Synthesis of benzimidazole derivatives as potent β-glucuronidase inhibitors
Keywords: بنزیمیدازول; Benzimidazole; Synthesis; β-Glucuronidase; Docking studies;
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Novel 2-(2-phenalkyl)-1H-benzo[d]imidazoles as antitubercular agents. Synthesis, biological evaluation and structure–activity relationship
Keywords: بنزیمیدازول; Benzimidazole; Synthesis; Tuberculostatic activity; Anti-proliferative activity; SAR-study
Hypervalent iodine-mediated synthesis of benzoxazoles and benzimidazoles via an oxidative rearrangement
Keywords: بنزیمیدازول; Hypervalent iodine; Benzoxazole; Benzimidazole; Rearrangement; Bioactive compound;
Rapid selection for β-tubulin alleles in codon 200 conferring benzimidazole resistance in an Ostertagia ostertagi isolate on pasture
Keywords: بنزیمیدازول; Grazing cattle; Ostertagia ostertagi; SNP; Benzimidazole; Resistance; Pyrosequencing;
Dinuclear and polymeric (μ-formato)nickel(II) complexes: Synthesis, structure, spectral and magnetic properties
Keywords: بنزیمیدازول; Formato-nickel(II) complexes; Crystal structures; Benzimidazole; Tren-complexes; Magnetism
Synthesis, spectroscopic, DFT, cytotoxicity and antimicrobial activity of Pd(II) and Pt(II) complexes of N,N-chelated benzimidazole derivatives
Keywords: بنزیمیدازول; MCF7; Benzimidazole; Spectroscopic; DFT; MEP; NBO
Novel type of plasmin inhibitors: Providing insight into P4 moiety and alternative scaffold to pyrrolopyrimidine
Keywords: بنزیمیدازول; MMP; matrix metalloproteinase; UK; urokinase; pNA; para-nitroanilide; MCA; 7-amino-4-methyl-coumarin amide; Boc; t-butoxycarbonyl; Pyr; pyroglutamic acid; Plasmin inhibitors; Benzimidazole; Scaffold; Pyrrolopyrimidine; P4 moiety; Structure-activity rela
Synthesis and structural studies of amino amide salts derived from 2-(aminomethyl)benzimidazole and α-amino acids
Keywords: بنزیمیدازول; IWCQWGDXSBQSJG-UHFFFAOYSA-N; SJXWBRPWHPTQLQ-ZDUSSCGKSA-N; FWKPQKXMASWCGN-ZETCQYMHSA-NAmino amides; Benzimidazole; Hydrogen bonds; Crystallography; NMR; IR; QTAIM
V-shaped ligand 1,3-bis(1-ethylbenzimidazol-2-yl)-2-thiapropane and manganese(II), cobalt(II) and copper(II) complexes: Synthesis, crystal structure, DNA-binding properties and antioxidant activities
Keywords: بنزیمیدازول; Benzimidazole; Transition metal complex; Crystal structure; DNA-binding property; Antioxidant activity
Benzimidazole–ibuprofen/mesalamine conjugates: Potential candidates for multifactorial diseases
Keywords: بنزیمیدازول; Benzimidazole; 2-Aminobenzimidazole; Ibuprofen; Mesalamine; Anti-inflammatory; Immunomodulatory
Macrophage and colon tumor cells as targets for a binuclear silver(I) N-heterocyclic carbene complex, an anti-inflammatory and apoptosis mediator
Keywords: بنزیمیدازول; Benzimidazole; Benzimidazolium salts; N-heterocyclic carbenes (NHCs); Silver–NHC complexes; Anti-cancer; Anti-inflammatory
Synthesis, biological evaluation, and molecular docking studies of novel 1-benzene acyl-2-(1-methylindol-3-yl)-benzimidazole derivatives as potential tubulin polymerization inhibitors
Keywords: بنزیمیدازول; Tubulin polymerization inhibitors; N-methylindole; Benzimidazole; Molecular docking; 3D-QSAR;
Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole-benzimidazole derivatives
Keywords: بنزیمیدازول; Imidazo[2,1-b][1,3,4]thiadiazole; Benzimidazole; Mycobacterium tuberculosis; Antibacterial agent; Antioxidant activity; Cytotoxicity;
Discovery of novel, potent and low-toxicity angiotensin II receptor type 1 (AT1) blockers: Design, synthesis and biological evaluation of 6-substituted aminocarbonyl benzimidazoles with a chiral center
Keywords: بنزیمیدازول; Benzimidazole; Antihypertension; Chiral drug; Low-toxicity; Molecular docking;
Synthesis of 2-aryl-1,2,4-oxadiazolo-benzimidazoles: Tubulin polymerization inhibitors and apoptosis inducing agents
Keywords: بنزیمیدازول; Benzimidazole; 1,2,4-Oxadiazole; Cytotoxicity; Tubulin polymerization; Apoptosis; Molecular docking;
Benzimidazole derivatives as potential dual inhibitors for PARP-1 and DHODH
Keywords: بنزیمیدازول; Poly (ADP-ribose) polymerase; PARP; PARP-1; Dihydroorotate dehydrogenase; DHODH; Benzimidazole;
Novel 2,5-disubtituted-1,3,4-oxadiazoles with benzimidazole backbone: A new class of β-glucuronidase inhibitors and in silico studies
Keywords: بنزیمیدازول; Benzimidazole; Oxadiazole; β-Glucuronidase activity; In silico studies;
Structure activity relationship (SAR) study of benzimidazole scaffold for different biological activities: A mini-review
Keywords: بنزیمیدازول; Anthelmintics; Benzimidazole; Heterocyclic ring systems; Pharmacological activities; SAR study; NPY; neuropeptide; CYP450; cytochrome P450; HBV; hepatitis B virus; HCV; hepatitis C virus; RSV; respiratory syncytial virus; VV; varicella virus; BVDV; bovine
Design, synthesis and biological evaluation of 1,3-diphenyl-1H-pyrazole derivatives containing benzimidazole skeleton as potential anticancer and apoptosis inducing agents
Keywords: بنزیمیدازول; Pyrazole; Benzimidazole; Anti-proliferative activity; Apoptosis; RT-PCR;
Benzimidazole CB2 agonists: Design, synthesis and SAR
Keywords: بنزیمیدازول; CB2 agonist; Cannabinoid 2 receptor; Benzimidazole;
Relay recognition by modulating ESIPT: A phenylbenzimidazole derived sensor for highly selective ratiometric fluorescent recognition of Zn2+ and S2â in water
Keywords: بنزیمیدازول; Zinc recognition; Sulfide recognition; Benzimidazole; ESIPT; Ratiometric;
Conversion of zeolite—A in to various ion-exchanged catalytic forms and their catalytic efficiency for the synthesis of benzimidazole
Keywords: بنزیمیدازول; Benzimidazole; Catalysis; Characterization; Zeolite-A
In vitro-in vivo activity relationship of substituted benzimidazole cell division inhibitors with activity against Mycobacterium tuberculosis
Keywords: بنزیمیدازول; Mycobacterium tuberculosis; Benzimidazole; In vivo efficacy; FtsZ inhibitor; Murine model tuberculosis; In vitro activity;
The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target
Keywords: بنزیمیدازول; Enoyl reductase; Triclosan; Toxoplasma; Benzimidazole;
Uptake of benzimidazoles by Trichuris suis in vivo in pigs
Keywords: بنزیمیدازول; Trichuris trichiura; Trichuris suis; Benzimidazole; Drug-uptake; Treatment efficacy
Synthesis, characterization and antimicrobial activity of silver(I) complexes of hydroxymethyl derivatives of pyridine and benzimidazole
Keywords: بنزیمیدازول; Silver(I) complexes; Pyridine; Benzimidazole; X-ray diffraction; Antimicrobial activity
Synthesis, crystal structure and properties of benzimidazole-bridged dinuclear ferrocenyl derivatives
Keywords: بنزیمیدازول; Benzimidazole; Ferrocene (Fc); Crystal structure; Cyclic voltammetry; Catalytic effect
Eco-friendly synthesis of 2-aryl-1-arylmethyl-1H-benzimidazoles using alumina-sulfuric acid as a heterogeneous reusable catalyst
Keywords: بنزیمیدازول; Supported Bronsted acid; Benzimidazole; Catalysis; Solvent effects; Isotope labelling;
Synthesis, interaction with DNA and antiproliferative activities of two novel Cu(II) complexes with Schiff base of benzimidazole
Keywords: بنزیمیدازول; 5-Chlorosalicylaldehyde Schiff base; Benzimidazole; Copper complex; DNA binding; Antiproliferative activity
Benzimidazoles as new scaffold of sirtuin inhibitors: Green synthesis, in vitro studies, molecular docking analysis and evaluation of their anti-cancer properties
Keywords: بنزیمیدازول; Sirtuin; Benzimidazole; Anti-proliferative; Green chemistry synthesis
Structural and spectral properties of a zinc(II) coordination polymer: A combined experimental and theoretical study
Keywords: بنزیمیدازول; Coordination polymer; Benzimidazole; Crystal structure; Fluorescence; TDDFT;
Synthesis, characterization and coordination properties of 2-(2′-(methylseleno)phenyl)benzimidazole
Keywords: بنزیمیدازول; Benzimidazole; Selenoether; Palladium(II) complex; Platinum(II) complex; Intermolecular interaction
Cationic iron(II) complexes of the mixed cyclopentadienyl (Cp) and the N-heterocyclic carbene (NHC) ligands as effective precatalysts for the hydrosilylation of carbonyl compounds
Keywords: بنزیمیدازول; Iron; NHC ligands; Benzimidazole; Imidazole; Hydrosilylation
Synthesis of novel derivatives of 4-methylbenzimidazole and evaluation of their biological activities
Keywords: بنزیمیدازول; Benzimidazole; Antiglycation; Antioxidant; Antileishmanial; Stereoisomers
Vapour pressures of 1-methyl derivatives of benzimidazole, pyrazole and indole. The energy of the intermolecular hydrogen bond NH⋯N
Keywords: بنزیمیدازول; Vapour pressures; 1-Methylbenzimidazole; 1-Methylpyrazole; 1-Methylindole; Imidazole; Benzimidazole; Pyrazole; Enthalpy of sublimation; Entropy of sublimation; Enthalpy of vaporisation; Entropy of vaporisation; Temperature of fusion; Enthalpy of fusion; E
Organic–inorganic hybrid proton exchange membrane based on polyhedral oligomeric silsesquioxanes and sulfonated polyimides containing benzimidazole
Keywords: بنزیمیدازول; Proton exchange membrane; Sulfonated polyimide; Benzimidazole; Cross-linked; Glycidyl ether of polyhedral oligomeric silsesquioxanes
Engineering polar crystal structures by Ï-Ï stacking of N-perfluoroarylbenzimidazoles
Keywords: بنزیمیدازول; Benzimidazole; Polyfluoroarene; Ï-Ï Stacking; Polar crystal structure;
Cyanovinyl substituted benzimidazole based (D–π–A) organic dyes for fabrication of dye sensitized solar cells
Keywords: بنزیمیدازول; Benzimidazole; Cyanovinyl; Organic dye; Efficiency; π-bridge; Acceptor
Tuning the photophysical and electrochemical properties of iridium(III) 2-aryl-1-phenylbenzimidazole complexes
Keywords: بنزیمیدازول; Iridium(III) complexes; Benzimidazole; Cyclometalation; Electrochemical studies; DFT calculation; Absorption spectra
Neutral heteroleptic rhenium-based M3L3L′ type metallacycles: Synthesis, structural characterization and DFT/TDDFT studies
Keywords: بنزیمیدازول; Benzimidazole; Benzotriazole; Metallacalix[3]arene; Rhenium; Tripodal N donor
Phenotypic and genotypic characterisation of Haemonchus spp. and other gastrointestinal nematodes resistant to benzimidazole in infected calves from the tropical regions of Campeche State, Mexico
Keywords: بنزیمیدازول; Calves; Benzimidazole; Nematodes; FECRT; PCR; β-Tubulin;
Discovery of a benzimidazole series of ADAMTS-5 (aggrecanase-2) inhibitors by scaffold hopping
Keywords: بنزیمیدازول; ADAMTS-5; Benzimidazole; Thiazolidin-4-one; Inhibitor; Osteoarthritis
Discovery of quinazolin-4-amines bearing benzimidazole fragments as dual inhibitors of c-Met and VEGFR-2
Keywords: بنزیمیدازول; Quinazoline; Benzimidazole; Dual inhibitor; c-Met; VEGFR-2
Mn(II) complexes of a tridentate benzimidazole ligand: Synthesis, structural characterisation and catalase mimetic studies
Keywords: بنزیمیدازول; Manganese; Benzimidazole; X-ray crystallography; Counter ion; Catalase;
Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors
Keywords: بنزیمیدازول; Podophyllotoxin; Benzimidazole; Cytotoxicity; Tubulin polymerization; Molecular docking;
Discovery of N-(2-phenyl-1H-benzo[d]imidazol-5-yl)quinolin-4-amine derivatives as novel VEGFR-2 kinase inhibitors
Keywords: بنزیمیدازول; VEGFR-2 kinase inhibitor; Antitumor; Quinolin; Benzimidazole
Synthesis of C-xylopyranosyl- and xylopyranosylidene-spiro-heterocycles as potential inhibitors of glycogen phosphorylase
Keywords: بنزیمیدازول; Xylose derivative; Benzimidazole; 1,2,4-Triazole; Spiro-isoxazoline; Spiro-1,4,2-oxathiazole; Glycogen phosphorylase inhibitor
Design, synthesis and evaluation of novel 2,5,6-trisubstituted benzimidazoles targeting FtsZ as antitubercular agents
Keywords: بنزیمیدازول; Tuberculosis; Antibacterial; FtsZ; Benzimidazole;
Novel benzimidazole derivatives as phosphodiesterase 10A (PDE10A) inhibitors with improved metabolic stability
Keywords: بنزیمیدازول; PDE10A inhibitor; Schizophrenia; Benzimidazole; Imidazopyridine; Metabolic stability;
Benzimidazole: An emerging scaffold for analgesic and anti-inflammatory agents
Keywords: بنزیمیدازول; Analgesic; Benzimidazole; Cyclooxygenase-2 (COX-2) inhibitors; Non-steroidal anti-inflammatory drugs (NSAIDs)