LXR activation increases the expression of GnRH AND αMSH in the rat hypothalamus in vivo
Keywords: T0901317; GW3965; GHRH; NPY; ABCA1; GLUT2;
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C1q tumor necrosis factor-related protein 9 in atherosclerosis: Mechanistic insights and therapeutic potential
Keywords: CTRP9; AdipoR1; N-cadherin; Atherosclerosis; Adiponectin; CVD; cardiovascular disease; CTRPs; C1q tumor necrosis factor-related proteins; AMI; acute myocardial infarction; HMW; high molecular weight; AMPK; adenosine monophosphate-activated protein kinase;
Bisphenol A decreases progesterone synthesis by disrupting cholesterol homeostasis in rat granulosa cells
Keywords: Bisphenol A; Granulosa cells; Progesterone; StAR; Cholesterol; Abca1;
Celosins inhibit atherosclerosis in ApoE-/- mice and promote autophagy flow
Keywords: AS; Atherosclerosis; CES; Celosins; LDL; Low-density lipoprotein; Ox-LDL; Oxidized low-density lipoprotein; LC3; Microtubule-associated protein light chain3; CD36; Scavenger receptor B3; SR-A1; Scavenger receptor A 1; ABCA1; ATP-binding cassette transport
Overexpression of transforming growth factor β induced factor homeobox 1 represses NPC1L1 and lowers markers of intestinal cholesterol absorption
Keywords: Cholesterol metabolism; Lipoproteins; Liver; Transcription; Dyslipidemia; ABCA1; ATP-binding cassette transporter A1; ACAT2; acyl-Coenzyme A:cholesterol acyltransferase 2; apo; apolipoprotein; CYP7A1; cholesterol 7α-hydroxylase; HMGCR; 3-hydroxy-3-methyl
Phylogeny and expression patterns of two apolipoprotein E genes in the flatfish Senegalese sole
Keywords: ai; anterior intestine; b; brain; ABCA1; ATP Binding Cassette Subfamily A Member 1; BCIP; bromo-chloro-indolyl-phosphate; CNS; central nervous system; DMSO; dimehtylsulfoxide; dph; days post-hatch; e; eye; HDL; high-density lipoproteins; hb; hindbrain; h;
Ganoderic Acid A improves high fat diet-induced obesity, lipid accumulation and insulin sensitivity through regulating SREBP pathway
Keywords: Ganoderic Acid A; SREBPs; Obesity; Insulin resistance; Lipid accumulation; ABCA1; ATP-binding cassette transporter 1; ACC; acetyl-CoA carboxylase; ACO; acyl-CoA oxidase; BAT; brown adipose tissue; CPT1; carntine palmitoyltransferase 1; CYP7A1; cholesterol
miR-143 and miR-145 promote hypoxia-induced proliferation and migration of pulmonary arterial smooth muscle cells through regulating ABCA1 expression
Keywords: PASMCs; pulmonary artery smooth muscle cells; PAH; pulmonary arterial hypertension; ABCA1; ATP-binding cassette transporter A1; RIP; RNA immunoprecipitation; UTRs; untranslational regions; VSMCs; vascular smooth muscle cells; CCK-8; Cell Counting Kit-8; m
Apelin, a promising target for Alzheimer disease prevention and treatment
Keywords: Alzheimer disease; Apelin; Amyloid beta; Central nervous system; Oxidative stress; AAA; Abdominal aortic aneurysm; ABCA1; ATP-binding cassette transporter A1; ACE; Angiotensin converting enzyme; ACh; Acetylcholine; AChE; Acetyl choline esterase; AD; Alzhe
Ablating both Fabp1 and Scp2/Scpx (TKO) induces hepatic phospholipid and cholesterol accumulation in high fat-fed mice
Keywords: 3αHSD; 3alpha-hydroxysteroid reductase; ABCA1; ATP-binding cassette sub-family A member 1; ABCG1; 4, 5 or 8, ATP-binding cassette sub-family G member 1,4, 5 or 8; ACAT2; acetyl-CoA acetyltransferase (Soat2 gene); ACC1; acetyl-CoA carboxylase (Acaca gene)
Effects of Rosuvastatin on the expression of the genes involved in cholesterol metabolism in rats: adaptive responses by extrahepatic tissues
Keywords: ABCA1; ATP binding cassette subfamily A member 1; ABCG1; ATP binding cassette subfamily G member 1; ApoA1; apolipoprotein A1; HMGCR; 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase; LXR; liver X receptors; PPAR; peroxisome proliferator activated receptor
Tanshindiol C inhibits oxidized low-density lipoprotein induced macrophage foam cell formation via a peroxiredoxin 1 dependent pathway
Keywords: Tan C; Tanshindiol C; oxLDL; oxidized low-density lipoprotein; Nrf2; NF-E2-related factor 2; ARE; antioxidant-response element; Sirt1; Sirtuin 1; Prdx1; peroxiredoxin 1; ABCA1; adenosine triphosphate-binding cassette (ABC) transporter A1; ABCG1; ATP-bindi
Selective peroxisome proliferator-activated receptor-α modulator K-877 regulates the expression of ATP-binding cassette transporter A1 in pancreatic beta cells
Keywords: PPARα; K-877; Cholesterol; ABCA1;
Inhibition of miR-361-5p suppressed pulmonary artery smooth muscle cell survival and migration by targeting ABCA1 and inhibiting the JAK2/STAT3 pathway
Keywords: miR-361-5p; ABCA1; Proliferation; Migration; Apoptosis; JAK2/STAT3 pathway;
Glucagon-like peptide-1 contributes to increases ABCA1 expression by downregulating miR-758 to regulate cholesterol homeostasis
Keywords: GLP-1; Cholesterol homeostasis; ABCA1; miR-758;
Curcumin enhances LXRα in an AMP-activated protein kinase-dependent manner in human macrophages
Keywords: LXR; liver X receptor; ABCA1; ATP-binding cassette transporter A1; ABCG1; ATP-binding cassette transporter G1; SREBP1c; sterol response element binding protein 1c; AMPK; AMP-activated protein kinase; PMA; phorbol myristate acetate; fMLP; formyl-Met-Leu-Ph
Role of ABCA1 on membrane cholesterol content, insulin-dependent Akt phosphorylation and glucose uptake in adult skeletal muscle fibers from mice
Keywords: 2-NBDG; 2-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-d-glucose; ABCA1; ATP binding cassette transporter A1; AMPK; AMP-activated protein kinase; DHPR; Dihydropyridine receptor; DMII; Diabetes mellitus type II; FDB; Flexor digitorum brevis; GLUT4;
Efferocytosis in atherosclerotic lesions: Malfunctioning regulatory pathways and control mechanisms
Keywords: ABC; ATP-binding cassette; ABCA1; ATP-binding membrane cassette transporter A1; ABCG1; ATP binding cassette transporter G1; ABCA7; ATP-binding cassette transporters A7; Abs; Antibodies; ACs; Apoptotic cells; AICAR; 5-aminoimidazole-4-carboxamide-1-β-d-ri
AGE-albumin enhances ABCA1 degradation by ubiquitin-proteasome and lysosomal pathways in macrophages
Keywords: Advanced glycation end products; ABCA1; Atherosclerosis; Macrophages; Proteasome; Lysosome;
MicroRNA-23a-5p promotes atherosclerotic plaque progression and vulnerability by repressing ATP-binding cassette transporter A1/G1 in macrophages
Keywords: Atherosclerosis; miR-23a-5p; ABCA1/ABCG1; Foam cell formation; Plaque vulnerability; AIS; acute ischemic stroke; ACS; acute coronary syndromes; CAD; coronary artery disease; CEUS; Contrast-enhanced ultrasound; miRNAs; MicroRNAs; 3â² UTR; 3â² untranslate
The E3 ubiquitin ligase, HECTD1, is involved in ABCA1-mediated cholesterol export from macrophages
Keywords: ABCA1; ABCG1; Reverse cholesterol transport; Protein ubiquitination; HECTD1; Macrophages;
Oleocanthal-rich extra-virgin olive oil enhances donepezil effect by reducing amyloid-β load and related toxicity in a mouse model of Alzheimer's disease
Keywords: AD; Alzheimer's disease; Aβ; amyloid-β; APP; amyloid precursor protein; ApoE; apo-lipoprotein E; ABCA1; ATP-binding cassette transporter A1; BBB; blood-brain barrier; EVOO; extra-virgin olive oil; GFAP; glial fibrillary acidic protein; IL-1β; inter
Lysine glycation of apolipoprotein A-I impairs its anti-inflammatory function in type 2 diabetes mellitus
Keywords: HDL; high-density lipoprotein; apoA-I; apolipoprotein A-I; ABCA1; ATP-binding cassette transporter A 1; CVD; cardiovascular disease; T2DM; type 2 diabetes mellitus; RCT; reverse cholesterol transport; LPS; lipopolysaccharide; Lys (K); lysine; Glu (E); glu
Cadmium induced redistribution of cholesterol by upregulating ABCA1 and downregulating OSBP
Keywords: Cadmium; Cholesterol; ABCA1; OSBP; Lysosomal acidity; Ubiquitination;
SIRT1 activator E1231 protects from experimental atherosclerosis and lowers plasma cholesterol and triglycerides by enhancing ABCA1 expression
Keywords: SIRT1; LXRα; ABCA1; Cholesterol and lipid metabolism;
Intake of stigmasterol and β-sitosterol alters lipid metabolism and alleviates NAFLD in mice fed a high-fat western-style diet
Keywords: ABCA1; ATP binding cassette transporter A1; ABCG5; ATP binding cassette transporter 5; ALT; alanine aminotransferase; ASBT; ileal apical sodium-dependent bile acid transporter; BA; bile acid(s); BSEP; bile salt export pump; CD36; Cluster of Differentiatio
Long non-coding RNAs regulation in adipogenesis and lipid metabolism: Emerging insights in obesity
Keywords: lncRNAs; Obesity; White adipogenesis; Brown adipocyte differentiation; Lipid metabolism; Therapeutics; WAT; white adipose tissue; BAT; brown adipose tissue; Pparg; peroxisome proliferator-activated receptor γ; Cebpa; CCAAT/enhancer binding protein α; Fa
Digital gene-expression profiling analysis of the fatty liver of Landes geese fed different supplemental oils
Keywords: ABCA1; ATP-binding cassette, sub-family A, member 1; ABCB4; ATP-binding cassette, sub-family B, member 4; ABCC2; ATP-binding cassette, sub-family C, member 2; ABCG5; ATP-binding cassette, sub-family G, member 5; ABCG8; ATP-binding cassette, sub-family G,
Impact of microRNAs on ischemic stroke: From pre- to post-disease
Keywords: AAV; adeno-associated virus; ABCA1; ATP-binding cassette transporter 1; AGO; argonaute; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionate; AT1R; angiotensin II type 1 receptor; AQPs; aquaporins; BBB; blood-brain barrier; Bcl-6; B-cell lymphoma-6;
Hsp27 promotes ABCA1 expression and cholesterol efflux through the PI3K/PKCζ/Sp1 pathway in THP-1 macrophages
Keywords: Hsp27; ABCA1; Cholesterol efflux; Atherosclerosis;
Inhibitory effect of PCSK9 on Abca1 protein expression and cholesterol efflux in macrophages
Keywords: PCSK9; Cholesterol efflux; ABCA1; Macrophage;
Regulation of the expression of LXR in rat hypothalamic and hippocampal explants
Keywords: Glucose; Insulin; Cholesterol; Cholic acid; ABCA1; GLUT2;
Expression of MEGF10 in cholinergic and glutamatergic neurons
Keywords: MEGF10; multiple-EGF like domains 10; ABCA1; ATP binding cassette transporter 1; Aβ42; amyloid-β protein 42; AD; Alzheimer's disease; EMEM; Eagle's minimum essential medium; FBS; fetal bovine serum; GM-CSF; granulocyte macrophage colony stimulating fact
ABCA1 affects placental function via trophoblast and macrophage
Keywords: ABCA1; Cholesterol; Anti-inflammatory; Placenta; Gestation diseases;
LXR agonists promote the proliferation of neural progenitor cells through MEK-ERK pathway
Keywords: Neural progenitor cells; Proliferation; LXR agonists; GW3965; LXR623; ABCA1; ATP-binding cassette, sub-family A (ABC1), member 1; ABCG1; ATP-binding cassette, sub-family G (WHITE), member 1; AD; Alzheimer diseases; CNS; central nervous system; DMEM; Dulbe
Ginger extract increases muscle mitochondrial biogenesis and serum HDL-cholesterol level in high-fat diet-fed rats
Keywords: ABCA1; ATP-binding cassette transporter A1; ApoA-1; apolipoprotein A-1; CYP7A1; 7 alpha-hydroxylase; GEH; high-fat diet containing 0.5% ginger extract; GEL; high-fat diet containing 0.25% ginger extract; HDL-C; high-density lipoprotein-cholesterol; HF; hi
Activation of PPARγ does not contribute to macrophage ABCA1 expression and ABCA1-mediated cholesterol efflux to apoAI
Keywords: TZDs; ABCA1; CD36; Macrophages; Cholesterol efflux; ABCA1/G1; ATP-binding cassette transporter A1/G1; HDL; high-density lipoprotein; LXR; liver X receptor; PPARγ; peroxisome proliferator-activated receptor γ; TZDs; thiazolidinediones;
Cassia auriculata flower extract attenuates hyperlipidemia in male Wistar rats by regulating the hepatic cholesterol metabolism
Keywords: Et- CAF; ethanolic extract of Cassia auriculata flower; HMGR; HMG-CoA reductase; HMGS; HMGCoA synthase; SREBP-1c; sterol regulatory element binding protein -1c; SREBP-2; sterol regulatory element binding protein- 2; CYP7A1; cholesterol 7 α-hydroxylase; A
Current smokers with hyperlipidemia lack elevated preβ1-high-density lipoprotein concentrations
Keywords: ABCA1; Apolipoprotein AI; Cholesterol efflux; Dyslipidemia; HDL metabolism; LCAT; Prebeta-HDL;
Cadmium-induced malignant transformation of rat liver cells: Potential key role and regulatory mechanism of altered apolipoprotein E expression in enhanced invasiveness
Keywords: IARC; International Agency for Research on Cancer; ApoE; Apolipoprotein E; LXR; liver X receptor; LXRE; liver X receptor response element; 5-aza-dC; 5-aza-2â²-deoxycytidine; ABCA1; ATP-binding cassette transporter; SREBP-1c; sterol regulatory element-bin
Hawthorn (Crataegus pinnatifida Bunge) leave flavonoids attenuate atherosclerosis development in apoE knock-out mice
Keywords: HLF; Hawthorn leave flavonoids; HFD; high-fat diet; apoE; apolipoprotein E; ABCA1; ATP binding cassette transporter A1; RCT; reverse cholesterol transport; TC; total cholesterol; VLDLc; very low density lipoprotein cholesterol; LDLc; low density lipoprote
ATP binding cassette A1 (ABCA1) mediates microparticle formation during high-density lipoprotein (HDL) biogenesis
Keywords: HDL; Apolipoprotein apoA-I; Cholesterol efflux; ABCA1; Microparticles; Flotillin-2; CD63;
HDL functionality in type 1 diabetes
Keywords: Type 1 diabetes; HDL functionality; Cholesterol efflux; Anti-oxidant activity; Anti-inflammatory activity; ABCA1; ATP-binding cassette transporter A1; Apo-AI; apolipoprotein AI; Apo; apolipoprotein; CE/TG; ratio of cholesteryl ester-to-triglyceride; CEC;
ABCA1 genetic polymorphisms and type 2 diabetes mellitus and its complications
Keywords: Type 2 diabetes mellitus; ABCA1; Cholesterol; Polymorphism; Meta-analysis;
Effects of curcumin on HDL functionality
Keywords: 2VO; bilateral common carotid artery occlusion; ABCA1; ATP-binding cassette transporter A1; ABCG1; ATP-binding cassette transporter G1; AGE; advanced glycation end products; AIM-HIGH; atherothrombosis intervention in metabolic syndrome with low HDL/high t
Oleocanthal ameliorates amyloid-β oligomers' toxicity on astrocytes and neuronal cells: In vitro studies
Keywords: ABCA1; ATP-binding cassette transporter-A1; ACM; astrocyte-conditioned media; AD; Alzheimer's disease; ApoE; apolipoprotein E; APP; amyloid precursor protein; Aβ; amyloid-β; Aβm; Aβ monomer; Aβo; Aβ oligomers; BBB; blood-brain barrier; BSA; bovi
PARP, transcription and chromatin modeling
Keywords: ABCA1; ATP-binding cassette transporter A1; ADP-ribosylation; adenosine diphosphate ribosylation; ALC1; amplified in-liver-cancer 1; AR; androgen receptor; ARH3; ADP-ribosylhydrolase 3; ART; ADP-ribosyl transferase; ASF/SF2; alternative splicing factor/sp
The apolipoprotein A-I mimetic peptide, D-4F, alleviates ox-LDL-induced oxidative stress and promotes endothelial repair through the eNOS/HO-1 pathway
Keywords: ASCVD; atherosclerotic cardiovascular diseases; HDL; high-density lipoprotein; apoA-I; apolipoprotein A-I; ABCA1; ATP-binding cassette transporter A1; HUVECs; human umbilical vein endothelial cells; HCAECs; human coronary artery endothelial cells; RCT; re
Puerarin promotes ABCA1-mediated cholesterol efflux and decreases cellular lipid accumulation in THP-1 macrophages
Keywords: Puerarin; ABCA1; Cholesterol efflux; Lipid accumulation;
ReviewMildly oxidized HDL decrease agonist-induced platelet aggregation and release of pro-coagulant platelet extracellular vesicles
Keywords: 15-LO; 15-lipoxygenase; ABCA1; ATP-binding casette transporter A1; apo; apolipoprotein; apoA-I; apolipoprotein A-I; apoB; apolipoprotein B; AUC; area under the curve; AU; aggregation units; BCA; bicinchoninic acid assay; BMP; bis(monoacylglycero)phosphate