Keywords: اسید 4-فنیل بوتیریک; 4-PBA; 4-phenylbutyric acid; ARA; arachidonic acid; ATF6; activating transcription factor 6; BiP or Grp78; 78-kDa glucose regulated protein; COX; cyclooxygenase; CYP; cytochrome P450; DHA; docosahexaenoic acid; eIF2α; eukaryotic translation initiation fa
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Keywords: اسید 4-فنیل بوتیریک; Ac-H3; acetylated histone H3; Actb; β-actin; ALS; amyotrophic lateral sclerosis; BA; butyric acid; BA3G; glyceryl tributyrate; b.i.d.; bis in die; CNS; central nervous system; CREB; cAMP responsive element-binding protein; FL-SMN; full-length survival mo
Keywords: اسید 4-فنیل بوتیریک; 4-Phenylbutyric acid; 4-PBA; UPR; ER stress
Keywords: اسید 4-فنیل بوتیریک; CHOP; C/EBP homologous protein; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; DC; dendritic cell; PERK; double-stranded RNA-activated protein kinase-like ER kinase; ER; endoplasmic reticulum; eIF2α; eukaryotic translation initiation
Keywords: اسید 4-فنیل بوتیریک; 4-PBA; 4-phenylbutyric acid; CF; cardiac fibroblasts; ER; endoplasmic reticulum; FBS; fetal bovine serum; FCS; fetal calf serum; PBS; phosphate buffer saline; ROS; reactive oxygen species; UPR; unfolded protein response; Cardiac fibroblast; ER stress; Tha
Keywords: اسید 4-فنیل بوتیریک; Chronic renal failure; Endoplasmic reticulum stress; Atherosclerosis; 4-Phenylbutyric acid; Inflammatory activation
Keywords: اسید 4-فنیل بوتیریک; BMI; body mass index; CRP; C-reactive protein; db/db; diabetic; ER; endoplasmic reticulum; HSP; heat shock proteins; JAK; janus kinase; ob/ob; obese; LEPR; leptin receptor; MAPK; mitogen-activated protein kinase; mTOR; mammalian target of rapamycin; NK; n
Comparative hepatic transcriptome analyses revealed possible pathogenic mechanisms of fasiglifam (TAK-875)-induced acute liver injury in mice
Keywords: اسید 4-فنیل بوتیریک; Fasiglifam (TAK-875); Drug-induced liver injury (DILI); Microarray; Comparative hepatic transcriptome analysis; Gene set enrichment analysis; ALT; Alanine aminotransferase; Bsep; Bile salt export pump; CCl4; Carbon tetrachloride; ConA; Concanavalin A; DAM
β-elemene regulates endoplasmic reticulum stress to induce the apoptosis of NSCLC cells through PERK/IRE1α/ATF6 pathway
Keywords: اسید 4-فنیل بوتیریک; NSCLC; non-small-cell lung cancer; ER; endoplasmic reticulum; ERs; endoplasmic reticulum stress; 4-PBA; 4-phenylbutyric acid; WB; western blotting; q-PCR; quantitative reverse transcription polymerase chain reaction; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-
Original ArticleSensitivity towards the GRP78 inhibitor KP1339/IT-139 is characterized by apoptosis induction via caspase 8 upon disruption of ER homeostasis
Keywords: اسید 4-فنیل بوتیریک; Sodium trans-[tetrachlorobis(1H-indazole)ruthenate(III)]; Ruthenium; Extrinsic pathway of programmed cell death; GRP78; Caspase 8; 4-PBA; 4-phenylbutyric acid; CHOP; C/EBP-homologous protein; CI; combination index; CFTR; cystic fibrosis transmembrane cond
Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages
Keywords: اسید 4-فنیل بوتیریک; TFPI; Cholesterol crystals; ER stress; Macrophages; Carotid endarterectomies; Inflammation; CC; cholesterol crystals; CHOP; CCAAT/enhancer-binding protein homologous protein; ER; endoplasmic reticulum; MDMs; monocyte-derived macrophages; PBA; 4-phenylbuty
Antitumor platinum(IV) derivatives of carboplatin and the histone deacetylase inhibitor 4-phenylbutyric acid
Keywords: اسید 4-فنیل بوتیریک; Anticancer; Carboplatin; Histone deacetylase inhibitor; 4-Phenylbutyric acid; Platinum(IV);
Tetramethylpyrazine suppresses angiotensin II-induced soluble epoxide hydrolase expression in coronary endothelium via anti-ER stress mechanism
Keywords: اسید 4-فنیل بوتیریک; AUDA; 12-[[(tricyclo[3.3.1.13,7]dec-1ylamino)carbonyl]amino]dodecanoic acid; 4-PBA; 4-phenylbutyric acid; GRP78; 78-kDa glucose-regulated protein; ATF6; Activating transcription factor 6; Ang-II; Angiotensin-II; CYP; Cytochrome P450; ER stress; Endoplasmi
Nox4 regulates the eNOS uncoupling process in aging endothelial cells
Keywords: اسید 4-فنیل بوتیریک; eNOS; endothelial nitric oxide synthase; HUVEC; human umbilical vein endothelial cells; NO; nitric oxide; Nox4; NADPH oxidase 4; ROS; reactive oxygen species; NAC; N-acetyl cysteine; TUDCA; tauroursodeoxycholic acid; 4-PBA; 4-phenylbutyric acid; ER; endop
4-Phenylbutyric acid reduces mutant-TGFBIp levels and ER stress through activation of ERAD pathway in corneal fibroblasts of granular corneal dystrophy type 2
Keywords: اسید 4-فنیل بوتیریک; ER stress; UPR; ERAD; 4-Phenylbutyric acid; TGFBIp; GCD2; Corneal fibroblasts; 4-PBA; Sodium 4-phenylbutyric acid; ATF6; Activating transcription factor 6; BiP; Binding immunoglobulin protein; CHOP; C/EBP homologous protein; ER; Endoplasmic reticulum; ERA
Improvement of mTORC1-driven overproduction of apoB-containing triacylglyceride-rich lipoproteins by short-chain fatty acids, 4-phenylbutyric acid and (R)-α-lipoic acid, in human hepatocellular carcinoma cells
Keywords: اسید 4-فنیل بوتیریک; ACC; acetyl-CoA carboxylase; Akt; protein kinase B; AMPK; AMP-activated protein kinase; apoB; apolipoprotein B; apoE; apolipoprotein E; CPT1α; carnitine palmitoyltransferase 1α; DGAT1; diacylglycerol O-acyltransferase 1; DGAT2; diacylglycerol O-acyltran
Palmitic acid aggravates inflammation of pancreatic acinar cells by enhancing unfolded protein response induced CCAAT-enhancer-binding protein β-CCAAT-enhancer-binding protein α activation
Keywords: اسید 4-فنیل بوتیریک; AP; acute pancreatitis; ATF6; activating transcription factor 6; BSA; bovine serum albumin; CCK-8; cholecystokinin-8; C/EBP; CCAAT-enhancer-binding protein; CHOP; CCAAT/enhancer binding protein (C/EBP) homologous protein; eIF2; αeukaryotic translation in
Terpene glycoside component from Moutan Cortex ameliorates diabetic nephropathy by regulating endoplasmic reticulum stress-related inflammatory responses
Keywords: اسید 4-فنیل بوتیریک; TCM; traditional Chinese Medicine; MC; Moutan Cortex; TG; terpene glycoside; DN; diabetic nephropathy; STZ; streptozotocin; AGEs; advanced glycation end-products; ER; endoplasmic reticulum; 4-PBA; 4-phenylbutyric acid; AG; amino guanidine; TEM; transmissi
Buforin IIb induces endoplasmic reticulum stress-mediated apoptosis in HeLa cells
Keywords: اسید 4-فنیل بوتیریک; Buforin IIb; Anticancer peptide; Apotosis; ER stress; Mitochondrial membrane permeabilization; AMP; antimicrobial peptide; ER; endoplasmic reticulum; SAPK/JNK; stress-activated protein kinase/Jun-amino-terminal kinase; p38 MAPK; p38 mitogen-activated prot
Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing
Keywords: اسید 4-فنیل بوتیریک; AAD; active adenylation domain; 4-PBA; 4-phenylbutyric acid; 6-OHDA; 6-hydroxydopamine; ABCG5/8; ATP-binding cassette sub-family G member 5/8; AD; Alzheimer's disease; AIB1; amplified in breast cancer 1; AIP4; atrophin-1 interacting protein 4; AMPA; α-
Increased RANKL-mediated osteoclastogenesis by interleukin-1β and endoplasmic reticulum stress
Keywords: اسید 4-فنیل بوتیریک; Endoplasmic reticulum stress; IL-1β; Osteoclast; 4-phenylbutyric acid; Thapsigargin
Chemical chaperones reduce ionizing radiation-induced endoplasmic reticulum stress and cell death in IEC-6 cells
Keywords: اسید 4-فنیل بوتیریک; ER; endoplasmic reticulum; UPR; unfolded protein response; eIF2α; eukaryotic translation initiation factor 2α; ATF4; activating transcription factor 4; PERK; RNA-dependent-protein-kinase-like ER kinase; PBA; 4-phenylbutyric acid; siRNA; small interferin
Calumenin has a role in the alleviation of ER stress in neonatal rat cardiomyocytes
Keywords: اسید 4-فنیل بوتیریک; ATF; activating transcription factor; Ad-calu; adenovirus containing mouse calumenin 1 cDNA; Ad-lacZ; adenovirus containing lacZ gene; CHOP; C/EBP-homologous protein; ERAD; ER-associated degradation; eIF2; eukaryotic initiation factor 2; ERp57; the thiol
Glucotoxic conditions induce endoplasmic reticulum stress to cause caspase 3 mediated lamin B degradation in pancreatic β-cells: Protection by nifedipine
Keywords: اسید 4-فنیل بوتیریک; CHOP; C/EBP homologous protein; ER; endoplasmic reticulum; FTase; farnesyl transferase; FTI; farnesyl transferase inhibitor; Nif; nifedipine; PBA; 4-phenylbutyric acid; Tg; thapsigargin; Caspase 3; Glucotoxicity; Nuclear lamin B; Pancreatic islet β-cell;
Carbon monoxide, a reaction product of heme oxygenase-1, suppresses the expression of C-reactive protein by endoplasmic reticulum stress through modulation of the unfolded protein response
Keywords: اسید 4-فنیل بوتیریک; ATF6; activating transcription factor 6; CRP; C-reactive protein; CO; carbon monoxide; CORM-2; CO-releasing molecule-2 (tricarbonyl dichlororuthenium dimer); CORM-3; CO-releasing molecule-3 (tricarbonylchliro(glycinate)ruthenium); CREBH; cyclic AMP respon
HER2 Interacts With CD44 to Up-regulate CXCR4 via Epigenetic Silencing of microRNA-139 in Gastric Cancer Cells
Keywords: اسید 4-فنیل بوتیریک; Trastuzumab/Herceptin; Cancer Cell Signaling; Histone Deacetylase; Metastasis-Associated Protein-1; CXCR4; C-X-C chemokine receptor type 4; GSP; gene-specific primer; H3K9; the ninth lysine of histone H3; HDAC; histone deacetylase; HER2; human epidermal g
A chemical chaperone, sodium 4-phenylbutyric acid, attenuates the pathogenic potency in human α-synuclein A30P + A53T transgenic mice
Keywords: اسید 4-فنیل بوتیریک; Parkinson's disease; Alpha-synuclein; Chemical chaperone; 4-Phenylbutyric acid
Thermodynamics of the hydrolysis reactions of nitriles
Keywords: اسید 4-فنیل بوتیریک; Ammonia; Apparent equilibrium constant; Benzeneacetic acid; Benzoic acid; Benzonitrile; Benzylcyanide; Enthalpy; Entropy; Gibbs free energy; Indole-3-acetic acid; 3-Indoleacetonitrile; α-Methylbenzeneacetic acid; α-Methylbenzyl cyanide; 4-Phenylbutyonit
Cellular abnormalities linked to endoplasmic reticulum dysfunction in cerebrovascular disease-therapeutic potential
Keywords: اسید 4-فنیل بوتیریک; Degenerative diseases; Endoplasmic reticulum; Ischemia; Stroke; Unfolded protein response; 4-PBA; 4-phenylbutyric acid; Aβ; amyloidogenic β-peptide; ATF; activating transcription factor; eIF2α; alpha subunit of the eukaryotic initiation factor 2; ER; e