دانلود مقالات ISI درباره Aml + ترجمه فارسی

The poly(ADP-ribose) polymerase inhibitor olaparib induces up-regulation of death receptors in primary acute myeloid leukemia blasts by NF-κB activation

Keywords: PARP1; Lynparza; AML; FAS; TRAIL receptors; BRCA1; DNA repair associated; BRCA2; DNA repair associated; DR4; TNF receptor superfamily member 10a (TNFRSF10A); DR5; TNF receptor superfamily member 10b (TNFRSF10B); DSBs; DNA double strand breaks; FAS; Fas ce

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Deubiquitylating enzymes as cancer stem cell therapeutics

Keywords: Protein-IPSC; protein-induced pluripotent stem cells; CSCs; cancer stem cells; DUBs; deubiquitylating enzymes; ESCs; embryonic stem cells; PTMs; post-translational modifications; AML; acute myelogenous leukemia; USP/UBP; ubiquitin-specific processing prot

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Therapeutic implication of vascular endothelial growth factor receptor-1 (VEGFR-1) targeting in cancer cells and tumor microenvironment by competitive and non-competitive inhibitors

Keywords: ADCC; antibody dependent cell-mediated cytotoxic activity; ALL; acute lymphoid leukemia; AML; acute myeloid leukemia; CXCL; C-X-C motif chemokine ligand; ECM; extra-cellular matrix; EGFR; epidermal growth factor receptor; ERK; extracellular signal-regulat

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

Redox control of cancer cell destruction

Keywords: ABC transporters; ATP-binding cassette transporters; ADCC; antibody-dependent cell-mediated cytotoxicity; ADCP; antibody-dependent cancer cell phagocytosis; AML; acute myeloid leukemia; APE1; apurinic/apyrimidinic endonuclease 1; ASK-1; apoptosis signal-r

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

The traditional uses, phytochemistry, and pharmacology of Atractylodes macrocephala Koidz.: A review

Keywords: AM; Atractylodes macrocephala Koidz.; TCM; traditional Chinese medicine; UPLC; ultra-performance liquid chromatography; PDA; photo-diode array; IR; infrared spectroscopy; HS-LP-LPE; headspace liquid phase-liquid-phase extraction; GC-MS; gas chromatography

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2018 سفارش ترجمه

Dueling for dual inhibition: Means to enhance effectiveness of PI3K/Akt/mTOR inhibitors in AML

Keywords: AML; mTOR; PI3K; Akt; Resistance mechanisms; Dual inhibitors; Rapalogs;

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2018 سفارش ترجمه

Antibody-drug conjugates (ADCs): Potent biopharmaceuticals to target solid and hematological cancers- an overview

Keywords: Antibody-drug conjugates; Monoclonal antibodies; Anticancer; Drug resistance; Solid tumors; Hematological tumors; ADC; Antibody-Drug Conjugate; ALCL; Anaplastic Large Cell Lymphoma; ALL; Acute Lymphoblastic Leukemia; AML; Acute Myeloid Leukemia; BCMA; B C

دانلود رایگان متن کامل مقاله ISI 62 صفحه سال انتشار : 2018 سفارش ترجمه

Reformation in chimeric antigen receptor based cancer immunotherapy: Redirecting natural killer cell

Keywords: NK cell; natural killer cell; IFN-γ; interferon-γ; IL; interleukin; TNF-α; tumor necrosis factor-α; CCL; C-C motif ligand; GM-CSF; granulocyte-macrophage colony-stimulating factor; ADCC; antibody dependent cell-mediated cytotoxicity; TRAIL; TNF-relate

دانلود رایگان متن کامل مقاله ISI 69 صفحه سال انتشار : 2018 سفارش ترجمه

Nucleosidic DNA demethylating epigenetic drugs - A comprehensive review from discovery to clinic

Keywords: ALL; Acute lymphoblastic leukemia; AML; Acute myeloid leukemia; AUC; Area under the curve; AZA; 5-azacytidine; 5-aza-CdR; 2′-deoxy-5-azacytidine; 5-aza-CR; 5-azacytidine; AZN; Azanucleosides; BED; Biologically effective dose; BSC; Best supportive care;

دانلود رایگان متن کامل مقاله ISI 78 صفحه سال انتشار : 2018 سفارش ترجمه

Autophagy as a pharmacological target in hematopoiesis and hematological disorders

Keywords: 3-MA; 3-methyladenine; ALL; acute lymphoblastic leukemia; AMKL; acute megakaryoblastic leukemia; AML; acute myeloid leukemia; AMPK; 5′-adenosine monophosphate-activated protein kinase; APL; acute promyelocytic leukemia; Atg; autophagy-related proteins;

دانلود رایگان متن کامل مقاله ISI 80 صفحه سال انتشار : 2018 سفارش ترجمه

Nanomedicines for the treatment of hematological malignancies

Keywords: BMSC; Bone marrow stromal cell; BM; bone marrow; VCAM1; Vascular cell adhesion molecule 1; VLA-4; Very late antigen-4; HM; hematological malignancy; CLL; Chronic lymphocytic leukemia; ICAM1; Intercellular adhesion molecule 1; VEGF; Vascular endothelial gr

دانلود رایگان متن کامل مقاله ISI 85 صفحه سال انتشار : 2018 سفارش ترجمه

A Phase I/II Trial of the Combination of Azacitidine and Gemtuzumab Ozogamicin for Treatment of Relapsed Acute Myeloid Leukemia

Keywords: AML; Antibody-drug conjugate; Hypomethylating agents; Phase I clinical trials; Phase II clinical trials;

دانلود رایگان متن کامل مقاله ISI 88 صفحه سال انتشار : 2018 سفارش ترجمه

Acute Myeloid Leukemia After Radium-223 Therapy: Case Report

Keywords: AML; Microenvironment; Prostate Cancer; Radium-223; Secondary leukemia;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

The potential association of the transcription levels of the ABO gene with the disease phases in AML patients

Keywords: ABO blood typing; ABO gene sequencing; AML; transcription levels;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Safety of CT-Guided Bone Marrow Biopsy in Thrombocytopenic Patients: A Retrospective Review

Keywords: AML; acute myeloid leukemia; CI; confidence interval; CML; chronic myeloid leukemia; MDS; myelodysplastic syndrome;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Do cytogenetics affect the post-remission strategy for older patients with AML in CR1?

Keywords: Acute myeloid leukemia; Age; AML; Azacitidine; Clofarabine; Consolidation; CPX-351; Cytarabine; Cytogenetics; Daunorubicin; Decitabine; Minimal residual disease; MRD; Reduced intensity conditioning; RIC; Risk; TP53; Transplant;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

High prognostic value of pre-allogeneic stem cell transplantation minimal residual disease detection by WT1 gene expression in AML transplanted in cytologic complete remission

Keywords: Allogeneic hematopoietic stem cell transplant; AML; Minimal residual disease (MRD); WT1 gene expression;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of N-substituted 7-azaindoles as Pan-PIM kinase inhibitors - Lead series identification - Part II

Keywords: Pan-PIM kinases; X-ray crystallography; AML; PK/PD; Hit-to-Lead; Small molecule inhibitor; Cancer;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

MicroRNA-181a and its target Smad 7 as potential biomarkers for tracking child acute lymphoblastic leukemia

Keywords: ALL; Acute lymphoblastic leukemia; AML; acute myeloid leukemia; CDKs; cyclin-dependent kinases; CLL; chronic lymphocytic leukemia; ELISA; enzyme linked immunosorbent assay; GSK3β; glycogen synthase kinase 3β; I-Smads; inhibitory Smads; qRT-PCR; quantita

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Consolidation with autologous stem cell transplantation in first remission is safe and effective in AML patients above 65 years

Keywords: Autologous; Transplant; Elderly; AML; Survival;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

BRAF signals to pro-apoptotic BIM to enhance AraC cytotoxicity induced in AML cells by Vitamin D-based differentiation agents

Keywords: Vitamin D; BRAF; BIM; Apoptosis; Cytarabine; AML;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Role of MRP-1 and GST-Pi in MDR and their inhibition by indomethacin in AML

Keywords: MDR; multidrug resistance; MRP-1; multidrug resistance-associated protein-1; GST-Pi; Glutathione-S-Transferase-Pi; NSAIDs; non-steroidal anti-inflammatory drugs; AML; acute myeloid leukemia; CR; complete remission; UR; un-remitted; DFS; disease-free survi

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

DICER1 gene and miRNA dysregulation in mesenchymal stem cells of patients with myelodysplastic syndrome and acute myeloblastic leukemia

Keywords: MDS; AML; Bone marrow microenvironment; MSC; Niche; miRNA;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Hematologic neoplasms: Dendritic cells vaccines in motion

Keywords: DCs; dendritic cells; TAA; tumor-associated antigens; APC; antigen presenting cells; mDCs; myeloid dendritic cells; pDCs; plasmacytoid dendritic cells; HLA; human leukocyte antigen; Ag Antigens; abs antibodies; PBMCs; peripheral blood mononuclear cells; G

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Low serum vitamin D levels are associated with shorter survival after first-line azacitidine treatment in patients with myelodysplastic syndrome and secondary oligoblastic acute myeloid leukemia

Keywords: MDS; AML; Azacitidine; Vitamin D; Survival;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

DDX41-related myeloid neoplasia

Keywords: DDX41; AML; Familial leukemia; MDS; Mutations;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Dual Inhibition of Mnk2 and FLT3 for potential treatment of acute myeloid leukaemia

Keywords: Mnk inhibitor; FLT3 inhibitor; Dual inhibitor; AML; Drug discovery; Anti-leukaemic agent; AML; acute myeloid leukaemia; CDK; cyclin-dependent kinase; eIF; eukaryotic initiation factor; Erk; extracellular signal-regulated kinase; FLT3; Fms-like tyrosine ki

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Modification of cytokine-induced killer cells with folate receptor alpha (FRα)-specific chimeric antigen receptors enhances their antitumor immunity toward FRα-positive ovarian cancers

Keywords: ACT; adoptive cellular immunotherapy; AICD; activation induced cell death; ALL; acute lymphocytic leukemia; AML; acute myeloid leukemia; BsAb; bispecific antibody; CA125; cancer antigen-125; CARs; chimeric antigen receptors; CBMCs; cord blood mononuclear

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Mechanisms of Resistance to FLT3 Inhibitors and the Role of the Bone Marrow Microenvironment

Keywords: FLT3 inhibitors; FLT3-ITD; AML; Stem cell niche;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Intentional Percutaneous Laceration of the Anterior Mitral Leaflet to Prevent Outflow Obstruction During Transcatheter Mitral Valve Replacement

Keywords: left ventricular outflow tract obstruction; mitral valve; structural heart disease; transcatheter mitral valve replacement; valvular heart disease; AML; anterior mitral valve leaflet; CT; computed tomography; LA; left atrium; LAMPOON; laceration of the an

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

How can one optimize induction therapy in AML?

Keywords: Acute myeloid leukemia; AML; Ara-C; Azacitidine; Induction; Cladribine; Clofarabine; CPX-351; Cytarabine; Daunorubicin; Etoposide; Fludarabine; Gemtuzumab ozogamicin; Idarubicin; Vadastuximab talirine;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Structure-based design, synthesis and in vitro antiproliferative effects studies of novel dual BRD4/HDAC inhibitors

Keywords: BET; HDAC; Dual inhibitors; Myc; AML;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Studies of CDK 8/19 inhibitors: Discovery of novel and selective CDK8/19 dual inhibitors and elimination of their CYP3A4 time-dependent inhibition potential

Keywords: ADME; absorption, distribution, metabolism, and excretion; AML; acute myelogenous leukemia; AUC; area under the blood concentration time curve; b.i.d.; twice a day; CDK; Cyclin-dependent kinase; CLtotal; clearance; Cmax; maximum drug concentration; CRC; c

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

AML in 2017: Advances in clinical practice

Keywords: Acute myeloid leukemia; AML; Hedgehog; Histone deacetylase; IDH; Minimal residual disease; MRD; Transplant;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

The Development of FLT3 Inhibitors in Acute Myeloid Leukemia

Keywords: FLT3-ITD; FLT3-TKD; AML; FLT3 inhibitors; FLT3 mutation;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

ALDHs in normal and malignant hematopoietic cells: Potential new avenues for treatment of AML and other blood cancers

Keywords: ALDH; AML; Aldehyde dehydrogenase; Leukemic stem cells; ROS; 4-HNE;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

Daunorubicin 90 mg/m2 in Acute Myeloid Leukemia Induction: Increased Toxicity in Young Patients

Keywords: AML; Anthracycline; High-dose; Remission; Survival;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

Overcoming ABC transporter-mediated multidrug resistance: The dual role of tyrosine kinase inhibitors as multitargeting agents

Keywords: MDR; BCR-ABL inhibitors; EGFR inhibitors; VEGFR inhibitors; Drug combinations; ABC; ATP binding cassette; ADME-tox; absorption, distribution, metabolism, excretion, toxicity; AKT; v-akt murine thymoma viral oncogene homolog; ALL; acute lymphoblastic leuke

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Radotinib induces high cytotoxicity in c-KIT positive acute myeloid leukemia cells

Keywords: AML; acute myeloid leukemia; TKI; tyrosine kinase inhibitor; BMCs; bone marrow cells; Radotinib (PubChem CID: 16063245); Radotinib; Acute myeloid leukemia; c-KIT; CD117; Cytotoxicity; Anti-leukemic activity;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

FLAG-Ida Regimen as Bridge Therapy to Allotransplantation in Refractory/Relapsed Acute Myeloid Leukemia Patients

Keywords: AML; Bridge to allotransplantation; Prognosis; Therapy;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Sepsis and Acute Myeloid Leukemia: A Population-Level Study of Comparative Outcomes of Patients Discharged From Texas Hospitals

Keywords: AML; Cancer; Mortality; Outcomes; Sepsis;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

Sub-clonal analysis of the murine C1498 acute myeloid leukaemia cell line reveals genomic and immunogenic diversity

Keywords: AML; acute myeloid leukaemia; CGH; comparative genomic hybridization arrays; CTL; cytotoxic T lymphocyte; qPCR; real time quantitative PCR; CR; complete remission; GvL; graft-versus-leukaemia; HSCT; haematopoietic stem cell transplantation; LICs; leukaemi

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

Harnessing the CD1 restricted T cell response for leukemia adoptive immunotherapy

Keywords: MHC; major histocompatibility complex; ACT; adoptive cell therapy; DC; Dendritic cells; AML; T-ALL. B-ALL; mLPA; methyl-lysophosphatidic acid; HSCT; hematopoietic stem cell transplantation; GVL; graft versus leukemia; GVHD; graft versus host disease; iNKT

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Efficacy of recombinant factor VIIa for severe bleeding complicated by platelet transfusion refractoriness in patients with hematologic malignancies

Keywords: rFVIIa; recombinant factor VIIa; PTR; platelet transfusion refractoriness; CR; complete responses; PR; partial response; NR; no response; CCI; corrected count increment; PI; platelet count increment; BSA; body surface area; PD; the dose of platelets trans

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

CAR-T therapy for leukemia: progress and challenges

Keywords: CAR; chimeric antigen receptor; AML; acute myeloid leukemia; CML; chronic myeloid leukemia; ALL; acute lymphoblastic leukemia; CLL; chronic lymphoblastic leukemia; HSCT; allogeneic hematopoietic stem cell transplantation; scFv; single-chain variable fragm

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Diagnostic Accuracy of Multiparametric Magnetic Resonance Imaging to Identify Clear Cell Renal Cell Carcinoma in cT1a Renal Masses

Keywords: kidney neoplasms; carcinoma; renal cell; magnetic resonance imaging; neoplasm metastasis; histology; AML; angiomyolipoma; ccLS; clear cell likelihood score; ccRCC; clear cell RCC; mpMRI; multiparametric MRI; MRI; magnetic resonance imaging; NPV; negative

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Chimeric antigen receptor-engineered natural killer and natural killer T cells for cancer immunotherapy

Keywords: aAPC; artificial antigen-presenting cells; αGalCer; α-galactosylceramide; ACT; adoptive cell transfer; ADCC; antibody-dependent cell-mediated cytotoxicity; ALL; Acute Lymphoblastic Leukemia; AML; acute lymphoid leukemia; CAR; chimeric antigen receptor;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

The role of miRNA-223 in cancer: Function, diagnosis and therapy

Keywords: miRNAs; MicroRNAs; UTR; The 3′ untranslated region; oncomiRs; Oncogenic miRNAs; miR-223; miRNA-223; T-ALL; T-cell acute lymphoblastic leukemia; AML; Acute myeloid leukemia; NSCLC; Nonsmall cell lung cancer; C/EBP; CCAAT-enhancer-binding protein; NFI-A;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

IRF2-INPP4B axis participates in the development of acute myeloid leukemia by regulating cell growth and survival

Keywords: AML; acute myeloid leukemia; IRF2; interferon-regulatory factor 2; INPP4B; inositol polyphosphate-4-phosphatase, type-II; STAT; signal transducer and activator of transcription; Acute myeloid leukemia; IRF2; INPP4B; Growth; Survival;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Multiway analysis methods applied to the fluorescence excitation-emission dataset for the simultaneous quantification of valsartan and amlodipine in tablets

Keywords: 3W-PLS; three-way partial least squares; ALS; alternating least squares; AML; amlodipine besylate; ANOVA; one-way analysis of variance; DAD; diode array detector; EEM; excitation-emission matrix; GRAM; generalized rank annihilation method; HCl; hydrochlor

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه