Arginine-rich polyplexes for gene delivery to neuronal cells
Keywords: مانع خون مغزی; Gene therapy; Cell membrane; Nanocomposite; Brain cells; Blood-brain barrier;
مقالات ISI مانع خون مغزی (ترجمه نشده)
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Inhibition Against Growth of Glioblastoma Multiforme In Vitro Using Etoposide-Loaded Solid Lipid Nanoparticles with Ï-Aminophenyl-α-D-Manno-Pyranoside and Folic Acid
Keywords: مانع خون مغزی; glioblastoma multiforme; blood-brain barrier; solid lipid nanoparticle; etoposide; p-aminophenyl-a-D-manno-pyranoside; folic acid; targeted drug delivery; cancer chemotherapy; drug targeting; microemulsions;
Research ReportGlio-vascular changes during ageing in wild-type and Alzheimer׳s disease-like APP/PS1 mice
Keywords: مانع خون مغزی; Aβ; amyloid-β; AD; Alzheimer׳s disease; APP; amyloid precursor protein; BBB; blood-brain barrier; CD31; cluster of differentiation 31; GFAP; glial fibrillary acidic protein; Iba-1; ionized calcium-binding adapter molecule 1; PDGFR-β; platelet-derived
ReviewRegulation of ABC efflux transporters at blood-brain barrier in health and neurological disorders
Keywords: مانع خون مغزی; ABC efflux transporters; Blood-brain barrier; Neuroprotection; Pharmacoresistance;
Brain accumulation of the EML4-ALK inhibitor ceritinib is restricted by P-glycoprotein (P-GP/ABCB1) and breast cancer resistance protein (BCRP/ABCG2)
Keywords: مانع خون مغزی; ABC; ATP-binding cassette; ALK; anaplastic lymphoma kinase; AUC; area under the plasma concentration-time curve; BBB; blood-brain barrier; BCRP; breast cancer resistance protein; Cmax; maximum drug concentration in plasma; EML4; echinoderm microtubule-ass
Chronic systemic IL-1β exacerbates central neuroinflammation independently of the blood-brain barrier integrity
Keywords: مانع خون مغزی; (APP); β-amyloid precursor protein; (BBB); blood-brain barrier; (CSF); cerebrospinal fluid; (EAE); experimental autoimmune encephalomyelitis; (GFAP); glial fibrillary acidic protein; (iv); intravenous; (MHC II); major histocompatibility complex class II;
Effect of 3,4-Methylenedioxymethamphetamine on the Toxicokinetics and Sedative Effects of the Drug of Abuse, γ-Hydroxybutyric Acid
Keywords: مانع خون مغزی; monocarboxylate transporters; γ-hydroxybutyrate; GHB; MDMA; overdose treatment; l-lactate; membrane transport/transporters; toxicokinetics; blood-brain barrier; drug interaction;
Modulation des lipides du cerveau par l'alimentation : études chez des modèles animaux de maladies neurodégénératives
Keywords: مانع خون مغزی; Acides gras oméga 3; Alzheimer; Barrière hémato-encéphalique; Lipides; Alimentation; Omega 3 fatty acids; Alzheimer; Blood-brain barrier; Lipids; Diet;
Flavonoid metabolites transport across a human BBB model
Keywords: مانع خون مغزی; ALP; alkaline phosphatase; BBB; blood-brain barrier; CNS; central nervous system; RBE4; rat brain endothelial cell; hCMEC/D3; human brain endothelial cell; Anthocyanins; Blood-brain barrier; Flavanoids; Flavonoids metabolites; hCMEC/D3 cells; Transport;
Transporter-mediated Prostaglandin E2 Elimination across the Rat Blood-brain Barrier and Its Attenuation by the Activation of N-methyl-D-aspartate Receptors
Keywords: مانع خون مغزی; blood-brain barrier; calcium; L-glutamate; intracellular calcium ion; N-methyl-D-aspartate receptor; organic anion transporter; prostaglandin E2;
Pharmaceutical nanotechnologyPEGylated cyclodextrins as novel siRNA nanosystems: Correlations between polyethylene glycol length and nanoparticle stability
Keywords: مانع خون مغزی; ANOVA; one-way analysis of variance; AUC; area under the curve; AUMC; area under the moment curve; BBB; blood-brain barrier; CL; clearance; CNS; central nervous system; CD; cyclodextrin; DIW; deionised water; DLS; dynamic light scattering; ELS; electropho
Research ReportIncreased CD147 (EMMPRIN) expression in the rat brain following traumatic brain injury
Keywords: مانع خون مغزی; TBI; traumatic brain injury; EMMPRIN; extracellular matrix metalloproteinase inducer; MMPs; matrix metalloproteinases; BBB; blood-brain barrier; CD147; MMP-9; Immunocytochemistry; Rat; Traumatic brain injury;
Research reportThe P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram
Keywords: مانع خون مغزی; 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; serotonin; 5-HTP; 5-hydroxytryptophan; BBB; blood-brain barrier; CsA; cyclosporin A; HPLC; high performance liquid chromatography; HPLC-ECD; HPLC with electrochemical detection; MAOI; monoamine oxidase inhibitor;
Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease
Keywords: مانع خون مغزی; Aβ; amyloid-beta; AD; Alzheimer's disease; BBB; blood-brain barrier; BSA; bovine serum albumin; GSK-3β; glycogen synthase kinase-3β; GST; glutathione S-transferase; ICV; intracerebroventricularly; NFTs; neurofibrillary tangles; Nrf2; nuclear factor-E
Encéphalopathies médicamenteuses, une approche pratique pour le clinicien
Keywords: مانع خون مغزی; Encéphalopathies médicamenteuses; Encéphalopathies métaboliques; Barrière hémato-encéphalique; Ammoniaque; Drug-induced encephalopathies; Metabolic encephalopathies; Blood-brain barrier; Ammonemia;
Ghrelin inhibits BSCB disruption/hemorrhage by attenuating MMP-9 and SUR1/TrpM4 expression and activation after spinal cord injury
Keywords: مانع خون مغزی; BBB; blood-brain barrier; BSCB; blood spinal cord barrier; COX-2; cyclooxygenase-2; Ghrelin receptor; GHS-R1a; iNOS; inducible nitric oxide synthase; i.p; intraperitoneal; IL; interleukin; MMP; matrix metalloprotease; SCI; spinal cord injury; SUR1; sulfon
t-PA, but not desmoteplase, induces plasmin-dependent opening of a blood-brain barrier model under normoxic and ischaemic conditions
Keywords: مانع خون مغزی; BBB; blood-brain barrier; CNBr-fgn; cyanogen bromide-digested fibrinogen; FITC; fluorescein isothiocyanate; ICH; intracerebral haemorrhage; OGD; oxygen-glucose deprivation; LDLR; low density lipoprotein receptor; LRP-1; LDLR-related protein 1; PFA; parafo
ATP-binding cassette transporters P-glycoprotein and breast cancer related protein are reduced in capillary cerebral amyloid angiopathy
Keywords: مانع خون مغزی; Cerebral amyloid angiopathy; Alzheimer's disease; P-gp; BCRP; ABC transporters; Blood-brain barrier;
Phytoestrogens as alternative hormone replacement therapy in menopause: What is real, what is unknown
Keywords: مانع خون مغزی; Akt; protein kinase B; AMPK; 5â² AMP-activated protein kinase; BBB; blood-brain barrier; COX2; cyclooxygenase 2; E2; estradiol; EGTA; ethylene glycol tetraacetic acid; ER; estrogen receptor; ERE; Estrogen-responsive elements; ERK; Extracellular signal-re
Aquaporin-4 antibodies, CNS acidosis and neuromyelitis optica: A potential link
Keywords: مانع خون مغزی; Ab; antibodies; AQP4; aquaporin-4; BBB; blood-brain barrier; CSF; cerebrospinal fluid; CNS; central nervous system; COX; cyclooxygenase; EAE; experimental autoimmune encephalomyelitis; IgG; immunoglobulin G; NMO; neuromyelitis optica; SLE; systemic lupus
Albumin storage in neoplastic astroglial elements of gangliogliomas
Keywords: مانع خون مغزی; Epilepsy; Ganglioglioma; DNT; Focal cortical dysplasia; Albumin; Hemosiderin; Blood-brain barrier;
SPIO-conjugated, doxorubicin-loaded microbubbles for concurrent MRI and focused-ultrasound enhanced brain-tumor drug delivery
Keywords: مانع خون مغزی; Blood-brain barrier; Microbubbles; Focused ultrasound; Superparamagnetic iron oxide; Glioblastoma;
Advanced glycation end-products disrupt the blood-brain barrier by stimulating the release of transforming growth factor-β by pericytes and vascular endothelial growth factor and matrix metalloproteinase-2 by endothelial cells in vitro
Keywords: مانع خون مغزی; Diabetic encephalopathy; Advanced glycation end-products; Basement membrane hypertrophy; Blood-brain barrier;
Transporters of the blood-brain and blood-CSF interfaces in development and in the adult
Keywords: مانع خون مغزی; CSF; cerebrospinal fluid; SLC; solute-linked carriers; Blood-brain barrier; Blood-CSF barrier; Cerebrospinal fluid; Development;
IP3, a small molecule with a powerful message
Keywords: مانع خون مغزی; ANT; adenine nucleotide translocator; ATP; adenosine triphosphate; BBB; blood-brain barrier; Bcl-2; B-cell lymphoma-2; BH; Bcl-2-homology domain; BI-1; Bax-inhibitor-1; [Ca2Â +]i; cytoplasmic Ca2Â + concentration; cAMP; cyclic adenosine monophosphate; cGM
Dual-use nanoresearch of concern: Recognizing threat and safeguarding the power of nanobiomedical research advances in the wake of the H5N1 controversy
Keywords: مانع خون مغزی; Dual-use; Blood-brain barrier; Virulence; Security; Bioweapon
Neuroprotective effects of progesterone in traumatic brain injury: blunted in vivo neutrophil activation at the blood-brain barrier
Keywords: مانع خون مغزی; Intravital microscopy; Neutrophil; Endothelium; Blood-brain barrier; Traumatic brain injury; Progesterone
Poly lactic acid (PLA) nanoparticles sustain the cytotoxic action of temozolomide in C6 Glioma cells
Keywords: مانع خون مغزی; Glioblastoma; Temozolomide; C6 glioma cells; PLA nanoparticles; Blood-brain barrier
Coverage of Blood Vessels by Astrocytic Endfeet Is Reduced in Major Depressive Disorder
Keywords: مانع خون مغزی; Aquaporin-4; blood-brain barrier; cerebrovascular disease; GFAP; glia; neurovascular unit
Comparative analysis of the neurovascular injury and functional outcomes in experimental stroke models in diabetic Goto-Kakizaki rats
Keywords: مانع خون مغزی; AMP; Adenosine monophosphate; AMPK; AMP-activated protein kinase; ANOVA; Analysis of variance; BBB; Blood-brain barrier; ECA; External carotid artery; GK; Goto-Kakizaki; HT; Hemorrhagic transformation; I/R; Ischemia/reperfusion; MCAO; Middle cerebral arte
Propranolol Transport Across the Inner Blood–Retinal Barrier: Potential Involvement of a Novel Organic Cation Transporter
Keywords: مانع خون مغزی; inner blood–retinal barrier; propranolol; organic cation transporter; diabetic retinopathy; glaucoma; membrane transport; drug transport; in vitro models; TR-iBRB2 cells; blood-brain barrier
Role of nuclear receptors in the regulation of drug transporters in the brain
Keywords: مانع خون مغزی; nuclear receptors; ABC/SLC transporters; blood-brain barrier; transcription regulation
Prodrugs: A challenge for the drug development
Keywords: مانع خون مغزی; prodrugs; drugs’ metabolism; blood-brain barrier; ADEPT; GDEPT
Meningitis
Keywords: مانع خون مغزی; Aseptic; Meningismus; Blood-brain barrier; Cerebrospinal fluid; Vaccination; Prophylaxis; Acute meningitis;
Transient increase of plasma concentrations of amyloid β peptides after electroconvulsive therapy
Keywords: مانع خون مغزی; blood-brain barrier; electroconvulsive therapy; multiplexing; depression; amyloid β
Polymeric nanoparticles for drug delivery to the central nervous system
Keywords: مانع خون مغزی; Nanoparticle; Polymer; Brain; Blood-brain barrier; Convection-enhanced delivery
Melanoma Brain Metastases and Vemurafenib: Need for Further Investigation
Keywords: مانع خون مغزی; BBB; blood-brain barrier; BRAFi; BRAF inhibitor; CNS; central nervous system; FDA; Food and Drug Administration; MRI; magnetic resonance imaging; WBRT; whole-brain radiation therapy;
Acanthamoeba interactions with the blood-brain barrier under dynamic fluid flow
Keywords: مانع خون مغزی; Blood-brain barrier; Amoeba; Acanthamoeba; Mannose binding protein; Flow system;
Lipid rafts and functional caveolae regulate HIV-induced amyloid beta accumulation in brain endothelial cells
Keywords: مانع خون مغزی; AD; Alzheimer's disease; Aβ; amyloid beta; ART; antiretroviral therapy; BBB; blood-brain barrier; cav-1; caveolin-1; FTS; farnesylthiosalicylic acid; HAND; HIV-associated neurocognitive disorders; HBMEC; human brain microvascular endothelial cells; HEK
Delivery of proteins to the brain by bolaamphiphilic nano-sized vesicles
Keywords: مانع خون مغزی; Bolaamphiphiles; Vesicles; Drug delivery systems; Protein delivery; Blood-brain barrier; Brain
Prenatal Exposure to Diagnostic Ultrasound Impacts Blood-Brain Barrier Permeability in Rats
Keywords: مانع خون مغزی; Prenatal ultrasound; Blood-brain barrier; Permeability; Embryonic development; Cerebrum; Cerebellum;
Dog bites man or man bites dog? The enigma of the amino acid conjugations
Keywords: مانع خون مغزی; BA; benzoic acid; PAA; phenylacetic acid; HA; hippuric acid; GLY; glycine; GLN; glutamine; TAU; taurine; GLU; glutamic acid; EAA; excitatory amino acid; IAA; inhibitory amino acid; EAAT; excitatory amino acid transporter; ECF; extracellular fluid; CSF; ce
Glucose-responsive neurons in the subfornical organ of the rat—a novel site for direct CNS monitoring of circulating glucose
Keywords: مانع خون مغزی; blood-brain barrier; circumventricular organ; electrophysiology; glucose-sensitive neuronsaCSF, artificial cerebrospinal fluid; AP, area postrema; ARC, arcuate; CVO, circumventricular organs; GE, glucose-excited neurons; GI, glucose-inhibited neurons; NSC
Perfusion-CT assessment of blood-brain barrier permeability in patients with aneurysmal subarachnoid hemorrhage
Keywords: مانع خون مغزی; Subarachnoid hemorrhage; Vasospasm; Stroke; Perfusion-CT; Blood-brain barrier; Endothelial dysfunction
Elevated Plasma Levels of Neuropeptide Proenkephalin A Predict Mortality and Functional Outcome in Ischemic Stroke
Keywords: مانع خون مغزی; biomarker; blood-brain barrier; proenkephalin; protachykinin; strokeAUC, area under the curve; BBB, blood-brain barrier; CI, confidence interval; CT, computed tomography; HR, hazards ratio; LAA, large-artery atherosclerosis; MACCE, major adverse cerebro/c
A brain-vectored angiopep-2 based polymeric micelles for the treatment of intracranial fungal infection
Keywords: مانع خون مغزی; Blood-brain barrier; Intracranial infection; Angiopep-2; Amphotericin B; Polymeric micelles; P-gp;
Effective Gene Transfer into Central Nervous System Following Ultrasound-Microbubbles-Induced Opening of the Blood-Brain Barrier
Keywords: مانع خون مغزی; Blood-brain barrier; Central nervous system; Gene therapy; Ultrasound; Microbubbles;
Improved Anti-Tumor Effect of Liposomal Doxorubicin After Targeted Blood-Brain Barrier Disruption by MRI-Guided Focused Ultrasound in Rat Glioma
Keywords: مانع خون مغزی; Focused ultrasound; Blood-brain barrier; Doxorubicin; 9L gliosarcoma; Survival;
Val(8)GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice
Keywords: مانع خون مغزی; Blood-brain barrier; Brain; Diabetes; Insulin signaling; Neurons; Neuropeptide; Synaptic plasticity;
HIV-1 Tat-induced cerebrovascular toxicity is enhanced in mice with amyloid deposits
Keywords: مانع خون مغزی; HIV-1 infection; Amyloid; HIV-1; Aging; Blood-brain barrier; Tight junction proteins; Inflammation;