Talampanel
Keywords: AMPA; epilepsy; glutamate; neuroprotection; talampanel;
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Characterization of the anticonvulsant profile of isonicotinic acid benzylamide in various experimental seizure models in mice
Keywords: Isonicotinic acid benzylamide; Maximal electroshock; Chimney test; Protective index; Bicuculline; Pentylenetetrazole; AMPA; Kainic acid; NMDA; Pilocarpine
The colocalization of CGRP receptor and AMPA receptor in the spinal dorsal horn neuron of rat: A morphological and electrophysiological study
Keywords: Calcitonin gene-related peptide (CGRP); AMPA; Micro-iontophoresis; Extracellular recording; Double immunofluorescence labeling; Wide dynamic range (WDR) neurons;
5-Lipoxygenase inhibitor MK-886 increases GluR1 phosphorylation in neuronal cultures in vitro and in the mouse cortex in vivo
Keywords: Glutamate; AMPA; 5-Lipoxygenase (5-LOX, 5-LO); 5-Lipoxygenase activating protein (FLAP)
Activation of silent synapses with sustained but not decremental long-term potentiation
Keywords: Hippocampus; Synaptic plasticity; NMDA; AMPA; CA1
AMPA receptor activation reduces epileptiform activity in the rat neocortex
Keywords: AMPA; NMDA; GABA; Clomethiazole; Epilepsy; Neocortex
Tricyclic antidepressants, but not the selective serotonin reuptake inhibitor fluoxetine, bind to the S1S2 domain of AMPA receptors
Keywords: Tricyclic antidepressants; Ionotropic glutamate receptors; AMPA; Fluoxetine; S1S2; Selective serotonin reuptake inhibitor
Involvement of calpain in AMPA-induced toxicity to rat cerebellar Purkinje neurons
Keywords: AMPA; α-Spectrin; Calpain; Cerebellum; Neuronal death
Auditory nerve input is not an absolute requirement for the expression, distribution and calcium permeability of AMPA receptors in the adult rat ventral cochlear nucleus
Keywords: Deafferentation; Glutamate receptor; AMPA; Auditory system; Cochlear nuclei
The new 2,3-benzodiazepine derivative EGIS-8332 inhibits AMPA/kainate ion channels and cell death
Keywords: Primary neuronal culture; Purkinje neuron; GluR1; Neuroprotection; AMPA; Kainate; NMDA; Stereoselectivity; Benzodiazepine;
Effect of novel AMPA antagonist, NS1209, on status epilepticus: An experimental study in rat
Keywords: AMPA; Diazepam; Neuroprotection; Spatial memory; Status epilepticus
Influence of complexation phenomena with multivalent cations on the analysis of glyphosate and aminomethyl phosphonic acid in water
Keywords: Glyphosate; AMPA; FMOC derivatization; Metal interferences; Complexation; VMINTEQ modelling
Presynaptic mechanisms involved in the expression of STP and LTP at CA1 synapses in the hippocampus
Keywords: Long-term potentiation; Hippocampal; Pr; Glutamate release; NMDA; AMPA; Kainate; GluR5
Effects of gamma hydroxybutyric acid on inhibition and excitation in rat neocortex
Keywords: GHB; baclofen; NMDA; AMPA; presynaptic; aCSF; artifical cerebrospinal fluid; APV; d-(â)2-amino-5-phosphonovaleric acid; DNQX; 6,7-dinitroquinoxaline-2,3-dione; EPSC; excitatory postsynaptic current; GHB; gamma hydroxybutyric acid; IPSC; inhibitory posts
The role of spontaneous activity in development of the endbulb of Held synapse
Keywords: AMPA; alpha amino-3-hydroxy-5-methyl-4-isoxazole propionate; eEPSC; evoked excitatory postsynaptic currents; mEPSC; miniature excitatory postsynaptic currents; AVCN; anteroventral cochlear nucleus; aCSF; artificial cerebral spinal fluid; TTX; tetrodotoxin
mGluR5 is involved in dendrite differentiation and excitatory synaptic transmission in NTERA2 human embryonic carcinoma cell-derived neurons
Keywords: Stem cell; NTERA2-derived neuron; Metabotropic glutamate receptor; AMPA; NMDA; Electrophysiology
Monitoring synaptic transmission in primary neuronal cultures using local extracellular stimulation
Keywords: Synaptic transmission; Neuronal culture; GABA; AMPA; Extracellular stimulation
Calcium mediated excitotoxicity in neurofilament aggregate-bearing neurons in vitro is NMDA receptor dependant
Keywords: ALS; AMPA; NMDA; Calcium-imaging; Excitotoxicity; Neurofilament
Novel anticonvulsant drugs
Keywords: AED; antiepileptic drug; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid; CBZ; carbamazepine; DMCM; methyl-6,7-dimethoxy-4-ethyl-β-carboline-3-carboxylate; fPHT; free PHT (not bound to protein); GABA; γ-aminobutyric acid; GBP; gabapentin; G
Stress during development: Impact on neuroplasticity and relevance to psychopathology
Keywords: ABN-LG; arched-back nursing and licking/grooming; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid; BDNF; brain derived neurotrophic factor; FGF-2; basic fibroblast growth factor; HPA; hypothalamus-pituitary-adrenal; LTP; long-term potentiatio
N-Methyl-d-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease
Keywords: 3-NP; 3-nitropropionic acid; ADP; adenosine 5â²-diphosphate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid; AMPAR; AMPA receptor; AP-2; adaptor protein-2; ATP; adenosine 5â²-triphosphate; cAMP; cyclic adenosine 5â²-monophosphate; CNS; ce
Differential localization of the GluR1 and GluR2 subunits of the AMPA-type glutamate receptor among striatal neuron types in rats
Keywords: AMPA; α-amino-3-hydroxy-5-methyl-ioxazole-4-propionic acid; CALB; calbindin; CALR; calretinin; ChAT; choline acetyltransferase; CLSM; confocal laser scanning microscope; EM; electron microscope; ENK; enkephalin; GPe; external segment, globus pallidus; GP
Synaptic transmission changes in the pyramidal cells of the hippocampus in streptozotocin-induced diabetes mellitus in rats
Keywords: Hippocampus; Diabetes mellitus; Synaptic transmission; Long-term potentiation; NMDA; AMPA
Theta bursts set up glutamatergic as well as GABA-ergic plasticity in neonatal rat hippocampal CA1 neurons
Keywords: Neurotransmitters, modulators, transporters, and receptors, GABAGABA; Reversal potential; Plasticity; Hippocampal CA1 neuron; Inhibitory postsynaptic current; Theta burst; AMPA
Extended therapeutic time window after focal cerebral ischemia by non-competitive inhibition of AMPA receptors
Keywords: AMPA; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate; CBF; cerebral blood flow; FDA; Food and drug administration; IL-1β; interleukin-1β; MCA; middle cerebral artery; NBQX; 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzol[f]quinoxaline; NMDA; N-methyl-d-a
Neuronal cell death due to glutamate excitotocity is mediated by P38 activation in the rat cerebral cortex
Keywords: AMPA; NMDA; GluR2; p38/SAPK; REST; Fas-L; Bcl-2
Differential response dynamics of corticothalamic glutamatergic synapses in the lateral geniculate nucleus and thalamic reticular nucleus
Keywords: EPSC; AMPA; GluR; thalamus; paired pulse facilitation; desensitizationACSF, artificial cerebrospinal fluid; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; EGTA, ethylene glycol-bis(b-aminoethyl ether)-N,N,N′,N′-tetraacetic acid; EPSC, excitat
Closing in on the AMPA receptor: Synthesis and evaluation of 2-acetyl-1-(4′-chlorophenyl)-6-methoxy-7-[11C]methoxy-1,2,3,4-tetrahydroisoquinoline as a potential PET tracer
Keywords: Glutamate; AMPA; PET; Isoquinolines; Carbon-11
Prepulse inhibition is different in two inbred mouse strains (CPB-K and BALB/cJ) with different hippocampal NMDA receptor densities
Keywords: AMPA; alpha-amino-3-hydroxy-5-methylisoxazole-4-proprionic acid; ASR; acoustic startle response to startle stimulus alone; NMDA; N-methyl-d-aspartate; NOSTIM; non-stimulus; PCP; phencyclidine; PPI; prepulse inhibition of the startle reflex; PREPULSE; prep
Repeated maternal separation of male Wistar rats alters glutamate receptor expression in the hippocampus but not the prefrontal cortex
Keywords: AMPA; NMDA; Development; mRNA; PCR; Stress;
Adenosine A1 receptors decrease thalamic excitation of inhibitory and excitatory neurons in the barrel cortex
Keywords: somatosensory; glutamate; interneurons; spiny stellate cells; ACSF; artificial cerebrospinal fluid; AHP; afterhyperpolarization; AMPA; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate; APV; dl-2-amino-5-phosphonopentanoic acid; CNQX; 6-cyano-7-nitroqu
Neuroprotective effect of topiramate on hypoxic ischemic brain injury in neonatal rats
Keywords: Cerebral ischemia; Oxygen–glucose deprivation; Neuroprotection; Topiramate; AMPA; Newborn
BMAA selectively injures motor neurons via AMPA/kainate receptor activation
Keywords: ALS; Amyotrophic lateral sclerosis; ALS/PDC; ALS–PDC; Guam; Motor neuron; Cell culture; Glutamate; AMPA; Ca2+; ROS; Cycad
Glutamate-dependent translational regulation in cultured Bergmann glia cells: Involvement of p70S6K
Keywords: p70S6K; glutamate receptors; Bergmann glia; mTOR; translational control; Akt I; 1L-6-hydroxymethyl-chiro-inositol 2-(R)-2-O-methyl-3-O-octadecylcarbonate; AMPA; amino α-3-hydroxy-5-methyl-4-isoaxazolepropionate; ANOVA; analysis of variance; BAPTA-AM; 1,2
Interleukin-1 beta modulates AMPA receptor expression and phosphorylation in hippocampal neurons
Keywords: IL-1β; Hippocampal neurons; AMPA; NMDA; Calcium; Phosphorylation; Glutamate receptor subunits
Effect of morphine on the release of excitatory amino acids in the rat hind instep: Pain is modulated by the interaction between the peripheral opioid and glutamate systems
Keywords: excitatory amino acids; small-diameter afferent fiber; axon-reflex; morphine; capsaicin; opioid receptor; AMPA; α-amino-3-hydroxy-5methyl-4-isoxazole propionic acid; DRG; dorsal root ganglion; EAA; excitatory amino acid; EST; electrical stimulation; GluR
AT4 receptor activation increases intracellular calcium influx and induces a non-N-methyl-d-aspartate dependent form of long-term potentiation
Keywords: theta burst stimulation; hippocampus; AT4 receptor; calcium uptake; Nle1-angiotensin IV; calcium channels; aCSF; artificial cerebrospinal fluid; agatoxin; Ï-agatoxin-TK; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionate; AngIV; angiotensin IV liga
Clinical neuroscienceCell swelling, seizures and spreading depression: An impedance study
Keywords: cerebral cortex; rat; fluorocitrate; kainic acid; picrotoxin; astroglia; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; EEG; electroencephalogram, electroencephalographic; SD; spreading depression; SDLE; spreading depression-like event;
Selectively increased sensitivity of cerebellar granule cells to AMPA receptor-mediated excitotoxicity in a mouse model of Batten disease
Keywords: Cerebellar granule cells; Cortical cultures; Cerebellar slice cultures; AMPA; Kainate; NMDA; Neuronal ceroid lipofuscinosis; Batten disease
Human autoantibodies against early endosome antigen-1 enhance excitatory synaptic transmission
Keywords: human autoantibodies; receptor endocytosis; early endosomes; AMPA; NMDA; kainateAMPAR, AMPA receptor; DMEM, Dulbecco’s Minimal Essential Medium; EEA1, early endosome antigen 1; EPSC, excitatory post-synaptic current; IB, immunoblotting; ICC, immunocytoche
Estrogen prevents glutamate-induced apoptosis in C6 glioma cells by a receptor-mediated mechanism
Keywords: calcium; calpain; caspase; estrogen receptor; glia; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; APV; dl-2-amino-5-phosphonopentanoic acid; BSA; bovine serum albumin; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; DAN; dantrolene; DMSO; dime
Metabotropic glutamate receptors mediate lipopolysaccharide-induced fever and sickness behavior
Keywords: Fever; Anorexia; Cachexia; LPS; Infection; NMDA; AMPA; Kainate; l(+)-AP3; Glutamate
Glutamate receptors and pain
Keywords: Glutamate; Pain; AMPA; NMDA; Kainate; Metabotropic glutamate receptor; Review
Regions of α-amino-5-methyl-3-hydroxy-4-isoxazole propionic acid receptor subunits that are permissive for the insertion of green fluorescent protein
Keywords: glutamate receptor subunit; green fluorescent protein; Tn5 transposon; AMPA receptor; fusion protein; insertional tagging; AMPA; α-amino-5-methyl-3-hydroxy-4-isoxazole propionic acid; ATD; amino terminal domain; CFP; cyan fluorescent protein; CTD; carbox
Transient rhythmic network activity in the somatosensory cortex evoked by distributed input in vitro
Keywords: rat; oscillation; afterdischarges; glutamate; GABA; gap junctions; ACSF; artificial cerebrospinal fluid; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole-proprionate; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; d-APV; d-2-amino-5-phosphonovalerate; ETNO; evo
Seeking a mechanism of action for the novel anticonvulsant lacosamide
Keywords: Lacosamide; GABAA; NMDA; AMPA; Voltage gated ion channels; Radioligand binding
Redistribution of synaptic AMPA receptors at glutamatergic synapses in the dorsal cochlear nucleus as an early response to cochlear ablation in rats
Keywords: ABR; Auditory brainstem response; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPAR; AMPA receptors; AN; auditory nerve; CwC; Cartwheel cells; CN; cochelar nuclei; DCN; dorsal cochlear nucleus; FC; Fusiform cells; GluRs; glutamate recepto
Developmental changes in presynaptic muscarinic modulation of excitatory and inhibitory neurotransmission in rat piriform cortex in vitro: Relevance to epileptiform bursting susceptibility
Keywords: piriform cortex; oxotremorine-M; presynaptic muscarinic modulation; depolarizing postsynaptic potentials; fast inhibitory postsynaptic potentials; development; AMPA; α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid; CNQX; 6-cyano-7-nitro-quinoxaline-
Modification of AMPA receptor properties following environmental enrichment
Keywords: Enriched environment; GluR2; GluR4; AMPA;
Involvement of ionotropic glutamate receptors in low frequency electroacupuncture analgesia in rats
Keywords: Electroacupuncture; NMDA; AMPA; KA;