Myocardial infarction in a 36-year-old man with combined ABCA1 and APOA-1 deficiency
Keywords: HDL cholesterol; Reverse cholesterol transport; Genetics; ABCA1; APOA1;
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Methyl protodioscin increases ABCA1 expression and cholesterol efflux while inhibiting gene expressions for synthesis of cholesterol and triglycerides by suppressing SREBP transcription and microRNA 33a/b levels
Keywords: Methyl protodioscin; HDL; LDL; ABCA1; SREBP; miR-33a/b;
RIP140 triggers foam-cell formation by repressing ABCA1/G1 expression and cholesterol efflux via liver X receptor
Keywords: ABCA1; ATP-binding cassette transporter A1; ABCG1; ATP-binding cassette transporter G1; apoA-I; apolipoprotein A-I; CD36; cluster of differentiation 36; ERR; estrogen receptor-related receptor; HDL; high-density lipoprotein; LXR; liver X receptor; LXRE; l
Whole exome sequencing combined with integrated variant annotation prediction identifies asymptomatic Tangier disease with compound heterozygous mutations in ABCA1 gene
Keywords: Tangier disease; ABCA1; HDL; Exome; Genetics;
Propofol up-regulates expression of ABCA1, ABCG1, and SR-B1 through the PPARγ/LXRα signaling pathway in THP-1 macrophage-derived foam cells
Keywords: Propofol; ABCA1; Cholesterol efflux; Macrophage; PPARγ/LXRα signaling pathway
Liver X Receptor (LXR) partial agonists: Biaryl pyrazoles and imidazoles displaying a preference for LXRβ
Keywords: SWBBNSPWRVCYAE-UHFFFAOYSA-N; WZMZHHPXANSLBG-UHFFFAOYSA-N; KMTFPMRUPSWRTQ-UHFFFAOYSA-N; DIRKHQVAVLSYMA-UHFFFAOYSA-N; XQWURCYLMCTAFE-UHFFFAOYSA-N; STNGIHCHDLCYEV-UHFFFAOYSA-N; VOOZJAGZCXOELE-UHFFFAOYSA-N; ZXTOKWKHXXGVMT-UHFFFAOYSA-N; SALZQMSOIKCKNM-UHFFFAOY
Regulation of retinoid mediated cholesterol efflux involves liver X receptor activation in mouse macrophages
Keywords: Retinoids; LXR; ABCA1; StAR; HSL; Cholesterol efflux; Macrophages;
Direct intracerebral delivery of a miR-33 antisense oligonucelotide into mouse brain increases brain ABCA1 expression
Keywords: ABCA1; Alzheimer’s disease; Antisense oligonucleotides; Intracerebral infusion; MicroRNA-33
Fenofibrate and extended-release niacin improve the endothelial protective effects of HDL in patients with metabolic syndrome
Keywords: ABCA1; ATP-binding cassette A1; ABCG1; ATP-binding cassette G1; CEC; cholesterol efflux capacity; CER; cholesterol esterification rate; CETP; cholesteryl ester transfer protein; CETR; cholesteryl ester transfer rate; CHD; coronary heart disease; eNOS; end
miR-28-5p Involved in LXR-ABCA1 Pathway is Increased in the Plasma of Unstable Angina Patients
Keywords: miR-28-5p; Unstable angina; ABCA1; LXRα; Circulation;
Asymptomatic individuals with high HDL-C levels overexpress ABCA1 and ABCG1 and present miR-33a dysregulation in peripheral blood mononuclear cells
Keywords: ABCA1; ATP binding cassete transporter A1; ABCG1; ATP binding cassete transporter G1; ANCOVA; analysis of covariance; ANOVA; analysis of variance; Apo A-I; apolipoprotein A-I; Apo B; apolipoprotein B; BAI; body adiposity index; BMI; body mass index; cDNA;
Genetic variants in ABCA1 promoter affect transcription activity and plasma HDL level in pigs
Keywords: ABCA1; ATP-binding cassette protein A1; HDL; plasma high density lipoprotein; RCT; reverse cholesterol transport; SNP; single nucleotide polymorphism; apoA-I; apolipoprotein A-I; LXRs; Liver X Receptors; RXRs; Retinoic X Receptors; PPAR; peroxisome prolif
PPAR-β/δ activation promotes phospholipid transfer protein expression
Keywords: apoA-I; ABCA1; HDL; Mice; Phospholipid transfer protein; PPAR-β/δ
RIP140 contributes to foam cell formation and atherosclerosis by regulating cholesterol homeostasis in macrophages
Keywords: LDL; low density lipoprotein; HDL; high density lipoprotein; RIP140; receptor interacting protein 140; ABCA1; ATP-binding membrane cassette transporter A-1; ABCG1; ATP-binding membrane cassette transporter G-1; RCT; reverse cholesterol transport; oxLDL; o
Transcriptomic profiling of male European eel (Anguilla anguilla) livers at sexual maturity
Keywords: ACAT1; acetyl-coenzyme A acetyltransferase 1-like; ACP; acyl carrier protein; ABC; ATP-binding cassette; ABCA1; ATP-binding cassette sub-family A member 1; ABCD3; ATP-binding cassette sub-family D member 3; DAGT1; diacylglycerol O-acyltransferase 1-like;
Microvesicles in the brain: Biomarker, messenger or mediator?
Keywords: ABCA1; ATP-binding cassette transporter A1; AD; Alzheimer's disease; APP; amyloid precursor protein; Aβ; amyloid-beta peptide; CM; cerebral malaria; CNS; central nervous system; CSF; cerebrospinal fluid; EAE; experimental autoimmune encephalomyelitis; EM
Wnt signaling in atherosclerosis
Keywords: ABCA1; ATP binding cassette transporter A1; APC; adenomatous polyposis coli; CAD; coronary artery disease; CAMKII; calmodulin dependent protein kinase II; CK1; casein kinase 1; COX; cyclooxygenase; CRD; cysteine-rich domain; DKK; Dickkopf; EC; endothelial
Triterpenoid-enriched extract of Ilex kudingcha inhibits aggregated LDL-induced lipid deposition in macrophages by downregulating low density lipoprotein receptor-related protein 1 (LRP1)
Keywords: Ilex kudingcha; Triterpenoid-enriched extract; Foam cell; Low density lipoprotein receptor-related protein 1; Latifoloside G (PubChem CID: 44566333); Latifoloside H (PubChem CID: 44566328); ABCA1; ATP-binding cassette subfamily A member-1; AgLDL; aggregat
Diosgenin inhibits atherosclerosis via suppressing the MiR-19b-induced downregulation of ATP-binding cassette transporter A1
Keywords: Diosgenin; ABCA1; Macrophage foam cells; Cholesterol efflux; Reverse cholesterol transport; Atherosclerosis;
MicroRNA-101 overexpression by IL-6 and TNF-α inhibits cholesterol efflux by suppressing ATP-binding cassette transporter A1 expression
Keywords: microRNA; miRNA; miR-101; ATP-binding cassette transporter A1; ABCA1; Cholesterol; Atherosclerosis; Non-alcoholic fatty liver disease; NAFLD; Inflammation; IL-6; TNF-α;
The pleiotropic role of HDL in autoimmune diseases
Keywords: RCT; reverse cholesterol transport; CVD; cardiovascular disease; CAD; coronary artery disease; ApoA1; apolipoprotein A1; APR; acute phase response; PON1; paraoxonase-1; ABCA1; ATP-binding protein A1; ABCG1; ATP-binding protein A1; PAF-AH; platelet-activat
miR-27b inhibits LDLR and ABCA1 expression but does not influence plasma and hepatic lipid levels in mice
Keywords: miRNAs; miR-27b; LDLR; ABCA1; Lipid homeostasis; Atherosclerosis
Interferon-γ in foam cell formation and progression of atherosclerosis
Keywords: IFN-γ; interferon-γ; IFNGR; IFN-γ receptor; VSMC; vascular smooth muscle cell; IL; interleukin; LPS; lipopolysaccharide; TNF-α; tumor necrosis factor-α; STAT; signal transducer and activator of transcription; NF-κB; nuclear factor-κB; TLR; Toll-lik
Potential Signal Transduction Regulation by HDL of the β2-Adrenergic Receptor Pathway. Implications in Selected Pathological Situations
Keywords: HDL; ABCA1; Signal transduction; β2-adrenergic receptor; Adenylyl cyclase; Caveolae;
Inhibition of lipopolysaccharide-induced gene expression by liver X receptor ligands in macrophages involves interference with early growth response factor 1
Keywords: 25HC; 25 hidroxycholesterol; 9cisRA; 9 cis retinoic acid; ABCA1; ATP-binding cassette transporter A1; ABCG1; ATP-binding cassette transporter G1; COX; Cyclooxygenase; Egr-1; early growth response 1; GW; GW3965; LPS; lipopolysaccharide; LUC; luciferase; LX
Saikosaponin a inhibits lipopolysaccharide-oxidative stress and inflammation in Human umbilical vein endothelial cells via preventing TLR4 translocation into lipid rafts
Keywords: ROS; cholesterol; NF-κB; lipid raft; ABCA1;
The liver-selective NO donor, V-PYRRO/NO, protects against liver steatosis and improves postprandial glucose tolerance in mice fed high fat diet
Keywords: Nitric oxide; Hepatoprotection; Liver steatosis; Glucose tolerance; Fatty acid metabolism; ABCA1; ATP-binding cassette transporter family member 1; ACC; native isoform acetyl-CoA carboxylase; Akt; serine/threonine-protein kinase; ALT; alanine aminotransfe
Role of Nrf2 in the pathogenesis of atherosclerosis
Keywords: ABCA1; ATP-binding cassette, sub-family A, member 1; ABCG1; ATP-binding cassette, sub-family G, member 1; ApoE; apolipoprotein E; ARE; antioxidant response element; ArgII; arginase II; CDDO-Im; 2-cyano-3,12 dioxooleana-1,9 dien-28-imidazolide; CXCL4; chem
Cholesterol efflux from THP-1 macrophages is impaired by the fatty acid component from lipoprotein hydrolysis by lipoprotein lipase
Keywords: A/A; antibiotic/antimycotic; ABCA1; ATP binding cassette transporter A1; ABCG1; ATP binding cassette transporter G1; ACCA; acetyl-CoA carboxylase A; apo; apolipoprotein; FAF-BSA; fatty acid free bovine serum albumin; FAS; fatty acid synthase; FFA; free fa
Urotensin II increases foam cell formation by repressing ABCA1 expression through the ERK/NF-κB pathway in THP-1 macrophages
Keywords: Urotensin II; ERK; NF-κB; ABCA1; Cholesterol efflux;
22(R)-hydroxycholesterol and pioglitazone synergistically decrease cholesterol ester via the PPARγ-LXRα-ABCA1 pathway in cholesterosis of the gallbladder
Keywords: Cholesterosis; 22(R)-hydroxycholesterol; Pioglitazone; ABCA1; PPARγ; LXRα;
Down-regulation of lipoprotein lipase increases ABCA1-mediated cholesterol efflux in THP-1 macrophages
Keywords: ABCA1; ATP-binding cassette transporter A1; LPL; lipoprotein lipase; LPL-KD; LPL knock-down; LXR; liver X receptor; PMA; phorbol 12-myristate 13-acetate; PPAR; peroxisome proliferator-activated receptor; RXR; retinoic-X receptor; shRNA; short hairpin RNA;
Chronic supplementation of proanthocyanidins reduces postprandial lipemia and liver miR-33a and miR-122 levels in a dose-dependent manner in healthy rats
Keywords: Flavonoids; microRNAs; Fas; Abca1; Triglycerides; Cholesterol
Partial cloning, tissue distribution and effects of epigallocatechin gallate on hepatic 3-hydroxy-3-methylglutaryl-CoA reductase mRNA transcripts in goldfish (Carassius auratus)
Keywords: ABCA1; ATP-binding cassette transporter A1; BW; body weight; CYP7A1; cholesterol 7alpha-hydroxylase; EGCG; Epigallocatechin gallate; HMGCoAR; 3-hydroxy-3-methylglutaryl-CoA reductase; HMGCoAR-a; 3-hydroxy-3-methylglutaryl-CoA reductase isoform A; HMGCoAR-
Macrophage mitochondrial damage from StAR transport of 7-hydroperoxycholesterol: Implications for oxidative stress-impaired reverse cholesterol transport
Keywords: ABCA1; ATP binding cassette transporter A1; C11-BODIPY; 4,4-difluoro-5-(4-phenyl-1,3-butadienyl)-4-bora-3a,4a-diaza-s-inda-cene-3-undecanoic acid; db-cAMP; dibutyryl-cAMP; ChOOH(s); cholesterol hydroperoxide(s); JC-1; 5,5â²,6,6â²-tetrachloro-1,1â²,3,3â
miR-613 regulates cholesterol efflux by targeting LXRα and ABCA1 in PPARγ activated THP-1 macrophages
Keywords: PPARγ; MicroRNA-613; LXRα; ABCA1; Cholesterol efflux
Growth differentiation factor-15 induces expression of ATP-binding cassette transporter A1 through PI3-K/PKCζ/SP1 pathway in THP-1 macrophages
Keywords: GDF-15; Cholesterol efflux; ABCA1; Atherosclerosis;
NPC1, intracellular cholesterol trafficking and atherosclerosis
Keywords: NPC1; Niemann-Pick type C1; LE/LY; late endosome/lysosome; LDL; low-density lipoprotein; LDL-C; LDL-cholesterol; ER; endoplasmic reticulum; SSD; sterol-sensing domain; NTD; N-terminal domain; apoE; apolipoprotein E; LXR; liver X receptor; OSBP; oxysterolÂ
Impact of the loss of caveolin-1 on lung mass and cholesterol metabolism in mice with and without the lysosomal cholesterol transporter, Niemann-Pick type C1
Keywords: ABCA1; ATP binding cassette transporter A1; ABCG1; ATP binding cassette transporter G1; bw; body weight; Cav-1; Caveolin-1; EC; esterified cholesterol; CYP27A1; sterol-27 hydroxylase; FVB; Friend Leukemia Virus; LAL; lysosomal acid lipase; Npc1; Niemannâ
Creatine reduces hepatic TG accumulation in hepatocytes by stimulating fatty acid oxidation
Keywords: ABCA1; ATP binding cassette protein; AMPK; adenosine monophosphate-activated protein kinase; CT; CTP:phosphocholine cytidylyltransferase; DGAT; acyl CoA:diacylglycerol acyltransferase; HDL; high density lipoproteins; HFD; high-fat diet; HCD; high-carbohyd
Effects of vitamin E on peroxisome proliferator-activated receptor γ and nuclear factor-erythroid 2-related factor 2 in hypercholesterolemia-induced atherosclerosis
Keywords: ABCA1; ATP-binding cassette transporter A1; AP-1; activator protein-1; ARE; antioxidant-response element; CD36; cluster of differentiation 36; GSTα; glutathione S-transferase α; HDL; high-density lipoprotein; HNE; 4-hydroxynonenal; IL-1; interleukin-1;
7-Ketocholesteryl-9-carboxynonanoate enhances ATP binding cassette transporter A1 expression mediated by PPARγ in THP-1 macrophages
Keywords: 7-Ketocholesteryl-9-carboxynonanoate; PPARγ; LXRα; ABCA1; Cholesterol efflux;
Ezetimibe enhances macrophage reverse cholesterol transport in hamsters: Contribution of hepato-biliary pathway
Keywords: RCT; reverse cholesterol transport; CETP; cholesterol ester transfer protein; BDL; bile duct ligation; TICE; transintestinal cholesterol efflux; LDLR; low-density lipoprotein receptor; ABCA1; ATP-binding cassette transporter A; NPC1L1; Niemann-Pick C1-l
Deletion of PARP-2 induces hepatic cholesterol accumulation and decrease in HDL levels
Keywords: ABCA1; adenosine triphosphate-binding cassette transporter A1; ACACA; cetyl-CoA carboxylase alpha; ACLY; ATP citrate lyase; ACOX2; acyl-CoA oxidase 2; ARTD2; ADP-ribosyl transferase diphtheria toxin-like 2; cyp51A1; cytochrome P450, family 51 subfamily A,
ATP-binding cassette transporter A1: From metabolism to neurodegeneration
Keywords: Abca1; HDL; apoE; apoA-I; Alzheimer's disease; Amyloid beta; Cardiovascular disease; LXR; RXR;
Dynamic changes of Apo A1 mediated by LXR/RXR/ABCA1 pathway in brains of the aging rats with cerebral hypoperfusion
Keywords: AD; Alzheimer's disease; VD; vascular dementia; BBB; blood-brain barrier; ABCA1; ATP-binding cassette transporter A1; HDL; high-density lipoprotein; LXR; liver X receptor; RXR; retinoid X receptor; 2VO; 2 vessel occlusion; Vascular dementia; Liver X rec
Increased risk of premature coronary artery disease in Egyptians with ABCA1 (R219K), CETP (TaqIB), and LCAT (4886C/T) genes polymorphism
Keywords: PCAD; HDLc; ABCA1; CETP; LCAT;
Regulation of the cholesterol efflux transporters ABCA1 and ABCG1 in retina in hemochromatosis and by the endogenous siderophore 2,5-dihydroxybenzoic acid
Keywords: RPE; retinal pigment epithelium; ABCA1; ATP-binding cassette transporter A1; ABCG1; ATP-binding cassette transporter G1; Bdh2; β-hydroxybutyrate dehydrogenase-2; 2,5-DHBA; 2,5-dihydroxybenzoic acid; AMD; age-related macular degeneration; pRPE; primary cu
Tiaozhi Tongmai Granules reduce atherogenesis and promote the expression of ATP-binding cassette transporter A1 in rabbit atherosclerotic plaque macrophages and the liver
Keywords: Atherosclerosis; ABCA1; Chinese medicine; Macrophages; LiverABCA1, ATP-binding cassette transporter A1; ALP, alkaline phosphatase; ALT, alanine transaminase; CCA, common carotid artery; CV, central vein; ECA, external carotid artery; HDL-C, high density l
Novel mechanism of transcriptional repression of the human ATP binding cassette transporter A1 gene in hepatic cells by the winged helix/forkhead box transcription factor A2
Keywords: ABCA1; FOXA2; TATA box; Transcriptional repression