Keywords: 3-NT; 3-Nitrotyrosine; AGE(s); advanced glycation end product(s); IF; immunofluorescence; IHC; immunohistochemistry; iNOS; inducible nitric oxide synthase; NF-κB; nuclear factor kappa B; RT; room temperature; Pancreatic islets; Aging; Cellular senescence
مقالات ISI (ترجمه نشده)
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Keywords: WD; Western diet; RAAS; renin angiotensin- aldosterone system; CVD; cardiovascular disease; MR; mineralocorticoid receptor; ECMR; endothelial cell mineralocorticoid receptor; DOCA; deoxycorticosterone acetate; SGK1; serum-and glucocorticoid-regulated ki
Keywords: GSNOR; Protein nitration; RNS; ROS; 3-NT; 3-nitrotyrosine; APF; 3â²-(p-aminophenyl) fluorescein; cPTIO; 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide; DAF-FM DA; 4-amino-5-methylamino-20,70-difluorofluorescein diacetate; GSNOR; S-nitr
Keywords: Arginase; Nitrated proteins; NOS-like activity; Putrescine; Seed dormancy; Ubiquitin; 3-NT; 3-nitro-tyrosine; Arg; arginine; cPTIO; 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide; Orn; ornithine; NO2â; nitrite; NO; nitric oxide; NOS-l
Keywords: Dopamine; Ecstasy; Methamphetamine; METH; 3,4-Methylenedioxymethamphetamine; MDMA; Mouse; Neurodegeneration; Neuroinflammation neurotoxicity; Non-human primate; Rat; AC; adenylyl cyclase; AcbSh; nucleus accumbens shell; AcbC; nucleus accumbens core; cAMP;
Keywords: CVD; cardiovascular disease; CKD; chronic kidney disease; EnNaC; endothelial sodium channel; EC; endothelial cell; CD; control diet; WD; western diet; 3-NT; 3-nitrotyrosine; ROS; reactive oxygen species; TLR4; Toll-like receptor 4; XO; xanthine oxidase; V
Keywords: 1-OHP; 1-hydroxypyrene; 3-NT; 3-nitrotyrosine; 8-oxodGuo; 8-oxo-7,8-dihydro-2'-deoxyguanosine; 15-F2t-IsoP; 15-F2t-isoprostane; +dP/ dt; rate of change of pressure development; -dP/dt; rate of change of pressure decay; Ach; acetylcholine; p-AKT; phospho
Keywords: Traumatic brain injury; Chronic traumatic encephalopathy; Tauopathy; Concussion; Repetitive head injury; 2-AG; 2-arachidonoylglycerol; 3-NT; 3-nitrotyrosine; 4-HNE; 4-hydroxynonenal; Ach; acetylcholine; AChEI; acetylcholine esterase inhibitor; AD; Alzheim
Keywords: SCI; spinal cord injury; LPO; lipid peroxidation; NO; nitric oxide; , NOx; nitrate/nitrite; MMPs; matrix metalloproteases; MDA; malondialdehyde; 4-HNE; 4-hydroxynonenal; T8; the 8th thoracic; dpi; days post injury; BBB; Basso-Beattie-Bresnahan; 8-OhdG; 8-
Keywords: Nitric oxide; H2O2; SNAP; Oxidative/nitrosative stress; Antioxidant; Neuron; 3-NT; 3-nitrotyrosine; ANOVA; one-way analysis of variance; CAT; catalase; CBA; Coumarin boronic acid; CNS; central nervous system; COH; hydroxycoumarin; DCFH-DA; 2â²,7'-dichlor
Keywords: DHE; dihydroethidium; MEM; minimum essential medium Eagle; NO; nitric oxide; NOS; nitric oxide synthases; 3-NT; 3-nitrotyrosine; Prx5; peroxiredoxin 5; NO; ROS; Aging; Skeletal muscle; Fluorescent confocal microscopy;
Keywords: ICH; intracerebral hemorrhage; Hb; hemoglobin; BBB; blood-brain barrier; ONOOâ; peroxynitrite; 3-NT; 3-nitrotyrosine; CNS; central nervous system; nNOS; neuronal nitric oxide synthase; eNOS; endothelial nitric oxide synthase; iNOS; inducible nitric ox
Keywords: AHR; airways hyper-responsiveness; BALf; bronchoalveolar lavage fluid; 3-CP; 3 carbamoyl pyrrolidine N-oxyl (3-carbamoyl-proxyl); Dex; dexamethasone; EPR; electron paramagnetic resonance; H&E; hematoxylin and eosin; IL; interleukin; TPL; 4-hydroxy-2,2,6,6
Keywords: 3-NT; 3-Nitrotyrosine; AAP; 4-Aminoantipyrine; DNP; Dinitrophenol; DNPH; 2,4-Dinitrophenylhydrazine; DTNB; 5,5â²-Dithiobis-(2-nitrobenzoic acid); Hb; Hemoglobin; HRP; Horseradish peroxidase; HSA; Human serum albumin; HSA-T; HSA treated with iodine to mod
Keywords: CAT; catalase; eNOS; endothelial nitric oxide synthase; HSP27; heat shock protein 27; HSP72; heat shock protein 72; nNOS; neuronal nitric oxide synthase; PRX5; peroxiredoxin 5; RONS; reactive oxygen and nitrogen species; SOD1; superoxide dismutase 1; SOD2
Keywords: AASA; aminoadipic semialdehyde; AGE; advanced glycation endproduct; AOPP; advanced oxidation protein product; AQC; 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate; BUL; bilateral ureteral ligation; BNX; bilateral nephrectomy; CEL; Nε-(1-carboxyethyl)lysi
Keywords: Cardiotoxicity; Mouse model; Echocardiography; Hemodynamics; cTnI; Cardiac troponin I; Dox; Doxorubicin; ErbB2; Epidermal growth factor receptor type 2; HF; Heart failure; LV; Left ventricular; LVEDV; Left ventricular end-diastolic volume; LVEF; Left vent
Keywords: 3-NT; 3-nitrotyrosine; ADMA; asymmetric dimethyl arginine; Akt; protein kinase B; AMPK; AMP-activated protein kinase; BAT; brown adipose tissue; BH2; dihydrobiopterin; BH4; tetrahydrobiopterin; BMR; basal metabolic rate; Cav-1; caveolin-1; CCK; cholecysto
Keywords: SLE; systemic lupus erythematosus; 3-NT; 3-nitrotyrosine; NO; nitric oxide; O2·-; superoxide anion; RNS; reactive nitrogen species; RA; rheumatoid arthritis; OA; osteoarthritis;
Keywords: 3-NT; 3-nitrotyrosine; ICR; Institute for Cancer Research; ip; intraperitoneal; METH; (+)-methamphetamine hydrochloride; NO; nitric oxide; NOS; nitric oxide synthase; OCT; octreotide; SST; somatostatin; Methamphetamine; Glutamate; Somatostatin; Nitric oxi
Translocator protein (TSPO) and stress cascades in mouse models of psychosis with inflammatory disturbances
Keywords: CBL; cerebellum; CON; control; CSE; cuprizone short-term exposure; HP; hippocampus; HPA; hypothalamic-pituitary-adrenal; MIA; maternal immune activation; PET; positron emission tomography; PFC; prefrontal cortex; poly(I:C); polyinosinic:polycytidylic acid
Resveratrol attenuates testicular apoptosis in type 1 diabetic mice: Role of Akt-mediated Nrf2 activation and p62-dependent Keap1 degradation
Keywords: RSV; resveratrol; STZ; streptozotocin; ROS; reactive oxygen species; RNS; reactive nitrogen species; SOD; superoxide dismutase; Nrf2; nuclear factor erythroid 2-related factor 2; Keap1; kelch-like ECH-associated protein 1; NQO-1; NAD(P)H:quinone oxidoredu
Cholinergic anti-inflammatory pathway inhibits neointimal hyperplasia by suppressing inflammation and oxidative stress
Keywords: 3-NT; 3-nitrotyrosine; α7nAChR; α7 nicotinic acetylcholine receptor; α-SMA; α-smooth muscle actin; CAP; cholinergic anti-inflammatory pathway; CCL2; chemokines chemokine (C-C motif) ligand 2; CNS; central nervous system; CXCL2; chemokine (CXC motif) l
An innate immune response and altered nuclear receptor activation defines the spinal cord transcriptome during alpha-tocopherol deficiency in Ttpa-null mice
Keywords: 3-NT; 3-nitrotyrosine; α-TOH; Alpha-tocopherol; AVED; Ataxia with vitamin E deficiency; CNS; Central nervous system; DET; Differentially expressed transcript; GFAP; Glial fibrillary acidic protein; HE; Hematoxylin and eosin; IHC; Immunohistochemistry; LX
NOD2 expression, DNA damage and oxido-inflammatory status in atopic bronchial asthma: Exploring their nexus to disease severity
Keywords: 3-NT; 3-nitrotyrosine; CHIT1; Chitotriosidase enzyme; FEV1; Forced expiratory volume in 1â¯s; FVC; forced vital capacity; GST; Glutathione-S-transferase; MDA; Malondialdehyde; NLR; Nod-like receptor; Nod2; nucleotide-binding oligomerization domain 2; PAM
Nicotine enhances alcoholic fatty liver in mice: Role of CYP2A5
Keywords: Cotinine; Triglyceride; Metabolism; Oxidative stress; Reactive oxygen species; CYP2A6; 3-NT; nitrotyrosine adducts; ADH; alcohol dehydrogenase; ALD; alcoholic liver disease; ALDH; acetaldehyde dehydrogenase; ALT; alanine transaminase; COH; coumarin 7-hydr
Sodium butyrate attenuates diabetes-induced aortic endothelial dysfunction via P300-mediated transcriptional activation of Nrf2
Keywords: 3-NT; 3-nitrotyrosine; 4-HNE; 4-hydroxynonenal; ACh; acetylcholine; AHR; aryl hydrocarbon receptor; ChIP; chromatin immunoprecipitation; c-NRF2; cytosolic NRF2; Ctrl; control; DM; diabetes mellitus; EC; endothelial cell; HDAC; histone deacetylase; HG; hig
Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress, inflammation and apoptosis in mice
Keywords: 3-NT; 3-nitro-tyrosine; ALI; acute liver injury; ALT; alanine aminotransferase; APAP; acetaminophen; AST; aspartate aminotransferase; CAT; catalase; Cl-Cas-3; cleavage Caspase-3; CYP2E1; cytochrome P450 2E1; ERK1/2; extracellular signal-regulated kinase 1
AMPKα2 deficiency exacerbates long-term PM2.5 exposure-induced lung injury and cardiac dysfunction
Keywords: 3-NT; 3â²-nitrotyrosine; AMPK; AMP-activated protein kinase; AT I; type I alveolar epithelial cell; BALF; bronchoalveolar lavage fluid; COPD; chronic obstructive pulmonary disease; DM; dorsomorphin; FA; filtered air; GSH; reduced glutathione; GSSG; oxidi
The expression of oxidative stress response genes is modulated by a combination of resveratrol and N-acetylcysteine to ameliorate ototoxicity in the rat cochlea
Keywords: Antioxidant therapy; Gpx1; Il1b; Il4; PCR-arrays; Sod1; ABR; Auditory Brainstem Responses; AGs; Aminoglycosides; COX-2; cyclooxygenase 2; DE; Differentially expressed; FC; Fold change; IHC; Inner hair cells; IP; intraperitoneal; IPL; Interpeak latency; NA
ERK1/2/mTOR/Stat3 pathway-mediated autophagy alleviates traumatic brain injury-induced acute lung injury
Keywords: ERK1/2; extracellular signal-regulated kinase 1/2; mTOR; mechanistic target of rapamycin; Stat3; signal transducer and activator of transcription 3; TBI; traumatic brain injury; ALI; acute lung injury; HMGB1; high-mobility group box protein 1; 3-MA; 3âm
Impact of microRNAs on ischemic stroke: From pre- to post-disease
Keywords: AAV; adeno-associated virus; ABCA1; ATP-binding cassette transporter 1; AGO; argonaute; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionate; AT1R; angiotensin II type 1 receptor; AQPs; aquaporins; BBB; blood-brain barrier; Bcl-6; B-cell lymphoma-6;
Research articleThe histone deacetylase inhibitor sodium butyrate protects against noise-induced hearing loss in Guinea pigs
Keywords: 3-NT; 3-nitrotyrosine; DAPI; 4â²,6-diamidino-2-phenylindole; ABR; auditory brainstem response; HATs; histone acetyltransferases; HDACs; histone deacetylases; H3-AcK9; acetyl-histone H3 (Lys9); HC; hair cell; IHC; inner hair cell; NIHL; noise-induced hear
NADPH oxidase contributes to streptozotocin-induced neurodegeneration
Keywords: 3-NT; 3-nitrotyrosine; 4-HNE; 4-hydroxy-2 nonenal; AD; Alzheimer's disease; Aβ; β-amyloid peptide; AIF; apoptosis-inducing factor; IL; interleukins; Nox; NADPH oxidase; RNS; reactive nitrogen species; ROS; reactive oxygen species; STZ; streptozotocin; W
Endothelial deletion of mTORC1 protects against hindlimb ischemia in diabetic mice via activation of autophagy, attenuation of oxidative stress and alleviation of inflammation
Keywords: 3-MA; 3-methyladenine; 3-NT; 3-nitrotyrosine; AI; apoptosis index, α-SMA, α-smooth muscle actin; bFGF; basic fibroblast growth factor; BM; bone marrow; CCK-8; cell counting kit-8; CLI; critical limb ischemia; DAPI; 49, 6-diamidino-2-phenylindole; DCFH-D
Methane ameliorates spinal cord ischemia-reperfusion injury in rats: Antioxidant, anti-inflammatory and anti-apoptotic activity mediated by Nrf2 activation
Keywords: ARE; antioxidant response element; BSCB; blood-spinal cord barrier; CXCL1; C-X-C motif ligand 1; GFAP; glial fibrillary acidic protein; GSH; glutathione; GSSG; glutathione disulfide; HO-1; heme oxygenase-1; H2O2; hydrogen peroxide; Iba-1; ionized calcium-
Influence of the APOE genotype on hepatic stress response: Studies in APOE targeted replacement mice and human liver cells
Keywords: AD; Alzheimer's disease; APOE; apolipoprotein E; ATP; adenosine triphosphate; ATP5A1; ATP synthase subunit alpha, mitochondrial; B2M; beta-2 microglobulin; BAX; BCL2-associated X protein; BCL2; B-cell leukemia/lymphoma 2; BiP; binding immunoglobulin prote
Targeting the nNOS/peroxynitrite/calpain system to confer neuroprotection and aid functional recovery in a mouse model of TBI
Keywords: BH4; tetrahydrobiopterin; CCI; controlled cortical impact; FeTPPS; 5,10,15,20-tetrakis(4-sulfonatophenyl) porphyrinato iron (III); HgCl2; mercuric chloride; GSNO; S-nitrosoglutathione; MBP; myelin basic protein; NeuN; neuronal nuclear protein; 7-NI; 7-nit
Oxidative and Nitrosative Stress and Histone Deacetylase-2 Activity in Exacerbations of COPD
Keywords: COPD; host defense; infection; viral disease; 3-NT; 3-nitrotyrosine; 8-OHdG; 8-hydroxy-2'-deoxyguanosine; GM-CSF; granulocyte-macrophage colony-stimulating factor; GOLD; Global Initiative for Obstructive Lung Disease; HDAC2; histone deacetylase-2; MMP-9;
House dust mite-induced asthma causes oxidative damage and DNA double-strand breaks in the lungs
Keywords: House dust mite; asthma; oxidative stress; DNA double-strand breaks; BEAS-2B; cell death; DNA repair; NU7441; AHR; Airway hyperresponsiveness; ATM; Ataxia-telangiectasia mutated; BAL; Bronchoalveolar lavage; CC10; Club cell 10Â kDa protein; DCFH-DA; 2,7-D
Caveolin-1 protects against hepatic ischemia/reperfusion injury through ameliorating peroxynitrite-mediated cell death
Keywords: I/R; ischemia and reperfusion; RNS; reactive nitrogen species; ROS; reactive oxygen species; O2â¢â; superoxide; ONOOâ; peroxynitrite; SOD; superoxide dismutase; NOS; nitric oxide synthases; iNOS; inducible nitric oxide synthases; NO; nitric oxide; EG
Association of cardiac injury with iron-increased oxidative and nitrative modifications of the SERCA2a isoform of sarcoplasmic reticulum Ca2+-ATPase in diabetic rats
Keywords: Iron; Diabetic heart complications; Tyrosine nitration; SERCA2a; DFO; deferoxamine; DNP; dinitrophenol; DTT; dithiothreitol; HFD; high-fat diet; iNOS; inducible nitric oxide synthase; i.p.; intraperitoneally; NO; nitric oxide; NPD; normal pellet diet; ONO
Oxidative and nitrative stress and pro-inflammatory cytokines in Mucopolysaccharidosis type II patients: effect of long-term enzyme replacement therapy and relation with glycosaminoglycan accumulation
Keywords: 3-NT; 3-nitrotyrosine; ABTS®; 2,2â²-azino-di-3-(ethylbenzthiazoline sulfonate); AChE:Fabâ²; acetylcholinesterase:Fabâ²; CAT; catalase; Cr; creatinine; di-Tyr; di-tyrosine; DNPH; 2,4-dinitrophenylhydrazine; DS; dermatan sulfate; DTNB; 5,5â²-dithiobis-
Cardiac-specific overexpression of catalase prevents diabetes-induced pathological changes by inhibiting NF-κB signaling activation in the heart
Keywords: CAT-TG; cardiac-specific catalase overexpression transgenic; WT; wild type; α-KGD; α-oxoglutarate dehydrogenase E1 component; KGDHC; α-ketoglutarate dehydrogenase complex; ATP-α; ATP synthase α subunit; ATP-β; ATP synthase β subunit; ROS; reactive
Selenite activates the ATM kinase-dependent DNA repair pathway in human osteosarcoma cells with mitochondrial dysfunction
Keywords: Mitochondrial dysfunction; Selenite; DNA repair; ATM kinase; Oxidative damage; ATM; ataxia teleangiectasia mutated kinase; BRCA1; breast cancer 1; DAF-FM; 4-Amino-5-methylamino-2â²,7â²-difluorofluorescein; DAPI; 4â²,6-diamidino-2-phenylindole; DBS; dou
OKN-007 decreases free radical levels in a preclinical F98 rat glioma model
Keywords: BSA; bovine serum albumin; CNS; central nervous system; ERK 1/2; extracellular signal-regulated kinase 1/2; DMPO; 5,5-dimethyl-1-pyrroline N-oxide; DTPA; diethylene triamine penta acetic acid; EGF; epidermal growth factor; Gd; gadolinium; HIF-1α; hypoxia
Binge alcohol promotes hypoxic liver injury through a CYP2E1-HIF-1α-dependent apoptosis pathway in mice and humans
Keywords: HIF-1α; hypoxia-inducible factor-1α; BAC; blood alcohol concentration; CYP2E1; cytochrome P450 2E1; ALD; alcoholic liver disease; NIAAA; National Institute on Alcohol Abuse and Alcoholism; iNOS; inducible nitric oxide synthase; ADH; alcohol dehydrogenas
The Janus face of the heme oxygenase/biliverdin reductase system in Alzheimer disease: It's time for reconciliation
Keywords: BVR-A; biliverdin reductase isoform A; HO-1/2; heme oxygenase isoform 1 or 2; HNE; 4-hydroxy-2-nonenal; PC; protein carbonyls; 3-NT; 3-nitrotyrosine; ARE; antioxidant responsive elements; Alzheimer disease; Aging; Biliverdin reductase; Heme oxygenase; Mil
Interferon-gamma induced cell death: Regulation and contributions of nitric oxide, cJun N-terminal kinase, reactive oxygen species and peroxynitrite
Keywords: AG; aminoguanidine; BrdU; bromodeoxyuridine; DAF2DA; 4, 5-diaminofluorescein diacetate; DCFDA; 2â², 7â²-dichlorofluorescin diacetate; DHR123; dihydrorhodamine 123; FeTPPS; 5,10,15,20-tetrakis(4-sulfonatophenyl) porphyrinato iron (III), chloride; FITC; f
Vitamin E is essential for Purkinje neuron integrity
Keywords: 3-NT; 3-nitrotyrosine; AD; Alzheimer's disease; ANOVA; analysis of variance; AVED; ataxia with vitamin E deficiency; CS; conditioned stimulus; NPC; Niemann Pick disease type C; SCA; spinocerebellar ataxia; TBARS; thiobarbituric acid reactive substances;