دانلود مقالات ISI درباره Adohcy + ترجمه فارسی

ارزیابی هلیکاز ویروس دنگی و متیل ترانسفراز به عنوان هدف برای کشف مواد مخدر مبتنی بر قطعه

Assessment of Dengue virus helicase and methyltransferase as targets for fragment-based drug discovery

Keywords: DENV; Dengue virus; NS; non-structural protein; MTase; methyltransferase; Hel; helicase; AdoMet; S-adenosyl-l-methionine; AdoHcy; S-adenosyl-l-homocysteine; FBDD; fragment-based drug discovery; FBS; fragment-based screening; FBS-X; FBS by X-ray crystallog

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

یک جهش فعال در محل پروتئین اسید چرب اشرشیا کولی، سیکلوپروپان اسید چرب باعث ایجاد اسیدهای چرب غیر طبیعی می شود که از بین می رود. مکانیسم واکنش آنزیمی

An active site mutant of Escherichia coli cyclopropane fatty acid synthase forms new non-natural fatty acids providing insights on the mechanism of the enzymatic reaction

Keywords: Cyclopropane fatty acid synthase; Mycolic acid methyltransferase; Fatty acid methyl ester; Enzyme mechanism; AdoHcy; S-adenosyl-l-homocysteine; AdoMet; S-adenosyl-l-methionine; CS; cyclopropane synthase; CFAS; cyclopropane fatty acid synthase; CMAS; cyclo

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Confirmation that MAT1A p.Ala259Val mutation causes autosomal dominant hypermethioninemia

Keywords: MAT; methionine adenosyltransferase; PPPase; tripolyphosphatase; AdoMet; S-adenosyl-methionine; WT; wild-type; AdoHcy; S-adenosyl-homocysteine; Methionine adenosyltransferase I/III deficiency; Hypermethioninemia; MAT1A; Mudd's disease;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Hepatoprotective naphthalene diglucoside from Neanotis wightiana aerial parts

Keywords: Neanotis wightiana; Rubiaceae; Naphthalene diglucoside; Extensive spectroscopy; Hepatoprotective; AdoHcy; S-adenosyl homocysteine; Ado-Met; S-adenosyl methionine; ALP; alkaline phosphatase; ANOVA; analysis of variance; bw; body weight; CC; column chromato

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Mutations in S-adenosylhomocysteine hydrolase (AHCY) affect its nucleocytoplasmic distribution and capability to interact with S-adenosylhomocysteine hydrolase-like 1 protein

Keywords: Aa; amino acid; ADK; adenosine kinase; AdOx; adenosine-2′,3′-dialdehyde; AHCY; S-adenosylhomocysteinase; AHCYL1 (IRBIT); adenosylhomocysteinase-like 1 (inositol 1,4,5-trisphosphate receptor-binding protein); AdoMet; S-adenosylmethionine; AdoHcy; S-ade

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Leptin concentrations and SCD-1 indices in classical homocystinuria: Evidence for the role of sulfur amino acids in the regulation of lipid metabolism

Keywords: AdoHcy; S-adenosylhomocysteine; AdoMet; S-adenosylmethionine; BIA; bioelectrical impedance analysis; BMD; bone mineral density; CβS; cystathionine β-synthase; DXA; dual X-ray absorptiometry; FAMEs; fatty acid methyl esters; GSH; glutathione; HCU; classi

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design

Keywords: Phenyl [(phenylcarbamoyl)amino]benzene-1-sulfonate derivatives; N-Phenyl-[(phenylcarbamoyl)amino]benzene-1-sulfonamide derivatives; Fragment-linking strategy; Dengue virus; NS5 methyltransferase inhibitors; Antiviral activity; DENV; dengue virus; NS; non-

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2017 سفارش ترجمه

Betaine homocysteine S-methyltransferase emerges as a new player of the nuclear methionine cycle

Keywords: AdoHcy; S-adenosylhomocysteine; AdoMet; S-adenosylmethionine; AGFC; analytical gel filtration chromatography; AHCY; S-adenosylhomocysteine hydrolase; APAP; acetaminophen; BHMT; betaine homocysteine methyltransferase; BSO; buthionine sulfoximine; EGSH; glu

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2017 سفارش ترجمه

Understanding protein arginine methyltransferase 1 (PRMT1) product specificity from molecular dynamics

Keywords: PRMT1; protein arginine methyltransferase 1; MMA; monomethylarginine; ADMA; asymmetric dimethylarginine; SDMA; symmetric dimethylarginine; AdoMet; S-adenosylmethionine; AdoHcy; S-adenosyl-l-homocysteine; GGRGG; Gly-Gly-Arg-Gly-Gly; NAC; near-attack confor

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Bioenergetic relevance of hydrogen sulfide and the interplay between gasotransmitters at human cystathionine β-synthase

Keywords: H2S; hydrogen sulfide; NO; nitric oxide; CO; carbon monoxide; CcOX; cytochrome c oxidase; CBS; cystathionine β-synthase; AdoMet; S-adenosyl-l-methionine; CGL; cystathionine γ-lyase; PLP; pyridoxal 5′-phosphate; MST; 3-mercaptopyruvate sulfurtransferas

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2016 سفارش ترجمه

Crystal structure and activity of protein L-isoaspartyl-O-methyltransferase from Vibrio cholerae, and the effect of AdoHcy binding

Keywords: AdoHcy binding; Crystal structure; Enzyme activity; Methyltransferase; Protein repair; PIMT; protein L-isoaspartyl-O-methyltransferase; AdoMet; S-adenosylmethionine; AdoHcy; S-adenosyl-L-homocysteine; PEG; polyethylene glycol; DHBS; 3,5-dichloro-2-hydroxy

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2015 سفارش ترجمه

DZNep, inhibitor of S-adenosylhomocysteine hydrolase, down-regulates expression of SETDB1 H3K9me3 HMTase in human lung cancer cells

Keywords: DZNep; 3-Deazaneplanocin A; AdoHcy; S-adenosyl homocystein; AdoMet; S-adenosyl-methionine; H3K9me3; trimethylation of histone H3 at lysine 9; H3K27me3; trimethylation of histone H3 at lysine 27; EZH2; enhancer of zeste homolog 2; PRC2; polycomb repressor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Physiological roles of phosphatidylethanolamine N-methyltransferase

Keywords: AdoMet; S-adenosylmethionine; AdoHcy; S-adenosylhomocysteine; CT; CTP:phosphocholine cytidylyltransferase; DHA; docosahexaenoic acid; ER; endoplasmic reticulum; Hcy; homocysteine; LCTαKO; liver-specific CTα knockout; PC; phosphatidylcholine; PE; phospha

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Protein l-isoaspartyl-O-methyltransferase of Vibrio cholerae: Interaction with cofactors and effect of osmolytes on unfolding

Keywords: Methyltransferase; Folding intermediate; Osmolytes; Protein modeling and simulation; AdoMet; S-adenosyl methionine; AdoHcy; S-adenosyl homocysteine; bis-ANS; 4,4′-dianilino-1,1′-binaphthyl-5,5′-disulfonic acid; CD; circular dichroism; DLS; dynamic l

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Sulfur-based redox alterations in long-lived Snell dwarf mice

Keywords: 5-Me-dCMP; 5-methyl-2′-deoxycytidine-5′-monophosphate; AdoHcy; S-adenosylhomocysteine; AdoMet; S-adenosylmethionine; AHC; adenosylhomocysteine hydrolase (adenosylhomocysteinase); BHMT; betainehomocysteinemethyltransferase; CBS; cystathionineβ-synthas

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

S-adenosyl-L-homocysteine hydrolase and methylation disorders: Yeast as a model system

Keywords: AdoMet; AdoHcy; Homocysteine; S-adenosyl-L-homocysteine hydrolase;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Differences in folate-protein interactions result in differing inhibition of native rat liver and recombinant glycine N-methyltransferase by 5-methyltetrahydrofolate

Keywords: GNMT; glycine N-methyltransferase; AdoMet; S-adenosylmethionine; AdoHcy; S-adenosylhomocysteine; 5-CH3-H4PteGlu1; 5-methyltetrahydropteroyl monoglutamate; 5-CH3-H4Pte-Glu5; 5-methyltetrahydropteroyl pentaglutamate; Glycine N-methyltransferase; Folate; Cry

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Long-term betaine therapy in a murine model of cystathionine beta-synthase deficient homocystinuria: Decreased efficacy over time reveals a significant threshold effect between elevated homocysteine and thrombotic risk

Keywords: ALT; Alanine aminotransferase; BHMT; betaine-homocysteine S-methyltransferase; HCU; classical homocystinuria; CBS; cystathionine beta-synthase; CGL; cystathionine gamma-lyase; GNMT; glycine N-methyltransferase; Hcy; homocysteine; IL-1b; interleukin-1beta;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Cancers and the NSD family of histone lysine methyltransferases

Keywords: NSD; nuclear receptor binding SET domain; HMTase; Histone Methyl Transferase; AdoMet; S-Adenosylmethionine; AdoHcy; S-Adenosylhomocysteine; Transcription factor; Histone lysine methyl transferase; NSD1; NSD2/MMSET/WHSC1; NSD3/WHSC1L1; Epigenetic cancer th

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

The logic of the hepatic methionine metabolic cycle

Keywords: AdoMet; S-adenosylmethionine; AdoHcy; S-adenosylhomocysteine; AHC; adenosylhomocysteinase; BHMT; betaine homocysteine S-methyltransferase; CBS; cystathionine β-synthase; GSH; glutathione; GNMT; glycine-N-methyltransferase; Hcy; homocysteine; MATI/II; III

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Cystathionine beta-synthase null homocystinuric mice fail to exhibit altered hemostasis or lowering of plasma homocysteine in response to betaine treatment

Keywords: ALT; Alanine aminotransferase; aPTT; activated partial thromboplastin time; BHMT; betaine-homocysteine S-methyltransferase; HCU; classical homocystinuria; CBS; cystathionine beta-synthase; CGL; cystathionine gamma-lyase; DMG; dimethylglycine; ER; endoplas

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Inhibition of human catechol-O-methyltransferase (COMT)-mediated O-methylation of catechol estrogens by major polyphenolic components present in coffee

Keywords: 2-OH-E2; 2-hydroxyestradiol; 4-OH-E2; 4-hydroxyestradiol; COMT; catechol-O-methyltransferase; AdoMet; S-adenosyl-l-methionine; AdoHcy; S-adenosyl-l-homocysteine; CAPE; caffeic acid phenethyl ester; Coffee polyphenols; Catechol estrogens; 2-Hydroxyestradio

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

The antiviral drug ribavirin is a selective inhibitor of S-adenosyl-l-homocysteine hydrolase from Trypanosoma cruzi

Keywords: 2× YT; 2× yeast extract tryptone; Ado; adenosine; AdoHcy; S-adenosyl-l-homocysteine; DTT; dl-Dithiothreitol; EDTA; ethylenediaminetetraacetic acid; FPLC; fast protein liquid chromatography; Hcy; l-homocysteine; HPLC; high performance liquid chromatograp

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

An enzyme-coupled continuous spectrophotometric assay for S-adenosylmethionine-dependent methyltransferases

Keywords: S-adenosyl-methionine; AdoMet; SAM; S-adenosyl-homocysteine; AdoHcy; SAH; Methyltransferase; Protein arginine methylation; PRMT; AdoHcy nucleosidase; Adenine deaminase; MTAN; S-ribosylhomocysteine

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Processing the message: structural insights into capping and decapping mRNA

Keywords: AdoHcy; S-adenosylhomocysteine; AdoMet; S-adenosylmethionine; CTD; C-terminal domain; EVH1; Ena/VASP homology 1; HIT; histidine triad; NT; nucleotidyl transferase; pol II; RNA polymerase II; PRS; proline-rich sequence; TGFβ; transformation growth factor-

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Expression and activity of l-isoaspartyl methyltransferase decrease in stage progression of human astrocytic tumors

Keywords: Disorders of the nervous system; Neuro-oncology; AdoHcy; S-adenosyl-l-homocysteine; AdoMet; S-adenosyl-l-methionine; BSA; bovine serum albumin; DSIP-isoD; delta-sleep-inducing peptide; ECL; enhanced chemiluminescence; GAPDH; glyceraldehyde-3-phosphate deh

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Disulfide-linked dimers of human adrenaline synthesizing enzyme PNMT are catalytically active

Keywords: AdoHcy; S-adenosyl-l-homocysteine; AdoMet; S-adenosyl-l-methionine; βME; β-mercaptoethanol; AUC; analytical ultracentrifugation; DTT; dithiothreitol; EDTA; ethylene-diamine tetraacetic acid; GSH; reduced glutathione; GSSG; oxidized glutathione; PAGE; po

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Hydroxytyrosol, a natural antioxidant from olive oil, prevents protein damage induced by long-wave ultraviolet radiation in melanoma cells

Keywords: AdoHcy; S-adenosylhomocysteine; AdoMet; S-adenosylmethionine; COMT; catechol-O-methyltransferase; DCF; 2′7′-dichlorofluorescein; DCFH-DA; 2′-7′-dichlorofluorescein diacetate; DOPET; 3,4-dihydroxyphenylethanol; FCS; fetal calf serum; HPLC; high-per

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه