دانلود مقالات ISI درباره Aav + ترجمه فارسی

AAV2 production with optimized N/P ratio and PEI-mediated transfection results in low toxicity and high titer for in vitro and in vivo applications

Keywords: Recombinant virus; Optimization; AAV; AAV2-GFP; Polyethylenimine (PEI); N/P ratio;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Normalizing dopamine D2 receptor-mediated responses in D2 null mutant mice by virus-mediated receptor restoration: Comparing D2L and D2S

Keywords: AAV; adeno-associated virus; BSA; bovine serum albumin; D2L; D2 receptor long form; D2S; receptor short form; DARPP-32; Dopamine- and cyclic AMP-regulated phosphoprotein of about 32 kD; Drd2−/−; D2 receptor null mutant; Drd2ex6−/ex6−; D2L receptor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

AAV2-mediated striatum delivery of human CDNF prevents the deterioration of midbrain dopamine neurons in a 6-hydroxydopamine induced parkinsonian rat model

Keywords: CDNF; Parkinson's disease; AAV; 6-OHDA; PET;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Pathogenesis of growth failure and partial reversal with gene therapy in murine and canine Glycogen Storage Disease type Ia

Keywords: AAV; Adeno-associated virus; AAV-G6Pase; Adeno-associated viral vector expressing glucose-6-phosphatase; BCS; Body Condition Score; BMI; Body Mass Index; FASN; Fatty Acid Synthase; G6Pase; Glucose 6-phosphatase; GSD-Ia; Glycogen Storage Disease Ia; GH; Gr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Atomic modeling of cryo-electron microscopy reconstructions - Joint refinement of model and imaging parameters

Keywords: AAV; adeno associated virus; CDR; complementarity determiniming region; CTF; contrast transfer function; EM; electron microscopy; mAb; monoclonal antibody; Mm-cpn; Methanococcus marapaludis chaperonin; NCS; non crystallographic symmetry; RMS(D); root mean

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-κB signaling in dopaminergic cells

Keywords: 6-OHDA; 6-Hydroxydopamine; AAV; adeno-associated virus; AD; Alzheimer's disease; ANOVA; analysis of variance; AP; anteroposterior; BDNF; brain-derived neurotrophic factor; CD200; cluster of differentiation 200; DLB; dementia with Lewy bodies; DV; dorsoven

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Antineutrophil Cytoplasmic Antibody-Associated Renal Vasculitis Treated With Autologous Mesenchymal Stromal Cells: Evaluation of the Contribution of Immune-Mediated Mechanisms

Keywords: AAV; ANCA-associated vasculitis; ANCA; antineutrophil cytoplasmic antibody; BVAS; Birmingham Vasculitis Activity Score; CTL; cytotoxic T lymphocyte; CYC; cyclophosphamide; IL; interleukin; MSC; mesenchymal stromal cell; NK; natural killer; pANCA; ANCA wit

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Gene therapy and neurodevelopmental disorders

Keywords: Gene therapy; AAV; Neurodevelopmental disorder; Rett syndrome; Angelman syndrome; Lysosomal storage disease

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

RNAi or overexpression: Alternative therapies for Spinocerebellar Ataxia Type 1

Keywords: Spinocerebellar Ataxia Type 1; Ataxin-1; Ataxin-1-like; miRNA; RNAi; AAV; Cerebellum; Neurodegeneration; Polyglutamine

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Neuropeptides in epilepsy

Keywords: Neuropeptide Y; Ghrelin; Galanin; Somatostatin; Substance P; Tachykinin; Dynorphin; Epilepsy; Seizures; Viral vector; AAV

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Transgenic overexpression of the cell adhesion molecule L1 in neurons facilitates recovery after mouse spinal cord injury

Keywords: AAV; adeno-associated virus; CNS; central nervous system; ChAT; choline acetyl transferase; GFAP; glial fibrillary acidic protein; PBS; phosphate-buffered saline pH 7.3; RT; room temperature; SCI; spinal cord injury; Thy-1; thymocyte differentiation antig

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Nuclear α1-Antichymotrypsin Promotes Chromatin Condensation and Inhibits Proliferation of Human Hepatocellular Carcinoma Cells

Keywords: Liver Cancer; Nuclear Factor; Mouse Model; DNA Binding; AAV; adeno-associated virus; α1-ACT; antichymotrypsin; APP; acute-phase protein; APR; acute-phase response; DOX; doxycycline; EGF; epidermal growth factor; HCC; hepatocellular carcinoma; MENT; myelo

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Clinical applications of retinal gene therapy

Keywords: Adeno-associated virus; Gene therapy; Clinical trial; LCA; AAV; RP; NV-AMD

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2013 سفارش ترجمه

AAV micro-dystrophin gene therapy alleviates stress-induced cardiac death but not myocardial fibrosis in > 21-m-old mdx mice, an end-stage model of Duchenne muscular dystrophy cardiomyopathy

Keywords: Dilated cardiomyopathy; Heart failure; Gene therapy; Duchenne muscular dystrophy; Dystrophin; AAV; Duchenne cardiomyopathy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

In vitro cell subtype-specific transduction of adeno-associated virus in mouse and marmoset retinal explant culture

Keywords: AAV; Retina; Mouse; Marmoset;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Ezetimibe: A biomarker for efficacy of liver directed UGT1A1 gene therapy for inherited hyperbilirubinemia

Keywords: UCB; unconjugated bilirubin; BMG; bilirubin mono-glucuronide; BDG; bilirubin di-glucuronide; AAV; adeno‐associated virus; scAAV; self complementary AAV; CNI; Crigler-Najjar syndrome type I; CN II; Crigler-Najjar syndrome type II; UGT1A1; uridine 5'-di-p

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Guided delivery of adeno-associated viral vectors into the primate brain

Keywords: Gene delivery; AAV; Non-human primate; MRI-guided delivery; Thalamus; Basal ganglia

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Developing treatment options for metachromatic leukodystrophy

Keywords: ARSA; arylsulfatase A; LSD; lysosomal storage disease; MLD; metachromatic leukodystrophy; HSCT; hematopoietic stem cell transplantation; UCBT; umbilical cord blood transplantation; MSCT; mesenchymal stem cell transplantation; ERT; enzyme replacement thera

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Adult-onset focal expression of mutated human tau in the hippocampus impairs spatial working memory of rats

Keywords: AAV; Hippocampus; Learning; Memory; P301L; Tauopathy;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Original articleNovel AAV-based genetic vaccines encoding truncated dengue virus envelope proteins elicit humoral immune responses in mice

Keywords: Dengue virus; Envelope; AAV; Genetic vaccine;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Neurodegeneration, Neuroprotection, and Disease-Oriented NeuroscienceResearch PaperDevelopment and characterisation of a novel rat model of Parkinson's disease induced by sequential intranigral administration of AAV-α-synuclein and the pesticide, rotenon

Keywords: Parkinson's disease; animal models; AAV-α-synuclein; rotenone; motor function; AAV; adeno-associated virus;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Comparison of the behavioural and histological characteristics of the 6-OHDA and α-synuclein rat models of Parkinson's disease

Keywords: Behavioural test; Neurodegeneration; Axonopathy; AAV; Animal models;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Research ReportEffects of A-CREB, a dominant negative inhibitor of CREB, on the expression of c-fos and other immediate early genes in the rat SON during hyperosmotic stimulation in vivo

Keywords: C-FOS; CREB; A-CREB; AAV; SON; Vasopressin;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

BDNF: The career of a multifaceted neurotrophin in spinal cord injury

Keywords: AAV; adeno-associated virus; BDNF; brain-derived neurotrophic factor; CST; corticospinal tract; KCC2; potassium-chloride transporter; L; lumbar level; NT; neurotrophin; T; thoracic level; TrkB; tropomyosin-related kinase B; TrkB signaling; Neuroprotection

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Gene therapy in the Cornea: 2005-present

Keywords: Cornea; Gene therapy; AAV; Nanoparticles; Decorin; Corneal scarring; Corneal neovascularization;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2012 سفارش ترجمه

Translating the therapeutic potential of neurotrophic factors to clinical ‘proof of concept’: A personal saga achieving a career-long quest

Keywords: Translational research; Neurotrophic factor; Gene transfer; Gene therapy; Parkinson's disease; Neurturin; AAV; CERE-120; Therapeutic development; Proof of concept

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2012 سفارش ترجمه

From oxygen to erythropoietin: Relevance of hypoxia for retinal development, health and disease

Keywords: Oxygen; Hypoxia; Retina; HIF; Retinal vasculature; Preconditioning; EPO; Retinal development; Degeneration; Neuroprotection; VEGF; Angiogenesis; Neovascularization; A(2A)R; adenosine A(2A) receptor; AAV; adeno-associated virus; Adm; adrenomedullin; AGE; a

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2012 سفارش ترجمه

Age and α-synuclein expression interact to reveal a dependence of dopaminergic axons on endogenous Akt/PKB signaling

Keywords: AAV; adeno-associated virus; DAB; diaminobenzidine-HCl; DN; dominant negative; GDNF; glial cell line-derived neurotrophic factor; GFAP; glial fibrillary acidic protein; PB; phosphate buffer; PBS; phosphate-buffered saline; PD; Parkinson's disease; PH; ple

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Viral vector tropism for supporting cells in the developing murine cochlea

Keywords: AAV; adeno-associated virus; ABR; auditory brainstem response; ADNSHL; autosomal dominant nonsyndromic hearing loss; ARNSHL; autosomal recessive nonsyndromic hearing loss; AV; adenovirus; BAAV; bovine adeno-associated virus; CMV; cytomegalovirus; CX26; co

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Cochlear infrastructure for electrical hearing

Keywords: AAV; adeno-associated viral vector; BDNF; brain-derived neurotrophic factor; C level; maximum comfortable loudness level; CU; current units; DR; dynamic range; EABR; electrically-evoked auditory brainstem response; ECAP; electrically-evoked compound actio

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Research ArticleAdipose tissue-derived mesenchymal stem cell-based liver gene delivery

Keywords: Alpha 1 antitrypsin deficiency; Adeno-associated virus (AAV); Liver gene therapy; Liver regeneration; AT-MSCs; adipose tissue-derived mesenchymal stem cells; AAT; alpha 1-antitrypsin; AAV; adeno-associated virus;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Inverse zonation of hepatocyte transduction with AAV vectors between mice and non-human primates

Keywords: Gene therapy; AAV; Liver; Animal models;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Cellular fusion for gene delivery to SCA1 affected Purkinje neurons

Keywords: Spinocerebellar Ataxia 1; Bone marrow-derived cells; Hematopoietic stem cells; Gene therapy; AAV; Stem cell fusion

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Vaccine protection against lethal homologous and heterologous challenge using recombinant AAV vectors expressing codon-optimized genes from pandemic swine origin influenza virus (SOIV)

Keywords: AAV; Influenza; Vaccine; SOIV; H1N1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Constitutive and LPS-regulated expression of interleukin-18 receptor beta variants in the mouse brain

Keywords: Interleukin-18; Lipopolysaccharide; Brain; Mouse; IL-18Rβ; Splice variant; 3V; third ventricle; 7; facial nucleus; AAD; anterior amygdaloid area dorsal part; AAV; anterior amygdaloid area ventral part; Acb; nucleus accumbens; ACo; cortical amygdaloid nuc

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Direct gene transfer to the CNS prevents emergence of neurologic disease in a murine model of mucopolysaccharidosis type I

Keywords: Mucopolysaccharidosis; Hurler syndrome; Lysosomal storage disease; Iduronidase; AAV; Gene transfer; Intracerebroventricular; Water maze;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Inflammation Promotes the Loss of Adeno-Associated Virus-Mediated Transgene Expression in Mouse Liver

Keywords: Hepatic Gene Therapy; Loss of Tolerance; Immune Response; Liver Inflammation; AAT; α1-antitrypsin; AAV; adeno-associated vector; Ad; adenovirus vector; β-gal; β-galactosidase; CTL; cytotoxic T lymphocyte; GFP; green fluorescent protein; IFN; interferon

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Latest developments in the large-scale production of adeno-associated virus vectors in insect cells toward the treatment of neuromuscular diseases

Keywords: AAV; Baculovirus expression system; Gene therapy; Neuromuscular diseases; Large-scale vector production

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

The role of NPY in hypothalamic mediated food intake

Keywords: 2-AG; 2-arachidonoylglycerol; AAV; adeno associated virus; AEA; N-arachidonoylethanolamide/anandamide; AgRP; agouti-related peptide; α-MSH; alpha melanocyte stimulating hormone; ARC; arcuate nucleus; BBB; blood-brain barrier; CART; cocaine and amphetam

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2011 سفارش ترجمه

Triptolide T10 enhances AAV-mediated gene transfer in mice striatum

Keywords: Triptolide; AAV; Gene therapy; Parkinson's disease

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

A pseudo-plaque method for infectious particle assay and clonal isolation of adeno-associated virus

Keywords: AAV; adeno-associated virus; Ad; adenovirus; ELISA; enzyme-linked immunosorbent assay; MAb; monoclonal antibody; NBT; nitro blue tetrazolium; MTT; (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PBS; phosphate buffered saline; PCR; polymera

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Adeno-associated viral vector (AAV)-mediated gene transfer in the red nucleus of the adult rat brain: Comparative analysis of the transduction properties of seven AAV serotypes and lentiviral vectors

Keywords: AAV; CNS; Gene therapy; Nucleus ruber; Rubrospinal tract; Transduction

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Ultrasound Microbubbles Enhance Recombinant Adeno-Associated Virus Vector Delivery to Retinal Ganglion Cells In Vivo

Keywords: Ultrasound microbubble; AAV; retinal ganglion cells; gene transfer; in vivo; enhanced green fluorescent protein;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Increasing cholesterol synthesis in 7-dehydrosterol reductase (DHCR7) deficient mouse models through gene transfer

Keywords: DHC, dehydrocholesterol; C, cholesterol; DHCR7, 7-dehydrocholesterol reductase; AAV, adeno-associated virus; BSTFA, N,O-bis[trimethylsilyl]trifluoroacetamide; TMS, trimethylsilylSmith–Lemli–Opitz syndrome (SLOS); DHCR7; AAV; Gene therapy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Sites in the AAV5 capsid tolerant to deletions and tandem duplications

Keywords: Directed evolution; AAV; Viral gene delivery;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Vasculitis in children

Keywords: AAV; ANCA; children; Churg-Strauss syndrome; Henoch-Schönlein purpura; Kawasaki disease; microscopic polyangiitis; paediatric; polyarteritis nodosa; Takayasu arteritis; vasculitis; Wegener's granulomatosis

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Transduction of the inner mouse retina using AAVrh8 and AAVrh10 via intravitreal injection

Keywords: adeno-associated virus; AAV; inner retina; inner nuclear layer; horizontal cells; retina; retinal gene deliveryAAV, adeno-associated virus; EGFP, enhanced green fluorescent protein; gc, genome copies; GCL, ganglion cell layer; GFAP, glial fibrillary acidi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Cardiomyocyte-targeted HIF-1α gene therapy inhibits cardiomyocyte apoptosis and cardiac allograft vasculopathy in the rat

Keywords: AAV; apoptosis; CAV; HIF-1α; ischemia;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Analysis of angiogenesis induced by local IGF-1 expression after myocardial infarction using microSPECT-CT imaging

Keywords: AAV; IGF-1; Angiogenesis; MicroSPECT-CT; Molecular imaging; Myocardial infarction;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Widespread cortical expression of MANF by AAV serotype 7: Localization and protection against ischemic brain injury

Keywords: Gene therapy; Stroke; AAV; MANF; Neurotrophic factor; Mesencephalic astrocyte-derived neurotrophic factor; ARMET; CDNF

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه