
Discovery and characterization of NVP-QAV680, a potent and selective CRTh2 receptor antagonist suitable for clinical testing in allergic diseases
Keywords: BAL; bronchoalveolar lavage; BEMP; 2-tert-butylimino-2-diethylamino-1,3-dimethyl-perhydro-1,3,2-diazaphosphorine; CCR-3; CC chemokine receptor 3; CRTh2; chemoattractant receptor homologous expressed on Th2 cells; DK-PGD2; 13,14-dihydro-15-keto-PGD2; ELSD;