دانلود مقالات ISI درباره ترمیم برداشت بازی + ترجمه فارسی

تأثیرات اختلاف ژنوتیپ در تولید امواج رادیوتراپی متابولومیک ادرار

Implications of genotypic differences in the generation of a urinary metabolomics radiation signature

Keywords: ترمیم برداشت بازی; IR, ionizing radiation; LC, liquid chromatography; MS, mass spectrometry; TCA, tricarboxylic acid; WT, wild type; CT, computed tomography; PARP1, poly(ADP-ribose)polymerase 1; BER, base excision repair; SIRT1, sirtuin-1; D1, day 1; D3, day 3; HMDB, the Hu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

روشهای کشنده مصنوعی برای ارزیابی اثر ترکیبی داروهای شیمی درمانی

Synthetic lethal approaches for assessing combinatorial efficacy of chemotherapeutic drugs

Keywords: ترمیم برداشت بازی; Synthetic lethality; Epigenetics; High-throughput screening; Genomics; Signaling networksATM, ataxia telangiectasia, mutated; ATR, ATM and Rad3-related; ATRIP, ATR-interacting protein; BAF, Brg1-associated factor; BER, base excision repair; BRCA1, breast

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

شبکه زیست شناسی ردوکس در پاتوفیزیولوژی سرطان و درمان

The redox biology network in cancer pathophysiology and therapeutics

Keywords: ترمیم برداشت بازی; BER, base excision repair; CSC, cancer stem cells; DAMPs, danger-associated molecular patterns; DDR, DNA damage response; EGFR, epidermal growth factor receptor; HMGB1, high-mobility Group Box 1; HR, homologous recombination repair; IR, ionizing radiation

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

نقش بازسازی پایه در ایجاد گلوکوم زاویه باز اولیه در جمعیت لهستانی

The role of base excision repair in the development of primary open angle glaucoma in the Polish population

Keywords: ترمیم برداشت بازی; POAG, primary open angle glaucoma; hTM, human trabecular meshwork; RGC, retinal ganglion cell; BER, base excision repair; ROS, reactive oxygen species; IOP, increase intraocular pressure; CNS, central nervous system; AP site, the apurinic/apyrimidinic (AP

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

اثر دوز کم دوز تابش یونیزه بر سلول های بنیادی بافت نرم

Low dose effects of ionizing radiation on normal tissue stem cells

Keywords: ترمیم برداشت بازی; Normal stem cells; Irradiation; Low dose; CarcinogenesisAPE1, Apurinic endonuclease; ATM, ataxia telangiectasia mutated; BER, base excision repair; CSC, cancer stem cell; DNA DSB, DNA double strand break; ESC, Embryonic stem cell; EMT, Epithelial-to-Mesen

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

پلیمورفیسم ژن مرتبط با تعمیرات تخریب ناقلین ها و حساسیت ژنتیکی، حساسیت شیمی درمانی و پیش آگهی سرطان معده

Nucleotide excision repair related gene polymorphisms and genetic susceptibility, chemotherapeutic sensitivity and prognosis of gastric cancer

Keywords: ترمیم برداشت بازی; NER, nucleotide excision repair; GC, gastric cancer; BER, base excision repair; MMR, mismatch repair; DSBR, double-strand break repair; GGNER, global genome nucleotide excision repair; TCNER, transcription-coupled nucleotide excision repair; GCA, gastric

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

اپی ژنتیک و تنظیم آسیب پذیری و انعطاف پذیری استرس

Epigenetics and the regulation of stress vulnerability and resilience

Keywords: ترمیم برداشت بازی; 5hmC, 5-hydroxymethyl cytosine; 5mC, 5-methyl cytosine; ACTH, adrenocorticotropin hormone; AVP, arginine vasopressin; BDNF, Brain-Derived Neurotrophic Factor; BER, base excision repair; Crf, Corticotrophin-Releasing Factor; CUMS, chronic ultra mild stress

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

نشانه های پیری فیبروبلاست

The hallmarks of fibroblast ageing

Keywords: ترمیم برداشت بازی; 6-4PP, 6-4 pyrimidine–pyrimidone photoproducts; AHR, Aryl hydrocarbon receptor; AP-1, heterodimeric transcription factor belonging to the c-fos/c-jun families; ARNT, arylhydrocarbon receptor nuclear translocator; BER, base excision repair; CCN1, cysteine-

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2014 سفارش ترجمه

Decreased DNA repair gene XRCC1 expression is associated with radiotherapy-induced acute side effects in breast cancer patients

Keywords: ترمیم برداشت بازی; XRCC1, X-ray repair cross complementing group 1; PARP1, Poly (ADP-ribose) polymerase 1; BER, base excision repair; RT-qPCR, Reverse transcriptase-quantitative polymerase chain reaction; MN, MicronucleusAcute side effects; breast cancer; DNA damage; DNA re

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Uridine homeostatic disorder leads to DNA damage and tumorigenesis

Keywords: ترمیم برداشت بازی; ATM, ataxia telangiectasia mutated; ATP, adenosine triphosphate; ATR, ATM-Rad3-related; BER, base excision repair; CTP, cytidine 5′-triphosphate; DAPI, 4′,6-diamidino-2-phenylindole; dCDP, deoxycytidine 5′-diphosphate; dCTP, deoxycytidine 5′-triphosphate;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Human DNA repair disorders in dermatology: A historical perspective, current concepts and new insight

Keywords: ترمیم برداشت بازی; BER, base excision repair; COFS, cerebro–oculo–facio-skeletal syndrome; CPD, cyclobutane pyrimidine dimers; CS, Cockayne syndrome; FA, Fanconi anemia; GG-NER, global genome repair; NER, nucleotide excision repair; 6–4 PP, pyrimidine (6–4) pyrimidone photo

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Quantification of the mutagenic potency and repair of glycidol-induced DNA lesions

Keywords: ترمیم برداشت بازی; ADU, alkaline DNA unwinding; 4-ANI, 4-amino-1,8-naphtalamide; BER, base excision repair; CHO, Chinese ovary cells; DRAG, detection of repairable adducts through growth inhibition; Gly, glycidol; HPRT, hypoxanthine phosphoribosyltransferase; HR, homologous

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

A computational approach to determine susceptibility to cancer by evaluating the deleterious effect of nsSNP in XRCC1 gene on binding interaction of XRCC1 protein with ligase III

Keywords: ترمیم برداشت بازی; BER, base excision repair; DDG, Gibbs free energy change; GO, gene ontology; LIG3, ligase III; NER, nucleotide excision repair; NHEJ, non-homologous end joining; nsSNPs, non-synonymous single nucleotide polymorphisms; PDB, Protein Data Bank; RI, reliabili

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Ku antigen displays the AP lyase activity on a certain type of duplex DNA

Keywords: ترمیم برداشت بازی; AP site, apurinic/apyrimidinic site; APE1, apurinic/apyrimidinic endonuclease 1; BER, base excision repair; dRP, deoxyribose phosphate; DSB, double-strand break; Endo III, Escherichia coli endonuclease III; GAPDH, glyceraldehyde-3-phosphate dehydrogenase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Breast cancer 1 (BRCA1)-deficient embryos develop normally but are more susceptible to ethanol-initiated DNA damage and embryopathies

Keywords: ترمیم برداشت بازی; 8-oxo-2′-deoxyguanosine, 8-oxodGuo; BER, Base excision repair; brca1, Breast cancer 1; csb, Cockayne Syndrome B; dGuo, deoxyguanosine; DSB, double strand break; ELISA, enzyme linked immunosorbent assay; EtOH, ethanol; FASD, fetal alcohol spectrum disorder

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Interaction between APC and Fen1 during breast carcinogenesis

Keywords: ترمیم برداشت بازی; Adenomatous polyposis coli; Flap endonuclease 1; Base excision repair; Environmental carcinogens; Breast cancer development; MortalityAAG/MPG, alkyladenine; APC, adenomatous polyposis coli; BER, base excision repair; DRI, DNA-repair inhibitory; EGFR, epid

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

SNF2H interacts with XRCC1 and is involved in repair of H2O2-induced DNA damage

Keywords: ترمیم برداشت بازی; AP sites, apurinic/apyrimidinic sites; BER, base excision repair; CBB, Coomassie Brilliant Blue; CK2, , casein kinase 2; DSB, double-strand break; OGG1, 8-oxoguanine DNA glycosylase; PAR, poly(ADP-ribose); PARP, poly(ADP-ribose) polymerase; SNF2H, sucrose

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Two stages of XRCC1 recruitment and two classes of XRCC1 foci formed in response to low level DNA damage induced by visible light, or stress triggered by heat shock

Keywords: ترمیم برداشت بازی; BER, base excision repair; DSB, double-strand DNA break; IF, immunofluorescence; mJ, milliJoul; MMS, methyl methane sulfonate; NB, nuclear (subnuclear) body; PAR, poly(ADP-ribose); PML, promyelocytic leukemia; RIF, radiation-induced foci; SSB, single-stra

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

The Corynebacterium pseudotuberculosis genome contains two formamidopyrimidine-DNA glycosylase enzymes, only one of which recognizes and excises 8-oxoguanine lesion

Keywords: ترمیم برداشت بازی; BER, base excision repair; AP, apurinic/apyrimidinic; MutM, formamidopyrimidine-DNA glycosylase; ROS, reactive oxygen species; H2TH, helix–two-turn–helix; PDB, Protein Data Bank; OD, optical density; IPTG, isopropyl b-d-thiogalactopyranoside; PAGE, polyac

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

POLD1: Central mediator of DNA replication and repair, and implication in cancer and other pathologies

Keywords: ترمیم برداشت بازی; ATR, Ataxia Telangiectasia and Rad3-related protein; AWS, atypical Werner syndrome; BER, base excision repair; BIR, break-induced recombination; bMMRD, biallelic mismatch repair deficiency; CIA, cytosolic iron–sulfur protein assembly; CRC, colorectal canc

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

DNA damage in Fabry patients: An investigation of oxidative damage and repair

Keywords: ترمیم برداشت بازی; BER, base excision repair; DCF, dichlorofluorescein; DCFH, dihydrodichlorofluorescein; DI, damage index; EndoIII, endonuclease III; ERT, enzyme replacement therapy; FD, Fabry disease; FPG, formamidopyrimidine DNA-glycosylase; Gb3, globotriaosylceramideFab

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

New structural snapshots provide molecular insights into the mechanism of high fidelity DNA synthesis

Keywords: ترمیم برداشت بازی; 1-nt, 1-nucleotide; AP, apurinic/apyrimidinic; BER, base excision repair; dNTP, deoxynucleoside triphosphate; dRP, deoxyribose phosphate; Mc, catalytic metal; Mg, ground state metal; Mn, nucleotide or transition state metal; Mp, product metal; PPi, pyroph

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Accessing DNA damage in chromatin: Preparing the chromatin landscape for base excision repair

Keywords: ترمیم برداشت بازی; BER, base excision repair; NCP, nucleosome core particle; SP-BER, short-patch base excision repair; LP-BER, long-patch base excision repair; UDG, uracil DNA glycosylase; AP, apurinic/apyrimidinic; APE, AP endonuclease; PNKP, polynucleotide kinase/phosphat

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

The association of folate pathway and DNA repair polymorphisms with susceptibility to childhood acute lymphoblastic leukemia

Keywords: ترمیم برداشت بازی; ALL, acute lymphoblastic leukemia; BER, base excision repair; CI, confidence intervals; dHPLC, denaturing high performance liquid chromatography; DSBs, double strand breaks; dTMP, deoxythymidine monophosphate; dTTP, deoxythymidine triphosphate; GWA, genom

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Genetic variants in the DNA repair gene NEIL3 and the risk of myocardial infarction in a nested case–control study. The HUNT Study

Keywords: ترمیم برداشت بازی; BER, base excision repair; SNP, single nucleotide polymorphism; MI, myocardial infarction; ROS, reactive oxygen species; AP, apurinic/apyrimidinic; BMI, body mass index; HUNT, Helseundersøkelsen i Nord-Trøndelag/Nord-Trøndelag Health Study; HDL, high-dens

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Polychlorinated biphenyl quinone induces oxidative DNA damage and repair responses: The activations of NHEJ, BER and NER via ATM-p53 signaling axis

Keywords: ترمیم برداشت بازی; 8-OHdG, 8-hydroxy-2′-deoxyguanosine; AP, apurinic/apyrimidinic; APE1, AP endonuclease 1; ATM, ataxia telangiectasia mutated; ATR, ATM Rad3-related protein; BER, base excision repair; DNA-PKcs, DNA-dependent protein kinases; ERCC1, excision repair cross-co

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Tissue specific response to DNA damage: C. elegans as role model

Keywords: ترمیم برداشت بازی; BER, base excision repair; CO, crossover; DDR, DNA damage response; DSB, double strand break; FA, Fanconi anemia; GG-NER, global genome nucleotide excision repair; HR, homologous recombination; ICLR, interstrand-crosslink repair; IR, ionizing radiation; N

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

The role of oxidative DNA damage in radiation induced bystander effect

Keywords: ترمیم برداشت بازی; AP-1, activation protein-1; ARF, alternative reading frame; ATM, ataxia-telangiectasia mutated; ATR, ataxia-telangiectasia mutated Rad3-related; BER, base excision repair; Cdc6, cell division cycle 6; cfDNA, circulating oxidized DNA; COX-2, cyclooxygenase

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Design, synthesis, and characterization of nucleosomes containing site-specific DNA damage

Keywords: ترمیم برداشت بازی; AP, apyrimidinic/apurinic; BER, base excision repair; CPD, cyclobutane pyrimidine dimer; DNase I, deoxyribonuclease I; dU, deoxyuridine; FRET, Försterresonance energy transfer; MNase, micrococcal nuclease; NER, nucleotide excision repair; NCP, nucleosome

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Pathway-centric analysis of the DNA damage response to chemotherapeutic agents in two breast cell lines

Keywords: ترمیم برداشت بازی; MMR, mismatch repair; dNTP, deoxynucleotide triphosphate; BER, base excision repair; DSB, double strand break; HR, homologous recombination; NEHJ, non-homologous end-joining; NER, nucleotide excision repair; DDR, DNA damage repair; DDS, DNA damage signall

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

DNA damage response – A double-edged sword in cancer prevention and cancer therapy

Keywords: ترمیم برداشت بازی; DDR, DNA damage response; BER, base excision repair; MMR, mismatch repair; NER, nucleotide excision repair; TLS, translesion DNA synthesis; NHEJ, nonhomologous end joining; HR, homologous recombination; SSBs, single strand DNA breaks; DSBs, double strand

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Interaction of PARP-2 with AP site containing DNA

Keywords: ترمیم برداشت بازی; DNA repair; PARP-2; AP sites; AP lyase; Schiff baseAP site, apurinic/apyrimidinic site; BER, base excision repair; PAR, poly(ADP-ribose); PARP-1, poly(ADP-ribose)polymerase-1; PARP-2, poly(ADP-ribose)polymerase-2; PARylation, poly(ADP-ribosyl)ation; Pol β

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

An altered redox balance and increased genetic instability characterize primary fibroblasts derived from xeroderma pigmentosum group A patients

Keywords: ترمیم برداشت بازی; acet, acetate; ala, alanine; ANOVA, analysis of variance; asp, asparagine; BER, base excision repair; BSO, buthionine sulphoximine; CAT, catalase; Cho, choline; CPD, cyclobutane pyrimidine dimers; CS, cockayne syndrome; CPH, 1-hydroxy-3-carboxy-2,2,5,5-te

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Multifaceted control of DNA repair pathways by the hypoxic tumor microenvironment

Keywords: ترمیم برداشت بازی; ATM, ataxia telangiectasia mutated; ATR, ataxia telangiectasia and Rad3-related; BER, base excision repair; DSB, double-strand break; H3K4me2, histone H3 lysine 4 dimethylation; H3K4me3, histone H3 lysine 4 trimethylation; H3K9me2, histone H3 lysine 9 dim

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Cross-talk between redox regulation and the ubiquitin–proteasome system in mammalian cell differentiation

Keywords: ترمیم برداشت بازی; AGE, advanced glycation end products; AP1, Activator protein-1; BER, Base excision repair; CM, Cardiomyocytes; DEG, Differential expressed gene; ERAD, Endoplasmic Reticulum-Associated Degradation; ESC, embryonic stem cells; GSH, reduced glutathione; GSSG,

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

High mobility group (HMG) proteins: Modulators of chromatin structure and DNA repair in mammalian cells

Keywords: ترمیم برداشت بازی; APE1, apurinic/apyrimidinic endonuclease 1; AP site, apurinic/apyrimidinic site; ATM, ataxia telangetasia mutated; bp, base pair; BER, base excision repair; ChIP, chromatin immunoprecipitation; cis-DDP or cisplatin, cis-diamminedichloroplatinum(II); CHUD,

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Redox regulation of genome stability by effects on gene expression, epigenetic pathways and DNA damage/repair

Keywords: ترمیم برداشت بازی; Oxidative stress; Redox signaling; Gene regulation; Epigenetics; DNA repair5-hmC, 5-hydroxymethylcytosine; 5-mC, 5-methylcytosine; AP-1, activator protein 1; Ape-1, apurinic/apyrimidinic endonuclease 1; AREs, AU-rich elements; BER, base excision repair; C

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Analysis of DNA repair gene polymorphisms in glioblastoma

Keywords: ترمیم برداشت بازی; NER, nucleotide excision repair; BER, base excision repair; DSBR, double-strand break repair; MMR, mismatch repair; ERCC1, excision repair cross-complementing rodent repair deficiency, complementation group 1; ERCC2, excision repair cross-complementing ro

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

In vivo treatment with aflatoxin B1 increases DNA oxidation, base excision repair activity and 8-oxoguanine DNA glycosylase 1 levels in mouse lung

Keywords: ترمیم برداشت بازی; AFB1, Aflatoxin B1; BER, base excision repair; 8-OHdG, 8-hydroxy-2′-deoxyguanosine; OGG1, 8-oxoguanine DNA glycosylase 1; 5-OHdU, 5-hydroxy-2′-deoxyuridine; Ug, 5,6-dihydroxy-5,6-dihydro-2′-deoxyuridineAflatoxin B1; Base excision repair; Oxidative DNA dam

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

A nonsense mutation in the Xeroderma pigmentosum complementation group F (XPF) gene is associated with gastric carcinogenesis

Keywords: ترمیم برداشت بازی; XPF, Xeroderma pigmentosum complementation group F; SNP, single nucleotide polymorphism; ERCC1, excision repair cross-complimentary group 1; NER, nucleotide excision repair; BER, base excision repair; MMR, mismatch repair; MTHFR, methylenetetrahydrofolate

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Bipyridine (2,2′-dipyridyl) potentiates Escherichia coli lethality induced by nitrogen mustard mechlorethamine

Keywords: ترمیم برداشت بازی; NER, nucleotide excision repair; BER, base excision repair; DIP, 2,2′-dipyridyl thiothiourea; HN2, bifunctional nitrogen mustard mechlorethamine; HN1, monofunctional nitrogen mustard; DCFH-DA, dihydrodichlorofluorescein diacetate; ROS, reactive oxygen spe

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Nucleotide excision repair and the 26S proteasome function together to promote trinucleotide repeat expansions

Keywords: ترمیم برداشت بازی; BER, base excision repair; GG-NER, global genome nucleotide excision repair; HD, Huntington's disease; NER, nucleotide excision repair; R4B, Rad4 binding domain; SC-Trp, synthetic complete medium lacking tryptophan; SCA1, spinocerebellar ataxia type 1; SE

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Repair of endogenous DNA base lesions modulate lifespan in mice

Keywords: ترمیم برداشت بازی; 3meA, 3-methyladenine; Aag/Mpg, alkyladenine glycosylase; AP, abasic; Atm, ataxia telangiectasia mutated; BER, base excision repair; BM, bone marrow; CR, calorie restriction; Exo1, exonuclease 1; Mgmt, O6MeG DNA methyltransferase; MMR, mismatch repair; MM

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Expression and recruitment of uracil-DNA glycosylase are regulated by E2A during antibody diversification

Keywords: ترمیم برداشت بازی; AP-2, activating protein 2; AID, activation-induced cytidine deaminase; APC, allophycocyanin; BER, base excision repair; CaM, calmodulin; CSR, class switch recombination; 6-FAM, 6-Fluorescein amidite; Id, inhibitor of differentiation; IRES, internal ribos

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Pre-steady-state fluorescence analysis of damaged DNA transfer from human DNA glycosylases to AP endonuclease APE1

Keywords: ترمیم برداشت بازی; aPu, 2-aminopurine; AP, apurinic/apyrimidinic site; BER, base excision repair; ODN, oligodeoxyribonucleotide; F, (3-hydroxytetrahydrofuran-2-yl)methyl phosphateBase excision repair; DNA glycosylase; AP endonuclease; Protein–protein interaction; Coordinati

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Redox and epigenetic regulation of the APE1 gene in the hippocampus of piglets: The effect of early life exposures

Keywords: ترمیم برداشت بازی; Oxidative stress; Epigenetics; Base excision repair; Developmental origin5mC, 5-methylcytosine; 8-oxodG, 8-oxo-7,8-dihydro-2′-deoxyguanosine; AP-1, activator protein 1; APE1, apurinic/apyrimidinic endonuclease 1; BER, base excision repair; CREB, cAMP resp

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes

Keywords: ترمیم برداشت بازی; ATM, Ataxia telangiectasia mutated; ATR, Ataxia telangiectasia-Rad3-related; BER, Base excision repair; CEES, 2-chloroethyl ethyl sulfide; DAPI, 4′,6′-diamidino-2-phenylindole; DMSO, Dimethyl sulfoxide; DSB, Double strand breaks; FACS, Fluorescence activa

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

The role of Asn-212 in the catalytic mechanism of human endonuclease APE1: Stopped-flow kinetic study of incision activity on a natural AP site and a tetrahydrofuran analogue

Keywords: ترمیم برداشت بازی; APE1, AP endonuclease1; WT, wild type; BER, base excision repair; AP, abasic site; F, 2-hydroxymethyl-3-hydroxy-tetrahydrofuran; 2-aPu, 2-aminopurine; ODN, oligodeoxyribonucleotide; MD, molecular dynamicsBase excision repair; APE1; Abasic site; Stopped-fl

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

A genetic variant in the promoter of APE1 gene (− 656 T > G) is associated with breast cancer risk and progression in a Chinese population

Keywords: ترمیم برداشت بازی; SNP, single nucleotide polymorphism; OR, odds ratio; CI, confidence interval; BER, base excision repair; APE1, AP endonuclease 1APE1; Polymorphism; Breast cancer; Susceptibility

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Mitochondrial CSA and CSB: Protein interactions and protection from ageing associated DNA mutations

Keywords: ترمیم برداشت بازی; BER, base excision repair; CS, Cockayne syndrome; DSB, double strand breaks; HR, homologous recombination; hOGG1, human 8-oxo guaninegylcosylase1; mt, mitochondria; NER, nucleotide excision repair; NHEJ, non homologous end joining; ROS, reactive oxygen sp

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه