دانلود مقالات ISI درباره آکت + ترجمه فارسی

Phase I clinical, pharmacokinetic, and pharmacodynamic study of the Akt-inhibitor triciribine phosphate monohydrate in patients with advanced hematologic malignancies

Keywords: آکت; Akt; Nucleoside analog; Triciribine; AML; Phase I clinical trial;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Role of glycogen synthase kinase-3β in ketamine-induced developmental neuroapoptosis in rats

Keywords: آکت; AKT; apoptosis; glycogen synthase kinase-3β; ketamine; lithium; protein kinase B;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Zinc chloride exposure increases heme oxygenase-1 expression in MDPC-23 odontoblast-like cells

Keywords: آکت; Akt; amino kinase terminal; DMSO; dimethyl sulfoxide; ERK; extracellular signal-regulated protein kinase; HO-1; heme oxygenase-1; JNK; c-Jun NH2-terminal kinase; MAPKs; mitogen-activated protein kinases; MK-2; MAPK-activated protein kinase-2; NF-κB; nucl

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Cholesterol induces cardiac hypertrophy by activating the AKT pathway

Keywords: آکت; IGF; insulin growth factor; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; PI3K; phosphatidylinositol-3-kinase; GPCR; G-protein-coupled receptor; mTOR; mammalian target of rapamycin; GSK3β; phospho-glycogen synthase k

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Relevance of signaling molecules for apoptosis induction on influenza A virus replication

Keywords: آکت; Akt; v-akt murine thymoma viral oncogene homolog 1; Apaf-1; apoptotic protease activating factor 1; Bax; Bcl-2-associated x protein; Bcl-2; B-cell lymphoma 2; BH; Bcl-2 homology; Caspases; cysteine-aspartic acid protease; DAP3; death-associated protein

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

ICAM-3 endows anticancer drug resistance against microtubule-damaging agents via activation of the ICAM-3-AKT/ERK-CREB-2 pathway and blockage of apoptosis

Keywords: آکت; ICAM-3; Akt; ERK; CREB-2; Drug resistance; Apoptosis; Paclitaxel; Vincristine;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Signals regulating necrosis of cardiomyoblast by BTG2/TIS21/PC3 via activation of GSK3β and opening of mitochondrial permeability transition pore in response to H2O2

Keywords: آکت; Necrosis; H9c2 cardiomyoblast; BTG2/TIS21/PC3 gene; Akt; Erk; Cyclophilin D;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Shock/Sepsis/Trauma/Critical CareTherapeutic hypothermia attenuates liver injury in polymicrobial sepsis model of rats via Akt survival pathway

Keywords: آکت; Therapeutic hypothermia; Sepsis; Liver injury; Akt;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway

Keywords: آکت; AKT; v-akt murine thymoma viral oncogene; CRC; colorectal cancer; FDR; false discovery rate; HECT; homologous to E6AP C terminus; KEGG; Kyoto Encyclopedia of Genes and Genomes; mut; mutated; NCBI; National Center for Biotechnology Information; PBS; phosph

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Proline-rich Akt substrate of 40-kDa contains a nuclear export signal

Keywords: آکت; PRAS40; Akt; Insulin action; Subcellular localization; Nuclear export signal;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

TOPK and PTEN participate in CHFR mediated mitotic checkpoint

Keywords: آکت; Chfr; PTEN; TOPK; E3 ligase; Akt; Mitosis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Thymoquinone attenuates liver fibrosis via PI3K and TLR4 signaling pathways in activated hepatic stellate cells

Keywords: آکت; Akt; serine/threonine kinase-protein kinase B; ALT; alanine aminotransferase; AST; aspartate aminotransferase; α-SMA; α-smooth muscle actin; c-FLIP; cellular FLIP; d-GlaN; d-galactosamine; ECM; extracellular matrix; HSCs; hepatic stellate cells; LPS; li

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

A dipeptide and an amino acid present in whey protein hydrolysate increase translocation of GLUT-4 to the plasma membrane in Wistar rats

Keywords: آکت; AMPK; 5′-AMP-activated protein kinase; Akt; protein kinase B; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CK; creatine kinase; GLUT-4; glucose transporter 4; LDH; lactate dehydrogenase; p85; PI 3 kinase p85 alpha; PM; plasmatic membr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Denbinobin induces human glioblastoma multiforme cell apoptosis through the IKKα-Akt-FKHR signaling cascade

Keywords: آکت; Denbinobin; Glioblastoma multiforme; Akt; IKK; FKHR;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Akt kinase targets the association of CBP with histone H3 to regulate the acetylation of lysine K18

Keywords: آکت; CBP; Acetylation; Akt;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Glycyrrhizic acid and 18β-glycyrrhetinic acid recover glucocorticoid resistance via PI3K-induced AP1, CRE and NFAT activation

Keywords: آکت; Glycyrrhizic acid; 18β-Glycyrrhetinic acid; Glucocorticoid receptor; Phosphoinositide 3-kinase; Glucocorticoid resistance; 18βGA; 18β-glycyrrhetinic acid; Akt; protein kinase B; AP1; activator protein 1; COPD; chronic obstructive pulmonary disease; CRE

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Fisetin regulates obesity by targeting mTORC1 signaling

Keywords: آکت; mTORC1; mammalian target of rapamycin complex 1; S6K1; 70-kDa ribosomal protein S6 kinase 1; TSC2; tuberous sclerosis protein 2; HFD; high-fat diet; PPAR-γ; peroxisome proliferator-activated receptor γ; SREBP-1; sterol regulatory element-binding protein

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Dual role of cyclic GMP in cardiac cell survival

Keywords: آکت; cGMP; PKG; mPTP; Akt; PP2A;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Genipin ameliorates age-related insulin resistance through inhibiting hepatic oxidative stress and mitochondrial dysfunction

Keywords: آکت; Akt; also called protein kinase B (PKB); ATP; adenosine tri-phosphate; BCA; bicinchoninic acid; H2DCFDA; 2,7-dichlorofluorescein diacetate; IR; insulin resistance; ivITT; intravenous insulin tolerance tests; JNK/SAPK; c-Jun kinases/stress-activated protei

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Gas6/Axl mediates tumor cell apoptosis, migration and invasion and predicts the clinical outcome of osteosarcoma patients

Keywords: آکت; Osteosarcoma; AXL; Apoptosis; Migration and invasion; AKT;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

FK506 induces endothelial dysfunction through attenuation of Akt and ERK1/2 independently of calcineurin inhibition and the caspase pathway

Keywords: آکت; ANOVA; analysis of variance; bFGF; basic fibroblast growth factor; CsA; cyclosporin A; DMSO; dimethylsulfoxide; EGF; epidermal growth factor; eNOS; endothelial nitrogen oxide synthase; ERK; extracellular-regulated kinase; FKBP; FK506-binding protein; GAPD

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Abamectin resistance in Drosophila is related to increased expression of P-glycoprotein via the dEGFR and dAkt pathways

Keywords: آکت; Avermectin; Resistance; Drosophila; EGFR; Akt;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Full-length Mst1 exhibits growth promoting function in human hepatocellular carcinoma cells

Keywords: آکت; HCC; hepatocellular carcinoma; Mst; mammalian sterile 20-like kinase; Stk; sterile 20-like kinase; PAK; p21 activated kinase; RASSF; RAS Association domain family; GAPDH; glyceraldehydes-3-phosphate dehydrogenase; PARP; poly ADP-ribose polymerase; FL; ful

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Production of Cyr61 protein is modulated by extracellular acidification and PI3K/Akt signaling in prostate carcinoma PC-3 cells

Keywords: آکت; NAC; N-acetylcysteine; ECM; extracellular matrix; PI3K; phosphoinositide 3-kinase; SDS; sodium dodecyl sulfate; HRP; horseradish peroxidase; ECL; enhanced chemiluminescence; siRNA; small interfering RNA; PBS; phosphate buffered saline; Akt; serine/threoni

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Molecular and cellular pharmacologyH89 (N-[2-p-bromocinnamylamino-ethyl]-5-isoquinolinesulphonamide) induces autophagy independently of protein kinase A inhibition

Keywords: آکت; Autophagy; Protein kinase A; H89; Akt;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Stimulation of α1-adrenoceptor or angiotensin type 1 receptor enhances DNA synthesis in human-induced pluripotent stem cells via Gq-coupled receptor-dependent signaling pathways

Keywords: آکت; α1-adrenoceptor; Angiotensin type 1 receptor; Mitogen-activated protein kinase; Akt; Gq-coupled receptor; Induced pluripotent stem cell;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Molecular and cellular pharmacologyCardioprotective effect of Danshensu against myocardial ischemia/reperfusion injury and inhibits apoptosis of H9c2 cardiomyocytes via Akt and ERK1/2 phosphorylation

Keywords: آکت; Danshensu; Myocardial ischemia/reperfusion; Apoptosis; Akt; ERK1/2;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

The inhibitory activity of atractylenolide Ш, a sesquiterpenoid, on IgE-mediated mast cell activation and passive cutaneous anaphylaxis (PCA)

Keywords: آکت; Ag; antigen; Akt; Protein kinase B; AT III; Atractylenolide III; ED50; the half maximal effective dose; FcεRI; Fc Epsilon Receptor 1 alpha; Gab2; Growth factor receptor bound protein 2-associated protein 2; IC50; the half maximal inhibitory concentration

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Spinal vascular endothelial growth factor (VEGF) and erythropoietin (EPO) induced phrenic motor facilitation after repetitive acute intermittent hypoxia

Keywords: آکت; AKT; protein kinase B; BDNF; brain derived neurotrophic factor; CIH; chronic intermittent hypoxia; EPO; erythropoietin; EPOR; erythropoietin receptor; ERK MAP kinase; extracellular regulated kinase mitogen activated protein kinase; HIF; hypoxia inducible

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Involvement of unfolded protein response, p53 and Akt in modulation of porcine reproductive and respiratory syndrome virus-mediated JNK activation

Keywords: آکت; PRRSV; JNK; Unfolded protein response (UPR); Akt; p53; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibition of constitutive Akt (PKB) phosphorylation by docosahexaenoic acid in the human breast cancer cell line MDA-MB-453

Keywords: آکت; PUFA; polyunsaturated fatty acid; RTK; receptor tyrosine kinase; FGFR; fibroblast growth factor receptor; IGFR; insulin-like growth factor receptor; PDK1; phosphoinositide-dependent kinase 1; mTOR; mammalian target of rapamycin; PDGF; platelet-derived gro

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

BIG1, a brefeldin A-inhibited guanine nucleotide-exchange protein regulates neurite development via PI3K-AKT and ERK signaling pathways

Keywords: آکت; AKT; protein kinase B; Arf; ADP-ribosylation factor; BFA; brefeldin A; BIG1; BFA-inhibited guanine nucleotide-exchange protein 1; DIV; days in vitro; ECL; Dulbecco's modification of Eagle's medium; ER; enhanced chemiluminescence; EDTA; ethylenediamine

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

mTOR complex 2 mediates Akt phosphorylation that requires PKCε in adult cardiac muscle cells

Keywords: آکت; Cardiomyocytes; PKCε; mTOR; Akt; Rapamycin; Torin1;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Piperine reverses high fat diet-induced hepatic steatosis and insulin resistance in mice

Keywords: آکت; HFD; high-fat diet; FFA; free fatty acid; ALT; alanine aminotransferase; AST; aspartate aminostransferase; AdipoR1; adiponectin receptor-1; AdipoR2; adiponectin receptor-2; AMPK; AMP-activated protein kinase; CPT1; carnitine palmitoyltransferase 1; CD36;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

ATP and UTP stimulate bone morphogenetic protein-2,-4 and -5 gene expression and mineralization by rat primary osteoblasts involving PI3K/AKT pathway

Keywords: آکت; ATP; adenosine-5′-triphosphate; ATPγS; adenosine-5′-O-(thiotriphosphate); ADP; adenosine-5′-diphosphate); ADPβS; adenosine-5′-O-(2-thiodiphosphate); BMPs; bone morphogenetic proteins; UTP; uridine-5′-triphosphate; ALP; alkaline phosphatase; PI

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Antitumor efficacy of piperine in the treatment of human HER2-overexpressing breast cancer cells

Keywords: آکت; AKT; protein kinase B; FAS; fatty acid synthase; HER2; human epidermal growth factor receptor 2; MAPKs; mitogen-activated protein kinases; MMP-2/-9; matrix metalloproteinase (MMP)-2/-9; EGF; epidermal growth factor; PARP; poly-ADPribose polymerase; SREBP-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Piperine, a dietary phytochemical, inhibits angiogenesis

Keywords: آکت; Angiogenesis; Piperine; Akt; Endothelial cell;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

miR-338-3p suppresses neuroblastoma proliferation, invasion and migration through targeting PREX2a

Keywords: آکت; miR-338-3p; PREX2a; PTEN; AKT; Neuroblastoma; Metastasis; Microarray;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Effect of endocannabinoids on IgE-mediated allergic response in RBL-2H3 cells

Keywords: آکت; 2-AG; 2-arachidonoyl glycerol; 5-LO; 5-lipoxygenase; Akt; protein kinase B; CB; cannabinoid; COX-2; cyclooxygenase-2; cPLA2; cytosolic phospholipase A2; ERK1/2; extracellular signal-regulated kinase 1/2; FAAH; fatty acid amide hydrolase; Gab2; GRB2-associ

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Taraxerol inhibits LPS-induced inflammatory responses through suppression of TAK1 and Akt activation

Keywords: آکت; Taraxerol; TAK1; MAPK; Akt; NF-κB; RAW264.7 cells;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Combined CpG and poly I:C stimulation of monocytes results in unique signaling activation not observed with the individual ligands

Keywords: آکت; TLRs; Toll-like receptors; CpG; unmethylated CpG oligodeoxynucleotides; poly I:C; polyinosinic-polycytidylic acid; NO; nitric oxide; iNOS; inducible nitric oxide synthase; CREB; cAMP response element-binding protein; NFκB; nuclear factor κB; PRRs; pat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Neuroprotective effect of Pycnogenol® following traumatic brain injury

Keywords: آکت; Akt; protein kinase B; CAT; catalase; CON; contralateral; JNK; c-Jun NH(2)-terminal kinase; ERK; extracellular signal-regulated protein kinase; G-6-PD; glucose-6-phosphate; GPx; glutathione peroxidase; GR; glutathione reductase; GSH; glutathione; GSK; gly

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Vasorelaxant action of an ethylacetate fraction of Euphorbia humifusa involves NO-cGMP pathway and potassium channels

Keywords: آکت; Euphorbia humifusa; Akt; eNOS; Nitric oxide; Guanosine 3′,5′-cyclic monophosphate; Potassium channels;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Research ArticleAll-trans retinoic acid potentiates the chemotherapeutic effect of cisplatin by inducing differentiation of tumor initiating cells in liver cancer

Keywords: آکت; ATRA; all-trans retinoic acid; cisplatin; cis-diammineplatinum (II); HCC; hepatocellular carcinoma; TIC; tumor initiating cell; DMSO; dimethyl surfoxide; EpCAM; epithelial cell adhesion molecule; FACS; fluorescence activated cell sorting; AKT; protein kin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Downregulation of pro-inflammatory mediators by a water extract of Schisandra chinensis (Turcz.) Baill fruit in lipopolysaccharide-stimulated RAW 264.7 macrophage cells

Keywords: آکت; Schisandra chinensis; Nitric oxide; Prostaglandin E2; Tumor necrosis factor-α; Nuclear factor-κB; Akt;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

The conserved role of the AKT/GSK3 axis in cell survival and glycogen metabolism in Rhipicephalus (Boophilus) microplus embryo tick cell line BME26

Keywords: آکت; 10-DEBC; 10-(4′-(N,N-Diethylamino) butyl)-2-chlorophenoxazine hydrochloride; AKT; Protein kinase B; CN; Negative control; DMSO; Dimethyl sulfoxide; dsRNA; Double-stranded RNA; dsCN; Unrelated dsRNA; dsAKT; Double-stranded RNA for protein kinase B; dsGSK

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

The Akt substrate Girdin is a regulator of insulin signaling in myoblast cells

Keywords: آکت; Girdin; C2C12; Insulin sensitivity; Akt; Abl;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

The role of SIRT1/AKT/ERK pathway in ultraviolet B induced damage on human retinal pigment epithelial cells

Keywords: آکت; RPE; retinal pigment epithelial; PI3K; phosphatidylinositol-3-kinase; AZA; 5-aza-2′-deoxycytidine; ROS; reactive oxygen species; MAP kinases; mitogen-activated protein (MAP) kinases; Ultraviolet B; SIRT1; AKT; Resveratrol; RPE;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Basic ScienceBerberine improves insulin resistance in cardiomyocytes via activation of 5′-adenosine monophosphate-activated protein kinase

Keywords: آکت; AMP; adenosine monophosphate; AMPK; 5′-adenosine monophosphate-activated protein kinase; BBR; berberine; DCM; diabetic cardiomyopathy; PBS; phosphate buffered solution; AKT; protein kinase B(PKB); GLUT-4; glucose transporter-4; IRS-1; insulin receptor s

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Akt2 expression is associated with good long-term prognosis in oestrogen receptor positive breast cancer

Keywords: آکت; Breast cancer; Akt; Protein kinase B; Oestrogen receptor; Long-term; Prognostic factor;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه