Keywords: فعال کردن عامل رونویسی; AT1-AA; angiotensin II type 1 receptor agonistic autoantibodies; ATF; activating transcription factor; CH; chronic hypertension; dNK; decidual NK cell; ECM; extracellular matrix; eIF2a; eukaryotic initiation factor 2 subunit a; ER; endoplasmatic reticulum
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Keywords: فعال کردن عامل رونویسی; α-MSH; α-melanocyte stimulating hormone; AGRP; agouti related protein; ARC; arcuate nucleus of hypothalamus; ATF; activating transcription factor; BBB; blood-brain barrier; CRH; corticotropin-releasing hormone; CSF; cerebrospinal fluid; Cys; cysteine; D
Keywords: فعال کردن عامل رونویسی; Akt; protein kinase B; Alg; alginate; ALP; alkaline phosphatase; ATF; activating transcription factor; BFR; bone formation rate; BMD; bone mineral density; BMP; bone morphogenetic protein; BSP; bone sialoprotein; BTE; bone tissue engineering; CIA; collage
Keywords: فعال کردن عامل رونویسی; Taurine; Diabetes mellitus; Oxidative stress; Diabetic complications; Antioxidant; Hypoglycemic effect; ACC; Acetyl-CoA carboxylase; AChE; acetylcholinesterase; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; ATF; activating Transcript
Keywords: فعال کردن عامل رونویسی; ATF4; activating transcription factor; AzPAF; azelaoyl-PAF; AzPC; azelaoyl-PC; CL; cardiolipin; COX; cyclooxygenase; CRP; C-reactive protein; cyt c; cytochrome c; DC; dendritic cell; DMPC; 1,2-dimyristoyl-sn-glycero-3-phosphocholine; EC; endothelial cell;
Keywords: فعال کردن عامل رونویسی; AP-1; activator protein-1; ATF; activating transcription factor; bZIP; basic region leucine zipper; CRE; cyclic AMP response element; CREB; cAMP response element binding protein; Nrf2; NF-E2-related factor-2; SRE; serum response element; SRF; serum respon
Keywords: فعال کردن عامل رونویسی; Berberine; Inflammatory bowel disease; Anti-inflammatory mechanisms; Antinociceptive; Epithelial barrier protection; Anti-diarrhoeal; AP1; activator protein 1; ATF; activating transcription factor; COX-2; cyclooxygenase-2; ERK1/2; extracellular signal-reg
Keywords: فعال کردن عامل رونویسی; Endothelial dysfunction; Endoplasmic reticulum stress; Cardiovascular risk; Chronic inflammation; AP; activator protein; ASK1; apoptosis-signaling-kinase 1; ATF; activating transcription factor; b-ZIP; basic leucine zipper; CHOP; C/EBP homologous protein;
Keywords: فعال کردن عامل رونویسی; NASH; CHOP; JNK; Lipid; Oxidative stress; ALA; alpha-linolenic; ACC; acetyl-CoA carboxylase; AMPK; AMP-activated protein kinase; ATF; activating transcription factor; AP-1; activator protein-1; BAs; bile acids; BH3; Bcl-2 homology 3; BIM; Bcl-2 interactin
Keywords: فعال کردن عامل رونویسی; Oxysterols; Survival; Nrf2; Autophagy; 5,6-S; 5,6-secosterol; 24OH; 24-hydroxycholesterol; 25OH; 25-hydroxycholesterol; 27OH; 27-hydroxycholesterol; 7K; 7-ketocholesterol; 7βOH; 7β-hydroxycholesterol; AGE; advanced glycation end products; AMPK; AMP-acti
Keywords: فعال کردن عامل رونویسی; AP-1; activator protein 1; ATF; activating transcription factor; COX-2; cyclooxygenase-2; CRE; cAMP response element; CREB; cAMP response element-binding protein; DNA; deoxyribonucleic acid; EGFR; epidermal growth factor receptor; ERK; extracellular signa
Keywords: فعال کردن عامل رونویسی; Ad; adenovirus; ATF; activating transcription factor; BMDM; bone marrow-derived macrophage; bZIP; basic region leucine zipper; ERK1/2; extracellular-regulated protein kinases 1 and 2; Gal; D-galactosamine; IκB; inhibitory κB; LPS; lipopolysaccharide; NF
Keywords: فعال کردن عامل رونویسی; AD; Alzheimer׳s disease; ALS; amyotrophic lateral sclerosis; ApoE; apolipoprotein E; AP-1; activator protein-1; β-APP; β-amyloid precursor protein; ATF; activating transcription factor; ATP; adenosine triphosphate; BBB; blood brain barrier; BCSFB; bloo
Keywords: فعال کردن عامل رونویسی; endoplasmic reticulum stress; unfolded protein response; retinal degeneration; cell death; apoptosis; inflammation; AMD; age-related macular degeneration; ASK1; apoptosis signal-regulating kinase 1; ATF; activating transcription factor; Bip; immunoglobuli
Keywords: فعال کردن عامل رونویسی; AD; Alzheimer's disease; AIF; apoptosis-inducing factor; AM; acetoxymethyl ester; APP; amyloid precursor protein; ATF; activating transcription factor; Aβ; amyloid-beta; BBB; blood-brain barrier; bFGF; basic fibroblast growth factor; CHOP; CAAT/enhance
The mechanisms and clinical significance of PDCD4 in colorectal cancer
Keywords: فعال کردن عامل رونویسی; Abbreviations; Full name in English; 3â²-UTR; 3â²-untranslated region; AA; asiatic acid; AOM; azoxymethane; AP-1; activating protein 1; AR; aldose reductase; ATF; activating transcription factor; Bcl-2; B-cell lymphoma 2; CAC; colitis-associated CRC; CD
Regulation of the ATF3 gene by a single promoter in response to amino acid availability and endoplasmic reticulum stress in human primary hepatocytes and hepatoma cells
Keywords: فعال کردن عامل رونویسی; AA; amino acid; AAR; AA response; ATF; activating transcription factor; C/EBP; CAAT/enhancer binding protein; CARE; C/EBP-ATF response element; CRE; cyclic AMP response element; IF2; eukaryotic initiation factor 2; GAPDH; glyceraldehyde 3-phosphate dehydr
TRIB3 limits FGF21 induction during in vitro and in vivo nutrient deficiencies by inhibiting C/EBP-ATF response elements in the Fgf21 promoter
Keywords: فعال کردن عامل رونویسی; ATF; activating transcription factor; C/EBP; CCAAT/enhancer-binding protein; ER; endoplasmic reticulum; FGF21; fibroblast growth factor 21; MEF; mouse embryonic fibroblast; PPARα; peroxisome proliferator-activated receptor α; TRIB3; Tribbles homolog 3;
The unknown face of IRE1α - Beyond ER stress
Keywords: فعال کردن عامل رونویسی; ER; endoplasmic reticulum; UPR; unfolded protein response; IRE1; inositol requiring kinase enzyme 1; XBP1; x-box binding protein 1; bZIP; basic leucine zipper domain; HAC1; histone acetyl transferase 1; ATF; activating transcription factor; RIDD; regulate
Curcumin induces osteoblast differentiation through mild-endoplasmic reticulum stress-mediated such as BMP2 on osteoblast cells
Keywords: فعال کردن عامل رونویسی; ER; endoplasmic reticulum; BMP; bone morphogenetic protein; Runx2; Runt-related transcription factor 2; OC; osteocalcin; UPR; unfolded protein response; PERK; PKR-like endoplasmic reticulum kinase; IRE-1; inositol-requiring enzyme 1; ATF; activating trans
Lysine demethylase inhibition protects pancreatic β cells from apoptosis and improves β-cell function
Keywords: فعال کردن عامل رونویسی; Apoptosis; β cells; Inflammation; Lysine demethylases; Gene expression; Diabetes; ATF; Activating transcription factor; ChIP; Chromatin immunoprecipitation; CHOP; C/EBP homologous protein; DP; Death promoting gene; ER; Endoplasmic reticulum; FDH; Formald
Ca2+ signaling and Src-kinases-controlled cellular functions
Keywords: فعال کردن عامل رونویسی; Ca2+ channels; Cell signaling; Phosphatases; Receptors; Src-family kinases; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxyli
Plasma cell deficiency in human subjects with heterozygous mutations in Sec61 translocon alpha 1 subunit (SEC61A1)
Keywords: فعال کردن عامل رونویسی; SEC61A1; translocon; protein translocation; antibody deficiency; plasma cell; multiple myeloma; calcium homeostasis; endoplasmic reticulum stress; ADTKD; Autosomal dominant tubulointerstitial and glomerulocystic kidney disease; ATF; Activating transcripti
Intracellular signaling modifications involved in the anti-inflammatory effect of 4-alkoxy-6,9-dichloro[1,2,4]triazolo[4,3-a]quinoxalines on macrophages
Keywords: فعال کردن عامل رونویسی; ATF; activating transcription factor; CCM; complete culture medium; ERK; extracellular signal-regulated kinase; IKK; IκB kinase; IL-6; interleukin 6; JNK; c-Jun N-terminal kinase; LPS; lipopolysaccharide; MAPK; mitogen-activated protein kinase; NSAIDs; n
Crosstalk control and limits of physiological c-Jun N-terminal kinase activity for cell viability and neurite stability in differentiated PC12 cells
Keywords: فعال کردن عامل رونویسی; Akt; protein kinase B; ATF; activating transcription factor; ATP; adenosine triphosphate; BH3; Bcl-2 homology domain 3; cIAP1; cellular inhibitor of apoptosis 1; CREB; cAMP response element-binding protein; ECL; enhanced chemiluminescence; EDTA; ethylened
Growth arrest and DNA damage-inducible 45α protects against nonalcoholic steatohepatitis induced by methionine- and choline-deficient diet
Keywords: فعال کردن عامل رونویسی; NASH; nonalcoholic steatohepatitis; FA; fatty acid; DG; diacylglycerol; ER; endoplasmic reticulum; Gadd45; growth arrest and DNA damage-inducible 45; DMBA; dimethylbenzanthracene; WT; wild-type; ATF; activating transcription factor; MCD; methionine- and c
Pulmonary ORMDL3 is critical for induction of Alternaria-induced allergic airways disease
Keywords: فعال کردن عامل رونویسی; ORMDL3; asthma; unfolded protein response; uric acid; Alternaria; AAD; Allergic airways disease; AAV; Adeno-associated viral vector; AHR; Airway hyperreactivity; ATF; Activating transcription factor; BALF; Bronchoalveolar lavage fluid; EGFP; Enhanced gree
ReviewEndoplasmic reticulum stress and eIF2α phosphorylation: The Achilles heel of pancreatic β cells
Keywords: فعال کردن عامل رونویسی; Diabetes; Endoplasmic reticulum stress; eIF2α; Pancreatic β cell; Insulin; Islet; ATF; activating transcription factor; CHOP; C/EBP homologous protein; CReP; constitutive repressor of eIF2α phosphorylation; CRISPR; clustered regularly interspaced short
ATF3 modulates calcium signaling in osteoclast differentiation and activity by associating with c-Fos and NFATc1 proteins
Keywords: فعال کردن عامل رونویسی; ATF3; activating transcription factor; BMM; bone marrow-derived monocyte/macrophage lineage cell; NFATc1; nuclear factor of activated T-cells c1; TRAP; tartrate-resistant acid phosphatase; RANKL; receptor activator of nuclear factor-κB ligand; Osteoclast
Targeting chaperones, heat shock factor-1, and unfolded protein response: Promising therapeutic approaches for neurodegenerative disorders
Keywords: فعال کردن عامل رونویسی; 17-AAG; 17-(allylamino)-17-demethoxygeldanamycin (tanespimycin); 17-DMAG; 17- dimethylaminoethylamino-17-demethoxygeldanamycin (alvespimycin); AAV; adeno-associated virus; Aβ; amyloid-β; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP;
ATF7 ablation prevents diet-induced obesity and insulin resistance
Keywords: فعال کردن عامل رونویسی; ATF7; Metabolism; Obesity; Insulin resistance; ATF; activating transcription factor;
Anti-TNF-α and anti-arthritic effect of patuletin: A rare flavonoid from Tagetes patula
Keywords: فعال کردن عامل رونویسی; RA; rheumatoid arthritis; TNF; tumor necrosis factor; NO; nitric oxide; IL; interleukin; ROS; reactive oxygen species; AIA; adjuvant induced arthritis; MMP; matrix metalloproteinase; PMNs; polymorphonuclear cells; PO; peroxide; RF; rheumatoid factor; SD;
Astemizole-Histamine induces Beclin-1-independent autophagy by targeting p53-dependent crosstalk between autophagy and apoptosis
Keywords: فعال کردن عامل رونویسی; AST; Astemizole; HIS; Histamine; H1R; Histamine H1 receptor; ROS; Reactive oxygen species; ER; Endoplasmic reticulum; PERK; Protein kinase R-like endoplasmic reticulum kinase; IRE1α; Inositol-requiring enzyme 1; ATF; Activating transcription factor; JNK;
TRIB3 increases cell resistance to arsenite toxicity by limiting the expression of the glutathione-degrading enzyme CHAC1
Keywords: فعال کردن عامل رونویسی; ATF; activating transcription factor; BSO; buthionine sulfoximine; C/EBP; CCAAT/enhancer-binding protein; CHAC1; ChaC glutathione-specific γ-glutamylcyclotransferase 1; CREB; cAMP response element-binding protein; eIF2α; eukaryotic translation initiatio
Acrolein Is a Pathogenic Mediator of Alcoholic Liver Disease and the Scavenger Hydralazine Is Protective in Mice
Keywords: فعال کردن عامل رونویسی; Lipid Peroxidation; Apoptosis; Therapeutic; CHOP; ADH; alcohol dehydrogenase; ALD; alcoholic liver disease; ALDH; aldehyde dehydrogenase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; ATF; activating transcription factor; CHOP; CCAAT/enh
Embryonal Fyn-associated substrate (EFS) and CASS4: The lesser-known CAS protein family members
Keywords: فعال کردن عامل رونویسی; 5-HT; 5-hydroxytryptamine, serotonin; A549; non-small cell lung cancer cell line; AD; Alzheimer's disease; ADPKD; autosomal dominant polycystic kidney disease; Aire; autoimmune regulator; AP-1; activator protein 1; APP; amyloid precursor protein; AREB6; Z
Repeated forced swim stress prior to complete Freund's adjuvant injection enhances mechanical hyperalgesia and attenuates the expression of pCREB and ÎFosB and the acetylation of histone H3 in the insular cortex of rat
Keywords: فعال کردن عامل رونویسی; ACC; anterior cingulate cortex; ADX; adrenalectomy; AIC; anterior insular cortex; AMPA; aminomethylphosphonic acid; ANOVA; analysis of variance; AP-1; activator protein-1; ATF; activating transcription factor; BSA; bovine serum albumin; CBP; CREB-binding
Ilexgenin A inhibits endoplasmic reticulum stress and ameliorates endothelial dysfunction via suppression of TXNIP/NLRP3 inflammasome activation in an AMPK dependent manner
Keywords: فعال کردن عامل رونویسی; ACC; acetyl-CoA carboxylase; ACh; acetylcholine; AICAR; AICA riboside; AMPK; AMP-activated protein kinase; ATF; activating transcription factor; ER; endoplasmic reticulum; FBS; fetal bovine serum; FFAs; free fatty acids; HFD; high-fat diet; IRE1α; inosit
Dual role for CHOP in the crosstalk between autophagy and apoptosis to determine cell fate in response to amino acid deprivation
Keywords: فعال کردن عامل رونویسی; AARE; amino acid response element; ATF; activating transcription factor; bZIP; basic leucine zipper; Bim; Bcl2 interacting mediator of cell death; ChIP; chromatin immunoprecipitation; CHOP; C/EBP homologous protein; EGFP; enhanced green fluorescent protei
PKC-mediated HuD-GAP43 pathway activation in a mouse model of antiretroviral painful neuropathy
Keywords: فعال کردن عامل رونویسی; aODN; antisense oligonucleotide; ATF3; activating transcription factor; ddC; 2â²,3â²-dideoxycitidine; dODN; degenerate oligonucleotide; ELAV protein; embryonic lethal abnormal vision protein; GAP-43; growth-associated protein; HAART; highly active antir
Cholesterol biosynthesis and ER stress in peroxisome deficiency
Keywords: فعال کردن عامل رونویسی; Peroxisomes; Cholesterol; Isoprenoid; Pex2; SREBP-2; ER stress; Integrated stress response; Unfolded protein response; Zellweger syndrome; ACAT; acetoacetyl-CoA thiolase; ATF; activating transcription factor; BA; bile acid; CHOP; C/EBP homologous protein;
Targeting Nrf2-Keap1 signaling for chemoprevention of skin carcinogenesis with bioactive phytochemicals
Keywords: فعال کردن عامل رونویسی; 4-HNE; 4-hydroxynonenal; 8OH-dG; 8-hydroxy-2â²deoxyguanosine; AMPK; cyclic-AMP-activated protein kinase; ARE; antioxidant response element; ATF; activating transcription factor; B[a]P; Benzo[a]pyrene; Bach1; broad-complex, tramtrack and bric a brac; CBP;
Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts
Keywords: فعال کردن عامل رونویسی; H2-DCFH-DA; 2â²,7â²-dichlorodihydrofluorescein diacetate; 5-Aza; 5-aza-2â²-deoxycytidine; 5-mC; 5-methylcytosine; ATF; activating transcription factor; AID; activation-induced deaminase; AGE; advanced glycation end-product; ARC; age-related cataract; A
Calumenin has a role in the alleviation of ER stress in neonatal rat cardiomyocytes
Keywords: فعال کردن عامل رونویسی; ATF; activating transcription factor; Ad-calu; adenovirus containing mouse calumenin 1 cDNA; Ad-lacZ; adenovirus containing lacZ gene; CHOP; C/EBP-homologous protein; ERAD; ER-associated degradation; eIF2; eukaryotic initiation factor 2; ERp57; the thiol
Acidosis blocks CCAAT/enhancer-binding protein homologous protein (CHOP)- and c-Jun-mediated induction of p53-upregulated mediator of apoptosis (PUMA) during amino acid starvation
Keywords: فعال کردن عامل رونویسی; AAR; amino acid response; Apaf-1; apoptotic protease-activating factor-1; ATF; activating transcription factor; Bcl-2; B cell lymphoma-2; Bax; Bcl-2-associated X protein; Bim; Bcl-2-interacting mediator of cell death; CHOP; CCAAT/enhancer-binding protein
Activation of the antioxidant response in methionine deprived human cells results in an HSF1-independent increase in HSPA1A mRNA levels
Keywords: فعال کردن عامل رونویسی; Heat shock factor 1; Amino acid deprivation; Methionine; DNAJB1; NRF2; GCN2; general non-derepressible 2; ATF; activating transcription factor; ASNS; asparagine synthetase; SAM; S-adenosylmethionine; HMOX1; heme oxygenase 1; GSTP; glutathione S-transferas
Regulation of inositol 1,4,5-trisphosphate receptors during endoplasmic reticulum stress
Keywords: فعال کردن عامل رونویسی; a.a.; amino acid; ATF; activating transcription factor; Bcl-2; B-cell lymphoma 2; Bcl-Xl; B-cell lymphoma-extra large; BH3; Bcl-2 homology 3; BI-1; Bax inhibitor-1; BiP; immunoglobulin heavy chain-binding protein; CHOP; C/EBP-homologous protein; CSQ; cals
Protective effects of (â)-epigallocatechin-3-gallate against TNF-α-induced lung inflammation via ROS-dependent ICAM-1 inhibition
Keywords: فعال کردن عامل رونویسی; APO; apocynin; ATF; activating transcription factor; BAL; bronchoalveolar lavage; CO; carbon monoxide; DPI; diphenyleneiodonium chloride; EGCG; (â)-epigallocatechin-3-gallate; HO; heme oxygenase; SOCS; suppressors of cytokine signaling.; Cytokines; Reac
Sorafenib enhances proteasome inhibitor-mediated cytotoxicity via inhibition of unfolded protein response and keratin phosphorylation
Keywords: فعال کردن عامل رونویسی; Ab; antibody; ALLN; acetyl-leucyl-leucyl-norleucinal; ATF; activating transcription factor; CHOP; C/EBP homologous protein; DAPI; 4', 6-diamidino-2-phenylindole; eIF2; eukaryotic translation-initiation factor 2; ER; endoplasmic reticulum; GADD153; growth
Trib3 is regulated by IL-3 and affects bone marrow-derived mast cell survival and function
Keywords: فعال کردن عامل رونویسی; ATF; activating transcription factor; BMMCs; bone marrow-derived mast cells; BSA; bovine serum albumin; C/EBP; CCAAT/enhancer binding protein; CHOP; C/EBP homologous protein; DAPI; 4â²,6-diamidino-2-phenylindole; DNP; dinitrophenyl; Epo; erythropoietin;