دانلود مقالات ISI درباره 3-Ma + ترجمه فارسی

Citreoviridin induces ROS-dependent autophagic cell death in human liver HepG2 cells

Keywords: Citreoviridin; Autophagy; Reactive oxygen species; Human liver HepG2 cells; CIT; citreoviridin; ROS; reactive oxygen species; NAC; N-acetyl cysteine; 3-MA; 3-methyladenine; MTT; 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide; LC50; median

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Selective autophagy: Xenophagy

Keywords: CFU; Colony Formation Unit; EGFP; Enhanced Green Fluorescent Protein; IRPs; Iron Regulatory Proteins; LC3; Light Chain 3; LAP; LC3 Associated Phagocytosis; MDC; monodansylcadaverine; NOD2; NOD-Like Receptor 2; QIRs; Quiescent Intracellular Reservoirs; RFP

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Targeting pyruvate kinase M2 contributes to radiosensitivity of non-small cell lung cancer cells in vitro and in vivo

Keywords: NSCLC; non-small cell lung cancer; PKM2; pyruvate kinase M2 isoform; pshRNA; the plasmid encoding a short hairpin RNA; IR; ionizing radiation; PEP; phosphoenolpyruvate; 3-MA; 3-methyladenine; Z-VAD; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl keto

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

TNF compromises lysosome acidification and reduces α-synuclein degradation via autophagy in dopaminergic cells

Keywords: TNF; tumor necrosis factor-α; PD; Parkinson's disease; α-SYN; α-synuclein; DA; dopamine; CQ; chloroquine; CM; conditioned medium; LPS; lipopolysaccharide; CHX; cycloheximide; 3-MA; 3-methyladenine; tf-LC3; RFP-GFP-tandem fluorescent LC3; TFEB; transcri

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The yeast Saccharomyces cerevisiae: An overview of methods to study autophagy progression

Keywords: 3-MA; 3-methyladenine; Atg; autophagy related; CRISPR; Clustered Regularly Interspaced Short Palindromic Repeats; GFP; green fluorescent protein; PAS; phagophore assembly site; PKA; protein kinase A; PMN; piecemeal microautophagy of the nucleus; TEM; tran

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

XRCC4 deficiency in human subjects causes a marked neurological phenotype but no overt immunodeficiency

Keywords: DNA double-strand break repair; nonhomologous end-joining; double-strand break repair deficiency; XRCC4/LIG4; immunodeficiency; microcephaly; CID; Combined immunodeficiency; CS; Cockayne syndrome; CSR; Class-switch recombination; DNA-PK; DNA-dependent pro

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Polyphyllin I induced-apoptosis is enhanced by inhibition of autophagy in human hepatocellular carcinoma cells

Keywords: Polyphyllin I; Autophagy; Apoptosis; Antiproliferation; Human hepatocellular carcinoma cell; DMSO; dimethyl sulfoxide; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; 3-MA; 3-methyladenine; Rap; rapamycin; Baf A1; bafilomycin A1; EdU; 5

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular and cellular pharmacologyBlockade of autophagy enhances proapoptotic potential of BI-69A11, a novel Akt inhibitor, in colon carcinoma

Keywords: 3-MA; 3-methyladenine; CQ; Chloroquine; Atg; Autophagy related protein; Autophagy; Colon cancer; Apoptosis; Beclin-1; BI-69A11; HSP90;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Ferritin-stimulated lipid peroxidation, lysosomal leak, and macroautophagy promote lysosomal “metastability” in primary hepatocytes determining in vitro cell survival

Keywords: ACD; accidental (necrotic) cell death; AO; acridine orange; CM; conditioned medium; DAPI; 4′,6-diamidino-2-phenylindole; DFO; desferrioxamine mesylate; EGF; epidermal growth factor; ELC; endo-/lysosomal compartment; GFL; green AO fluorescence; GSH; glut

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Exemestane metabolites suppress growth of estrogen receptor-positive breast cancer cells by inducing apoptosis and autophagy: A comparative study with Exemestane

Keywords: Estrogen receptor-positive breast cancer; Aromatase inhibitors; Exemestane metabolites; Apoptosis; Autophagy; Acquired-resistance; AIs; aromatase inhibitors; AO; acridine orange; AVOs; acid vesicular organelles; CCCP; carbonyl cyanide m-chlorophenylhydraz

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Autophagy exacerbates caspase-dependent apoptotic cell death after short times of starvation

Keywords: 3-Methyladenine (Pubmed CID 1673); Camptothecin (Pubmed CID 24360); Etoposide (Pubmed CID 36462); 7-Bromoindirubin-3-oxime (Pubmed CID 11846148); Necrostatin-1 (Pubmed CID 282833); Q-VD-OPh (Pubmed CID 11237609); 2-Phenylethynesulfonamide (Pubmed CID 3276

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Autophagy protects intestinal epithelial Cells against Deoxynivalenol toxicity by alleviating oxidative stress via IKK signaling pathway

Keywords: DON; deoxynivalenol; ATG; autophagy-related; FACS; fluorescence activated cell sorting; 3-MA; 3-methyladenine; WT; wild type; PI; propidium iodide; LC3-II; microtubule-associated protein 1 light chain 3 beta; IKK; The IκB kinase; AMPK; AMP-activated prot

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2015 سفارش ترجمه

5-Demethylnobiletin promotes the formation of polymerized tubulin, leads to G2/M phase arrest and induces autophagy via JNK activation in human lung cancer cells

Keywords: PMF; polymethoxyflavone; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; 3-MA; 3-methyladenine; NSCLC; non-small-cell lung carcinoma; T-4-ol; terpinen-4-ol; 5-DMN; 5-demethylnobiletin; Col; colchicine; SP; SP610025; 5-Demethylnobiletin;

دانلود رایگان متن کامل مقاله ISI 65 صفحه سال انتشار : 2015 سفارش ترجمه

Dramatic suppression of colorectal cancer cell growth by the dual mTORC1 and mTORC2 inhibitor AZD-2014

Keywords: 3-MA; 3-methyaldenine; 4E-BP1; eukaryotic initiation factor 4E-binding protein 1; mTOR; mammalian target or rapamycin; mTORC1; mTOR complex 1; mTORC2; mTOR complex 2; S6K; p70-S6 Kinase 1; LC3B; light chain 3B; Colorectal cancer; AZD-2014; mTOR complexes;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Comparison of the biological effects of MMS and Me-lex, a minor groove methylating agent: Clarifying the role of N3-methyladenine

Keywords: AP; apurinic/apyrimidinic; apn1apn2; AP endonucleases 1 and 2 defective; BER; base excision repair; 3-mA; N3-methyladenine; 3-m-c3A; 3-methyl-3-deazaadenine; mag1; 3-methyladenine-DNA glycosylase 1 defective; Me-lex; {1-methyl-4-[1-methyl-4-(3-methoxysulf

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Modulating autophagy affects neuroamyloidogenesis in an in vitro ischemic stroke model

Keywords: Aβ; β-amyloid; AD; Alzheimer's disease; APP; amyloid precursor protein; DMEM; Dulbecco's-Modified Essential Medium; ELISA; enzyme-linked immunosorbent assay; FBS; fetal bovine serum; LDH; lactate dehydrogenase; l-NBP; l-3-n-butylphthalide; 3-MA; 3-m

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration

Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors; ATP; adenosine triphosphate; Aβ; amyloid β peptide; AD; Alzheimer's disease; APP; amyloid precursor protein; AMP; adenos

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of AMPK protects against hydrogen peroxide-induced osteoblast apoptosis through autophagy induction and NADPH maintenance: New implications for osteonecrosis treatment?

Keywords: 3-MA; 3-methyladenine; ALP; alkaline phosphotase; AMPK; AMP-activated protein kinase; ACC; acetyl-CoA carboxylase; H2O2; hydrogen peroxide; NADPH; nicotinamide adenine dinucleotide phosphate; LC3B; light chain 3B; ROS; reactive oxygen species; Hydrogen pe

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

MTOR-independent induction of autophagy in trabecular meshwork cells subjected to biaxial stretch

Keywords: TM; trabecular meshwork; IOP; intraocular pressure; ATG; autophagy-related genes; CTSB; cathepsin B; BECN1; beclin; TUBB; beta tubulin; SQSTM; sequestosome; tfLC3; tandem fluorescence LC3; GFP; green fluorescence protein; RFP; red fluorescence protein; m.

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Increased CHO cell fed-batch monoclonal antibody production using the autophagy inhibitor 3-MA or gradually increasing osmolality

Keywords: Autophagy; 3-MA; Osmolality; Glycosylation; Fed-Batch; Recombinant protein production

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Interplay between autophagy and apoptosis mediated by copper oxide nanoparticles in human breast cancer cells MCF7

Keywords: NAC; N-acetyl cysteine; MDC; monodansylcadaverine; 3-MA; 3-methyladenine; mM; milli molar; Copper oxide nanoparticle; Autophagy; Apoptosis; Small interfering RNA;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Degradation of AF1Q by chaperone-mediated autophagy

Keywords: 3-MA; 3-methyladenine; 6-AN; 6-aminonicotinamide; AML; acute myeloid leukemia; CMA; chaperone-mediated autophagy; CQ; chloroquine; HBSS; Hanks balanced salt solution; HSPA8; heat shock 70 kDa protein 8; LAMP-2 A; lysosome-associated membrane protein 2A; A

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

The links between AKT and two intracellular proteolytic cascades: Ubiquitination and autophagy

Keywords: BRCA1; breast cancer susceptibility gene 1; BRCT; Brca1 C-terminal; CHIP; chaperone-associated ubiquitin ligase; CYLD; cylindromatosis; DAPK; death-associated protein kinase; DUB; deubiquitinating enzyme); EGF; epidermal growth factor; FADD; fas-associate

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of PI3K/Akt signaling in rostral ventrolateral medulla impairs brain stem cardiovascular regulation that underpins circulatory depression during mevinphos intoxication

Keywords: aCSF; artificial cerebrospinal fluid; Akt; serine/threonine protein kinase; EMSA; electrophoretic mobility shift assay; HR; heart rate; LF; low-frequency; 3-MA; 3-methyladenine; NF-κB; nuclear factor-κB; NO; nitric oxide; NOS; nitric oxide synthase; NRS

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Oxidative damage to osteoblasts can be alleviated by early autophagy through the endoplasmic reticulum stress pathway-Implications for the treatment of osteoporosis

Keywords: 7-AAD; 7-aminoactinomycin D; Baf-A1; bafilomycin-A1; CAT; catalase; DCFH-DA; 2′-,7′-dichlorofluorescein diacetate; E64d; (2S,3S)-trans-epoxysuccinyl-L-leucylamido-3-methylbutane ethyl ester; ER; endoplasmic reticulum; JC-1; 5,5′,6,6′-tetrachloro-1

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Molecular and cellular pharmacologyExtracellular signal-regulated kinase, receptor interacting protein, and reactive oxygen species regulate shikonin-induced autophagy in human hepatocellular carcinoma

Keywords: 3-MA; 3-Methyladenine; ALT; Alanine transaminase; AO; Acridine orange; AVO; Acidic vesicular organelles; CMC; Carboxymethyl Cellulose; CML; Chronic myelogenous leukemia; CCTCC; China center for type culture collection; CQ; Chloroquine; DCFDA; Dichlorofluo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Involvement of apoptosis and autophagy in the death of RPMI 8226 multiple myeloma cells by two enantiomeric sigma receptor ligands

Keywords: AI; apoptosis inhibitor; Bmax; maximal ligand binding sites; BODIPY 665/676 C11; 4-difluoro-3,5-bis(4-phenyl-1,3-butadienyl)-4-bora-3a,4a-diaza-s-indacene; DCFDA; 2′,7′-dichlorofluorescein diacetate; DAPI; 4,6-diamino-2-phenylindole; DMSO; dimethylsul

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Role of the ubiquitin-proteasome system in brain ischemia: Friend or foe?

Keywords: 3-MA; 3-methyladenine; 15d-PHJ2; 15-deoxy-Δ12,14-prostaglandin J2; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole proprionic acid; AMPAR; AMPA receptors; APC/C; anaphase-promoting complex/cyclosome; APV; D-aminophosphonovalerate; ATF4; activating transcri

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2014 سفارش ترجمه

Sorafenib overcomes the chemoresistance in HBx-expressing hepatocellular carcinoma cells through down-regulation of HBx protein stability and suppresses HBV gene expression

Keywords: 3-MA; 3-methyladenine; AIF; apoptosis-inducing factor; BAF; Bafilomycin A1; CQ; Chloroquine; HBV; Hepatitis B virus; HBx; Hepatitis B virus X; HCC; Hepatocellular carcinoma; IFNα; interferon alpha; LC3II; dynein light chain 3; MMP; mitochondrial membrane

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2014 سفارش ترجمه

Autophagy inhibition switches low-dose camptothecin-induced premature senescence to apoptosis in human colorectal cancer cells

Keywords: CRC; colorectal cancer; CPT; camptothecin; DSBs; double-strand breaks; DDR; DNA damage response; γ-H2AX; phosphorylated histone H2AX; ATM; ataxia telangiectasia mutated; Chk2; check-point kinase; AMPK; AMP-activated protein kinase; TSC2; tuberous scleros

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2014 سفارش ترجمه

Wogonoside induces autophagy in MDA-MB-231 cells by regulating MAPK-mTOR pathway

Keywords: 3-MA; 3-methyladenine; AO; acridine orange; MAP-LC3; microtubule-associated protein-light chain 3; MDC; monodansylcadaverine; mTOR; mammalian target of rapamycin; p70S6K; p70-S6 kinase; PKCδ; protein kinase Cδ; TEM; transmission electron microscopy; Wog

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Evodiamine, a plant alkaloid, induces calcium/JNK-mediated autophagy and calcium/mitochondria-mediated apoptosis in human glioblastoma cells

Keywords: 2-APB; 2-aminoethoxydiphenyl borate; 3-MA; 3-methyladenine; AIF; apoptosis-inducing factor; AVO; acidic vesicular organelle; [Ca2+]i; intracellular calcium; Evo; evodiamine; JC-1; 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazol-carbocyanine

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

The role of elevated autophagy on the synaptic plasticity impairment caused by CdSe/ZnS quantum dots

Keywords: Autophagy; LC3-I/II; QDs; Synaptic plasticity; Synapsin-I; Synapse density; QD; quantum dot; LC3; light chain protein 3; PE; phosphatidylethanolamine; mTOR; mammalian target of rapamycin; LTP; long-term potentiation; I/O; input/output; PPF; paired-pulse f

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Azathioprine desensitizes liver cancer cells to insulin-like growth factor 1 and causes apoptosis when it is combined with bafilomycin A1

Keywords: ERK; extracellular signal-regulated kinase; TSC-2; tuberous sclerosis 2 protein; mTOR; mammalian target of rapamycin; IRS; insulin receptor substrate; PI3K; phosphoinositide-3-kinase; AKT; protein kinase B; MAPK; mitogen-activated protein kinase; FOXO1; f

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of a small molecule that induces ATG5-and-cathepsin-l-dependent cell death and modulates polyglutamine toxicity

Keywords: APH; aphidicolin; ATG; Autophagy gene; DKO; double knockout; 3-MA; 3-methyl adenine; HU; Hydroxyurea; MEF; mouse embryo fibroblasts; NID; Novel inducer of death; PI3K; phosphotidyl inositol 3-kinase; RIP-1; Receptor Interacting Protein-1, STS, staurospori

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Propofol prevents cerebral ischemia-triggered autophagy activation and cell death in the rat hippocampus through the NF-κB/p53 signaling pathway

Keywords: 3-MA; 3-methyladenine; ANOVA; analysis of variance; BSA; bovine serum albumin; DMSO; dimethylsulfoxide; DRAM; damage-regulated autophagy modulator; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; H/I; hypoxia-ischemia; I/R; ischemia-reperfusion; PaCO

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2013 سفارش ترجمه

Human papillomavirus infection is inhibited by host autophagy in primary human keratinocytes

Keywords: HPV; Papillomavirus; Keratinocyte; HFK; Trafficking; Entry; Autophagy; Autophagosome; 3-MA; 3-methyladenine

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Targeting autophagy as a potential therapeutic approach for melanoma therapy

Keywords: 5-ALA; 5-aminolevulinic acid; AMBRA1; autophagy/Beclin 1 regulator 1; APC; antigen-presenting cell; ASS; argininosuccinate synthetase; ATG; autophagy-related; ATM; Ataxia telangiectasia mutated; BafA1; bafilomycin A1; Bif-1; endophilin B1; BN; benign nevi

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2013 سفارش ترجمه

Aluminum maltolate induces primary rat astrocyte apoptosis via overactivation of the class III PI3K/Beclin 1-dependent autophagy signal

Keywords: Al; aluminum; 3-MA; 3-methyladenine; ROS; reactive oxygen species; AD; Alzheimer's diseases; PD; Parkinson's diseases; ALS; amyotrophic lateral sclerosis; HD; Huntington's diseases; Astrocyte; Aluminum; Autophagy; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

H1-antihistamines induce vacuolation in astrocytes through macroautophagy

Keywords: HTMT; trifluoromethyl toluidide; V-ATPase; vacuolar-ATPase; 3-MA; 3-methyladenine; MDC; monodansylcadaverine; BSA; bovine serum albumin; PBS; phosphate-buffered saline; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; Astrocyte; H1-antihistamine; Macroaut

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

The ubiquitin ligase F-box/G-domain protein 1 promotes the degradation of the disease-linked protein torsinA through the ubiquitin-proteasome pathway and macroautophagy

Keywords: AP; alkaline phosphatase; CASA; chaperone-assisted selective autophagy; ER; endoplasmic reticulum; ERAD; endoplasmic reticulum-associated degradation; FBG1; F-box/G-domain protein 1; H&E; hematoxylin and eosin; KI; knock in; KO; knock out; 3-MA; 3-methyla

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Autophagy Attenuates the Adaptive Immune Response by Destabilizing the Immunologic Synapse

Keywords: Inflammatory Bowel Disease; Immune Regulation; Cellular Interactions; Th17; 3-MA; 3-methyladenine; BMDC; bone marrow-derived dendritic cell; DC; dendritic cell; GFP; green fluorescent protein; ICAM-1; intercellular adhesion molecule 1; IL; interleukin;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

SK&F 96365 induces apoptosis and autophagy by inhibiting Akt-mTOR signaling in A7r5 cells

Keywords: TRP channel; transient receptor potential channel; VSMC; vascular smooth muscle cell; 3-MA; 3-methyladenine; SK&F 96365; Apoptosis; Autophagy; Akt-mTOR signaling; TRP channel;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Sensitizing effect of 3-methyladenine on radiation-induced cytotoxicity in radio-resistant HepG2 cells in vitro and in tumor xenografts

Keywords: Liver cancer; Radio-resistance; Autophagy; 3-MA; 3-methyladenine; AO; acridine orange; AVOs; acidic vesicular organelles; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HCC; hepatocellular carcinoma; IR; ionizing radiation; mTOR; mammalian target of rap

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Inhibiting NF-κB activation and ROS production are involved in the mechanism of silibinin's protection against D-galactose-induced senescence

Keywords: CAT; catalase; d-gal; d-galactose; GSH-pX; glutathione-peroxidase; ITI; inter-trial interval; 3-MA; 3-methyladenine; MDA; malondialdehyde; MDC; Monodansylcadaverine; NF-κB; nuclear factor-κB; PDTC; pyrrolidine-carbodithioic acid ammonium salt; Rapa; rap

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Loss of PINK1 function decreases PP2A activity and promotes autophagy in dopaminergic cells and a murine model

Keywords: 3-MA; 3-methyl adenine; LC3; microtubule-associated protein light chain-3; mTOR; mammalian target of rapamycin; PD; Parkinson's disease; PI3K-III; phosphoinositide 3-kinase III; PINK1; PTEN-induced kinase 1; PP2A; protein phosphatase 2A; PINK1; PP2A; Au

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Targeting autophagy during cancer therapy to improve clinical outcomes

Keywords: AMPK; AMP activated protein kinase; ATG; autophagy-related genes; Bif-1; endophilin B1; BNIP3; Bcl-2/adenovirus E1B 19 kDa-interacting protein; CML; chronic myeloid leukemia; CQ; chloroquine; DAP1; death-associated protein 1; HCQ; hydroxychloroquine; HDA

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Research ReportSilencing of PINK1 induces mitophagy via mitochondrial permeability transition in dopaminergic MN9D cells

Keywords: PINK1; Autophagy; Beclin 1; Mitochondrial permeability transition; Mitophagy; PD; Parkinson's disease; SNpc; substantia nigra pars compacta; PINK1; PTEN-induced putative kinase 1; 3-MA; 3-methyladenine; shRNA; short hairpin RNA; Tet; tetracycline; MPT; mi

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Autophagy inhibition sensitizes multiple myeloma cells to 17-dimethylaminoethylamino-17-demethoxygeldanamycin-induced apoptosis

Keywords: 3-MA; 17DMAG; Apoptosis; Autophagy; Multiple myeloma

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Downregulation of active IKKβ by Ro52-mediated autophagy

Keywords: TNF; tumor necrosis factor; HTLV-1; human T-cell leukemia virus type 1; HEK; human embryonic kidney; HA; hemagglutinin; RH; RGS-poly His; PCR; polymerase chain reaction; mRFP; monomeric red fluorescent protein; EGFP; enhanced green fluorescent protein; PB

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه