دانلود مقالات ISI درباره Ape1 + ترجمه فارسی

Cockayne Syndrome group B protein stimulates NEIL2 DNA glycosylase activity

Keywords: 5OHU; 5-hydroxyuracil; 8oxoG; 8-oxo-7,8-dihydro-2′-deoxyguanine; AP; abasic; APE1; AP-endonuclease-1; B11; 11bp bubble structure; BER; base excision repair; co-IP; Co-immunoprecipitation; control B11; cytosine in an 11 nucleotide bubble; CS; Cockayne Sy

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

A novel role for Gadd45α in base excision repair: Modulation of APE1 activity by the direct interaction of Gadd45α with PCNA

Keywords: Gadd45α; PCNA; APE1; Base excision repair (BER);

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

The influence of XPD, APE1, XRCC1, and NBS1 polymorphic variants on DNA repair in cells exposed to X-rays

Keywords: XPD; XRCC1; NBS; APE1; Polymorphism; DNA break repair; HCT116 cells; Cell cycle;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Differential effects of methoxyamine on doxorubicin cytotoxicity and genotoxicity in MDA-MB-231 human breast cancer cells

Keywords: DNA repair; Methoxyamine; Doxorubicin; Base excision repair; Micronuclei; APE1;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

APE1/Ref-1 prevents oxidative inactivation of ERK for G1-to-S progression following lead acetate exposure

Keywords: APE1; apurinic/apyrimidinic endonuclease 1; AsA; ascorbic acid; DTT; dithiothreitol; ELISA; enzyme-linked immunosorbent assay; ERK; extracellular signal-regulated kinase 1 and 2; GSH; glutathione; MBP; myelin basic protein; NAC; N-acetyl-l-cysteine; Pb; l

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Coordination of MYH DNA glycosylase and APE1 endonuclease activities via physical interactions

Keywords: 8-oxoG or Go; 7,8-dihydro-8-oxoguanine; 9-1-1; Rad9-Rad1-Hus1; AP; apurinic/apyrimidinic; APE1; AP-endonuclease 1; BSA; bovine serum albumin; BER; base excision repair; BstMutY; Bacillus stearothermophilus MutY; Ec-cMutY; Escherichia coli MutY cat

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Redox-regulating sirtuins in aging, caloric restriction, and exercise

Keywords: 8-oxoG, 8-oxo-7; 8-dihydroguanine; APE1; apurinic/apyrimidinic endonuclease 1; BER; DNA base excision repair; CR; caloric restriction; DSB; DNA double-strand break; FOXO; forkhead homeobox type O protein; eIF2α; eukaryotic initiation factor 2α; eNOS; en

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

8-Oxoguanine DNA glycosylase-1 links DNA repair to cellular signaling via the activation of the small GTPase Rac1

Keywords: 8-oxoG; 8-oxo-7,8-dihydroguanine; 8-oxodG; 8-oxo-7,8-dihydro-2′-deoxyguanosine; 8-OH-Ade; 8-oxo-7,8-dihydroadenine; APE1; apurinic/apyrimidinic endonuclease 1; DNA BER; base excision repair; FapyG; 2,6-diamino-4-hydroxy-5-formamidopyrimidine; FU; fluore

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

DNA repair mechanisms in dividing and non-dividing cells

Keywords: DNA repair; Neural cells; Neurological disorder; Dividing and non-dividing; Endogenous DNA damage; AOA1; ataxia with ocular motor apraxia 1; AP; apurinic/apyrimidinic; APE1; AP endonuclease 1; APTX; aprataxin; ATM; ataxia telangiectasia mutated; CPDs; cyc

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

Induction of base excision repair enzymes NTH1 and APE1 in rat spleen following aniline exposure

Keywords: Oxidative DNA damage; NTH1; APE1; DNA base excision repair; Aniline; Spleen

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Aerobic endurance capacity affects spatial memory and SIRT1 is a potent modulator of 8-oxoguanine repair

Keywords: 8-oxoG; 8-oxo-7,8-dihydroguanine; Ac; acetylated; AcOgg1; acetylated 8-oxoguanine DNA glycosylase-1; AP; abasic; APE1; apurinic apyrimidinic endonuclease1; BER; base excision repair; BrdU; 5-bromo-2′-deoxyuridine; DNPH; 4-dinitrophenylhydrazine; ERK; ex

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Acetylation on critical lysine residues of Apurinic/apyrimidinic endonuclease 1 (APE1) in triple negative breast cancers

Keywords: APE1; Apurinic/apyrimidinic endonuclease1; PTM; post-translational modification; nCaRE; negative calcium response elements; BER; base excision repair; TNBC; triple negative breast cancer; PARP; Poly(ADP-ribose) Polymerase; MMS; methyl-methanesulphonate; A

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Chinese hamster AP endonuclease operates by a two-metal ion assisted catalytic mechanism

Keywords: DNA repair; APE1; Two-metal ion; Lanthanum; Metal titration; Structural modelAPE, apurinic/apyrimidinic endonuclease; chAPE1, Chinese hamster apurinic/apyrimidinic endonuclease 1; BER, base excision repair; 5′-dRP, 5′ deoxyribose phosphate; polβ, DNA poly

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Autophagosome formation can be achieved in the absence of Atg18 by expressing engineered PAS-targeted Atg2

Keywords: ATG; autophagy-related; PAS; pre-autophagosomal structure; CVT; cytoplasm-to-vacuole targeting; Ape1; aminopeptidase I; prApe1; the proform of Ape1; mApe1; mature Ape1; PtdIns; phosphatidylinositol; PtdIns(3)P; phosphatidylinositol 3-phosphate; PtdIns(3,5

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Regulation of DNA repair by S-nitrosylation

Keywords: 8-oxoG; 8-oxoguanine; AGT; O6-alkylguanine-DNA-alkyltransferase; AP; apurinic-apyrimidinic; APE1; AP endonuclease 1; BER; base excision repair; DEN; diethylnitrosamine; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; DSB; double-strand break; DT

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Progress in high-throughput assays of MGMT and APE1 activities in cell extracts

Keywords: MGMT; O6-methylguanine; APE1; BER pathway; Phenotypic assay; Molecular epidemiology

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Impact of cadmium on hOGG1 and APE1 as a function of the cellular p53 status

Keywords: Cadmium; BER; OGG; APE1; p53

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

p300/CBP acetyl transferases interact with and acetylate the nucleotide excision repair factor XPG

Keywords: APE1; AP-endonuclease 1; BER; base excision repair; CBP; CREB-binding protein; CPD; cyclobutane pyrimidine dimers; FEN1; flap endonuclease 1; HAT; histone acetyltransferase; HDAC1; histone deacetylase 1; KAT; lysine acetyltransferase; MPG; methylpurine DN

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

CommentaryExtraneuronal activities and regulatory mechanisms of the atypical cyclin-dependent kinase Cdk5

Keywords: APE1; apurinic-apyrimidinic endonuclease 1; Cdk; cyclin-dependent kinase; Cdk5R1 or p35; Cdk5 regulatory protein R1; Cdk5R2 or p39; Cdk5 regulatory protein R2; EPRS; glutamyl-prolyl tRNA synthetase; E-Syt1; extended synaptotagmin-1; FAK; focal adhesion ki

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

The human gastric cancer-associated DNA polymerase β variant D160N is a mutator that induces cellular transformation

Keywords: Pol β; DNA polymerase β; BER; base excision repair; AP; apurinic/apyrimidinic; APE1; AP endonuclease 1; dRP; deoxyribose phosphate; NEIL; Nei-like; WT; wild-type; Tet; tetracycline; MEF; mouse embryonic fibroblast; Hyg; hygromycin; SDS; sodium dodecyl s

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Trypanosoma brucei AP endonuclease 1 has a major role in the repair of abasic sites and protection against DNA-damaging agents

Keywords: AP; apurinic/apyrimidinic; TBAPE1; Trypanosoma brucei AP endonuclease 1; LMAP; Leishmania major AP endonuclease; exoIII; exonuclease III; endoIV; endonuclease IV; OGG1; 8-oxoguanine DNA glycosylase 1; NTH1; endonuclease III; BSD; blasticidin S transferase

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Human AP endonuclease/redox factor APE1/ref-1modulates mitochondrial function after oxidative stress by regulating the transcriptional activity of NRF1

Keywords: APE1; apurinic/apyrimidinic endonuclease; ChIP; chromatin immunoprecipitation; COX; cytochrome c oxidase; DOX; doxycycline; EMSA; electrophoretic mobility-shift assay; ETC; electron transport chain; MMP; mitochondrial membrane potential; MT-CO1; mitochond

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

The excitatory neurotransmitter glutamate stimulates DNA repair to increase neuronal resiliency

Keywords: Glutamate; Excitotoxicity; Oxidative DNA damage; APE1; Neurodegenerative diseases

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Incidence and persistence of 8-oxo-7,8-dihydroguanine within a hairpin intermediate exacerbates a toxic oxidation cycle associated with trinucleotide repeat expansion

Keywords: 8-oxoG; 8-oxo-7,8-dihydroguanine; AP; apurinic; APE1; apurinic endonuclease 1; BER; base excision repair; BSA; bovine serum albumin; DMT; dimethoxytrityl; EDTA; ethylenediaminetetraacetic acid; FEN1; flap endonuclease 1; HD; Huntington's disease; hOGG1; h

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Base excision repair apurinic/apyrimidinic endonucleases in apicomplexan parasite Toxoplasma gondii

Keywords: BER; DNA damage; APE1; APN1; Protozoa; Malaria

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Endoribonuclease activity of human apurinic/apyrimidinic endonuclease 1 revealed by a real-time fluorometric assay

Keywords: Endoribonuclease; APE1; Fluorometric assay; Kinetics;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Benzene-derived N2-(4-hydroxyphenyl)-deoxyguanosine adduct: UvrABC incision and its conformation in DNA

Keywords: HQ; hydroquinone; p-BQ; p-benzoquinone; N2-4-HOPh-dG; N2-(4-hydroxyphenyl)-2'-deoxyguanosine; AP; apurinic/apyrimidinic; UvrABC; E. coli UvrABC complex; NER; nucleotide excision repair; BER; base excision repair; Exo III; exonuclease III; Endo IV; endon

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Variant base excision repair proteins: Contributors to genomic instability

Keywords: BER; base excision repair; ROS; reactive oxygen species; SAM; S-adenosylmethionine; APE1; apurimidinic endonuclease I; MTH; MutT homolog; OGG1; DNA glycosylase 8-oxoguanine glycosylase; FapyG; 2,6-diamino-4-hydroxy-5-formamidopyrimidine; 5-meC; 5-methylcy

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Inactivation by oxidation and recruitment into stress granules of hOGG1 but not APE1 in human cells exposed to sub-lethal concentrations of cadmium

Keywords: OGG1; APE1; Cadmium; Protein oxidation; Stress granules

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Human AP endonuclease 1 (APE1): From mechanistic insights to druggable target in cancer

Keywords: Cancer; Human AP endonuclease 1; APE1; Small molecule inhibitors

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Animal models of mitochondrial DNA transactions in disease and ageing

Keywords: mtDNA replication; mtDNA repair and recombination; Mitochondrial transcription; Animal models; Mouse; Drosophila; mtDNA; mitochondrial DNA; OXPHOS; oxidative phosphorylation system; ROS; reactive oxygen species; COX; cytochrome c oxidase; PD; Parkinson'

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Roles of Werner syndrome protein in protection of genome integrity

Keywords: γ-H2AX; phosphorylated histone H2AX; 4-NQO; 4-nitroquinoline 1-oxide; 5-OHdC; 5-hydroxycytidine; 5-OHU; 5-hydroxyuracil; 8-oxodA; 8-oxoadenine; 8-oxodG; 8-oxoguanine; ALT; alternative lengthening of telomeres; APE1; apurinic/apyrimidinic endonuclease 1;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Genetic polymorphisms in DNA repair gene APE1, XRCC1 and XPD and the risk of pre-eclampsia

Keywords: Preeclampsia; Polymorphism; DNA repair; APE1; XRCC1; XPD

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

APE1 overexpression is associated with cisplatin resistance in non-small cell lung cancer and targeted inhibition of APE1 enhances the activity of cisplatin in A549 cells

Keywords: Non-small cell lung cancer; APE1; Cisplatin; Chemotherapy; Adenoviral vector

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress: Use of APE1 small molecule inhibitors to delineate APE1 functions

Keywords: APE1; human apurinic (apyrimidinic) endonuclease/redox effector factor; WT-APE1; wild type APE1; C65-APE1; repair competent/redox deficient APE1; 177/226-APE1; repair deficient/redox competent APE1; MX; methoxyamine; BQP; 3-[5-(2,3-dimethoxy-6-methyl-1,4-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Single nucleotide polymorphisms in base-excision repair genes hOGG1, APE1 and XRCC1 do not alter risk of Alzheimer's disease

Keywords: Alzheimer's disease; Polymorphism; Base-excision repair; APE1; hOGG1; XRCC1

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease

Keywords: Ape1; Redox; Zebrafish; Evolutionary analysis; Crystal structure; Ref1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

AgingDNA repair in aging rat neurons

Keywords: aging; neurons; DNA repair; base excision repair; DNA polymerase β; non-homologous end joining; APE1; apurinic/apyrimidinic endonuclease-1; BER; base excision repair; dRp; 5′-deoxyribose phosphate; DSB; double strand break; FEN1; 'flap' structure s

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Slow base excision by human alkyladenine DNA glycosylase limits the rate of formation of AP sites and AP endonuclease 1 does not stimulate base excision

Keywords: DNA glycosylase; AP endonuclease; Base excision repair; Apurinic/apyrimidinic; Hypoxanthine; Ethenoadenine; 8-oxoG; 7,8-dihydro-8-oxo-2′deoxyguanosine; AAG; alkyladenine DNA glycosylase; AP; apurinic/apyrimidinic site; APE1; apurinic/apyrimidinic endonu

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Different organization of base excision repair of uracil in DNA in nuclei and mitochondria and selective upregulation of mitochondrial uracil-DNA glycosylase after oxidative stress

Keywords: base excision repair; oxidative stress; uracil-DNA glycosylase; repair complexes; mitochondria; AP; apyrimidinic; APE1; apurinic/apyrimidinic site endonuclease 1; APE2; apurinic/apyrimidinic site endonuclease 2; BER; base excision repair; CMV; cytomegalov

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Base excision repair and the central nervous system

Keywords: oxidative damage; DNA repair; brain; neurodegeneration; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APE1; AP endonuclease 1; BER; base excision repair; CAA; chloroacetaldehyde; d.p.c.; days post-coitum; dRP; 5′-deoxyribose phosphate;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2007 سفارش ترجمه

Association Between Polymorphisms in the DNA Repair Genes XRCC1 and APE1, and the Risk of Prostate Cancer in White and Black Americans

Keywords: prostate; prostatic neoplasms; polymorphism; genetic; continental population groups; DNA repair; APE1; apurinic/apyrimidic endonuclease; BER; base excision repair; PCR; polymerase chain reaction; RFLP; restriction fragment length polymorphism; ROS; reacti

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

Differential modulation of base excision repair activities during brain ontogeny: Implications for repair of transcribed DNA

Keywords: AP, apurinic/apyrimidinic; NEIL, Nei-like; 8-oxoG, 8-hydroxyguanine; OGG1, oxoguanine DNA glycosylase; 5-OHU, 5-hydroxyuracil; PNK, polynucleotide kinaseRat brain; Oxidative DNA damage; OGG1; APE1; NEIL1/2

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Alkylpurine-DNA-N-glycosylase excision of 7-(hydroxymethyl)-1,N6-ethenoadenine, a glycidaldehyde-derived DNA adduct

Keywords: GDA; glycidaldehyde; 7-hm-ɛA; 7-(hydroxymethyl)-1,N6-ethenoadenine; 8-hm-ɛC; 8(hydroxymethyl)-3,N4-ethenocytosine; ɛA; 1,N6-ethenoadenine; ɛC; 3,N4-ethenocytosine; AP; apurinic/apyrimidinic; APNG; alkylpurine-DNA-N-glycosylase; APE1; the major human A

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Inter-genomic cross talk between mitochondria and the nucleus plays an important role in tumorigenesis

Keywords: mtDNA; Mitochondrial DNA; CIN; Chromosomal instability; SKY; Spectral karyotyping; IHC; Immunohistochemistry; APE1; Apurinic/apyrimidinic endonuclease 1; TARP; Tissue arrays research program; Mitochondria; Inter-genomic; Nucleus; Chromosomal instability;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Effect of aging on intracellular distribution of abasic (AP) endonuclease 1 in the mouse liver

Keywords: APE1; Abasic site; Intracellular distribution; Mouse liver;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Action of human endonucleases III and VIII upon DNA-containing tandem dihydrouracil

Keywords: hNTH; human endonuclease III; NEIL1; human endonuclease VIII; APE1; human AP endonuclease; PNK; polynucleotide kinase; DHU; dihydrouracil; Clustered DNA damage; Tandem dihydrouracil; Human endonuclease III; Human endonuclease VIII; AP endonucleases; Polyn

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Molecular and biological roles of Ape1 protein in mammalian base excision repair

Keywords: Ape1; Base excision repair; 2-Deoxyribonolactone;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

DNA repair fidelity of base excision repair pathways in human cell extracts

Keywords: BER; base excision repair; AP site; apurinic/apyrimidinic site, abasic site; RAP; reduced abasic site; APE1; apurinic/apyrimidinic endonuclease 1; Pol β; DNA polymerase β; UDG; uracil-DNA glycosylase; XRCC1; X-ray repair cross-complementing protein-1;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

The Arg280His polymorphism in X-ray repair cross-complementing gene 1 impairs DNA repair ability

Keywords: XRCC1; X-ray repair cross-complementing gene 1; Pol-β; DNA polymerase-β; PARP-1; poly(ADP-ribose) polymerase 1; Lig III α; DNA ligase III α; APE1; apurinic/apyrimidinic endonuclease 1; CHO; Chinese hamster ovary; BER; base excision repair; SSBR; singl

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه