دانلود مقالات ISI درباره Akr + ترجمه فارسی

شناسایی آنزیم هایی که متابولیسم دانترولین را در کبد انسان انجام می دهند: یک راه برای کشف علت آسیب کبدی

Identification of enzymes responsible for dantrolene metabolism in the human liver: A clue to uncover the cause of liver injury

Keywords: AKR; aldo-keto reductase; AOX1; aldehyde oxidase 1; 11β-HSD; 11β-hydroxysteroid dehydrogenase; CBR; carbonyl reductase; CYP; cytochrome P450; EDTA; ethylenediamine-N,N,N',N'-tetraacetic acid; G-6-P; glucose-6-phosphate; G-6-PDH; glucose-6-phosphate

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

بیوسنتز داخل آندروژن، متابولیسم و ​​عمل مجددا بررسی می شود

Intracrine androgen biosynthesis, metabolism and action revisited

Keywords: Androgens; Intracrinology; Steroid biosynthesis; Hormone-dependent cancer; Testosterone; 11-oxygenated androgens; 11KA4; 11-keto-androstenedione; 11KDHT; 11-keto-5α-dihydrotestosterone; 11KT; 11-keto-testosterone; 11OHA4; 11β-hydroxy-androstenedione; 11

دانلود رایگان متن کامل مقاله ISI 69 صفحه سال انتشار : 2018 سفارش ترجمه

متابولیسم تدریجی اسید تیواپروفنیک توسط کبد انسان و آنزیم های کربونیل نوترکیب آنزیم

Reductive metabolism of tiaprofenic acid by the human liver and recombinant carbonyl reducing enzymes

Keywords: Tiaprofenic acid; Carbonyl reducing enzymes (CREs); AKR; Short-chain dehydrogenase/reductase; Carbonyl reductase; Reductive drug metabolism;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2017 سفارش ترجمه

برنامه های کاربردی غربالگری مجازی در تحقیقات کمبود زنجیره ای دهیدروژناز / ردوکتاز

Virtual screening applications in short-chain dehydrogenase/reductase research

Keywords: 3-BC; 3-benzylidene camphor; 4-MBC; 4-methylbenzylidene camphor; Aβ; amyloid-β; ABAD; Aβ-binding alcohol dehydrogenase; AD; Alzheimer's disease; AI; aromatase inhibitor; AKR; aldo-keto reductase; AME; apparent mineralocorticoid excess; AR; androgen r

دانلود رایگان متن کامل مقاله ISI 67 صفحه سال انتشار : 2017 سفارش ترجمه

پروستاگلاندین سنتاز: مشخصه های مولکولی و دخالت در پروتئاز گلاندین های بیوسنتز

Prostaglandin synthases: Molecular characterization and involvement in prostaglandin biosynthesis

Keywords: AA; arachidonic acid; AKR; aldo-keto reductase; AOS; allene oxide synthase; CX; carbon numbers; COX; cyclooxygenase; cPGES; cytosolic PGE synthase; cPLA2; cytosolic phospholipase A2; CYP; cytochrome P450; DGLA; dihomo-γ-linolenic acid; DP; prostaglandin

دانلود رایگان متن کامل مقاله ISI 75 صفحه سال انتشار : 2017 سفارش ترجمه

یک مطالعه فانتوم و یک تجزیه و تحلیل بالینی یکپارچه برای بررسی تاثیر فناوری پردازش تصویر جدید بر کیفیت دوز و کیفیت تصویر در هنگام امبولیسازی کبد

A Phantom Study and a Retrospective Clinical Analysis to Investigate the Impact of a New Image Processing Technology on Radiation Dose and Image Quality during Hepatic Embolization

Keywords: AERLC; automatic exposure rate control logic; AKR; air kerma rate; CAK; cumulative air kerma; CI; confidence interval; KAP; kerma-area product;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

تحمل استرس به جو ژن ترانسژنیک تجمع ردوکتاز یونجه آلدو در سیتوپلاسم و کلرپلاست

Stress tolerance of transgenic barley accumulating the alfalfa aldose reductase in the cytoplasm and the chloroplast

Keywords: Barley; Hordeum vulgare; Poaceae; Abiotic stress tolerance; Transgenic barley; Aldose reductase; DsRed/GFP fluorescent proteins; AKR; aldo-keto reductase; cpMsALR; MsALR protein targeted to the chloroplast; DsRed; red fluorescent protein from Discosoma sp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

نقش آنزیم های کربنیل کاهش دهنده در متابولیسم اکروکاربازپین در شرایط آزمایشگاهی در انسان

The role of carbonyl reducing enzymes in oxcarbazepine in vitro metabolism in man

Keywords: AKR; aldo-keto reductase; CBZ-E; carbamazepine 10,11-epoxide; Cmax; mean maximum level; CLint; internal clearance; DHD; 10,11-dihydro-10,11-dihydroxy-carbamazepine; MHD; 10,11-dihydro-10-hydroxy-carbamazepine; SDR; short-chain dehydrogenase/reductase; O

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

تجزیه و تحلیل ژنتیکی غلظت گلوتاتیون بافت و تعادل بازدارندگی

Genetic analysis of tissue glutathione concentrations and redox balance

Keywords: 129; 129S1/SvImJ; A; A/J; AKR; AKR/J; ALR; ALR/J; B6; C57BL/6 J; B10; C57BL/10 J; BALB; BALB/cByJ; BLKS; C57BLKS/J; BTBR; BTBR T+ Itpr3tf/J; C3H; C3H/HeJ; C57L; C57L/J; CAST; CAST/EiJ; CBA; CBA/J; D1; DBA/1 J; D2; DBA/2 J; DTPA; diethylenetriaminepent

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

سنتز نوین مشتقات نیترو-کینوکسالینون به عنوان مهار کننده های آلوده ردوکتاز

Novel synthesis of nitro-quinoxalinone derivatives as aldose reductase inhibitors

Keywords: ALR2; aldose reductase; AKR; aldo-keto reductase; NADPH; β-nicotinamide adenine dinucleotide phosphate reduced form; ARIs; aldose reductase inhibitors; SAR; structure-activity relationship; Quinoxalinone derivatives; Aldose reductase inhibitors; Struct

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

چشم انداز پروتئومیک جنین زایی سوپروا سوکر

Proteomic perspective of Quercus suber somatic embryogenesis

Keywords: AA; Ascorbic acid; AFR; Ascorbate free radical; AKR; Aldo keto reductase; CAD; Cinnamyl alcohol dehydrogenase; CSE; Cotyledonar somatic embryos; DHA; Dehydroascorbate (synonym: dehydroascorbic acid); GAPDH; Glyceraldehyde-3-phosphate dehydrogenase; Hsp; H

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2013 سفارش ترجمه

متابولیسم در شرایط آزمایشگاهی اسید fenofibric توسط آنزیم های کاهش دهنده کربونیل

In vitro metabolism of fenofibric acid by carbonyl reducing enzymes

Keywords: AKR; Carbonyl reducing enzymes; Carbonyl reductase; Fenofibric acid; Reductive drug metabolism; Short-chain dehydrogenase/reductaseAKR, aldo-keto reductase; CLint, internal clearance; CREs, carbonyl reducing enzymes; SDR, short-chain dehydrogenase/reducta

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Essential Intracrine Androgenic Action in Lung Development for Both Sexes

Keywords: 5α-DH-DOC; 5α-dihydro-deoxycorticosterone; AKR; aldo-keto reductase; DHT; dihydrotestosterone; DOC; deoxycorticosterone; GD; gestation day; HSD; hydroxysteroid dehydrogenase; NMR; nuclear magnetic resonance; PND; postnatal day; androgens; bronchopulmona

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Significance of A-to-I RNA editing of transcripts modulating pharmacokinetics and pharmacodynamics

Keywords: ABC; ATP-binding cassette transporter; ADAR; adenosine deaminase acting on RNA; ADH; alcohol dehydrogenase; AhR; aryl hydrocarbon receptor; AKR; aldo-keto reductase; ALS; amyotrophic lateral sclerosis; AZIN1; antizyme inhibitor 1; AMPA; α-amino-3-hydroxy

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Facilitation of 9,10-phenanthrenequinone-elicited neuroblastoma cell apoptosis by NAD(P)H:quinone oxidoreductase 1

Keywords: 9,10-Phenanthrenequinone; Neuroblastoma cell; Apoptosis; Reactive oxygen species; Antioxidant property; NAD(P)H:quinone oxidoreductase 1; AKR; aldo-keto reductase; AMC; 7-amido-4-methylcoumarin; ATM; ataxia telangiectasia mutated kinase; BSO; dl-buthionin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

High CD44 expression mediates p62-associated NFE2L2/NRF2 activation in breast cancer stem cell-like cells: Implications for cancer stem cell resistance

Keywords: AKR; aldo-keto reductase; ARE; antioxidant response element; CD44; cluster of differentiation 44; CSC; cancer stem cell; GCLC; glutamate-cysteine ligase catalytic subunit; GPX; glutathione peroxidase; GSH; glutathione; HO-1; heme oxygenase-1; HA; hyaluron

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Roscovitine and purvalanol A effectively reverse anthracycline resistance mediated by the activity of aldo-keto reductase 1C3 (AKR1C3): A promising therapeutic target for cancer treatment

Keywords: AKR; aldo-keto reductase; CDK; cyclin-dependent kinase; CI; combination index; Dau; daunorubicin; Dau-ol; daunorubicinol; DOX; doxorubicin; DMSO; dimethyl sulfoxide; Fa; fraction affected; HCT116-AKR1C3; cells transfected with pCI_AKR1C3; HCT116-EV; cells

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Activation of Nrf2 attenuates carbonyl stress induced by methylglyoxal in human neuroblastoma cells: Increase in GSH levels is a critical event for the detoxification mechanism

Keywords: Nrf2 activator; CDDO-Im; Carnosic acid; Neuroblastoma; Carbonyl stress; Methylglyoxal; GSH synthesis; AGEs; advanced glycation end products; AKR; aldo-keto reductase; BSO; buthionine sulfoximine; CA; carnosic acid; CEL; Nε-(1-carboxyethyl)lysine; CDDO-Im

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Structural basis for the inhibition of AKR1B10 by the C3 brominated TTNPB derivative UVI2008

Keywords: Cancer; Enzyme inhibitor; Psoriasis; RAR/RXR agonist; Retinoic acid; Skin disease; AR; Aldose Reductase; AKR; Aldo-Keto Reductase; AKR1B10; AKR family member 1B10; AKR1B15; AKR family member 1B15; AKR1A1; AKR family member 1A1 or aldehyde reductase; ARIs;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Human carbonyl reductase 1 participating in intestinal first-pass drug metabolism is inhibited by fatty acids and acyl-CoAs

Keywords: CBR; carbonyl reductase; SDR; short-chain dehydrogenase/reductase; CYP; cytochrome P450; AKR; aldo-keto reductase; DOX; doxorubicin; FA; fatty acid; ONE; 4-oxo-2-nonenal; 13h; 8-hydroxy-2-imino-2H-chromene-3-carboxylic acid (2-chlorophenyl)amide; DHRS4; d

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Research articleAldo-keto reductase-1 (AKR1) protect cellular enzymes from salt stress by detoxifying reactive cytotoxic compounds

Keywords: Salinity; AKR; Protein carbonyls; Antioxidant; ROS; Proline; Cytotoxic compounds;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Degradation of doxorubicin to non-toxic metabolites using Fe-Ni bimetallic nanoparticles

Keywords: Doxorubicin; Fe-Ni nanoparticles; Degradation; AKR; Anticancer activity; Cheminformatics;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

4-Hydroxynonenal metabolites and adducts in pre-carcinogenic conditions and cancer

Keywords: ABC transporters; ATP-binding cassette transporters; AhR; aryl hydrocarbon receptor; AKR; aldo-keto reductase; Akt; protein kinase B; ALDH; aldehyde dehydrogenase; AOR; alkenal/one oxidoreductase; AP-1; activator Protein-1; AR; aldose reductase; ARE/EpRE;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Proteome analysis reveals an energy-dependent central process for Populus × canadensis seed germination

Keywords: 2-D; two-dimensional; 26SP; 26S proteasome; ABA; abscisic acid; AKR; aldo-keto reductase; AlaAT; alanine aminotransferase; AspAT; aspartate aminotransferase; CBB; Coomassie brilliant blue R-250; CHX; cycloheximide; CysPI; cysteine proteinase inhibitor; DX

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Characterization of AKR1B16, a novel mouse aldo-keto reductase

Keywords: Aldose reductase inhibitor; Enzyme kinetics; Gene orthology; Retinaldehyde reductase; Steroid oxidoreductase; Subcellular localization; Δ4-Ae; androst-4-ene-3,17-dione; AKR; aldo-keto reductase; AKR1B16; AKR family member 1B16; ARI; aldose reductase inhi

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Role of farnesoid X receptor in establishment of ontogeny of phase-I drug metabolizing enzyme genes in mouse liver

Keywords: ADH; alcohol dehydrogenase; AKR; aldoketo reductase; ALDH; aldehyde dehydrogenase; CES; carboxylesterase (Ces); DPYD; dihydropyrimidine dehydrogenase; EPHX; epoxide hydrolase; FMO; flavin monooxygenases, Farnesoid X receptor (FXR); NQO; quinone oxidoreduc

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Structural characterization of an aldo-keto reductase (AKR2E5) from the silkworm Bombyx mori

Keywords: Protein crystal structure; Enzyme specificity; NADPH; Lepidoptera; AKR; aldo-keto reductase; DLG; DL-glyceraldehyde; PCR; polymerase chain reaction; RT-PCR; reverse transcriptase PCR; SDS-PAGE; sodium dodecyl sulfate polyacrylamide gel electrophoresis; TI

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of aldo-keto reductase family 1 member B10 by unsaturated fatty acids

Keywords: Aldo-keto reductase; AKR1B10; cis-Unsaturated fatty acids; Cancer; Inhibitory selectivity; AKR; aldo-keto reductase; ALA; α-linolenic acid; ARA; arachidonic acid; DHA; docosahexaenoic acid; EPA; eicosapentaenoic acid; LA; linoleic acid; ONE; 4-oxo-2-none

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Genetic engineering of Bacillus megaterium for high-yield production of the major teleost progestogens 17α,20β-di- and 17α,20β,21α-trihydroxy-4-pregnen-3-one

Keywords: AKR; aldo-keto reductase; 17OH-P; 17α-hydroxyprogesterone; 17α,20αDiOH-P; 17α,20α-dihydroxy-4-pregnen-3-one; 17α,20βDiOH-P; 17α,20β-dihydroxy-4-pregnen-3-one; 20βOH-RSS; 17α,20α,21α-trihydroxy-4-pregnen-3-one; DOC; 11-deoxycorticosterone; Fab

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

MicroRNAs related to androgen metabolism and polycystic ovary syndrome

Keywords: Polycystic ovary syndrome; MicroRNA; Androgens; DHEA; DHEAS; Ovarian steroid metabolism; Biomarker; DHEA; dehydroepiandrosterone; DHEAS; dehydroepiandrosterone sulfate; PCOS; polycystic ovary syndrome; T2D; type 2 diabetes mellitus; CYP; Cytochrome P450;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of a determinant for strict NADP(H)-specificity and high sensitivity to mixed-type steroid inhibitor of rabbit aldo-keto reductase 1C33 by site-directed mutagenesis

Keywords: 5αAD; 5α-androstane-3α,17β-diol; AKR; aldo-keto reductase; DOC; deoxycorticosterone; HSD; hydroxysteroid dehydrogenase; P3A; pyridine-3-aldehyde; Aldo-keto reductase; Bile acid synthesis; Coenzyme specificity determinant; Conformational change; De

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Transgenic barley expressing the Arabidopsis AKR4C9 aldo-keto reductase enzyme exhibits enhanced freezing tolerance and regenerative capacity

Keywords: AKR; aldo-keto reductase; 4-HNE; 4-hydroxynonenal; HPLC-RID; high performance liquid chromatography with refractive index detector; MDA; malondialdehyde; ROS; reactive oxygen species; SOD; superoxide dismutase; WT; wild type; Frost tolerance; Sugar alcoho

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Aldo-keto reductase 7A5 (AKR7A5) attenuates oxidative stress and reactive aldehyde toxicity in V79-4 cells

Keywords: AKR; aldo-keto reductase; ROS; reactive oxygen species; DCFH/DA; 2′7′-dichlorodihydrofluorescein diacetate; AFB1; aflatoxin B1; CDNB; 1-chloro-2,4-dintrobenzene; MTT; 3-(4,5-dimethylthiazoyl-2-yl)-2,5-diphenyltetrazolium bromide; H2O2; hydrogen pero

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Investigations on the metabolic stability of cytosolic phospholipase A2α inhibitors with 1-indolylpropan-2-one structure

Keywords: cPLA2α; cytosolic phospholipase A2α; CYP450; cytochrome P450; SDR; short-chain dehydrogenase/reductase; AKR; aldo-keto-reductase; HPLC; high performance liquid chromatography; MS; mass spectrometry; ESI; electrospray ionization; NMR; nuclear magnetic

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Identification, characterization, and crystal structure of an aldo-keto reductase (AKR2E4) from the silkworm Bombyx mori

Keywords: Crystal structure; Enzyme specificity; NADH; NADPH; Lepidoptera; 3DE; 3-dehydroecdysone; AKR; aldo-keto reductase; DLG; dl-glyceraldehyde; GST; glutathione transferase; PCR; polymerase chain reaction; RT-PCR; reverse transcriptase PCR; SDS-PAGE; sodiu

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

ReviewClinical management of drug-drug interactions in HCV therapy: Challenges and solutions

Keywords: HCV; hepatitis C virus; DAAs; direct-acting antivirals; HIV; human immunodeficiency virus; SPCs; summary of product characteristics; Peg; polyethylene glycol; BID; twice daily; AKR; aldo-ketoreductases; P-gp; P-glycoprotein; AUC; area under the plasma con

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Trp266 determines the binding specificity of a porcine aflatoxin B1 aldehyde reductase for aflatoxin B1-dialdehyde

Keywords: AFB1; aflatoxin B1; AFG1; aflatoxin G1; AFAR; aflatoxin B1 aldehyde reductase; AKR; aldo-keto reductase; AFBO; AFB1 exo-8,9-epoxide; 2-CBA; 2-carboxybenzaldehyde; SSA; succinic semialdehyde; WT; wide-type; IPTG; isopropyl-β-d-thiogalactoside; HPLC; high

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Aldo-keto reductases mediate constitutive and inducible protection against aldehyde toxicity in human neuroblastoma SH-SY5Y cells

Keywords: AKR; aldo-keto reductases; CSF; cerebrospinal fluid; 4-HNE; 4-hydroxynonenal; RNAi; RNA interference; siRNA; small inhibitory RNA; t-BHQ; tert-butylhydroquinone; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; D3T; 3H-1,2-dithiole-3-t

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Rabbit 3-hydroxyhexobarbital dehydrogenase is a NADPH-preferring reductase with broad substrate specificity for ketosteroids, prostaglandin D2, and other endogenous and xenobiotic carbonyl compounds

Keywords: 3HB; 3-hydroxyhexobarbital; 3OB; 3-oxohexobarbital; 3HBD; 3-hydroxyhexobarbital dehydrogenase; AKR; aldo-keto reductase; HSD; hydroxysteroid dehydrogenase; PG; prostaglandin; TBE; 6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione; 4R-TBEH; 6-tert-butyl-2,3-e

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Reduced protein oxidation in Wistar rats supplemented with marine ω3 PUFAs

Keywords: 1/2-DE; one/two-dimensional gel electrophoresis; AKR; 3-α-hydroxysteroid dehydrogenase; ALA; α-linolenic acid; ARA; arachidonic acid; ASS; argininosuccinate synthetase; AST; aspartate aminotransferase; DHA; docosahexaenoic acid; DNPH; 2,4-dinitrophenylh

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Evaluation of the prostaglandin F synthase activity of human and bovine aldo-keto reductases: AKR1A1s complement AKR1B1s as potent PGF synthases

Keywords: AA; arachidonic acid; AKR; aldo-keto reductases; BLOTTO; fat-free dry milk in PBS-T; COX; cyclooxygenase; DD3; dihydrodiol dehydrogenase 3; IL-1β; interleukine-1 beta; PBS-T; PBS with Tween 20; PGs; prostaglandins; PGD2; prostaglandin D2; PGE2; prostagla

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Inducible protection of human astrocytoma 1321N1 cells against hydrogen peroxide and aldehyde toxicity by 7-hydroxycoumarin is associated with the upregulation of aldo-keto reductases

Keywords: AKR; aldo-keto reductase; 7-HC; 7-hydroxycoumarin; ALDH; aldehyde dehydrogenase; ROS; reactive oxygen species; CSF; cerebrospinal fluid; HNE; 4-hydroxy-trans-2-nonenal; AD; Alzheimer's disease; DCFH/DA; dichlorodihydrofluorescein diacetate; Carbonyl toxic

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Human aldo-keto reductase AKR7A2 protects against the cytotoxicity and mutagenicity of reactive aldehydes and lowers intracellular reactive oxygen species in hamster V79-4 cells

Keywords: AKR; aldo-keto reductase; SSA; succinic semialdehyde; CBA; carboxybenzaldehyde; IC50; inhibitory concentration of 50% the cells; HNE; 4-hydroxynonenal; MTT; 3-(4,5-dimethylthiazoyl-2-yl)-2,5-diphenyltetrazolium bromide; NQ; naphthoquinone; HGPRT; hypoxa

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

The effect of disease associated point mutations on 5β-reductase (AKR1D1) enzyme function

Keywords: 5β-reductase; AKR; Bile acid deficiency;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Vitamin C supplementation lowers urinary levels of 4-hydroperoxy-2-nonenal metabolites in humans

Keywords: AKR; aldo-keto reductase; ALDH; aldehyde dehydrogenase; BMI; body mass index; DHN; 1,4-dihydroxy-2(E)-nonene; GPx; glutathione peroxidase; GSH; glutathione; GST; glutathione S-transferase; HNA; 4-hydroxy-2(E)-nonenoic acid; HNE; 4-hydroxy-2(E)-nonenal; HP

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Structure-activity relations on [1-(3,5-difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl]phenylmethanone. The effect of methoxy substitution on aldose reductase inhibitory activity and selectivity

Keywords: AKR; aldoketoreductase; ALR1; aldehyde reductase; ALR2; aldose reductase; ARI; aldose reductase inhibitor; PKC; protein kinase C; rmsd; root-mean squared deviation; SDH; sorbitol dehydrogenase; Aldose and aldehyde reductase; ARI; Long-term diabetic compli

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Anthracyclines and their metabolism in human liver microsomes and the participation of the new microsomal carbonyl reductase

Keywords: SDR; short-chain dehydrogenyse/reductase; AKR; aldo-keto reductase; 11β-HSD1; 11β-hydroxysteroid dehydrogenase 1; ANT; anthracycline; DAUN; daunorubicin; DAUNOL; daunorubicinol; ADAUN; aglycone of daunorubicin; ADAUNOL; aglycone of daunorubicinol; DOX;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Glyoxalase in diabetes, obesity and related disorders

Keywords: AGE; advanced glycation endproducts; AKR; aldoketo reductase; BBGD; S-p-bromobenzylglutathione cyclopentyl diester; CEL; Nɛ-carboxyethyl-lysine; CMA; Nω-carboxymethylarginine; CML; Nɛ-carboxymethyl-lysine; CNV; copy number variation; CVD; cardiovascula

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Chromene-3-carboxamide derivatives discovered from virtual screening as potent inhibitors of the tumour maker, AKR1B10

Keywords: AKR; aldo-keto reductase; ALR; aldehyde reductase; AR; aldose reductase; FBS; fetal bovine serum; HNE; 4-hydroxy-2-nonenal; PHPC; (Z)-2-(phenylimino)-7-hydroxy-N-(pyridin-2-yl)-2H-chromene-3-carboxamide; AKR1B10; Aldose reductase-like protein; Aldose redu

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Liquid chromatography-mass spectrometry (LC-MS) of steroid hormone metabolites and its applications

Keywords: 3α-Diol-17G; 3α-hydroxy-5α-androstane-17β-glucuronide; 3β-Diol-17G; 3β-hydroxy-5α-androstane-17β-glucuronide; 3α-Diol-17S; 3α-hydroxy-5α-androstane-17β-sulfate; 3β-Diol-17S; 3β-hydroxy-5α-androstane-17β-sulfate; DHT; dihydrotestosterone; D

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه