A novel insulin-sodium oleate complex for oral administration: preparation, characterization and in vivo evaluation Fulltext Access 5 Pages 2008
Inhibiting enoyl-ACP reductase (FabI) across pathogenic microorganisms by linear sesquiterpene lactones from Anthemis auriculata Fulltext Access 5 Pages 2008
Influence of Operating Temperature and Pressure on the Polymorphic Transition of Salmeterol Xinafoate in Supercritical Fluids Fulltext Access 5 Pages 2008
Calibration of the Andersen Cascade Impactor for the Characterization of Nasal Products Fulltext Access 5 Pages 2008
Clavulanic Acid Decomposition Is Catalyzed by the Compound Itself and by Its Decomposition Products Fulltext Access 5 Pages 2008
Oral and IV Dosing: A Method to Determine the Compartment of Drug Elimination for Two-Compartment Models Fulltext Access 5 Pages 2008
Dynamic control of nanofluidic channels in protein drug delivery vehicles Fulltext Access 5 Pages 2008
Enzymatically attenuated in situ release of silver ions to combat bacterial biofilms: a feasibility study Fulltext Access 5 Pages 2008
Preparation of CyA-loaded solid lipid nanoparticles and application on ocular preparations Fulltext Access 5 Pages 2008
A new type of double-layered osmotic pump controlled release tablets of bezafibrate with poor water solubility and large dosage Fulltext Access 5 Pages 2008
Characteristics and pharmacokinetics of docetaxel liposome containing Tween 80 or PEG-DSPE Fulltext Access 5 Pages 2008
Antimalarial, antimycobacterial and cytotoxic limonoids from Chisocheton siamensis Fulltext Access 5 Pages 2008
In vivo evaluation of nitrofurantoin floating solid drug delivery system Fulltext Access 5 Pages 2008
Liposomes for (trans)dermal delivery of tretinoin: influence of drug concentration and vesicle composition Fulltext Access 5 Pages 2008
Cyclodextrin gene vectors: cell trafficking and the influence of lipophilic chain length Fulltext Access 5 Pages 2008
Sensitivity of hydrocortisone to gamma radiation in topical preparations Fulltext Access 5 Pages 2008
Synthesis of a new mPEG-dexamethasone conjugate and preliminary bioavailability studies in rabbits Fulltext Access 5 Pages 2008
Effect of moist heat sterilisation on the pyrogenicity of cell wall components from Staphylococcus aureus Fulltext Access 5 Pages 2008
Synthesis and anti-inflammatory activities of mono-carbonyl analogues of curcumin Fulltext Access 5 Pages 2008
New insight for fluoroquinophenoxazine derivatives as possibly new potent topoisomerase I inhibitor Fulltext Access 5 Pages 2008
Lobeline, a piperidine alkaloid from Lobelia can reverse P-gp dependent multidrug resistance in tumor cells Fulltext Access 5 Pages 2008
A pragmatic approach ensuring accuracy in language translation in tuberculosis research Fulltext Access 5 Pages 2008
Increased bioavailability of a transdermal application of a nano-sized emulsion preparation Fulltext Access 5 Pages 2008
Transport of sennosides and sennidines from Cassia angustifolia and Cassia senna across Caco-2 monolayers – an in vitro model for intestinal absorption Fulltext Access 5 Pages 2008
Hepatoprotective effect of Bacoside-A, a major constituent of Bacopa monniera Linn Fulltext Access 5 Pages 2008
Centella asiatica water extract inhibits iPLA2 and cPLA2 activities in rat cerebellum Fulltext Access 5 Pages 2008
In vitro cytogenetic effects of Andrographis paniculata (kalmegh) on arsenic Fulltext Access 5 Pages 2008
Antimutagenicity of hops (Humulus lupulus L.): bioassay-directed fractionation and isolation of xanthohumol Fulltext Access 5 Pages 2008
Antinoceptive effect of triterpenoid α,β-amyrin in rats on orofacial pain induced by formalin and capsaicin Fulltext Access 5 Pages 2008
Wound healing activity and docking of glycogen-synthase-kinase-3-β-protein with isolated triterpenoid lupeol in rats Fulltext Access 5 Pages 2008
4-(Heteroarylaminomethyl)-N-(2-aminophenyl)-benzamides and their analogs as a novel class of histone deacetylase inhibitors Fulltext Access 5 Pages 2008
Berberine prevents UV-induced MMP-1 and reduction of type I procollagen expression in human dermal fibroblasts Fulltext Access 5 Pages 2008
Antiproliferative activity of Pterodon pubescens Benth. seed oil and its active principle on human melanoma cells Fulltext Access 5 Pages 2008
The effect of saffron, Crocus sativus stigma, extract and its constituents, safranal and crocin on sexual behaviors in normal male rats Fulltext Access 5 Pages 2008
Apoptotic effect of hesperidin through caspase3 activation in human colon cancer cells, SNU-C4 Fulltext Access 5 Pages 2008
Hypoglycemic effects of a sesquiterpene glycoside isolated from leaves of loquat (Eriobotrya japonica (Thunb.) Lindl.) Fulltext Access 5 Pages 2008
Phytochemical analysis and in vitro evaluation of the biological activity against herpes simplex virus type 1 (HSV-1) of Cedrus libani A. Rich. Fulltext Access 5 Pages 2008
Antinociceptive effect of Russelia equisetiformis leave extracts: Identification of its active constituents Fulltext Access 5 Pages 2008
Antitumor activity of C-21 steroidal glycosides from Cynanchum auriculatum Royle ex Wight Fulltext Access 5 Pages 2008
Preventive effect of Ganoderma amboinense on acetaminophen-induced acute liver injury Fulltext Access 5 Pages 2008
Effects of the active constituents of Crocus sativus L., crocins, in an animal model of anxiety Fulltext Access 5 Pages 2008
Discovery of novel, potent and bioavailable proline-urea based macrocyclic HCV NS3/4A protease inhibitors Fulltext Access 5 Pages 2008
Synthesis and biological activity of anticoccidial agents: 5,6-Diarylimidazo[2,1-b][1,3]thiazoles Fulltext Access 5 Pages 2008
On the isolation and evaluation of a novel unsubstituted 5-nitroimidazole derivative as an agent to target tumor hypoxia Fulltext Access 5 Pages 2008
NaCl improves siRNA delivery mediated by nanoparticles of hydroxyethylated cationic cholesterol with amido-linker Fulltext Access 5 Pages 2008
N-(3-Triethoxysilylpropyl)-4-(isothiocyanatomethyl)-cyclohexane-1-carboxamide (TPICC): A heterobifunctional reagent for immobilization of biomolecules on glass surface Fulltext Access 5 Pages 2008
Novel BK channel openers containing dehydroabietic acid skeleton: Structure–activity relationship for peripheral substituents on ring C Fulltext Access 5 Pages 2008
Exploration of a fundamental substituent effect of α-ketoheterocycle enzyme inhibitors: Potent and selective inhibitors of fatty acid amide hydrolase Fulltext Access 5 Pages 2008
Bacterial translation inhibitors, 1-acylindazol-3-ols as anthranilic acid mimics Fulltext Access 5 Pages 2008
Total synthesis and biological evaluation of potent analogues of dictyostatin: Modification of the C2–C6 dienoate region Fulltext Access 5 Pages 2008
Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK) Fulltext Access 5 Pages 2008
Tetrahydro-4-quinolinamines identified as novel P2Y1 receptor antagonists Fulltext Access 5 Pages 2008
Carbonic anhydrase activators: Activation of the archaeal β-class (Cab) and γ-class (Cam) carbonic anhydrases with amino acids and amines Fulltext Access 5 Pages 2008
Overcoming hERG issues for brain-penetrating cathepsin S inhibitors: 2-Cyanopyrimidines. Part 2 Fulltext Access 5 Pages 2008
A bulge binding agent with novel wedge-shape topology for stimulation of DNA triplet repeat strand slippage synthesis Fulltext Access 5 Pages 2008
Design at the atomic level: Generation of novel hybrid biaryloxazolidinones as promising new antibiotics Fulltext Access 5 Pages 2008
Comparisons of the influenza virus A M2 channel binding affinities, anti-influenza virus potencies and NMDA antagonistic activities of 2-alkyl-2-aminoadamantanes and analogues Fulltext Access 5 Pages 2008
Synthesis and structure–activity relationships of selective norepinephrine reuptake inhibitors (sNRI) with improved pharmaceutical characteristics Fulltext Access 5 Pages 2008
Pyrrolo-pyrimidones: A novel class of MK2 inhibitors with potent cellular activity Fulltext Access 5 Pages 2008
Cathepsin B inhibitory activities of three new phthalate derivatives isolated from seahorse, Hippocampus Kuda Bleeler Fulltext Access 5 Pages 2008
Non-nucleoside inhibitors of the hepatitis C virus NS5B RNA-dependant RNA polymerase: 2-Aryl-3-heteroaryl-1,3-thiazolidin-4-one derivatives Fulltext Access 5 Pages 2008
Quantitative structure–activity relationship of phenoxyphenyl-methanamine compounds with 5HT2A, SERT, and hERG activities Fulltext Access 5 Pages 2008
2-Trifluoroacetylthiophene oxadiazoles as potent and selective class II human histone deacetylase inhibitors Fulltext Access 5 Pages 2008
Studies of the metabolic stability in cells of 5-(trifluoroacetyl)thiophene-2-carboxamides and identification of more stable class II histone deacetylase (HDAC) inhibitors Fulltext Access 5 Pages 2008
Novel 3,3-disubstituted pyrrolidines as selective triple serotonin/norepinephrine/dopamine reuptake inhibitors Fulltext Access 5 Pages 2008
Electrospray ionization mass spectroscopic analysis of peptides modified with N-ethylmaleimide or iodoacetanilide Fulltext Access 5 Pages 2008
A new family of H3 receptor antagonists based on the natural product Conessine Fulltext Access 5 Pages 2008
Implications for selectivity of 3,4-diarylquinolinones as p38αMAP kinase inhibitors Fulltext Access 5 Pages 2008
Selective, high affinity A2B adenosine receptor antagonists: N-1 monosubstituted 8-(pyrazol-4-yl)xanthines Fulltext Access 5 Pages 2008
Novel three-component synthesis and antiproliferative properties of diversely functionalized pyrrolines Fulltext Access 5 Pages 2008
Synthesis, SAR, and Evaluation of 4-[2,4-Difluoro-5-(cyclopropylcarbamoyl)phenylamino]pyrrolo[2,1-f][1,2,4]triazine-based VEGFR-2 kinase inhibitors Fulltext Access 5 Pages 2008
Synthesis and SAR of pyridazinone-substituted phenylalanine amide α4 integrin antagonists Fulltext Access 5 Pages 2008
Synthesis and structure–activity relationships of heteroaryl substituted-3,4-diamino-3-cyclobut-3-ene-1,2-dione CXCR2/CXCR1 receptor antagonists Fulltext Access 5 Pages 2008
α,β-Cyclic-β-benzamido hydroxamic acids: Novel oxaspiro[4.4]nonane templates for the discovery of potent, selective, orally bioavailable inhibitors of tumor necrosis factor-α converting enzyme (TACE) Fulltext Access 5 Pages 2008
2,6-Diaryl-4-phenacylaminopyrimidines as potent and selective adenosine A2A antagonists with reduced hERG liability Fulltext Access 5 Pages 2008
Synthesis and evaluation of [123I] labeled iodovinyl amino acids syn-, anti-1-amino-3-[2-iodoethenyl]-cyclobutane-1-carboxylic acid, and 1-amino-3-iodomethylene-cyclobutane-1-carboxylic acid as potential SPECT brain tumor imaging agents Fulltext Access 5 Pages 2008
Development of novel 2-[4-(aminoalkoxy)phenyl]-4(3H)-quinazolinone derivatives as potent and selective histamine H3 receptor inverse agonists Fulltext Access 5 Pages 2008
Discovery of 1,3-disubstituted-1H-pyrrole derivatives as potent Melanin-Concentrating Hormone Receptor 1 (MCH-R1) antagonists Fulltext Access 5 Pages 2008
Evaluation of indazole-based compounds as a new class of potent KDR/VEGFR-2 inhibitors Fulltext Access 5 Pages 2008
2-Substituted piperazine-derived imidazole carboxamides as potent and selective CCK1R agonists for the treatment of obesity Fulltext Access 5 Pages 2008
Synthesis and application of a new 2′,3′-isopropylidene guanosine substituted cap analog Fulltext Access 5 Pages 2008
Synthesis and evaluation of indolinyl- and indolylphenylacetylenes as PET imaging agents for β-amyloid plaques Fulltext Access 5 Pages 2008
An osteoclast-targeting agent for imaging and therapy of bone metastasis Fulltext Access 5 Pages 2008
Synthesis of a C-glucosylated cyclopropylamide and evaluation as a glycogen phosphorylase inhibitor Fulltext Access 5 Pages 2008
Modification of the side chain of micromolide, an anti-tuberculosis natural product Fulltext Access 5 Pages 2008
Synthesis and in vitro evaluation of imidazopyridazines as novel inhibitors of the malarial kinase PfPK7 Fulltext Access 5 Pages 2008