Keywords: Mitochondrial dysfunction; Testosterone; Mitophagy; Hypogonadism; BNIP3; BCL2/adenovirus E1B 19â¯kDa protein-interacting protein 3; TA; tibialis anterior; ERK 1/2; extracellular signal-regulated kinase 1/2; AMPK; 5â² AMP-activated protein kinase; LC3;
مقالات ISI (ترجمه نشده)
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Keywords: ADAM; a disintegrin and metalloproteinase; AKT; protein kinase B; APAF 1; apoptotic protease activating factor 1; APC; adenomatous polyposis coli; ATG; autophagy protein; BAK; Bcl 2 homologous antagonist/killer; BAX; Bcl-2 associated -X protein; Bcl-2; B-
Keywords: ABC; ATP-binding cassette; AKT; V-Akt murine thymoma viral oncogene homolog; ALDH1; aldehyde dehydrogenase 1; AR; androgen receptor; Bad; Bcl-2-associated death promoter; Bak; Bcl-2 homologous antagonist killer; Bax; Bcl-2-associated X protein; Bcl-2; B-c
Keywords: Colon cancer; Anticancer; Fruit; Vegetable; Spice; Mechanism of action; Ang1; angiopoietin1; Bax; Bcl-2-associated X protein; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma-xL; CDKs; cyclin-dependent kinases; COX-2; cyclooxygenase-2; ERK; extracellular
Keywords: α-SMA; α-smooth muscle actin; AIF; apoptosis inducing factor; AP-1; activator protein 1; ARE; antioxidant response element; Bax; Bcl-2 associated X protein; Bcl-2; B-cell lymphoma 2; Bcl-xl; B cell lymphoma extra large; CDKCs; cyclin:CDK complexes; c-My
Keywords: ABCB1; ATP-binding cassette sub-family B member 1; ABCG; ATP-binding cassette drug efflux transporters; ACD; autophagic cell death; AKT; alpha serine/threonine protein kinase; ALDH; aldehyde dehydrogenase; AMPK; AMP-activated protein kinase; AP; apurinic/
Keywords: Greener synthesis; Capping agents; Metallic nanoparticles; Characterization; Biomedical applications; FTIR; Fourier transform infrared spectroscopy; AgNPs; silver nanoparticles; PdNPs; palladium nanoparticles; AuNPs; gold nanoparticles; BcL-xL; B-cell lym
Keywords: ALK1; activin receptor-like kinase1; ANG/Ang; angiopoietin; Bcl-xL; b-cell lymphoma-extra large; BM; bone marrow; BMDCs; bone marrow derived cells; BMP; bone morphogenetic protein; Bv8; bombina variagata peptide 8; CAFs; cancer/carcinoma associated fibrob
Keywords: 5-HT; serotonin (5-hydroxytryptamine); A83-01; TGF-β kinase/activin receptor-like kinase inhibitor; ACTB; actin beta/beta-actin; ASCL1; achaete-scute homolog 1 (MASH1); ASOs; anti-sense oligonucleotides; Bcl-xL; b-cell lymphoma-extra large; BDNF; brain d
Keywords: CuO-NPs; copper oxide nanoparticles; DLS; dynamic light scattering; PDI; polydispersity index; XRD; X-ray diffraction; HT-29; human colon cancer cell line; SW-620; human colon cancer cell line; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma-extra large
Keywords: ASH; American Society of Hematology; ATAP; amphipathic tail-anchoring peptide; BAD; BCL-2-associated death promoter protein; BAK; BCL-2 homologous antagonist killer; BAX; BCL-2-associated X protein; BCL-2; B-cell lymphoma 2; BCL-w (BCL2L2); BCL-2-like pro
Keywords: 53BP1; p53 binding protein 1; ACTH; adrenocorticotropic hormone; AIF; apoptosis-inducing factor; ATG5; autophagy-related 5; Bad; Bcl-2-associated death promoter; Bcl-2; B-cell lymphoma 2; Bcl-xL; B cell lymphoma extra-large; DSB; DNA double-strand break;
Keywords: ADP; adenosine diphosphate; ANT; adenine nucleotide translocator; ATP; adenosine triphosphate; Bax; BCL2-associated X protein; Bcl-xL; B-cell lymphoma-extra large; CLP; cecal ligation and puncture; CyP; cyclophilin; DAMP; damage-associated molecular patte
Keywords: Cd; cadmium; Zn; zinc; Cu; copper; CdCl2; cadmium chloride; bCd; whole blood Cd; bpCd; blood plasma Cd; sCd; serum Cd; spCd; seminal plasma Cd; uCd; urine Cd; 8 -OHdG; 8-hydroxy-2â²-deoxyguanosine; E2; estradiol; FSH; follicle stimulating hormone; T; tes
Keywords: PCD; programmed cell death; NC1; non-collagenous sequence 1; VEGFR1/2; vascular endothelial growth factor receptor 1/2; CAM; chick chorioallantoic membrane; MMPs; matrix metalloproteinases; GAP; GTPase-activating protein; FAK; focal adhesion kinase; MAPK;
Keywords: AB; amyloid beta; AD; Alzheimer's disease; AGE; advanced glycation end products; AKT; protein kinase B; BAD; Bcl 2 antagonist of death; BBB; blood brain barrier; Bcl-2; B-cell lymphoma 2; Bcl-XL; B-cell lymphoma extra large; Bim; Bcl-2 interacting media
Keywords: BAX; Bcl-2-associated X protein; BAK; Bcl-2-antagonist or killer; BID; Bcl-2 homology 3-interacting domain death agonist; Bcl-2; B cell lymphoma-2; Bcl-xL; B-cell lymphoma-extra large; VDAC-1; Voltage Dependent Anion Channel 1 porin; MOMP; mitochondrial o
Keywords: Iridovirus; Pro-apoptotic gene; Bax; Bak; Bcl-xL; Upregulation; Overexpression;
Keywords: ACI; Autologous chondrocyte implantation; ACPCs; Articular cartilage progenitor cells; ASCs; Adipose stem cells; BMP; Bone morphogenetic protein; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma-extra large; BCA-1; B cell-attracting chemokine 1; CCR6;
Keywords: BCL-XL; Myc/B cell extra-large; b.i; bone implant; BM; bone marrow; BMD; bone mineral density; Bort; bortezomib; β2M; β2Microglobulin; Car; carfilzomib; CP; cyclophosphamide; Dex; dexamethasone; DKK1; Dickkopf-1; Dox; doxorubicin; GFP; green fluorescent
Keywords: Akt; also known as protein kinase B; ANT; adenine nucleotide translocase; Bad; Bcl-2-associated death promoter; Bak; Bcl-2 homologous antagonist/killer; Bax; Bcl-2-like protein 4; Bcl2; B cell lymphoma 2; Bcl-xL; B-cell lymphoma-extra large; Bid; BH3 inte
Keywords: High-throughput screening; Protein-protein interaction inhibitor; Mcl-1; Bcl-xL; Hit compound validation;
Keywords: PDGF-A; platelet-derived growth factor-A; CK2; casein kinase 2; Bcl-2; B-cell lymphoma-2; PARP; poly-(ADP-ribose) polymerase; IAP; inhibitor of apoptosis protein; XIAP; X-linked inhibitor of apoptosis protein; 8-tBid; caspase-8-cleaved Bid; CBF1; C-repeat
Keywords: Glycolysis; Cancer; Cell death; GAPDH; Hexokinase; ANT; adenine nucleotide translocase; APAF-1; apoptotic protease activating factor-1; ATG5; autophagy related 5; ATP; adenosine triphosphate; Bak; Bcl-2 homologous antagonistic killer; Bax; Bcl-2-associate
Keywords: Epigenetics; Phytochemicals; DNA-methylation; Histone-modification; miRNA; Carcinogenesis; Akt; v-akt murine thymoma viral oncogene homolog 1; AP-1; Activator Protein-1; Bax; BCL2-associated X protein; Bcl2; B-cell CLL/lymphoma 2; Bcl-xL; B-cell lymphoma-
Keywords: Bcl-2; B cell lymphoma 2; Bcl-xL; B cell lymphoma-extra large; ARE; antioxidant-response element; Cul3; cullin 3; Cyt c; cytochrome c; Drp1; dynamin-related protein 1; ERK; extracellular signal-regulated kinase; GSH; glutathione; GST; glutathione S-tran
BMP4 signaling in NPCs upregulates Bcl-xL to promote their survival in the presence of FGF-2
Keywords: BMP4; Neural stem/progenitor cells; Survival; Id1; Bcl-xL; Fm; Serum-free medium containing FGF-2 alone; Bm; Serum-free medium containing BMP4 alone; FBm; Serum-free medium containing both FGF-2 and BMP4; Em; Serum-free medium containing EGF;
Discovery of Mcl-1 inhibitors based on a thiazolidine-2,4-dione scaffold
Keywords: Mcl-1; Bcl-xL; Apoptosis; Cancer; Protein-protein interaction;
Bcl-xL deamidation is regulated by multiple ion transporters and is intramolecularly catalyzed
Keywords: Bcl-xL; Deamidation; NHE; Histidine;
Ox40 regulates the conversion and suppressive function of double-negative regulatory T cells
Keywords: Tregs; regulatory T cells; DNT; double-negative regulatory T cells; mDCs; mature dendritic cells; KO; knockout; WT; wild type; Ox40-KO; Ox40 knockout; IL-2; interleukin 2; GM-CSF; granulocyte macrophage colony stimulating factor; CM; complete culture medi
A comparative study about EPA-PL and EPA-EE on ameliorating behavioral deficits in MPTP-induced mice with Parkinson's disease by suppressing oxidative stress and apoptosis
Keywords: EPA; eicosapentaenoic acid; PD; Parkinson's disease; Ï-3 LCPUFA; Omega-3 long chain polyunsaturated fatty acids; EPA-PL; eicosapentaenoic acid enriched phospholipids; EPA-EE; eicosapentaenoic acid-ethyl ester; DHA; docosahexaenoic acid; MPTP; 1-methyl-
Re-evaluating the role of FOXOs in cancer
Keywords: RTK; receptor tyrosine kinase; GF; growth factor; PI3K; Phosphatidylinositol-4,5-bisphosphate 3-kinase; PKB; protein kinase B; AKT; RAC-alpha serine/threonine-protein kinase; FOXO; forkhead box O; GFR; growth factor receptor; PDPK1; Phosphoinositide-depen
Design, synthesis and pharmacological evaluation of new acyl sulfonamides as potent and selective Bcl-2 inhibitors
Keywords: Bcl-2; Bcl-xL; Sulfonamide; Navitoclax; Apoptosis;
Proteins involved in the antioxidant and inflammatory response in rutin-treated human skin fibroblasts exposed to UVA or UVB irradiation
Keywords: AKT; protein kinase B; AMBIC; ammonium bicarbonate; Bad; Bcl-2-associated death promoter; Bax; bcl-2-like protein 4; Bcl-2; B-cell lymphoma 2 protein; Bcl-XL; B-cell lymphoma-extra-large protein; CCAR2; cell cycle/apoptosis regulator protein 2; DFF; DNA f
Strikingly Different Atheroprotective Effects of Apolipoprotein A-I in Early-Â Versus Late-Stage Atherosclerosis
Keywords: atherosclerosis; cholesterol; high-density lipoproteins; apoA-I; apolipoprotein A-I; apoEâ/â; apolipoprotein E deficient; Bcl-xL; B-cell lymphoma-extra large; HCAEC; human coronary artery endothelial cell; HDL; high-density lipoprotein; HFD; high-fat
Azilsartan and its Zn(II) complex. Synthesis, anticancer mechanisms of action and binding to bovine serum albumin
Keywords: 4CN; 4-chloro-1-naphthol; Ang II; angiotensin II; AO; acridine orange; ARBs; angiotensin receptor blockers; Azil; azilsartan; Bax; Bcl-2-associated X protein; Bcl-xL; B-cell lymphoma-extra large; BSA; bovine serum albumin; DCF; 2â²,7â²-dichlorofluoresce
The mechanism of tumour cell death by metal-based anticancer drugs is not only a matter of DNA interactions
Keywords: 15-LOX-1; 15-lipoxygenase; AIF; apoptosis inducing factor; APC; adenomatous polyposis coli; AKT or PKB; protein kinase B; ATG16L2; autophagy related 16 like 2; AUC; area under the curve; Bad; Bcl-2 associated death promoter; Bcl-2; B-cell lymphoma 2; Bcl-
Identification of a Bcl-xL homolog from orange-spotted grouper (Epinephelus coioides) involved in SGIV-induced nonapoptotic cell death
Keywords: Epinephelus coioides; Bcl-xL; Singapore grouper iridovirus (SGIV); Viral gene; Nonapoptotic cell death;
The pro-apoptotic protein Bmf co-operates with Bim and Puma in neuron death induced by β-amyloid or NGF deprivation
Keywords: Bmf; Bcl2 Modifying Factor; PUMA; p53 upregulated modulator of apoptosis; PC12; Pheochromocytoma cells; Bcl-2; B-cell lymphoma 2; BH3; Bcl-2 homology domain 3; Bim; Bcl-2 interacting mediator of cell death; Mcl-1; Myeloid cell leukemia 1; Bak; Bcl-2 antag
NF-κB in the crosshairs: Rethinking an old riddle
Keywords: BCL-2; B-cell lymphoma 2; BCL-XL; B-cell lymphoma-extra large; BFL-1; Bcl-2-related gene expressed in foetal liver; cIAP; cellular inhibitor of apoptosis; cFLIP; cellular FLICE-inhibitory protein; CLL; chronic lymphocytic leukaemia; DIABLO; direct inhibit
Schisandrin B exhibits potent anticancer activity in triple negative breast cancer by inhibiting STAT3
Keywords: Schisandrin B; STAT3; Apoptosis; Triple negative breast cancer; Bax; Bcl-2 associated protein x; Bcl-2; B-cell lymphoma 2; Bcl-xl; B-cell lymphoma-extra large; CDC2; cell division cycle 2; DAPI; 4, 6diamidino-2-phenylindole; DMSO; dimethylsulfoxide; FITC;
Flexibility enables to discriminate between ligands: Lessons from structural ensembles of Bcl-xl and Mcl-1
Keywords: Bcl-xl; Mcl-1; Conformational flexibility; Principal component analysis; Ligand binding;
Sulfiredoxin-1 enhances cardiac progenitor cell survival against oxidative stress via the upregulation of the ERK/NRF2 signal pathway
Keywords: SRXN1; sulfiredoxin-1; ALDH; aldehyde dehydrogenase; CoPP; Cobalt protoporphyrin; ÎΨm; mitochondrial membrane potential; BCL2; B-cell CLL/lymphoma 2; BCL-XL; BCL2-like 1; FACS; fluorescence-activated cell sorter; ALDHbr-hCPCs; aldehyde dehydrogenase bri
Role of Mcl-1 in regulation of cell death in human induced pluripotent stem cell-derived cardiomyocytes in vitro
Keywords: Mcl-1; Bcl-xL; hiPSC-cardiomyocyte; Mitochondria; Apoptosis; Cardio-oncology;
Hypertonicity-imposed BCL-XL addiction primes colorectal cancer cells for death
Keywords: Hyperosmotic stress; BH3 mimetics; BCL-XL; BCL-2; Apoptosis; BAK; BCL-2 antagonist or killer; BAX; BCL-2-associated X protein; CRC; colorectal cancer; MOMP; mitochondrial outer membrane permeabilization; OMM; outer mitochondrial membrane;
PGE2 induces apoptosis of hepatic stellate cells and attenuates liver fibrosis in mice by downregulating miR-23a-5p and miR-28a-5p
Keywords: COX-2; cyclooxygenase-2; PGE2; prostaglandin E2; ALT; alanine transaminase; TGF-β1; transforming growth factor β1; BAX; Bcl-2-associated X protein; Bcl-xL; B-cell lymphoma-extra-large; α-SMA; alpha smooth muscle actin; COL1A1; collagen type I alpha 1;
Exploring the selectivity of inhibitor complexes with Bcl-2 and Bcl-XL: A molecular dynamics simulation approach
Keywords: Bcl-2 family; Bcl-2; Bcl-XL; Selective inhibitors; Molecular dynamics;
Salidroside mediated stabilization of Bcl -xL prevents mitophagy in CA3 hippocampal neurons during hypoxia
Keywords: Hypoxia; Lipofuscin; Mitophagy; Bcl-xL; FUNDC1; Salidroside;
ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway
Keywords: Akt; oncogene in the transforming retrovirus, AKT8; AP-1; activator protein 1; ARAF; v-raf murine sarcoma 3611 viral oncogene homologue; ASK1; apoptosis signal-regulating kinase 1; BCL2; B-cell lymphoma 2; BCL-XL; B-cell lymphoma extra large; BRAF; v-raf
Expression, purification and characterization of hepatitis B virus X protein BH3-like motif-linker-Bcl-xL fusion protein for structural studies
Keywords: Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma extra large; BH3; Bcl-2 homology 3; HBV; hepatitis B virus; HBx; hepatitis B virus X protein; HCC; hepatocellular carcinoma; HSQC; heteronuclear single quantum coherence; BH3-like motif; Bcl-xL; Fusion pro