 4 Pages 2008
Structure–activity relationships of compounds targeting mycobacterium tuberculosis 1-deoxy-d-xylulose 5-phosphate synthase Fulltext Access 4 Pages 2008
Initial SAR studies on apamin-displacing 2-aminothiazole blockers of calcium-activated small conductance potassium channels Fulltext Access 4 Pages 2008
Synthesis of 5-(1-H or 1-alkyl-5-oxopyrrolidin-3-yl)-8-hydroxy-[1,6]-naphthyridine-7-carboxamide inhibitors of HIV-1 integrase Fulltext Access 4 Pages 2008
Designing rapid onset selective serotonin re-uptake inhibitors. Part 3: Site-directed metabolism as a strategy to avoid active circulating metabolites: Structure–activity relationships of (thioalkyl)phenoxy benzylamines Fulltext Access 4 Pages 2008
Methoxy-substituted 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives exhibit differential binding affinities at the 5-HT2A receptor Fulltext Access 4 Pages 2008
Optimization of small molecule agonists of the thrombopoietin (Tpo) receptor derived from a benzo[a]carbazole hit scaffold Fulltext Access 4 Pages 2008
Discovery and biological evaluation of benzo[a]carbazole-based small molecule agonists of the thrombopoietin (Tpo) receptor Fulltext Access 4 Pages 2008
Dual DAT/σ1 receptor ligands based on 3-(4-(3-(bis(4-fluorophenyl)amino)propyl)piperazin-1-yl)-1-phenylpropan-1-ol Fulltext Access 4 Pages 2008
Tacrine based human cholinesterase inhibitors: Synthesis of peptidic-tethered derivatives and their effect on potency and selectivity Fulltext Access 4 Pages 2008
Discovery and optimization of substituted piperidines as potent, selective, CNS-penetrant α4β2 nicotinic acetylcholine receptor potentiators Fulltext Access 4 Pages 2008
Design, synthesis and characterization of podocarpate derivatives as openers of BK channels Fulltext Access 4 Pages 2008
New functionalized 1,2,4-trioxepanes: Synthesis and antimalarial activity against multi-drug resistant P. yoelii in mice Fulltext Access 4 Pages 2008
Design and synthesis of 2-amino-isoxazolopyridines as Polo-like kinase inhibitors Fulltext Access 4 Pages 2008
Design, synthesis and antiproliferative activity of two new heteroannelated (−)-muricatacin mimics Fulltext Access 4 Pages 2008
Synthesis and antiproliferative activity of unnatural enantiomers of 7-epi-goniofufurone and crassalactone C Fulltext Access 4 Pages 2008
Molecular design to enhance the penetration into the retina via ocular instillation Fulltext Access 4 Pages 2008
Synthesis and evaluation of novel chromogenic peptidase substrates based on 9-(4′-aminophenyl)-10-methylacridinium salts as diagnostic tools in clinical bacteriology Fulltext Access 4 Pages 2008
Measurement of residual solvents in a drug substance by a purge-and-trap method Fulltext Access 4 Pages 2008
Simultaneous determination of six active components in crude and processed Fructus Corni by high performance liquid chromatography Fulltext Access 4 Pages 2008
Detection limit of measurement of pharmaceuticals labeled with short-lived isotopes in HPLC with flow-through γ-counter Fulltext Access 4 Pages 2008
Development and validation of a reversed-phase HPLC method for simultaneous estimation of ambroxol hydrochloride and azithromycin in tablet dosage form Fulltext Access 4 Pages 2008
Simultaneous determination of jujuboside A, B and betulinic acid in semen Ziziphi spinosae by high performance liquid chromatography-evaporative light scattering detection Fulltext Access 4 Pages 2008
Observation of interactions of human serum components with transferrin by affinity capillary electrophoresis Fulltext Access 4 Pages 2008
High-performance thin layer chromatography method for estimation of conessine in herbal extract and pharmaceutical dosage formulations Fulltext Access 4 Pages 2008
Stereospecific high-performance liquid chromatographic validation of homoeriodictyol in serum and Yerba Santa (Eriodictyon glutinosum) Fulltext Access 4 Pages 2008
Reversal of elution order for profen acid enantiomers in normal phase LC on Chiralpak AD Fulltext Access 4 Pages 2008
Separation and determination of ketoprofen, methylparaben and propylparaben in pharmaceutical preparation by micellar electrokinetic chromatography Fulltext Access 4 Pages 2008
Analysis of naphthoquinone derivatives in the Asian medicinal plant Eleutherine americana by RP-HPLC and LC–MS Fulltext Access 4 Pages 2008
Validation of a quantitative NMR method for suspected counterfeit products exemplified on determination of benzethonium chloride in grapefruit seed extracts Fulltext Access 4 Pages 2008
Determination of cephalosporins in solid binary mixtures by polarized IR- and Raman spectroscopy Fulltext Access 4 Pages 2008
Stability and in vitro release profile of enalapril maleate from different commercially available tablets: Possible therapeutic implications Fulltext Access 4 Pages 2008
Investigating noncovalent interactions of rutin – serum albumin by capillary electrophoresis – frontal analysis Fulltext Access 4 Pages 2008
Counterfeit homeopathic medicinal products: Syrups: A simple and rapid LC–ESI-MS method to detect preservatives not declared in label Fulltext Access 4 Pages 2008
Determination of paracetamol and its main impurity 4-aminophenol in analgesic preparations by micellar electrokinetic chromatography Fulltext Access 4 Pages 2008
Quality of potent Mn porphyrin-based SOD mimics and peroxynitrite scavengers for pre-clinical mechanistic/therapeutic purposes Fulltext Access 4 Pages 2008
Metrologic approaches to setting acceptance criteria: Unacceptable and unusual characteristics Fulltext Access 4 Pages 2008
Water-soluble loratadine inclusion complex: Analytical control of the preparation by microwave irradiation Fulltext Access 4 Pages 2008
Detecting counterfeit antimalarial tablets by near-infrared spectroscopy Fulltext Access 4 Pages 2008
Determination and pharmacokinetics of ascaridole in rat plasma by gas chromatography–mass spectrometry Fulltext Access 4 Pages 2008
SPE-HPTLC of procyanidins from the barks of different species and clones of Salix Fulltext Access 4 Pages 2008
Simultaneous determination of artemether and lumefantrine in fixed dose combination tablets by HPLC with UV detection Fulltext Access 4 Pages 2008
Deconstructing cytisine: The syntheses of (±)-cyfusine and (±)-cyclopropylcyfusine, fused ring analogs of cytisine Fulltext Access 4 Pages 2008
Synthesis and anti-protozoal activity of C2-substituted polyazamacrocycles Fulltext Access 4 Pages 2008
Targeting gastrin-releasing peptide receptors of prostate cancer cells for photodynamic therapy with a phthalocyanine–bombesin conjugate Fulltext Access 4 Pages 2008
Synthesis and study of antiviral and anti-radical properties of aminophenol derivatives Fulltext Access 4 Pages 2008
Aryl-indolyl maleimides as inhibitors of CaMKIIδ. Part 2: SAR of the amine tether Fulltext Access 4 Pages 2008
Synthesis of novel analogues of (+)-varitriol via olefin cross-metathesis reaction Fulltext Access 4 Pages 2008
Synthesis of novel spiropyrrolizidines as potent antimicrobial agents for human and plant pathogens Fulltext Access 4 Pages 2008
Synthesis and antibacterial activity of littorachalcone and related diphenyl ethers Fulltext Access 4 Pages 2008
Increasing permeability of phospholipid bilayer membranes to alanine with synthetic α-aminophosphonate carriers Fulltext Access 4 Pages 2008
Study of ocular pharmacokinetics of in situ gel system for S(−)-satropane evaluated by microdialysis Fulltext Access 4 Pages 2008
Perylene-conjugated pyrrole polyamide as a sequence-specific fluorescent probe Fulltext Access 4 Pages 2008
Structure elucidation of a novel synthetic thiono analogue of sildenafil detected in an alleged herbal aphrodisiac Fulltext Access 4 Pages 2008
Evaluation of hydrate formation of a pharmaceutical solid by using diffuse reflectance infrared Fourier-transform spectroscopy Fulltext Access 4 Pages 2008
HPLC method for the quantitative determination of sarcophine, a source of cembranoids with cancer chemopreventive activity Fulltext Access 4 Pages 2008
Development and validation of GC–MS method for the determination of methyl methanesulfonate and ethyl methanesulfonate in imatinib mesylate Fulltext Access 4 Pages 2008
Simultaneous determination of metoprolol succinate and amlodipine besylate in pharmaceutical dosage form by HPLC Fulltext Access 4 Pages 2008
Development and validation of RP-HPLC method for the determination of genotoxic alkyl benzenesulfonates in amlodipine besylate Fulltext Access 4 Pages 2008
Comparison of HPLC, UV spectrophotometry and potentiometric titration methods for the determination of lumefantrine in pharmaceutical products Fulltext Access 4 Pages 2008