دانلود مقالات ISI درباره 3-Ma + ترجمه فارسی

ERK1/2/mTOR/Stat3 pathway-mediated autophagy alleviates traumatic brain injury-induced acute lung injury

Keywords: ERK1/2; extracellular signal-regulated kinase 1/2; mTOR; mechanistic target of rapamycin; Stat3; signal transducer and activator of transcription 3; TBI; traumatic brain injury; ALI; acute lung injury; HMGB1; high-mobility group box protein 1; 3-MA; 3‑m

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Canagliflozin exerts anti-inflammatory effects by inhibiting intracellular glucose metabolism and promoting autophagy in immune cells

Keywords: AMPK; AMP-activated protein kinase; pAMPK; phosphor-AMPK; CAN; canagliflozin; 2-DG; 2-deoxy-d-glucose; ECAR; extracellular acidification rate; ELISA; enzyme linked immunosorbent assay; IL-1; interleukin-1; IL-6; interleukin-6; LC3; microtubule-associated

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Modulating autophagy in cancer therapy: Advancements and challenges for cancer cell death sensitization

Keywords: 3-MA; 3-Methyl Adenine; Akt; Protein kinase B; AMP; Adenosine monophosphate; AMPK; AMP-activated protein kinase; Atg; Autophagy related genes; ATP; Adenosine triphosphate; Bak; Bcl-2 homologous antagonist/killer; Bax; Bcl-2-associated X protein; BCL-2; B-

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

Autophagy in ischemic stroke

Keywords: 3-MA; 3-methyladenine; Aβ; amyloid β; AIF; apoptosis-inducing factor; Akt; protein kinase B; AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; Atg; autophagy-related genes; ATP; adenosine 5′-triphosphate; BBB; blood-brain ba

دانلود رایگان متن کامل مقاله ISI 78 صفحه سال انتشار : 2018 سفارش ترجمه

Autophagy as a pharmacological target in hematopoiesis and hematological disorders

Keywords: 3-MA; 3-methyladenine; ALL; acute lymphoblastic leukemia; AMKL; acute megakaryoblastic leukemia; AML; acute myeloid leukemia; AMPK; 5′-adenosine monophosphate-activated protein kinase; APL; acute promyelocytic leukemia; Atg; autophagy-related proteins;

دانلود رایگان متن کامل مقاله ISI 80 صفحه سال انتشار : 2018 سفارش ترجمه

Autophagy in hemorrhagic stroke: Mechanisms and clinical implications

Keywords: AIM2; absent in melanoma 2; AMPK; Adenosine 5′ monophosphate-activated protein kinase; ASC; apoptosis-associated speck-like protein containing a CARD; BBB; blood-brain barrier; BH3; Bcl-2 homology 3; BMVECs; brain microvascular endothelial cells; BNIP3;

دانلود رایگان متن کامل مقاله ISI 104 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibition of autophagy aggravated 4-nitrophenol-induced oxidative stress and apoptosis in NHPrE1 human normal prostate epithelial progenitor cells

Keywords: 4-Nitrophenol; NHPrE1; Oxidative stress; Apoptosis; Autophagy; mTOR; PNP; 4-nitrophenol; DMEM; Dulbecco's modified Eagles medium; FBS; fetal bovine serum; ITS; insulin-transferrin-selenium-X; BPE; bovine pituitary extract; EGF; epidermal growth factor; 3-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Nitric oxide-regulated proteolysis of human CYP2B6 via the ubiquitin-proteasome system

Keywords: AAF; L-alanyl-N-[(1S)−3-chloro-2-oxo-1-(phenylmethyl)propyl]-L-alaninamide, mono trifluoro-acetate; ALLN; N-acetyl-L-leucyl-N-[(1S)−1-formylpentyl]-L-leucinamide; Cal III; N-[(1S)−1-[[(1-formyl-2-phenylethyl)amino]carbonyl]−2-methylpropyl]-carbami

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Angiotensin II induces calcium-mediated autophagy in podocytes through enhancing reactive oxygen species levels

Keywords: Ang II; Podocytes; TRPC6; Autophagy; ROS; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; 3-MA; 3-methyladenine; Ang II; Angiotensin II; MDA; malondialdehyde; N-MPG; N-(mercaptopropionyl)-glycine; ROS; reactive oxygen species; TRPC6; tr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Content decline of SERCA inhibitors saikosaponin a and d attenuates cardiotoxicity and hepatotoxicity of vinegar-baked Radix bupleuri

Keywords: 3-MA; 3-methyl adenine; LC3; microtubule-associated protein light chain 3; Cmax; maximum plasma concentration; GFP; green fluorescent protein; SERCA; sarcoplasmic/endoplasmic reticulum calcium ATPase; SSa; Saikosaponin a; SSb1; saikosaponin b1; SSb2; saik

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

RITA plus 3-MA overcomes chemoresistance of head and neck cancer cells via dual inhibition of autophagy and antioxidant systems

Keywords: 3-MA; 3-methyladenine; ARE; antioxidant response elements; ATG5; autophagy related 5; CI; combination index; DCF-DA; 2′,7′-dichlorofluorescein diacetate; GSH; glutathione; HNC; head and neck cancer; IHC; immunohistochemistry; LC3; microtubule-associat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

ROS-AKT-mTOR axis mediates autophagy of human umbilical vein endothelial cells induced by cooking oil fumes-derived fine particulate matters in vitro

Keywords: PM2.5; Fine particulate matter of < 2.5 µm in aerodynamic diameter; COFs; Cooking oil fumes; LBW; Low birth weight; ROS; Reactive oxygen species; PI3K; Phosphatidylinositol 3-kinase; mTOR; Mechanistic target of rapamycin; HUVECs; Human umbilical vein en

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Local intra-articular injection of resveratrol delays cartilage degeneration in C57BL/6 mice by inducing autophagy via AMPK/mTOR pathway

Keywords: Resveratrol; Osteoarthritis; Autophagy; AMP activated protein kinase; Mammalian target of rapamycin; ADAMTS5; a disintegrin and metalloproteinase with thrombospondin motifs 5; AMPK; AMP activated protein kinase; DMM; destabilization of the medial meniscu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Hsp90 inhibitor geldanamycin attenuates the cytotoxicity of sunitinib in cardiomyocytes via inhibition of the autophagy pathway

Keywords: 3-MA; 3-methyladenine; CQ; chloroquine diphosphate; DMSO; dimethyl sulfoxide; Hsp; heat shock protein; LC3; microtubule-associated protein light chain 3; LDH; lactate dehydrogenase; NH4Cl; ammonium chloride; Autophagy; Cardiotoxicity; Hsp90 inhibitor; Hum

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Autophagy contributes to 4-Amino-2-Trifluoromethyl-Phenyl Retinate-induced differentiation in human acute promyelocytic leukemia NB4 cells

Keywords: AML; acute myeloid leukemia; APL; acute promyelocytic leukemia; ATRA; all-trans retinoic acid; ATPR; 4-Amino-2-Trifluoromethyl-Phenyl Retinate; 3-MA; 3-methyladenine; RAPA; rapamycin; ATO; arsenic trioxide; siRNA; small interfering RNA; MDC; monodansylcad

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Fluvastatin Prevents Lung Adenocarcinoma Bone Metastasis by Triggering Autophagy

Keywords: SREs; skeletal-related events; HMG-CoA; 3-hydroxy-3-methylglutaryl coenzyme A; 3-MA; 3-methyadenine; Baf A1; Bafilomycin A1; MICA; MHC class I chain-related protein A; CQ; chloroquine; PFTα; pifithrin-α; ACC; acetyl-CoA carboxylase; ECM; extracellular m

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Autophagy plays a positive role in zinc-induced apoptosis in intestinal porcine epithelial cells

Keywords: Zn; zinc; IPEC; intestinal porcine epithelial cells; LC3; light chain 3; 3-MA; 3-Methyladenine; ACTB; β-actin; BCL2; B-cell CLL/lymphoma 2; BAX; BCL2-associated X protein; CYCS; Cytochrome c, somatic; CASP3; caspase 3; CASP8; caspase 8; Zinc; IPEC-J2; Ap

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

URB597 improves cognitive impairment induced by chronic cerebral hypoperfusion by inhibiting mTOR-dependent autophagy

Keywords: 3-MA; 3-methyladenine; ACSF; artificial cerebrospinal fluid; AD; Alzheimer's disease; BCCAO; bilateral common carotid artery occlusion; CCH; chronic cerebral hypoperfusion; CNS; central nervous system; ECS; endocannabinoid system; EM; electron microscop

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

An autophagic mechanism is involved in the 6-hydroxydopamine-induced neurotoxicity in vivo

Keywords: 6-OHDA; 6-hydroxydopamine; 3-MA; 3-methylademine; SN; substantia nigra; UP; Subiquitin-proteasome system; TH; tyrosine hydroxylase; TUNEL; terminal deoxynucelotidyl transferase-mediated deoxyuridine triphosphate nick end labeling; TEM; transmission electr

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Cancer-associated Fibroblasts Promote Irradiated Cancer Cell Recovery Through Autophagy

Keywords: Cancer-associated fibroblast; Cytokines; Intermediate metabolite; Autophagy; Tumor relapse; Radiation therapy; CAFs; cancer-associated fibroblasts; IGF1/2; insulin-like growth factor 1/2; CXCL12; C-X-C motif chemokine ligand 12; ROS; reactive oxygen speci

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Scandenolone, a natural isoflavone derivative from Cudrania tricuspidata fruit, targets EGFR to induce apoptosis and block autophagy flux in human melanoma cells

Keywords: Baf A1; bafilomycin A1; CQ; chloroquine; 3-MA; 3-methyladenine; DARTS; drug affinity responsive target stability; EGFR; epidermal growth factor receptor; PARP; poly (ADP-ribose) polymerase; PI; propidium iodide; Apoptosis; Autophagy flux; EGFR; Scandenolo

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleOV6+ cancer stem cells drive esophageal squamous cell carcinoma progression through ATG7-dependent β-catenin stabilization

Keywords: ESCC; CSCs; OV6; ATG7; β-Catenin; ESCC; esophageal squamous cell carcinoma; CSCs; cancer stem cells; CK; cytokeratin; ATG7; autophagy-related gene 7; RT-PCR; real time polymerase chain reaction; OS; overall survival; IHC; immunohistochemistry; 3-MA; 3-Me

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Arsenic sulfide induces apoptosis and autophagy through the activation of ROS/JNK and suppression of Akt/mTOR signaling pathways in osteosarcoma

Keywords: OS; osteosarcoma; ROS; reactive oxygen species; 3-MA; 3-methyladenine; RA; rapamycin; NAC; NAcetyl-L-cysteine; CCK8; Cell Counting Kit-8; PARP; poly (ADPribose) polymerase; MMP; mitochondrial membrane potential; MAPK; mitogen-activated protein kinase; ERK

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Endothelial deletion of mTORC1 protects against hindlimb ischemia in diabetic mice via activation of autophagy, attenuation of oxidative stress and alleviation of inflammation

Keywords: 3-MA; 3-methyladenine; 3-NT; 3-nitrotyrosine; AI; apoptosis index, α-SMA, α-smooth muscle actin; bFGF; basic fibroblast growth factor; BM; bone marrow; CCK-8; cell counting kit-8; CLI; critical limb ischemia; DAPI; 49, 6-diamidino-2-phenylindole; DCFH-D

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Inhibition of ROS production, autophagy or apoptosis signaling reversed the anticancer properties of Antrodia salmonea in triple-negative breast cancer (MDA-MB-231) cells

Keywords: Antrodia salmonea; Triple-negative breast cancer; Autophagy; Apoptosis; ROS; ΔΨm; mitochondrial membrane potential; 3-MA; 3-methyladenine; AS; Antrodia salmonea; ATG7; Autophagy-related 7; AVO; acidic vesicular organelle; BSO; buthionine sulfoximine; CQ

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

The alteration of autophagy and apoptosis in the hippocampus of rats with natural aging-dependent cognitive deficits

Keywords: MWM; Morris water maze; HE; Hematoxylin-eosin; Bax; Bcl-2 associated X Protein; Bcl-2; B-cell lymphoma-2; ULK-1; unc-51-like kinase 1; Beclin-1; B cell lymphoma/leukemia-2 binding protein 1; LC3; light chain 3; Akt; protein kinase B; PI3K; phosphatidylino

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Autophagy inhibits C2-ceramide-mediated cell death by decreasing the reactive oxygen species levels in SH-SY5Y cells

Keywords: Atg; autophagy-related proteins; mTOR; mammalian target of rapamycin; Akt/PKB; protein kinase B; JNK; c-Jun N-terminal kinase; ROS; reactive oxygen species; ERK; extracellular signal-regulated kinase; 3-MA; 3-methyadenine; H2DCFDA; 2′,7′-dichlorofluor

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Role of Microglia Autophagy in Microglia Activation After Traumatic Brain Injury

Keywords: Apoptosis; Autophagy; Microglia; Traumatic brain injury; 3-MA; 3-Methyladenine; Iba-1; Ionized calcium-binding adapter molecule 1; ICV; Intracerebroventricular; IL-1β; Interleukin-1β; LC3; Protein light chain 3; mTOR; Mammalian target of rapamycin; PBS;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Inhibition of autophagy enhances Hydroquinone-induced TK6 cell death

Keywords: Autophagy; Hydroquinone; Apoptosis; 3-MA; CQ; PARP-1;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

The cycloartane triterpenoid ADCX impairs autophagic degradation through Akt overactivation and promotes apoptotic cell death in multidrug-resistant HepG2/ADM cells

Keywords: 3-MA; 3-methyladenine; ADCX; 25-O-acetyl-7,8-didehydrocimigenol 3-O-beta-D-xylopyranoside; TCM; traditional Chinese medicine; HCC; hepatocellular carcinoma; ABC; ATP-binding cassette; ULK1; unc-51-like kinase 1; HCQ; hydroxychloroquine; CTSB; cathepsin B;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Deficiencies in mitochondrial dynamics sensitize Caenorhabditis elegans to arsenite and other mitochondrial toxicants by reducing mitochondrial adaptability

Keywords: OMM; outer mitochondrial membrane; DRP1; dynamin-related protein-1; MFN1; mitofusin 1; MFN2; mitofusin 2; mtDNA; mitochondrial DNA; PINK1; PTEN-induced putative kinase 1; PARK2; parkin; DOA; dominant optic atrophy; CMT2A; Charcot-Marie-Tooth neuropathy ty

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

CQ synergistically sensitizes human colorectal cancer cells to SN-38/CPT-11 through lysosomal and mitochondrial apoptotic pathway via p53-ROS cross-talk

Keywords: CRC; Colorectal cancer; CQ; chloroquine; 3-MA; 3-methyladenine; ROS; reactive oxygen species; LMP; lysosomal membrane potential; ∆ψm; mitochondrial membrane potential; NAC; N-acetyl-L-cysteine; Vit-C; vitamin C; DMSO; dimethyl sulfoxide; Pep-A; pepstat

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2017 سفارش ترجمه

Deep hypothermia-enhanced autophagy protects PC12 cells against oxygen glucose deprivation via a mitochondrial pathway

Keywords: DHCA; deep hypothermic circulatory arrest; DH; deep hypothermia; OGD; oxygen glucose deprivation; I/R; ischemia/reperfusion; CytC; cytochrome c; PARP; poly-ADP-ribose polymerase; PC12; a cell line derived from a pheochromocytoma of the rat adrenal medulla

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Vitamin D3 supplementation alleviates rotavirus infection in pigs and IPEC-J2 cells via regulating the autophagy signaling pathway

Keywords: 3-MA; 3-Methyladenine; Baf A1; bafilomycin A1; LC3-I; microtubule-associated protein light chain 3-I; LC3-II; microtubule-associated protein light chain 3-II; MOI; multiplicity of infection; NSP4; nonstructural protein 4; Rap; rapamycin; RIG-I; retinoic a

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibitions of mTORC1 and 4EBP-1 are key events orchestrated by Rottlerin in SK-Mel-28 cell killing

Keywords: Rottlerin; AMPK; mTOR; 4EBP-1; Autophagy; Protein synthesis; RPMI; Roswell Park Memorial Institute (RPMI); Becl-1; beclin-1; AMPK; AMP-activated protein kinase; ACC; acetyl-CoA carboxylase; mTOR; mammalian target of rapamycin; raptor; regulatory-associate

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

3,3′-Diindolylmethane induces anti-human gastric cancer cells by the miR-30e-ATG5 modulating autophagy

Keywords: DIM; 3,3′-diindolylmethane; LC3; microtubule-associated protein light chain; ATG; autophagy-related gene; mRFP; monomeric red fluorescent protein; GFP; green fluorescent protein; siRNA; small interfering RNA; mRNA; messenger RNA; miRNA; microRNA; MREs;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

AT-101 simultaneously triggers apoptosis and a cytoprotective type of autophagy irrespective of expression levels and the subcellular localization of Bcl-xL and Bcl-2 in MCF7 cells

Keywords: 3-MA; 3-Methyladenine; BAF; Bafilomycin A1; STS; Staurosporine; Wt; Wild type; Apoptosis; Autophagy; BH3 mimetic; Bcl-2 family; Caspases;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Cucurbitacin-I induces hypertrophy in H9c2 cardiomyoblasts through activation of autophagy via MEK/ERK1/2 signaling pathway

Keywords: MAPK; mitogen-activated protein kinase; ANP; atrial natriuretic peptide; BNP; brain natriuretic peptide; 3-MA; 3-methyladenine; DMSO; dimethyl sulfoxide; WGA; wheat germ agglutinin; Cucurbitacin-I; Cardiomyocyte hypertrophy; MEK/ERK1/2; Autophagy; U0126;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Momordin Ic couples apoptosis with autophagy in human hepatoblastoma cancer cells by reactive oxygen species (ROS)-mediated PI3K/Akt and MAPK signaling pathways

Keywords: HepG2; human hepatoblastoma; ROS; reactive oxygen species; 3-MA; 3-methyladenine; RAP; rapamycin; NAC; NAcetyl-l-cysteine; PARP; poly (ADP-ribose) polymerase; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; MDC; Monodansylcadaverine; MM

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Involvement of autophagy upregulation in 3,4-methylenedioxymethamphetamine ('ecstasy')-induced serotonergic neurotoxicity

Keywords: MDMA; 3,4-methylenedioxymethamphetamine; LC3; microtubule-associated protein 1 light chain 3; SERT; serotonin transporter; TPH; tryptophan hydroxylase; SSRIs; selective serotonin reuptake inhibitors; 5-HT; 5-hydroxytryptamine (serotonin); 3-MA; 3-methylad

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Autophagy Inhibitor 3-MA Weakens Neuroprotective Effects of Posttraumatic Brain Injury Moderate Hypothermia

Keywords: Apoptosis; Autophagy; Behavioral assessment; Moderate hypothermia; Traumatic brain injury; 3-MA; 3-methyladenine; Als; Autolysosomes; Aps; Autophagosomes; ICV; Intracerebroventricular; LC3; Protein light chain-3; MABP; Mean arterial blood pressure; PBS; P

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Perturbation of redox balance after thioredoxin reductase deficiency interrupts autophagy-lysosomal degradation pathway and enhances cell death in nutritionally stressed SH-SY5Y cells

Keywords: 3-MA; 3-Methyl adenine; AL; autolysosome; AP; autophagosome; ATG; autophagy related; Au; auranofin; Baf A1; bafilomycin A1; CCK-8; cell counting kit-8; CQ; chloroquine; DMEM; Dulbecco's modified eagle medium; DMSO; dimethyl sulfoxide; DTNB; 5,5'-Dithi

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

Sinomenine activation of Nrf2 signaling prevents hyperactive inflammation and kidney injury in a mouse model of obstructive nephropathy

Keywords: CKD; Chronic kidney disease; CRF; Chronic renal failure; RA; Rheumatoid arthritis; ON; Obstructive nephropathy; ROS; Reactive oxygen species; UUO; Unilateral ureteral obstruction; HE; Hematoxylin and eosin; SIN; Sinomenine; LPS; Lipopolysaccharide; 3-MA;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

Unravelling exemestane: From biology to clinical prospects

Keywords: AI(s); aromatase inhibitor (s); AKT; protein kinase B; AREG; amphiregulin; BMD; bone mineral density; CYP; cytochrome P450; DHEAS; dehydroepiandrosterone sulfate; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; EMA; European Medicine

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

AP1S3 Mutations Cause Skin Autoinflammation by Disrupting Keratinocyte Autophagy and Up-Regulating IL-36 Production

Keywords: 3-MA; 3-methyladenine; AID; autoinflammatory disorder; CRISPR; clustered regularly-interspaced short palindromic repeats; Cas9; CRISPR-associated endonuclease 9; GFP; green fluorescent protein; MALP-2; macrophage-activating lipopeptide 2; siRNA; small int

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Autophagy: A double-edged sword in intervertebral disk degeneration

Keywords: IVD; intervertebral disk; NP; nucleus pulposus; AF; annulus fibrosus; CEPs; cartilaginous endplates; ECM; extracellular matrix; Col II; type II collagen; Col I; type I collagen; IDD; intervertebral disk degeneration; LBP; low back pain; miRNAs; microRNAs;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

A SIRT3/AMPK/autophagy network orchestrates the protective effects of trans-resveratrol in stressed peritoneal macrophages and RAW 264.7 macrophages

Keywords: AAPH; 2,2′-azobis (2-amidinopropane) dihydrochloride; AMPK; AMP-activated protein kinase; ComC; compound C; Edar; edaravone; 3-MA; 3-methyladenine; MMP; mitochondrial membrane potential; Rapa; rapamycin; Resv; trans-resveratrol; VitC; vitamin C; Autopha

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2016 سفارش ترجمه

Autophagy in the eye: Development, degeneration, and aging

Keywords: Autophagy; Retina; Chaperone mediated autophagy; Lysosomes; Mitophagy; Retinal ganglion cells; Retinal pigment epithelial cells; Photoreceptor; Glaucoma; Macular degeneration; Retinal dystrophies; Diabetic retinopathy; 3-MA; 3-methyl adenine; 8-OH DPAT; 8

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2016 سفارش ترجمه

Comparative study of the effects of PM1-induced oxidative stress on autophagy and surfactant protein B and C expressions in lung alveolar type II epithelial MLE-12 cells

Keywords: 3-MA; 3-methyladenine; CAT; catalase; DCFH-DA; 2′,7′-dichlorofluorescein diacetate; ECL; enhanced chemiluminescence; ESR; electron spin resonance; LC3; microtubule-associated proteins light chain 3; NAC; N-acetylcysteine; PM; ambient airborne particul

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of MEK/ERK activation attenuates autophagy and potentiates pemetrexed-induced activity against HepG2 hepatocellular carcinoma cells

Keywords: 3-MA; 3-methyladenine; Baf A1; Bafilomycin A1; Cq; chloroquine; ELISA; enzyme-linked immunosorbent assay; ERK; extracellular-signal-regulated kinase; GFP; green fluorescence protein; MEK; mitogen-activated protein kinase/ERK kinase; LC-3; light chain 3; H

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه