دانلود مقالات ISI درباره آکت + ترجمه فارسی

Hepatic transcriptional analysis in rats treated with Cassia occidentalis seed: Involvement of oxidative stress and impairment in xenobiotic metabolism as a putative mechanism of toxicity

Keywords: آکت; AIF; apoptosis inducing factor; AKT; v-akt murine thymoma viral oncogene homolog; BAX; Bcl-2 associated X gene; CAT; catalase; CO; Cassia occidentalis; CREB; cAMP responsive element binding protein; CYP; cytochrome p450; EROD; ethoxyresorufin-O-deethylase

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Cigarette smoke-induced alveolar epithelial-mesenchymal transition is mediated by Rac1 activation

Keywords: آکت; EMT; epithelial-mesenchymal transition; COPD; chronic obstructive pulmonary disease; CSE; cigarette smoke extract; TGF-β1; transforming growth factor β1; α-SMA; α-smooth muscle actin; MMP-9; matrix metalloproteinases-9; ATNA; anti-TGF-β1 neutralizi

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Fisetin inhibits human melanoma cell growth through direct binding to p70S6K and mTOR: Findings from 3-D melanoma skin equivalents and computational modeling

Keywords: آکت; Fisetin; AKT; mTOR; p70S6K; Melanoma

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

DHA2, a synthesized derivative of bisbibenzyl, exerts antitumor activity against ovarian cancer through inhibition of XIAP and Akt/mTOR pathway

Keywords: آکت; Ovarian cancer; Caspase-independent cell death; Autophagy; Akt; mTOR;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Early molecular and behavioral response to lipopolysaccharide in the WAG/Rij rat model of absence epilepsy and depressive-like behavior, involves interplay between AMPK, AKT/mTOR pathways and neuroinflammatory cytokine release

Keywords: آکت; Lipopolysaccharide (LPS); Neuroinflammation; Epileptogenesis; Absence epilepsy; WAG/Rij rats; mTOR; AKT; AMPK; Cytokines; NF-κB; Rapamycin;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Valproic acid enhances Oct4 promoter activity through PI3K/Akt/mTOR pathway activated nuclear receptors

Keywords: آکت; Muscle; Oct4; Nuclear receptor; iPSC; VPA; Akt;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

SG2NA recruits DJ-1 and Akt into the mitochondria and membrane to protect cells from oxidative damage

Keywords: آکت; Striatin; DJ-1; Akt; Mitochondria; Membrane; Oxidative stress; Parkinson׳s disease;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: Targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia

Keywords: آکت; ADAM; a disintegrin and metalloprotease; AICAR; 5-aminoimidazole-4-carboxamide ribonucleotide; AKT; protein kinase B (PKB); ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; AMPK; adenosine monophosphate (AMP) activated protein kinase; ANK;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Mediation of dopamine D2 receptors activation in post-conditioning-attenuated cardiomyocyte apoptosis

Keywords: آکت; Akt; protein kinase B; cAMP; adenylate cyclase; Bro; bromocriptine; Che; chelerythrine chloride; Cyt c; cytochrome c; DR2; dopamine D2 receotors; ERK1/2; extracellular signal-regulated kinase1/2; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GSK-3β; g

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Effects of activated fibroblasts on phenotype modulation, EGFR signalling and cell cycle regulation in OSCC cells

Keywords: آکت; Akt; protein kinase B; CAF; cancer associated fibroblast; EGFR; epidermal growth factor receptor; EMT; epithelial mesenchymal transition; ERK; extracellular signal-regulated protein kinase; FCM; fibroblast conditioned medium; HNSCC; head and neck squamous

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

DNA vaccination against membrane-bound Kit ligand: A new approach to inhibiting tumour growth and angiogenesis

Keywords: آکت; DNA vaccination; Tumour angiogenesis; Akt; mbKitL;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Opposite angiogenic outcome of curcumin against ischemia and Lewis lung cancer models: in silico, in vitro and in vivo studies

Keywords: آکت; 2-DE; two-dimensional gel electrophoresis; α1-AT; α1-antitrypsin; Akt; serine/threonine-protein kinase; BCIP; 3-bromo-4-chloro-5-indolyl phosphate; BSA; bovine serum albumin; CAM; chicken embryo chorioallantoic membrane; EC; endothelial cells; ECCM; epi

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Long-term administration of the TNF blocking drug Remicade (cV1q) to mdx mice reduces skeletal and cardiac muscle fibrosis, but negatively impacts cardiac function

Keywords: آکت; Muscular dystrophy; Inflammation; mdx mouse; Treatment; Myostatin; AKT; Signaling;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

The H+-ATP synthase: A gate to ROS-mediated cell death or cell survival

Keywords: آکت; AIF; apoptosis inducing factor; Akt; v-Akt murine thymoma viral oncogene; AP-1; activator protein 1; ARE; antioxidant responsive element; ASK1; apoptosis signal-regulated kinase 1; ATM; ataxia telangiectasia mutated; Duox; Dual oxidase enzymes; DUSP3; dua

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Down-regulation of lipid raft-associated onco-proteins via cholesterol-dependent lipid raft internalization in docosahexaenoic acid-induced apoptosis

Keywords: آکت; Docosahexaenoic acid (DHA); Lipid raft; Hsp90; EGFR; Akt; Cholesterol

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

TEIF associated centrosome activity is regulated by EGF/PI3K/Akt signaling

Keywords: آکت; Centrosome amplification; EGF; Akt; C-NAP1;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Mechanistic target of rapamycin (mTOR) signaling genes in decapod crustaceans: Cloning and tissue expression of mTOR, Akt, Rheb, and p70 S6 kinase in the green crab, Carcinus maenas, and blackback land crab, Gecarcinus lateralis

Keywords: آکت; Target of rapamycin; Rheb; Akt; p70 S6 kinase; Molting; Crustacea; Y-organ; Ecdysteroid

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Novel anti-inflammatory function of NSC95397 by the suppression of multiple kinases

Keywords: آکت; NSC95397; Anti-inflammatory effects; Inflammatory mediators; Multiple kinases; AKT; IKKα/β; PG; prostaglandin; NO; nitric oxide; COX; cyclooxygenase; iNOS; inducible NO synthase; TNF-α; tumor necrosis factor α; ERK; extracellular signal-related kinase

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Pseudoginsenoside-F11 (PF11) exerts anti-neuroinflammatory effects on LPS-activated microglial cells by inhibiting TLR4-mediated TAK1/IKK/NF-κB, MAPKs and Akt signaling pathways

Keywords: آکت; PF11; Microglia; TLR4; NF-κB; MAPKs; Akt; PF11; pseudoginsenoside-F11; COX-2; cyclooxygenase-2; iNOS; inducible nitric oxide synthase; IL; interleukin; PGE2; prostaglandin E2; LPS; lipopolysaccharide; MAPKs; mitogen-activated protein kinases; TLR4; toll-

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

ReviewSalvia miltiorrhiza: An ancient Chinese herbal medicine as a source for anti-osteoporotic drugs

Keywords: آکت; ALP; alkaline phosphatase; AKT; also known as protein kinase B; BGP; bone-Gla protein; BMC; bone mineral content; BMD; bone mineral density; c-Fos; cellular proto-oncogene; COX-2/PGE2; cyclooxygenase-2/prostaglandin E2; DEXA; dual-energy x-ray absorptiome

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

Matrigel: From discovery and ECM mimicry to assays and models for cancer research

Keywords: آکت; BME; basement membrane extract; EGF; epidermal growth factor; TGF beta; transforming growth factor beta; IGF; insulin-like growth factor; PDGF; platelet-derived growth factor; VEGF; vascular endothelial cell growth factor; NIH; National Institutes of Heal

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

Insulin, IGF-1 and GLP-1 signaling in neurodegenerative disorders: Targets for disease modification?

Keywords: آکت; Aβ; amyloid beta; AD; Alzheimer's disease; Akt; protein kinase B; α-syn; α-synuclein; BAD; Bcl-2 antagonist of death; BBB; blood brain barrier; Bcl-2; B-cell lymphoma 2; Bcl-XL; B-cell lymphoma extra large; Bim; Bcl-2 interacting mediator of death; cAM

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2014 سفارش ترجمه

Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy

Keywords: آکت; Akt; protein kinase B; CPT-11; irinotecan; CMT4D; Charcot-Marie-Tooth disease, type 4D; DFO; deferoxamine (or desferrioxamine B); DpC; di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone; DpT; di-2-pyridylketone thiosemicarbazone; Dp44mT; di-

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2014 سفارش ترجمه

Ribonucleoprotein HNRNPA2B1 Interacts With and Regulates Oncogenic KRAS in Pancreatic Ductal Adenocarcinoma Cells

Keywords: آکت; Signal Transduction; Carcinogenesis; Oncogene; Mouse Model; AKT; c-akt murine thymoma oncogene homolog 1; FCS; fetal calf serum; GFP; green fluorescent protein; GTP; guanosine triphosphate; HA; hemagglutinin; hnRNP; heterogeneous nuclear ribonucleoprotein

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2014 سفارش ترجمه

S100A4 negatively regulates β-catenin by inducing the Egr-1-PTEN-Akt-GSK3β degradation pathway

Keywords: آکت; EMT; epithelial-to-mesenchymal transition; GSK; glycogen synthase kinase; MMP; matrix metalloproteinase; PTEN; phosphatase and tensin homolog; S100A4; β-Catenin; Egr-1; Akt; Breast cancer;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2014 سفارش ترجمه

AKT inhibition synergistically enhances growth-inhibitory effects of gefitinib and increases apoptosis in non-small cell lung cancer cell lines

Keywords: آکت; NSCLC; EGFR; AKT; S6; Gefitinib; Akt inhibitor; Synergism;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2014 سفارش ترجمه

HDL and cognition in neurodegenerative disorders

Keywords: آکت; ABC; ATP-binding cassette transporter; AD; Alzheimer's disease; Akt; protein kinase B; ALS; amyotrophic lateral sclerosis; apo; apolipoprotein; Aβ; amyloid-β protein; BBB; blood-brain barrier; CAA; cerebral amyloid angiopathy; CE; cholesterol ester; C

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2014 سفارش ترجمه

Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway

Keywords: آکت; PI3K pathway; Targeted therapy; Predictive biomarkers; 4EBP1; 4E-binding protein 1; AKT; protein kinase-B; AMPK; AMP-activated protein kinase; COSMIC; Catalogue of Somatic Mutations in Cancer; eIF4E; eukaryotic initiation factor 4E; ERK; extracellular-sig

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2014 سفارش ترجمه

Eicosapentaenoic acid induces neovasculogenesis in human endothelial progenitor cells by modulating c-kit protein and PI3-K/Akt/eNOS signaling pathways

Keywords: آکت; Eicosapentaenoic acid; Neovasculogenesis; c-kit; Akt; eNOS; microRNA 221; Human endothelial progenitor cells;

دانلود رایگان متن کامل مقاله ISI 62 صفحه سال انتشار : 2014 سفارش ترجمه

LGR5 is a biomarker for stratification of HER-2 positive breast cancer patients and personalized treatment

Keywords: آکت; AKT; v-akt murine thymoma viral oncogene; CTNNB1; catenin (cadherin-associated protein), beta 1; HER-2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2; IgG1; immunoglobulin G 1; LGR5; leucine-rich repeat containing G protein-coupled receptor 5;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

miRNA-7-5p inhibits melanoma cell migration and invasion

Keywords: آکت; miRNA; microRNA; IRS-2; insulin receptor substrate-2; IRS-1; insulin receptor substrate-1; PI3K; phosphatidylinositol 3-kinase; Akt; protein kinase B; RT-qPCR; reverse transcription and quantitative polymerase chain reaction; BRAF; v-Raf murine sarcoma vi

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Syndecan 4 regulation of PDK1-dependent Akt activation

Keywords: آکت; S4; syndecan 4; PI3K; phosphatidylinositol 3 kinase; myrPKCα; myristoylated protein kinase C; PAK; p21 protein (CDC42/Rac)-activated kinase; Syndecan; PKC; AKT; Angiogenesis;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Akt1 as a putative regulator of Hox genes

Keywords: آکت; Hox; homeobox gene; Akt; v-akt murine thymoma viral oncogene homolog; PKB; protein kinase B; PI3K; phosphatidylinositol 3-kinase; RT-PCR; reverse transcription-polymerase chain reaction; MEF; mouse embryonic fibroblast; GEO; gene expression omnibus; COBRA

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Development of Akt-activated GSK3β inhibitory peptide

Keywords: آکت; GSK3β; Akt; Diabete mellitus; Drug discovery;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Picropodophyllin inhibits tumor growth of human nasopharyngeal carcinoma in a mouse model

Keywords: آکت; Nasopharyngeal carcinoma; Insulin-like growth factor-1 receptor; Picropodophyllin; Akt; Nude mouse;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Reactivation of AKT signaling following treatment of cancer cells with PI3K inhibitors attenuates their antitumor effects

Keywords: آکت; PI3K; phosphatidylinositol-3-kinase; PTEN; phosphatase and tensin homolog; PI3K inhibitors; AKT; Cancer; Resistance; Signaling;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Targeted deletion of Kif18a protects from colitis-associated colorectal (CAC) tumors in mice through impairing Akt phosphorylation

Keywords: آکت; Kinesin-8 Kif18a; Tumorigenesis; Colitis-associated cancer; Knock-out mice; AOM-DSS model; Akt;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Chloroquine stimulates glucose uptake and glycogen synthase in muscle cells through activation of Akt

Keywords: آکت; Chloroquine; ATM; Akt; Glucose uptake; Glycogen synthase kinase-3β; Glycogen synthase;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Determinants of the tumor suppressor INPP4B protein and lipid phosphatase activities

Keywords: آکت; PI3K; by phosphatidyl 3-kinase; PI4K; phosphatidyl 4-kinase; PI5K; phosphatidyl 5-kinase; INPP4B; inositol polyphosphate 4-phosphatase type II; PTP; protein tyrosine phosphatase; pNPP; para-nitrophenyl phosphate; DifMUP; 6,8-difluoro-4-methylumbelliferyl

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Perifosine, an AKT inhibitor, modulates ovarian cancer cell line sensitivity to cisplatin-induced growth arrest

Keywords: آکت; Perifosine; Cisplatin; AKT; Ovarian CANCER; Gene expression;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Vasopressin activates Akt/mTOR pathway in smooth muscle cells cultured in high glucose concentration

Keywords: آکت; AVP; arginine vasopressin; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; PI3K; phosphatidyl inositol-3 kinase; AMPK; AMP-activated protein kinase; PKC; protein kinase C, Akt or protein kinase B; TSC1/TSC2; tubero sclerosis protein 1 and 2;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

β-Ionone attenuates LPS-induced pro-inflammatory mediators such as NO, PGE2 and TNF-α in BV2 microglial cells via suppression of the NF-κB and MAPK pathway

Keywords: آکت; β-Ionone; Nitric oxide; Prostaglandin E2; Tumor necrosis factor-α; Nuclear factor-κB; Akt;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

JNK pathway may be involved in isoflurane-induced apoptosis in the hippocampi of neonatal rats

Keywords: آکت; Akt; protein kinase B; AP-1; activator-protein 1; Bcl-2; B cell lymphoma/lewkmia-2; CNS; central nervouse system; DG; dentate gyrus; GSK-3β; glycogen synthase kinase 3β; i.c.v; intracerebroventricular; JNK; c-jun N-terminal kinase; PI3K; phosphatidylino

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Combination therapy using Notch and Akt inhibitors is effective for suppressing invasion but not proliferation in glioma cells

Keywords: آکت; Glioma; Molecular targeted therapy; Notch; Akt; Proliferation; Invasion;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Antimicrobial peptide LL-37 attenuates LTA induced inflammatory effect in macrophages

Keywords: آکت; Staphylococcus aureus; LTA; Antimicrobial peptide; LL-37; p38MAPK; Akt;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Salinomycin inhibits Akt/NF-κB and induces apoptosis in cisplatin resistant ovarian cancer cells

Keywords: آکت; Salinomycin; Akt; Cisplatin resistance; Ovarian cancer; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Pregnane alkaloids from Sarcococca hookeriana var. digyna

Keywords: آکت; cAMP; cyclic adenosine monophosphate; PKA; protein kinase A; CREB; cAMP response element binding protein; PI3K; phosphatidylinositol-3 kinase; Akt; protein kinase B; mTOR; mammalian target of rapamycin; MAPK; mitogen-activated protein kinase; ERK; extrace

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Bimatoprost protects retinal neuronal damage via Akt pathway

Keywords: آکت; Bimatoprost; Retinal ganglion cell; Retinal damage; Akt; ERK (Extracellular signal-regulated kinase);

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Phosphorylation accelerates geldanamycin-induced Akt degradation

Keywords: آکت; Hsp90 inhibitor; Akt; CHIP; Phosphorylation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Role of glycogen synthase kinase-3β in ketamine-induced developmental neuroapoptosis in rats

Keywords: آکت; AKT; apoptosis; glycogen synthase kinase-3β; ketamine; lithium; protein kinase B;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه