دانلود مقالات ISI درباره Apap + ترجمه فارسی

Galangin's potential as a functional food ingredient

Keywords: Galangin; Propolis; Alpinia officinarum; Functional food ingredient; Polypharmacology; Flavonoid; AChE; acetylcholinesterase; AD; Alzheimer's disease; ADME; Administration, Distribution, Metabolism and Excretion; AHR; airway hyperresponsive; AhR; aryl h

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

In vitro evaluation of structural analogs of diallyl sulfide as novel CYP2E1 inhibitors for their protective effect against xenobiotic-induced toxicity and HIV replication

Keywords: CYP; cytochrome P450; APAP; acetaminophen; DAS; diallyl sulfide; AMS; allyl methyl sulfide; AES; allyl ethyl sulfide; DE; diallyl ether; TP; thiophene; PEA; 2-(prop-2-en-1-yloxy) ethan-1-amine; 5,1 HA; 5-hexen-1-amine; PEXA; 2-prop-2-enoxyacetamide; ROS;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Structural characterization, antioxidant and hepatoprotective activities of polysaccharides from Sophorae tonkinensis Radix

Keywords: STRP; Sophorae tonkinensis Radix polysaccharides; APAP; acetaminophen; FT-IR; fourier transform infrared; HPLC; high performance liquid chromatography; HPGPC; high performance gel permeation chromatography; GC-MS; gas chromatography and mass Spectrometr

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Fixed But Not Autoadjusting Positive Airway Pressure Attenuates the Time-dependent Decline in Glomerular Filtration Rate in Patients With OSA

Keywords: automatic CPAP; fixed CPAP; glomerular filtration rate; OSA; therapy; APAP; autoadjusting positive airway pressure; CKD; chronic kidney disease; eGFR; estimated glomerular filtration rate; ESADA; European Sleep Apnea Database; fCPAP; fixed CPAP; GFR; glom

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

A new bioluminescent imaging technology for studying oxidative stress in the testis and its impacts on fertility

Keywords: APAP; Acetaminophen; NAPQI; n-acetyl-p-benzoquinone imine; HCR; Hepatocellular carcinoma reporter; PCL-1; Peroxy Caged Luciferin-1; MDA; Malondialdehyde; SOD; Superoxide dismutase; GSH-Px; Glutathione peroxidase; GSH; Reduced glutathione; ROS; Reactive ox

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress, inflammation and apoptosis in mice

Keywords: 3-NT; 3-nitro-tyrosine; ALI; acute liver injury; ALT; alanine aminotransferase; APAP; acetaminophen; AST; aspartate aminotransferase; CAT; catalase; Cl-Cas-3; cleavage Caspase-3; CYP2E1; cytochrome P450 2E1; ERK1/2; extracellular signal-regulated kinase 1

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Natural product andrographolide alleviated APAP-induced liver fibrosis by activating Nrf2 antioxidant pathway

Keywords: APAP; acetaminophen; Nrf2; nuclear factor erythroid 2-related factor 2; Andro; andrographolide; HSCs; hepatic stellate cells; ROS; reactive oxygen species; ECMs; extracellular matrix proteins; Egr1; early growth factor 1; Keap1; kelch-like ECH-associated

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Effect of perfluorooctane sulphonate-induced Kupffer cell activation on hepatocyte proliferation through the NF-κB/TNF-α/IL-6-dependent pathway

Keywords: PFOS; Kupffer cells; Inflammation; Hepatocyte proliferation; NF-κB/ TNF-?/IL-6; ALT; alanine aminotransferase; AST; aspartate transaminase; APAP; acetaminophen; CCl4; carbon tetrachloride; CHE; cholinesterase; CM; conditioned media; CyD1; Cyclin D1; DAPI

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Circulating miRNAs in nontumoral liver diseases

Keywords: Ago; Argonaute; AFP; α-fetoprotein; AH; alcoholic hepatitis; AIH; autoimmune hepatitis; ALD; alcoholic liver disease; ALI; acute liver injury; ALT; alanine aminotransferase; AMA; antimitochondrial antibody; AP; alkaline phosphatase; APAP; acetaminophen;

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2018 سفارش ترجمه

Impact of obesity on the toxicity of a multi-ingredient dietary supplement, OxyELITE Pro™ (New Formula), using the novel NZO/HILtJ obese mouse model: Physiological and mechanistic assessments

Keywords: Cardiotoxicity; Herbal-induced liver injury; Hepatotoxicity; New dietary ingredient; OXYElite pro; Phytochemicals; ALT; alanine aminotransferase; APAP; acetaminophen; AST; aspartate aminotransferase; DILI; drug-induced liver injury; DILIN; Drug-Induced Li

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

Association of Variants of Arginine Vasopressin and Arginine Vasopressin Receptor 1A With Severe Acetaminophen Liver Injury

Keywords: Impulsivity; Stress Responsivity; Pituitary-Adrenal Axis; Overdose; ALF; acute liver failure; ALFSG; Acute Liver Failure Study Group; APAP; acetaminophen; SNP; single nucleotide polymorphism;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Screening of hepatoprotective compounds from licorice against carbon tetrachloride and acetaminophen induced HepG2 cells injury

Keywords: Licorice; Hepatoprotective; CCl4; Acetaminophen; Liver injury; CCl4; carbon tetrachloride; APAP; acetaminophen; DMSO; dimethyl sulfoxide; FBS; fetal bovine serum;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Glycyrrhetinic acid prevents acetaminophen-induced acute liver injury via the inhibition of CYP2E1 expression and HMGB1-TLR4 signal activation in mice

Keywords: APAP; acetaminophen; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CYP2E1; cytochrome P450 2E1; GSH; glutathione; ROS; reactive oxygen species; TNF-α; tumor necrosis factor-α; TLR4; toll like receptor 4; IRAKs; interleukin-1 receptor-a

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Serum microRNA-122-3p, microRNA-194-5p and microRNA-5099 are potential toxicological biomarkers for the hepatotoxicity induced by Airpotato yam

Keywords: miRNAs; microRNAs; ALT; alanine transaminase; AST; aspartate transaminase; EF; ethyl acetate fraction of Airpotato yam; DB; diosbulbin B; APAP; acetaminophen; MCT; monocrotaline; TSN; toosendanin; DILI; Drug-induced liver injury; WHO; World Health Organiz

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Trifluoperazine inhibits acetaminophen-induced hepatotoxicity and hepatic reactive nitrogen formation in mice and in freshly isolated hepatocytes

Keywords: APAP; Acetaminophen; NAPQI; N-Acetyl-p-benzoquinone imine; GSH; reduced glutathione; APAP-cys; 3-(cystein-S-yl)-acetaminophen; NO; Nitric Oxide; iNOS; Inducible nitric oxide synthase (NOS2); nNOS; Neuronal nitric oxide synthase (NOS1); GSNO; S-Nitrosoglut

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Sestrin2 protects against acetaminophen-induced liver injury

Keywords: Sestrin2; Acetaminophen; Oxidative stress; JNK; Ad-LacZ; adenovirus which expressed LacZ; Ad-Sesn2; adenovirus which expressed Sesn2; ALD; alcoholic liver diseases; ALT; alanine aminotransferase; APAP; acetaminophen; AST; aspartate aminotransferase; CYPs;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Generic method for the absolute quantification of glutathione S-conjugates: Application to the conjugates of acetaminophen, clozapine and diclofenac

Keywords: APAP; acetaminophen; CLZ; clozapine; DCF; diclofenac; GSH; glutathione; GST; glutathione S-transferases; HLM; human liver microsomes; KPi; potassium phosphate; NMR; nuclear magnetic resonance; NAC; N-acetylcysteine; OPA; o-phthaldialdehyde; TMSP; trimethy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Dynamic and accurate assessment of acetaminophen-induced hepatotoxicity by integrated photoacoustic imaging and mechanistic biomarkers in vivo

Keywords: ALI; acute liver injury; ALF; acute liver failure; miR-122; microRNA-122; HMGB1; High Mobility Group Box 1; TBIL; total bilirubin; ICG; indocyanine green; MSOT; multispectral optoacoustic tomography; PH; partial hepatectomy; APAP; acetaminophen; NAC; N-Ac

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Cell-free DNA in a three-dimensional spheroid cell culture model: A preliminary study

Keywords: cfDNA; cell-free DNA; 2D; two-dimensional; 3D; three-dimensional; LDH; lactate dehydrogenase; CE; capillary electrophoresis; APAP; acetaminophen; Cell-free DNA; 3D cell culture; Spheroid; Capillary electrophoresis; Rotating bioreactors;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Mass spectrometry based in vitro assay investigations on the transformation of pharmaceutical compounds by oxidative enzymes

Keywords: Pharmaceuticals; Enzymatic transformation; Peroxidase; Laccase; Transformation products; Mass spectrometry; ACN; acetonitrile; APAP; acetaminophen; BPA; bisphenol A; CBZ; carbamazepine; ESI; electrospray ionization; HRP; horseradish peroxidase; IBP; ibupr

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Activation of GR but not PXR by dexamethasone attenuated acetaminophen hepatotoxicities via Fgf21 induction

Keywords: APAP; acetaminophen; bp; base pair; ChIP; chromatin immunoprecipitation; Cyp; cytochrome p450 enzyme; DEX; dexamethasone; Fgf21; fibroblast growth factor 21; GR; glucocorticoid receptor; GRE; glucocorticoid receptor response element; GSH; Glutathione; i.p

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Long-term acetaminophen treatment induced liver fibrosis in mice and the involvement of Egr-1

Keywords: APAP; acetaminophen; Egr-1; early growth response 1; COL; collagen; TGF-β; transforming growth factor-β; α-SMA; α-smooth muscle actin; NAPQI; N-acetyl-p-benzoquinoneimine; ECMs; extracellular matrix proteins; OTC; over-the-counter; ALF; acute liver fa

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Galangin ameliorates cisplatin-induced nephrotoxicity by attenuating oxidative stress, inflammation and cell death in mice through inhibition of ERK and NF-kappaB signaling

Keywords: AKI; acute kidney injury; APAP; acetaminophen; APAP-GSH; acetaminophen glutathione conjugate; BUN; blood urea nitrogen; CAT; catalase; CREA; creatinine; ELISA; enzyme-linked immunosorbent assay; ERK1/2; extracellular signal-regulated kinase 1 and 2; GCLC;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Cytochrome P450-2E1 is involved in aging-related kidney damage in mice through increased nitroxidative stress

Keywords: Kidney; Aging; CYP2E1; Apoptosis; Fibrosis; Oxidative stress; APAP; acetaminophen; ATP5B; ATP synthase subunit Beta; CAT; catalase; Cytochrome P450; CYP; DNPH; dinitrophenylhydrazine; GCLC; glutamate-cysteine ligase catalytic subunit; GCLM; glutamate-cyst

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Safety assessment of the dietary supplement OxyELITE™ Pro (New Formula) in inbred and outbred mouse strains

Keywords: Dietary supplements; Drug-induced liver injury; Hepatotoxicity; Phytochemicals; ALT; alanine aminotransferase; APAP; acetaminophen; AST; aspartate aminotransferase; DILI; drug-induced liver injury; DILIN; Drug-Induced Liver Injury Network; DMAA; 1,3-dimet

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

A Review on Phytoconstituents and Biological activities of Cuscuta species

Keywords: MDA-MB-231; human caucasian breast adenocarcinoma; MCF-7; breast adenocarcinoma from human; Hep 3B; human hepatocellular carcinoma cell lines; HEK 293; human embryonic kidney cell lines; RAW 264.7; breast adenocarcinoma from human; DPPH; intercellular adh

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Acetaminophen (APAP) hepatotoxicity-Isn't it time for APAP to go away?

Keywords: Acetaminophen; Hepatotoxicity; APAP;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

3D in vitro models of liver fibrosis

Keywords: HSCs; hepatic stellate cells; ALT; alanine aminotransferase; APAP; acetaminophen; AST; aminotransferase; CBDL; common biled duct ligation; DAMPs; damage associated molecular patterns; DCM; decellularized matrix; DILI; drug-induced liver injury; ECM; extra

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Cystathionine beta-synthase deficiency alters hepatic phospholipid and choline metabolism: Post-translational repression of phosphatidylethanolamine N-methyltransferase is a consequence rather than a cause of liver injury in homocystinuria

Keywords: APAP; acetaminophen; ALT; alanine aminotransferase; BSO; buthionine sulfoximine; CCl4; carbon tetrachloride; HCU; classical homocystinuria; CCT; CTP:choline phosphate cytidylyltransferase; CBS; cystathionine beta-synthase; CGL; cystathionine gamma-lyase;

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2017 سفارش ترجمه

Hepatic hypoxia-inducible factors inhibit PPARα expression to exacerbate acetaminophen induced oxidative stress and hepatotoxicity

Keywords: ALT; alanine aminotransferase; APAP; acetaminophen; AST; aspartate aminotransferase; CCK8; Cell Counting Kit-8; DAB; 3,3′-diaminobenzidine; DAPI; 4′, 6-diamidino-2-phenylindole; DCFH-DA; 2′,7′-Dichlorofluorescein diacetate; DHE; dihydroethidium; D

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2017 سفارش ترجمه

Increased Expression of Cytotoxic T-Lymphocyte−Associated Protein 4 by T Cells, Induced by B7 in Sera, Reduces Adaptive Immunity in Patients With Acute Liver Failure

Keywords: Immune Regulation; Liver Disease; Treatment; Infection Susceptibility; AALF; acetaminophen-induced acute liver failure; ALF; acute liver failure; APAP; acetaminophen; CLD; chronic liver disease; CTLA4; cytotoxic T-lymphocyte−associated molecule-4; DC; d

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2017 سفارش ترجمه

Betaine homocysteine S-methyltransferase emerges as a new player of the nuclear methionine cycle

Keywords: AdoHcy; S-adenosylhomocysteine; AdoMet; S-adenosylmethionine; AGFC; analytical gel filtration chromatography; AHCY; S-adenosylhomocysteine hydrolase; APAP; acetaminophen; BHMT; betaine homocysteine methyltransferase; BSO; buthionine sulfoximine; EGSH; glu

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2017 سفارش ترجمه

MicroRNAs: New regulators of IL-22

Keywords: IL-22; interleukin-22; Th22; T helper 22 cell; Th1; T helper 1 cell; Th17; T helper 17 cell; NK22; natural killer 22; NKT; natural killer T cell; ILCs; innate lymphoid cells; RORγt; retinoid orphan receptor γt; STAT3; signal transducer and activator of

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Evaluation of microRNAs âˆ’ 208 and 133a/b as differential biomarkers of acute cardiac and skeletal muscle toxicity in rats

Keywords: APAP; acetaminophen; AAM; allylamine; AST; aspartate aminotransferase; cTnl; cardiac troponin; FABP3; fatty acid binding protein 3; ip; intraperitoneal; ISO; isoproterenol; MET; metaproterenol; miRNA; microribonucleic acid; MIT; mitoxantrone; MyL3; myosin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Serum microRNAs-217 and −375 as biomarkers of acute pancreatic injury in rats

Keywords: APAP; acetaminophen; Ct; cycle threshold; DPBS; Dulbecco's Phosphate-Buffered Saline; ip; intraperitoneal; miR; microRNA; po; oral gavage; STZ; streptozotocin; miRNA; Biomarker; Pancreatic; MiR-375; MiR-216a/b; MiR-217;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Inter-donor variability of phase I/phase II metabolism of three reference drugs in cryopreserved primary human hepatocytes in suspension and monolayer

Keywords: 4′-OH DF; 4′-hydroxy diclofenac; 5-OH DF; 5-hydroxy diclofenac; 7-HC; 7-hydroxycoumarin; APAP; acetaminophen; CYP; cytochrome P450; DMEM; Dulbecco's modified Eagle's medium; DF; diclofenac; OH-TC; hydroxy tolcapone; TC; tolcapone; GST; glutathione-S-t

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Clinical Course among Cases of Acute Liver Failure of Indeterminate Diagnosis

Keywords: APAP; Acetaminophen overdose; BIC; Bayesian information criteria; BLRT; Bootstrap likelihood ratio test; GMM; Growth mixture modeling; HE; Hepatic encephalopathy; IND; Indeterminate final diagnosis; INR; International normalized ratio; KCHC; King's Colleg

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

CPAP in the Perioperative Setting: Evidence of Support

Keywords: CPAP; OSA; perioperative period; AHI; apnea hypopnea index; APAP; autotitrated positive airway pressure; PACU; postanesthesia care unit; RCTs; randomized controlled trials; RR; risk reduction; SDB; sleep-disordered breathing;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Pathogenetic analyses of carbamazepine-induced liver injury in F344 rats focused on immune- and inflammation-related factors

Keywords: ALT; alanine aminotransferase; APAP; acetaminophen; ATP; adenosine triphosphate; BSO; l-buthionine S,R-sulfoximine; CBZ; carbamazepine; CD; cluster of differentiation; CV; centrilobular vein; CYP; cytochrome P450; DAMPs; damage-associated molecular patter

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Research paperHEI-OC1 cells as a model for investigating drug cytotoxicity

Keywords: HEI-OC1 cells; Cytotoxicity; Cell death; Cell viability; Cell senescence; Autophagy; HEK-293 cells; HeLa cells; HEI-OC1; House Ear Institute-Organ of Corti 1; APAP; N-acetyl-para-aminophenol/acetaminophen; BrdU; 5-Bromo-2′-deoxyuridine;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

PHLPP2 down regulation influences nuclear Nrf2 stability via Akt-1/Gsk3β/Fyn kinase axis in acetaminophen induced oxidative renal toxicity: Protection accorded by morin

Keywords: Acetaminophen; AN (analgesic nephropathy); Nrf2; Morin; Oxidative stress; PHLPP2; Fyn kinase; APAP; acetaminophen; ARE; antioxidant redox element; BUN; blood urea nitrogen; DCFH-DA; 2′,7′-dichlorofluorescein diacetate; DHE; dihydroethidium; ELISA; enz

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury

Keywords: APAP; Mouse Model; Gene Regulation; Pharmacologic TreatmentALF, acute liver failure; AMPK, adenosine monophosphate-activated protein kinase; APAP, acetaminophen; CCl4, carbon tetrachloride; D-GalN, D-galactosamine; DILI, drug-induced liver injury; IP, int

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Cardiolipin fatty acid remodeling regulates mitochondrial function by modifying the electron entry point in the respiratory chain

Keywords: CL; cardiolipin; ApAP; acetaminophen; MPCs; myeloid progenitor cells; CoQ; coenzyme Q; LC/ESI/MS/MS; liquid chromatography-electrospray ionization tandem mass spectrometry; L4CL; tetralinoleoyl-cardiolipin; LO3CL; linoleoyltrioleoyl-cardiolipin; M4CL; tet

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2016 سفارش ترجمه

Portable Monitoring for the Diagnosis of OSA

Keywords: obstructive sleep apnea; polysomnography; portable sleep studies; sleep-disordered breathing; sleep medicine; AASM; American Academy of Sleep Medicine; AHI; apnea/hypopnea index; APAP; autotitrating positive airway pressure; CHF; congestive heart failure;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms

Keywords: Akt PKB; protein kinase B; APAP; acetaminophen; ALT; alanine aminotransferase; ARE; antioxidant response element; β-Trcp; beta-transducin repeat containing protein; CDDO-Im; 1[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole; Cul3; cullin-3; DMSO;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

Combination of Mass Cytometry and Imaging Analysis Reveals Origin, Location, and Functional Repopulation of Liver Myeloid Cells in Mice

Keywords: CyTOF; DC; Liver Development; Mouse Model; APAP; acetaminophen; BM; bone marrow; CLL; clodronate-loaded liposomes; CyTOF; time-of-flight mass cytometry; DC; dendritic cell; GFP; green fluorescent protein; HSC; hepatic stellate cell; ICG; indocyanine green

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2016 سفارش ترجمه

Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are partially associated with the inhibition of CYP-mediated bioactivation

Keywords: ALT; alanine aminotransferase; APAP; acetaminophen; AST; aspartate aminotransferase; CYP; cytochrome P450; GSH; glutathione; NAPQI; N-acetyl-p-benzoquinone imine; SinA; Schisandrin A; SinB; Schisandrin B; SinC; Schisandrin C; SolA; Schisandrol A; SolB; Sc

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleMetformin ameliorates acetaminophen hepatotoxicity via Gadd45β-dependent regulation of JNK signaling in mice

Keywords: APAP; acetaminophen; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CAR; constitutive androstane receptor; CYP450; cytochrome P450; GSH; glutathione; Gadd45β; growth arrest and DNA damage-inducible 45 beta; JNK; c-Jun-N-terminal kinase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

The neuronal nitric oxide synthase inhibitor NANT blocks acetaminophen toxicity and protein nitration in freshly isolated hepatocytes

Keywords: APAP; Acetaminophen; NAPQI; N-Acetyl-p-benzoquinone imine; GSH; Reduced glutathione; APAP-cys; 3-(cystein-S-yl)-acetaminophen; NO; Nitric Oxide; iNOS; Inducible nitric oxide synthase (NOS2); nNOS; Neuronal nitric oxide synthase (NOS1); GSNO; S-Nitrosoglut

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Potential of extracellular microRNAs as biomarkers of acetaminophen toxicity in children

Keywords: miRNA; microRNA; DILI; drug induced liver injury; APAP; acetaminophen; ALT; alanine aminotransferase; ALF; acute liver failure; Acetaminophen; Pediatric; Urine; MicroRNA; DILI;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه