Keywords: AHR، پاسخگویی هوایی; ACOS; Elderly asthma; Emphysema; HRCT; PhenotypeACOS, asthma-COPD overlap syndrome; AHR, Airway hyperresponsiveness; COPD, chronic obstructive pulmonary disease; DLCO, diffusion capacity of the lung for carbon monoxide; FeNO, fraction of exhaled nitric ox
مقالات ISI AHR، پاسخگویی هوایی (ترجمه نشده)
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Keywords: AHR، پاسخگویی هوایی; Asthma; Airway remodeling; Azithromycin; MacrolideOVA, ovalbumin; LPS, lipopolysaccharide; BAL, bronchoalveolar lavage; AHR, airway hyperresponsiveness; IL, Interleukin; MAPK, mitogen-activated protein kinases; NF, nuclear factor; BRP, breast regression p
Keywords: AHR، پاسخگویی هوایی; RSV, Respiratory syncytial virus; AHR, Airway hyperresponsiveness; TLRs, Toll like receptors; BALF, Bronchoalveolar lavage fluid; NGF, Nerve growth factor; BDNF, Brain-derived neurotrophic factorRSV; Persistent airway inflammation; Persistent AHR; NGF; Re
Keywords: AHR، پاسخگویی هوایی; ACQ, Asthma Control Questionnaire; AHR, airway hyperresponsiveness; AQLQ, Asthma Quality of Life Questionnaire; MCT, methacholine challenge test; MET, metabolic equivalent task; PC20, provocative concentration of methacholine causing a 20' fall in FEV1
Keywords: AHR، پاسخگویی هوایی; Lvn, lavender essential oil; BAL, bronchoalveolar lavage; AHR, airway hyperresponsiveness; RL, lung resistance; OVA, ovalbuminLavender; Asthma; Alternative medicine; Cytokines; Mucin
Keywords: AHR، پاسخگویی هوایی; AAA, abdominal aortic aneurysm; AD, atopic dermatitis; AHR, airway hyperresponsiveness; BMDC, bone marrow-derived cell; CSC, cancer stem cell; ECM, extracellular matrix; FAK, focal adhesion kinase; IPF, idiopathic pulmonary fibrosis; LOX, lysyl oxidase; M
Keywords: AHR، پاسخگویی هوایی; airway hyperresponsiveness; pulmonary embolism; pulmonary hypertension; sickle cell disease; sleep-disordered breathingACS, acute chest syndrome; AHI, apnea-hypopnea index; AHR, airway hyperresponsiveness; Dlco, diffusion capacity of the lung for carbon m
Role of neutralizing anti-murine interleukin-17A monoclonal antibody on chronic ozone-induced airway inflammation in mice
Keywords: AHR، پاسخگویی هوایی; COPD, chronic obstructive pulmonary disease; AHR, airway hyperresponsiveness; BAL, bronchoalveolar lavage; IFN-γ, interferon-γ; IL, interleukin; mAb, monoclonal antibody; mRNA, messenger ribonucleic acid; PBS, phosphate-buffered saline; RT-PCR, reverse tr
Secretory leukocyte protease inhibitor (SLPI), a multifunctional protein in the host defense response
Keywords: AHR، پاسخگویی هوایی; AHR, airway hyperresponsiveness; ALS, amyotrophic lateral sclerosis; CHIP, chromatin immunoprecipitation; CNS, central nervous system; COX, cyclooxygenase; HMG-1, high-mobility group 1; HSV, herpes simplex virus; ECM, extracellular matrix; IGFBP-3, insuli
Semaphorin 7A plays a critical role in IgE-mediated airway inflammation in mice
Keywords: AHR، پاسخگویی هوایی; AHR, airway hyperresponsiveness; BALF, bronchoalveolar lavage fluid; OVA, ovalbumin; SEMA7A, semaphorin 7ASemaphorin 7A; Plexin C1; Asthma; IgE; Neutrophil; Airway hyperresponsiveness
Reversal of IL-13-induced inflammation and Ca2+ sensitivity by resolvin and MAG-DHA in association with ASA in human bronchi
Keywords: AHR، پاسخگویی هوایی; AHR, airway hyperresponsiveness; HB, human bronchi; BSM, bronchial smooth muscle; ASA, acetylsalicylic acid; MAG-EPA, eicosapentaenoic acid monoacylglyceride; PUFA, polyunsaturated fatty acid; TNFα, tumor necrosis factor alpha; RvD1, 17S,8R,17S-trihydroxy
Genetic variation influences immune responses in sensitive rats following exposure to TiO2 nanoparticles
Keywords: AHR، پاسخگویی هوایی; AHR, airway hyperresponsiveness; BALF, bronchoalveolar lavage fluid; BN, Brown Norwegian; CRS, respiratory compliance; DA, Dark Aguoti; ENMs, engineered nanomaterials; G, tissue resistance; H, tissue elastance; MCh, methacholine; MMAD, mass median aerodyn
BuShenYiQi Formula strengthens Th1 response and suppresses Th2-Th17 responses in RSV-induced asthma exacerbated mice
Keywords: AHR، پاسخگویی هوایی; BSYQF, BuShenYiQi Formula; OVA, ovalbumin; RSV, respiratory syncytial virus; AHR, airway hyperresponsiveness; BALF, bronchoalveolar lavage fluid; IgE, immunoglobulin E; IL, interleukin; IFN-γ, interferon-γ; CAM, complementary and alternative medicine; TCM
Difference in time-course of improvement in asthma control measures between budesonide and budesonide/formoterol
Keywords: AHR، پاسخگویی هوایی; Airflow limitation; Airway hyperresponsiveness; Airway inflammation; Asthma Control Questionnaire; Exhaled nitric oxideACQ, Asthma Control Questionnaire; AHR, Airway hyperresponsiveness; BUD, Budesonide; FENO, Exhaled nitric oxide fraction; FM, Formoterol
The interleukin-4 − 589C/T polymorphism and the risk of asthma: A meta-analysis including 7345 cases and 7819 controls
Keywords: AHR، پاسخگویی هوایی; AHR, airway hyperresponsiveness; IL-4, interleukin-4; OR, odds ratio; CI, confidence interval; HWE, Hardy–Weinberg equilibrium; SNP, single nucleotide polymorphismAsthma; Interleukin-4; Meta-analysis; Polymorphism
Locally administered prostaglandin E2 prevents aeroallergen-induced airway sensitization in mice through immunomodulatory mechanisms
Keywords: AHR، پاسخگویی هوایی; PGE2, prostaglandin E2; HDM, house dust mite; pDC, plasmacytoid DC; mDC, myeloid DC; OPN, osteopontin; AHR, airway hyperresponsiveness; MC, mast cell; mMCP-1, mouse mast cell protease-1; WBP, whole body plethysmographyAeroallergen sensitization; Immunomod
IgE production in CD40/CD40L cross-talk of B and mast cells and mediator release via TGase 2 in mouse allergic asthma
Keywords: AHR، پاسخگویی هوایی; AHR, Airway hyperresponsiveness; BAL, Bronchoalveolar lavage; BMMCs, Bone marrow-derived mast cells; MCh, Methacholine; MMPs, Matrix metalloproteinases; PAS, Periodic acid-Schiff; PLA2, Phospholipase A2; PCA, Passive cutaneous anaphylaxis; TLR, Toll like
Bronchial epithelium as a target for innovative treatments in asthma
Keywords: AHR، پاسخگویی هوایی; Asthma; Epithelial cells; Airways; Treatment; Structural changesAch, Acetylcholine; AHR, Airway hyperresponsiveness; ASM, Airway smooth muscle; BAL, Bronchoalveolar lavage; BEC, Bronchial epithelial cell; CF, Cystic fibrosis; CFTR, Cystic fibrosis transme
The attenuation of cockroach allergy by DNA vaccine encoding cockroach allergen Bla g 2
Keywords: AHR، پاسخگویی هوایی; AAI, allergic airway inflammation; AHR, airway hyperresponsiveness; IFN-γ, interferon-γ; IL, interleukin; PBS, phosphate-buffered saline; rBla g 2, recombinant Bla g 2DNA vaccination; Cockroach allergens; T-helper cytokines; Allergy; Asthma
Drug development for severe asthma: What are the metrics?
Keywords: AHR، پاسخگویی هوایی; ACT, Asthma Control Test; AHR, Airway hyperresponsiveness; AMP, Adenosine monophosphate; AQLQ, Asthma Quality of Life Questionnaire; BHR, Bronchial hyperresponsiveness; COPD, Chronic obstructive pulmonary disease; FEV1, Forced expiratory volume in one sec
Increased immunosuppressive function of CD4+CD25+Foxp3+GITR+ T regulatory cells from NFATc2(−/−) mice controls allergen-induced experimental asthma
Keywords: AHR، پاسخگویی هوایی; AHR, airway hyperresponsiveness; BAL, bronchoalveolar lavage; BALF, BAL fluid; MCh, methacholine; N, normal (concentration of ionizable groups); qPCR, quantitative real-time polymerase chain reaction; Ri, airway resistance; t test, Student's t testCD4+CD2
Vitamin D deficiency decreases the expression of VDR and prohibitin in the lungs of mice with allergic airway inflammation
Keywords: AHR، پاسخگویی هوایی; AHR, Airway hyperresponsiveness; HBSMC, Human bronchial smooth muscle cell; PHB, Prohibitin; TNF-α, Tumor necrosis factor-α; VDR, Vitamin D receptorAllergic airway inflammation; Asthma; Human bronchial smooth cells; Inflammation; Prohibitin; TNF-α; Vitami
Establishment and characterization of a murine model for allergic asthma using allergen-specific IgE monoclonal antibody to study pathological roles of IgE
Keywords: AHR، پاسخگویی هوایی; sRaw, specific airway resistance; AHR, airway hyperresponsiveness; BALF, bronchoalveolar lavage fluid; MCh, methacholine; PAS, periodic acid-SchiffIgE; Monoclonal antibody; Early asthmatic response; Late asthmatic response; Airway hyperresponsiveness; Air
IL-13 suppresses double-stranded RNA-induced IFN-λ production in lung cells
Keywords: AHR، پاسخگویی هوایی; AHR, airway hyperresponsiveness; ssRNA, single-stranded RNA; dsRNA, double-stranded RNA; RIG-I, retinoic acid inducible-gene I; MDA5, melanoma differentiation-associated gene-5; IPS-1, interferon β promoter stimulator; TRIF, TIR-domain-containing adapter-
The role of the NLRP3 Inflammasome in the pathogenesis of airway disease
Keywords: AHR، پاسخگویی هوایی; AHR, airway hyperresponsiveness; ASC, apoptosis-associated speck-like protein containing a CARD; ATP, adenosine triphosphate; COPD, Chronic Obstructive Pulmonary Disease; CS, cigarette smoke; DAMP, danger associated molecular pattern; HDM, house dust mite
The NKT cell ligand αgalactosylceramide suppresses allergic airway inflammation by induction of a Th1 response
Keywords: AHR، پاسخگویی هوایی; AHR, airway hyperresponsiveness; alum, aluminium hydroxide; αGalCerMPEG, pegylated αgalactosylceramide; BAL, bronchoalveolar lavage; iDC, immature dendritic cells; IFN, interferon; i.n., intranasal; i.p., intraperitoneally; IL, interleukin; NKT, natural k
Monoclonal antibodies for the treatment of asthma
Keywords: AHR، پاسخگویی هوایی; Ig, immunoglobulin; IL, interleukin; TNF, tumor necrosis factor; CCR, CC chemokine receptor; CD, cluster of designation; TSLP, thymic stromal lymphopoietin; AHR, airway hyperresponsiveness; mAb, monoclonal antibody; Th, T helper; FcεRI, high affinity IgE
Interleukin-4 upregulates RhoA protein via an activation of STAT6 in cultured human bronchial smooth muscle cells
Keywords: AHR، پاسخگویی هوایی; BSM, bronchial smooth muscle; AHR, airway hyperresponsiveness; MLC, myosin light chain; IL, interleukin; STAT, signal transducer and activator of transcription; hEGF, human epidermal growth factor; hFGF-b, human fibroblast growth factor-basic; GAPDH, glyc
Cyclic adenosine monophosphate induces plasminogen activator inhibitor-1 expression in human mast cells
Keywords: AHR، پاسخگویی هوایی; AC, adenylate cyclase; AHR, airway hyperresponsiveness; cAMP, cyclic adenosine monophosphate; CRE, cAMP-response element; CREB, CRE-binding protein, db-cAMP, dibutyryl cAMP; db-cAMP, dibutyryl cAMP; DDA, 2′,5′-dideoxyadenosine; DN, dominant negative; EMSA
The proximal STAT6 and NF-κB sites are responsible for IL-13- and TNF-α-induced RhoA transcriptions in human bronchial smooth muscle cells
Keywords: AHR، پاسخگویی هوایی; BSM, bronchial smooth muscle; IL, interleukin; TNF, tumor necrosis factor; STAT, signal transducer and activator of transcription; NF-κB, nuclear factor κB; AHR, airway hyperresponsiveness; hBSMCs, human bronchial smooth muscle cells; IKK, IκB kinase; siR
Ethanol extracts of Saururus chinensis suppress ovalbumin-sensitization airway inflammation
Keywords: AHR، پاسخگویی هوایی; ESC, ethanol extract of Saururus chinensis; OVA, ovalbumin; AHR, airway hyperresponsiveness; BALF, bronchoalveolar lavage fluid; p.o., per oral; i.p., intraperitoneal; Th2 cytokine, T helper 2 cytokine; COX-2, cyclooxygenases-2; 5-LOX, 5-lipoxygenases; PB
Development of novel microarray methodology for the study of mutations in the SERPINA1 and ADRB2 genes—Their association with Obstructive Pulmonary Disease and Disseminated Bronchiectasis in Greek patients
Keywords: AHR، پاسخگویی هوایی; SERPINA1, Serine Protease Inhibitor A1; ADRB2, β2-adrenoceptor; AHR, airway hyperresponsiveness; PCR, polymerase chain reaction; SNP, single nucleotide polymorphisms; COPD, Chronic Obstructive Pulmonary Disease; DB, Disseminated BronchiectasisSERPINA1 ADR
Beneficial effects of high dose of L-arginine on airway hyperresponsiveness and airway inflammation in a murine model of asthma
Keywords: AHR، پاسخگویی هوایی; Allergic airway inflammation; arginase; L-arginine; endothelial nitric oxide synthase; exhaled nitric oxideAAI, Allergic airway inflammation; ADMA, Asymmetric dimethyl arginine; AHR, Airway hyperresponsiveness; BAL, Bronchoalveolar lavage; cGMP, Cyclic gu
Organ-specific eosinophilic disorders of the skin, lung, and gastrointestinal tract
Keywords: AHR، پاسخگویی هوایی; Asthma; cutaneous; dermatitis; eosinophilia; esophagitis; intestine; lung; respiratory; skinABPA, Allergic bronchopulmonary aspergillosis; AD, Atopic dermatitis; AHR, Airway hyperresponsiveness; BP, Bullous pemphigoid; CSS, Churg-Strauss syndrome; DRESS,
Mast cell degranulation is induced by A549 airway epithelial cell infected with respiratory syncytial virus
Keywords: AHR، پاسخگویی هوایی; Ag, antigen; AHR, airway hyperresponsiveness; CX3CL1, chemokine (C-X3-C motif) ligand 1; CX3CR1, chemokine (C-X3-C motif) receptor 1; DMEM, Dulbecco's modified Eagle's medium; FCS, fetal calf serum; G protein, attachment glycoprotein; Ig, immunoglobulin;
Advances in mechanisms of asthma, allergy, and immunology in 2008
Keywords: AHR، پاسخگویی هوایی; ADAM, A disintegrin and metalloprotease; AHR, Airway hyperresponsiveness; FIP1L1-PDGFRA, Fip1-like1–platelet-derived growth factor receptor α-chain; MMCP, Mouse mast cell protease; PI-3K, Phospatidylinostol-3-phosphate kinase; Siglec, Sialic acid–binding
Dietary supplementation of ω-3 fatty acid-containing fish oil suppresses F2-isoprostanes but enhances inflammatory cytokine response in a mouse model of ovalbumin-induced allergic lung inflammation
Keywords: AHR، پاسخگویی هوایی; AA, arachidonic acid; AHR, airway hyperresponsiveness; BHT, butylated hydroxyl toluene; BSTFA, N,O-bis(trimethylsilyl)-trifluoroacetamide; CID, collision-induced dissociation; COX, cyclooxygenase; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; ESI
Adenosine deaminase and adenosine receptor polymorphisms in aspirin-intolerant asthma
Keywords: AHR، پاسخگویی هوایی; Aspirin-intolerant asthma; Adenosine receptors; Adenosine deaminase; PolymorphismADA, adenosine deaminase; AHR, airway hyperresponsiveness; AIA, aspirin-intolerant asthma; AMP, adenosine monophosphate; ATA, aspirin-tolerant asthma; COX, cyclooxygenase FEV
Gene-environment interactions in asthma
Keywords: AHR، پاسخگویی هوایی; Asthma; genes; environment; interactionsADBR2, α2-Adrenergic receptor; AHR, Airway hyperresponsiveness; aOR, Adjusted odds ratio; ETS, Environmental tobacco smoke; GST, Glutathione S transferase; MIT, Mean interaction test; NOD, Nucleotide-binding oligome
Analytical validation of a highly sensitive microparticle-based immunoassay for the quantitation of IL-13 in human serum using the Erenna® immunoassay system
Keywords: AHR، پاسخگویی هوایی; IL-13, Interleukin-13; PD, pharmacodynamic; AHR, airway hyperresponsiveness; BAL, bronchial lavage fluid; LoD, limit of detection; LLoQ, lower limit of quantification; ULoQ, upper limit of quantification; CV, coefficient of variance; SD, standard deviatio
The role of the extracellular matrix and specific growth factors in the regulation of inflammation and remodelling in asthma
Keywords: AHR، پاسخگویی هوایی; AHR, airway hyperresponsiveness; ASM, airway smooth muscle; BAL, bronchial lavage fluid; BDNF, brain-derived neurotrophic factor; CCN, cysteine-rich 61 (CYR61), CTGF, nephroblastoma overexpressed (NOV); CTGF, connective tissue growth factor; ECM, extracel
Rapid Effect of Inhaled Ciclesonide in Asthma : A Randomized, Placebo-Controlled Study
Keywords: AHR، پاسخگویی هوایی; airway hyperresponsiveness; asthma; ciclesonide; nitric oxide; sputumAE, adverse event; AHR, airway hyperresponsiveness; AMP, adenosine monophosphate; CCL2, chemokine (C-C motif) ligand 2; CI, confidence interval; DTT, dithiothreitol; ICS, inhaled cortico
Increased sputum and bronchial biopsy IL-13 expression in severe asthma
Keywords: AHR، پاسخگویی هوایی; Severe asthma; IL-13; sputum; bronchus; airway smooth muscle; eosinophiliaACQ, Juniper Asthma Control Questionnaire; AHR, Airway hyperresponsiveness; ASM, Airway smooth muscle; GINA, Global Initiative for Asthma
Cell types involved in allergic asthma and their use in in vitro models to assess respiratory sensitization
Keywords: AHR، پاسخگویی هوایی; 3D, three-dimensional; Ad12SV40, adenovirus 12-simian virus 40 hybrid virus; AHR, airway hyperresponsiveness; APCs, antigen-presenting cells; ASM, airway smooth muscle; ATCC, American Type Culture Collection; BAL, bronchoalveolar lavage; BECs, bronchial e
Understanding the mechanisms of viral induced asthma: New therapeutic directions
Keywords: AHR، پاسخگویی هوایی; AAD, allergic airways disease; AHR, airway hyperresponsiveness; APC, antigen-presenting cell; ASM, airway smooth muscle; BALF, broncho-alveolar lavage fluid; BEC, bronchoepithelial cell; bFGF, basic fibroblast growth factor; CAM, Cellular adhesion molecul
Sleep apnea is associated with bronchial inflammation and continuous positive airway pressure–induced airway hyperresponsiveness
Keywords: AHR، پاسخگویی هوایی; Obstructive sleep apnea syndrome; bronchial inflammation; neutrophil; IL-8; NO exhalation; airway hyperresponsiveness; continuous positive airway pressureAHI, Apnea hypopnea index; AHR, Airway hyperresponsiveness; COPD, Chronic obstructive pulmonary disea
Blocking IL-25 prevents airway hyperresponsiveness in allergic asthma
Keywords: AHR، پاسخگویی هوایی; IL-25; airway hyperresponsiveness; allergic inflammation; type 2 immunity; IL-13; IL-175-HT, 5-Hydroxytrytamine; AHR, Airway hyperresponsiveness; BAL, Bronchoalveolar lavage; IL-25R, IL-25 receptor; OVA, Ovalbumin; rIL-25, Recombinant IL-25; rmIL-25, Reco
Expression of activated FcγRII discriminates between multiple granulocyte-priming phenotypes in peripheral blood of allergic asthmatic subjects
Keywords: AHR، پاسخگویی هوایی; Priming; allergen challenge; neutrophils; eosinophils; allergic asthma; gene expression; peripheral bloodαm, α-Chain of Mac-1; AHR, Airway hyperresponsiveness; EAR, Early asthmatic response; FITC, Fluorescein isothiocyanate; fMLF, N-formyl-methionyl-leucy
Anthocyanins inhibit airway inflammation and hyperresponsiveness in a murine asthma model
Keywords: AHR، پاسخگویی هوایی; AHR, airway hyperresponsiveness; BAL, bronchoalveolar lavage; C3G, cyanidin-3-O-glucoside; CFA, complete Freund’s adjuvant; CINC-1, cytokine-induced neutrophil chemoattractant-1; COX-2, cyclooxygenase-2; H&E, haematoxylin and eosin; IL, interleukin; iNOS,
The treatment of asthma in children: Inhaled corticosteroids
Keywords: AHR، پاسخگویی هوایی; Inhaled corticosteroids; Childhood asthma; Asthmatic inflammation; Efficacy of inhaled corticosteroids; Safety of inhaled corticosteroidsTh, T-helper; AHR, airway hyperresponsiveness; ICS, inhaled corticosteroids; SCS, systemic corticosteroids; BDP, beclo