دانلود مقالات ISI درباره Aav + ترجمه فارسی

ReviewGene therapy for Parkinson's disease: Disease modification by GDNF family of ligands

Keywords: Adeno-associated virus; AAV; Viral vectors; Non-human primates; GDNF; Neurturin; Neurotrophic factors; Dopamine;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Research PaperVentral medullary control of rapid eye movement sleep and atonia

Keywords: REM arousal; GABA; VGAT; DREADD; AAV;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Catecholaminergic A1/C1 neurons contribute to the maintenance of upper airway muscle tone but may not participate in NREM sleep-related depression of these muscles

Keywords: Obstructive sleep apnea; Sleep; hM4Di receptors; AAV; Genioglossus; DREADD; EEG;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Long-term oral kinetin does not protect against α-synuclein-induced neurodegeneration in rodent models of Parkinson's disease

Keywords: PINK1; α-Synuclein; Kinetin; Neurodegeneration; Parkinson's disease; Adeno-associated virus; AAV;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Optogenetic Modulation of Cardiac Sympathetic Nerve Activity to Prevent Ventricular Arrhythmias

Keywords: left stellate ganglion neural silencing; optogenetics; ventricular arrhythmia; AAV; adeno-associated virus; APD; action potential duration; APD90; 90% repolarization duration; BP; blood pressure; ECG; electrocardiography; ERP; effective refractory period;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Research PaperLong-term protective effects of AAV9-mesencephalic astrocyte-derived neurotrophic factor gene transfer in parkinsonian rats

Keywords: 6-OHDA; 6-hydroxydopamine; AAV; adeno-associated virus; ATF4; activating transcription factor 4; ATF6α; activating transcription factor 6α; Bip; binding immunoglobulin protein; CDNF; cerebral dopamine neurotrophic factor; CR3; complement receptor 3; CHO

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Near-infrared fluorescent protein iRFP713 as a reporter protein for optogenetic vectors, a transgenic Cre-reporter rat, and other neuronal studies

Keywords: iRFP713; Near infrared; Transgene; AAV; Optogenetics;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Pulmonary ORMDL3 is critical for induction of Alternaria-induced allergic airways disease

Keywords: ORMDL3; asthma; unfolded protein response; uric acid; Alternaria; AAD; Allergic airways disease; AAV; Adeno-associated viral vector; AHR; Airway hyperreactivity; ATF; Activating transcription factor; BALF; Bronchoalveolar lavage fluid; EGFP; Enhanced gree

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Exosomes: Therapy delivery tools and biomarkers of diseases

Keywords: AAV; adeno-associated virus; APC; antigen-presenting cell; CNS; central nervous system; CSF; cerebrospinal fluid; DC; dendritic cell; EBV; Epstein-Barr virus; EGFR; epidermal growth factor receptor; EEF; eukaryotic elongation factors; ESCRT; endosomal-sor

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleAAV-mediated pancreatic overexpression of Igf1 counteracts progression to autoimmune diabetes in mice

Keywords: Autoimmune diabetes; NOD; IGF1; Pancreas; AAV;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Self-assembled amphiphilic core-shell nanocarriers in line with the modern strategies for brain delivery

Keywords: Brain targeting; Core-shell nanocarriers; Micelles; Nanotechnology; 17-AAG; 17-Allylamino-17-demethoxy geldanamycin; 5-FU; 5-flourouracil; AAV; adeno-associated virus; ABC; ATP binding cassette; Ach; acetyl choline; AFM; atomic force microscopy; AmB; amph

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Mesencephalic astrocyte-derived neurotrophic factor (MANF), a new player in endoplasmic reticulum diseases: structure, biology, and therapeutic roles

Keywords: AAV; adeno-associated virus; AKI; acute kidney injury; ARMET; arginine-rich mutated in early tumors; ATF6; activating transcription factor 6; BiP; Ig-binding protein; CDNF; conserved dopamine neurotrophic factor; CHOP; C/EBP homologous protein; DM; diabet

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Insulin-dependent metabolic and inotropic responses in the heart are modulated by hydrogen peroxide from NADPH-oxidase isoforms NOX2 and NOX4

Keywords: ROS; Reactive oxygen species; PKA; Protein kinase A; NOX; NADPH oxidase; PTP1B; Protein tyrosine phosphatase 1B; CaMK; Calmodulin Kinase; mTOR; Mammalian target of rapamycin; AAV; Adeno-associated virus; CIRKO; Cardiac insulin receptor knockout; IGF-1; In

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

AAV-mediated gene delivery attenuates neuroinflammation in feline Sandhoff disease

Keywords: AAV; adeno-associated virus; CNS; central nervous system; DCN; deep cerebellar nuclei; GFAP; glial fibrillary acidic protein; Hex; β-N-acetylhexosaminidase; Iba1; ionized calcium-binding protein 1; ICV; intracerebroventricular; IL-1β; interleukin 1 beta

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Slow Intrathecal Injection of rAAVrh10 Enhances its Transduction of Spinal Cord and Therapeutic Efficacy in a Mutant SOD1 Model of ALS

Keywords: ALS; amyotrophic lateral sclerosis; IT; intrathecal; rAAV; recombinant adeno-associated virus; CNS; central nervous system; DRG; dorsal root ganglia; IV; intravenous; qPCR; quantitative Polymerase Chain Reaction; DH; dorsal horn; PF; posterior funiculus;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

A directed evolution approach to select for novel Adeno-associated virus capsids on an HIV-1 producer T cell line

Keywords: Directed evolution; AAV; Gene transfer; T cell; HIV-1;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Distinct roles of neuronal and microglial CB2 cannabinoid receptors in the mouse hippocampus

Keywords: AAV; adeno-associate virus; AP; anterior posterior; CaMKII; calcium/calmodulin-dependent protein kinase II; Cas9; CRISPR-associated protein 9; CB1R; type-1 cannabinoid receptor; CB2R; type-2 cannabinoid receptor; CNS; central nervous system; CRISPR; clust

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

In vivo genome editing as a potential treatment strategy for inherited retinal dystrophies

Keywords: Genome editing; In vivo; Retina; CRISPR-Cas; TALEN; AAV; Endonucleases; NHEJ; HDR; MMEJ;

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

A new HDV mouse model identifies mitochondrial antiviral signaling protein (MAVS) as a key player in IFN-β induction

Keywords: Hepatitis delta virus; Hepatitis B virus; HDV/HBV co-infection; Mouse model; AAV; Liver injury; Innate immune response;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Targeting chaperones, heat shock factor-1, and unfolded protein response: Promising therapeutic approaches for neurodegenerative disorders

Keywords: 17-AAG; 17-(allylamino)-17-demethoxygeldanamycin (tanespimycin); 17-DMAG; 17- dimethylaminoethylamino-17-demethoxygeldanamycin (alvespimycin); AAV; adeno-associated virus; Aβ; amyloid-β; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP;

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2017 سفارش ترجمه

Preferred transduction with AAV8 and AAV9 via thalamic administration in the MPS IIIB model: A comparison of four rAAV serotypes

Keywords: MPS IIIB; Mucopolysaccharidosis type III B; Gene therapy; Adeno-associated virus; AAV; Lysosomal storage diseaserAAV, recombinant adeno-associated virus; ANOVA, analysis of variance; MPS IIIB, mucopolysaccharidosis type III B; CNS, central nervous system;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Intramuscular administration of AAV overcomes pre-existing neutralizing antibodies in rhesus macaques

Keywords: AAV; adeno-associated viral; AAT; alpha-1-antitrypsin; CMV; cytomegalovirus; CTL; cytotoxic T lymphocyte; ELISA; enzyme-linked immunosorbent assay; ffLuc; firefly luciferase; GC; genome copies; HIV; human immunodeficiency virus; IA; immunoadhesin; IM; int

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Neonatal tolerance induction enables accurate evaluation of gene therapy for MPS I in a canine model

Keywords: AAV; Gene therapy; Intrathecal; MPS I; Neonatal tolerance;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

ReviewThe extreme N-terminus of TDP-43 mediates the cytoplasmic aggregation of TDP-43 and associated toxicity in vivo

Keywords: TDP-43; Aggregation; The extreme N-terminus; Toxicity; In vivo; AAV;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Genetics and pathophysiology of granulomatosis with polyangiitis (GPA) and its main autoantigen proteinase 3

Keywords: Granulomatosis with polyangiitis; GPA; Vasculitis; Neutrophils; Vascular diseases; ANCA-associated vasculitis; AAV; Proteinase 3;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

CaMKIIα knockdown decreases anxiety in the open field and low serotonin-induced upregulation of GluA1 in the basolateral amygdala

Keywords: 5-HT; AAV; amygdala; CaMKII; Glutamate; Immunoblot; RNAi; RT-PCR

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Long term study of deoxyribozyme administration to XT-1 mRNA promotes corticospinal tract regeneration and improves behavioral outcome after spinal cord injury

Keywords: 5-HT; 5-hydroxytryptamine; ANOVA; analysis of variance; as; antisense; AAV; adeno-associated virus; BBB; Basso, Beattie, Bresnahan; BDA; biotinylated dextran amine; BSA; bovine serum albumin; C; Celsius; cDNA; complementary deoxyribonucleic acid; CGRP; ca

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

The role of monocytes in ANCA-associated vasculitides

Keywords: AAV; Monocytes; Tissue damage; Granuloma; Autoimmunity; Therapeutic target;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

BDNF - a key transducer of antidepressant effects

Keywords: Brain-derived neurotrophic factor; Hippocampus; Synaptic plasticity; Behavior; Depression; AAV; adeno-associated virus; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; BDNF; brain derived neurotrophic factor; CA1; cornu ammonis area 1; CA3; c

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Peroxisome biogenesis disorders in the Zellweger spectrum: An overview of current diagnosis, clinical manifestations, and treatment guidelines

Keywords: AAV; adeno-associated virus; AED; anti-epileptic drug(s); DHA; docosahexaenoic acid; DHCA; dihydroxycholestanoic acid; ERG; electroretinogram; G-tube; gastrostomy tube; IRD; infantile Refsum disease; LC-MS/MS; liquid chromatography/tandem mass spectrometr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

AAV viral vector delivery to the brain by shape-conforming MR-guided infusions

Keywords: 16-G; 16-gauge; 3D; three-dimensional; 6-OHDA; 6-hydroxydopamine; AAV; adeno-associated virus; AD; Alzheimer's disease; CED; convection enhanced delivery; cGMP; current Good Manufacturing Practice; CN; caudate nucleus; CNS; central nervous system; CsCl; c

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

MicroRNAs in brain cholesterol metabolism and their implications for Alzheimer's disease

Keywords: AAV; adeno associated virus; ABC; ATP-binding cassette; ABCA1; ABC transporter A1; AD; Alzheimer's disease; APOA-I; apolipoprotein A1; APOE; apolipoprotein E; APP; amyloid β precursor protein; BBB; blood-brain barrier; CE; cholesteryl ester; CETP; chol

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

AAV-IL-22 modifies liver chemokine activity and ameliorates portal inflammation in murine autoimmune cholangitis

Keywords: IL-22; Liver autoimmune disease; Adeno-associated virus; Chemokine; Therapy; 2-OA-OVA; 2-octynoic acid conjugated ovalbumin; AAV; adeno-associated virus; AMAs; anti-mitochondrial antibodies; MNCs; mononuclear cells; PBC; primary biliary cholangitis; TU; t

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Pulmonary administration of small interfering RNA: The route to go?

Keywords: AAV; adeno-associated virus; Ago; Argonaute (protein family); AKT1; serine-threonine protein kinase; APC; antigen-presenting cell; AV; adenovirus; BALF; broncho-alveolar lavage fluid; COPD; chronic obstructive pulmonary disease; DC; dendritic cell; DOE; d

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Mineralocorticoid and angiotensin II type 1 receptors in the subfornical organ mediate angiotensin II - induced hypothalamic reactive oxygen species and hypertension

Keywords: AAV; adeno-associated virus; AAV-siRNA; adeno-associated virus carrying small interfering RNA; aldo; aldosterone; Ang II; angiotensin II; AS; aldosterone synthase; AT1R; angiotensin II type 1 receptor; BP; blood pressure; CNS; central nervous system; DEPC

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Adeno-associated virus gene therapy vector scAAVIGF-I for transduction of equine articular chondrocytes and RNA-seq analysis

Keywords: AAV; IGF-I; Gene therapy; Joint; Equine; NextGen sequencing;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Gene Therapy for Leber Hereditary Optic Neuropathy

Keywords: AAV; adeno-associated virus vector; ACF; anterior chamber fluid; DMEM; Dulbecco's modified Eagle's medium; ETDRS; Early Treatment Diabetic Retinopathy Study; IOP; intraocular pressure; LHON; Leber hereditary optic neuropathy; mtDNA; mitochondrial DNA; NAb

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Matricellular Protein CCN5 Reverses Established Cardiac Fibrosis

Keywords: apoptosis; gene therapy; heart failure; NFκB; AAV; adeno-associated virus; CF; cardiac fibrosis; EndMT; endothelial-mesenchymal transition; FACS; fluorescence-activated cell sorting; HCAEC; human coronary artery endothelial cell; HF; heart failure; LV; l

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Cardiac involvement in patients with rheumatic disorders: Data of the RHEU-M(A)R study

Keywords: AAV; ANCA-associated vasculitides; ANCA; Anti-neutrophil cytoplasmatic antibody; BVAS; Birmingham Vasculitis Activity Score; CAD; Coronary artery disease; CVD; Cardiovascular disease; CMR; Cardiovascular magnetic resonance; ECG; Electrocardiogram; EGPA; E

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Results at 2 Years after Gene Therapy for RPE65-Deficient Leber Congenital Amaurosis and Severe Early-Childhood-Onset Retinal Dystrophy

Keywords: AAV; adeno-associated virus; BCVA; best-corrected visual acuity; dB-sr; decibel-steradian; ETDRS; Early Treatment Diabetic Retinopathy Study; ERG; electroretinogram; LCA; Leber congenital amaurosis; logMAR; logarithm of the minimum angle of resolution; O

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Intratracheal Gene Delivery of SERCA2a Ameliorates Chronic Post-Capillary Pulmonary Hypertension: A Large Animal Model

Keywords: aerosol delivery; gene therapy; pig models; pulmonary vascular remodeling; right ventricular function; AAV; adeno-associated virus; AAV1.SERCA2a; recombinant adeno-associated virus serotype 1 carrying the human SERCA2a transgene; IQR; interquartile range;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Adeno-associated virus (AAV) vectors in cancer gene therapy

Keywords: Gene therapy; Gene delivery; Adeno-associated virus; AAV; Gene delivery vectors; Cancer;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

ReviewProbing pain pathways with light

Keywords: AAV; Adeno associated virus; AM; acetoxymethyl ester; CARS; coherent anti-Stokes Raman scattering; ChR2; channelrhodopsin-2; FP; fluorescent protein; FRET; Förster resonance energy transfer; GECIs; genetically-encoded Ca2+ indicators; GEVIs; genetically-

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2016 سفارش ترجمه

Successful disabling of the 5′ UTR of HCV using adeno-associated viral vectors to deliver modular multimeric primary microRNA mimics

Keywords: HCV; RNA interference; AAV; Gene therapy; Pri-miRNA mimics;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

Heat shock proteins in the retina: Focus on HSP70 and alpha crystallins in ganglion cell survival

Keywords: Heat shock protein; Retina; Ganglion cells; Optic nerve; Glaucoma; Neuroprotection; 17-AAG; 17-allylamino-17-demethoxygeldanamycin; AAV; adeno-associated virus; AD; Alzheimer's disease; Aβ; amyloid-β; ER; endoplasmic reticulum; GCL; ganglion cell layer;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

Span poly-L-arginine nanoparticles are efficient non-viral vectors for PRPF31 gene delivery: An approach of gene therapy to treat retinitis pigmentosa

Keywords: Nanoparticle; Span; Gene therapy; Ophthalmology; Retinitis pigmentosa; AAV; adeno-associated viral; AAV2; adeno-associated viral vectors serotype 2; adRP; autosomal dominant retinitis pigmentosa; ANOVA; analysis of variance; c/d; cycles/degree; DAPI; 4′

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2016 سفارش ترجمه

Mutant SOD1 mediated pathogenesis of Amyotrophic Lateral Sclerosis

Keywords: AAV; Adeno-associated viruses; ATP; Adenosine Triphosphate; ALS-FTD; ALS combined with frontotemporal dementia; ALS; Amyotrophic lateral sclerosis; ALSoD; Amyotrophic lateral sclerosis online database; C9orf72; Chromosome 9 open reading frame 72; ERGIC; E

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Glia-neuron interactions in the mammalian retina

Keywords: Retina; Neurons; Glial cells; Astrocytes; Müller glia; Microglia; Macrophages; Retinal ganglion cells; Photoreceptors; Glaucoma; Retinitis pigmentosa; Neuroprotection; Neurotrophins; Plasticity; Integrins; Extracellular matrix; AAV; adeno-associated viru

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2016 سفارش ترجمه

Autophagy in the eye: Development, degeneration, and aging

Keywords: Autophagy; Retina; Chaperone mediated autophagy; Lysosomes; Mitophagy; Retinal ganglion cells; Retinal pigment epithelial cells; Photoreceptor; Glaucoma; Macular degeneration; Retinal dystrophies; Diabetic retinopathy; 3-MA; 3-methyl adenine; 8-OH DPAT; 8

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2016 سفارش ترجمه

Optogenetic activation of striatal cholinergic interneurons regulates L-dopa-induced dyskinesias

Keywords: AAV; adeno-associated virus; ACh; acetylcholine; AIMs; abnormal involuntary movements; ANOVA; analysis of variance; LIDs; L-dopa-induced dyskinesias; ChAT; choline acetyltransferase; ChR2; channel rhodopsin 2; DAT; dopamine transporter; ERK; extracellular

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2016 سفارش ترجمه