دانلود مقالات ISI درباره مانع خون مغزی + ترجمه فارسی

Early BBB breakdown and subacute inflammasome activation and pyroptosis as a result of cerebral venous thrombosis

Keywords: مانع خون مغزی; Blood-brain barrier; Cerebral venous thrombosis; MMP9; NLRP3; Neuroinflammation; Sinus thrombosis;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Antiproliferative efficacy of elderberries and elderflowers (Sambucus canadensis) on glioma and brain endothelial cells under normoxic and hypoxic conditions

Keywords: مانع خون مغزی; BBB; blood-brain barrier; Cy-3-sam-5-glu; cyanidin-3-O-sambubioside-5-O-glucoside chloride; Dp-3-rut; delphinidin 3-O-rutinoside chloride; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GLUT-1; glucose transporter-1; HBMEC; human brain microvascular end

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease

Keywords: مانع خون مغزی; AGEs; advanced glycation end-products; ARE; antioxidant-response element; AP; argpyrimidine (Nẟ-(5-hydroxy-4,6-dimethylpyrimidine-2-yl)-l-ornithine); BBB; blood-brain barrier; Casp-3; Caspase-3; CCM; Cerebral Cavernous Malformation; CNS; central nervous

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

Focusing on claudin-5: A promising candidate in the regulation of BBB to treat ischemic stroke

Keywords: مانع خون مغزی; 5α-DHP; 5α-dihydroprogestrone; ABC; ATP-binding cassette; AF6; ALL-1-fused gene from chromosome 6; ALL; acute lymphoblastic leukemia; AMPAR; amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor; Ang-1; angiopoietin-1; AP-1; activator protein-1; BBB;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

Determination of tranilast in bio-samples by LC-MS/MS: Application to a pharmacokinetic and brain tissue distribution study in rats

Keywords: مانع خون مغزی; Cmax; the maximum plasma concentration; AUC0-24; the area under the curve; BBB; blood-brain barrier; IS; internal standard; MRM; multiple reaction monitoring; CMC-Na; carboxymethyl cellulose sodium; Tranilast; Brain tissue distribution; Pharmacokinetic; L

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2018 سفارش ترجمه

Prolonged Intracisternal Papaverine Toxicity: Index Case Description and Proposed Mechanism of Action

Keywords: مانع خون مغزی; Aneurysm; Intracisternal; Oculomotor; Papaverine; Subarachnoid; Vasodilation; aSAH; Acute subarachnoid hemorrhage; BBB; Blood-brain barrier; iPPV; Intracisternal papaverine; MCA; Middle cerebral artery;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Blood-brain barrier integrity in a mouse model of Alzheimer's disease with or without acute 3D6 immunotherapy

Keywords: مانع خون مغزی; Blood-brain barrier; Alzheimer's disease; Large molecules; Cerebral amyloid angiopathy; Antibody treatment; Immunotherapy;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Is heterotopic ossification getting nervous?: The role of the peripheral nervous system in heterotopic ossification

Keywords: مانع خون مغزی; HO; heterotopic ossification; BMP; bone morphogenetic protein; BNB; blood-nerve barrier; TRPV1; transient receptor potential cation channel subfamily V member 1; sP; substance P; CGRP; Calcitonin gene-related protein; DRG; dorsal root ganglion; BBB; blood

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Neurokinin-1 receptor antagonism improves postoperative neurocognitive disorder in mice

Keywords: مانع خون مغزی; PND; Postoperative neurocognitive disorder; BBB; blood-brain barrier; NK-1R; neurokinin-1 receptor; CNS; central nervous system; SP; substance P; NK-1Ra; neurokinin-1 receptor antagonist; PBS; phosphate-buffered saline; ELISA; enzyme-linked immunosorbent

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Role of Oleanolic acid in maintaining BBB integrity by targeting p38MAPK/VEGF/Src signaling pathway in rat model of subarachnoid hemorrhage

Keywords: مانع خون مغزی; Oleanolic acid; Subarachnoid hemorrhage; Blood-brain barrier; p38 MAPK; VEGF;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Investigating the efficacy of a combination Aβ-targeted treatment in a mouse model of Alzheimer's disease

Keywords: مانع خون مغزی; Aβ; Amyloid-beta peptide; AD; Alzheimer's disease; BBB; Blood-Brain Barrier; CNS; Central nervous system; GFAP; Glial fibrillary acidic protein; MRI; Magnetic resonance image; MRIgFUS; Magnetic resonance image guided focused ultrasound; SI; scyllo-Inos

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Preparation of PEGylated liposomes incorporating lipophilic lomeguatrib derivatives for the sensitization of chemo-resistant gliomas

Keywords: مانع خون مغزی; BBB; blood-brain barrier; Br-Cn; bromoalkane; Br-C12; 1-bromododecane; Br-C14; 1-bromotetradecane; Br-C16; 1-bromohexadecane; Br-C18; 1-bromooctadecane; CHOL; cholesterol; DCM; dichloromethane; DLS; dynamic light scattering; DMEM; Dulbecco's modified Ea

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Mimicking brain tissue binding in an in vitro model of the blood-brain barrier illustrates differences between in vitro and in vivo methods for assessing the rate of brain penetration

Keywords: مانع خون مغزی; Blood-brain barrier; Endothelial cells; Brain exposure; Drug discovery; BBB permeability; Brain tissue binding; In vitro model; In-situ brain perfusion; BBB; blood-brain barrier; bBCEC; bovine brain capillary endothelial cells; EC; endothelial cells; CNS;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Assessment of HBEC-5i endothelial cell line cultivated in astrocyte conditioned medium as a human blood-brain barrier model for ABC drug transport studies

Keywords: مانع خون مغزی; Blood-Brain Barrier; ABC transporters; Efflux ratio; Human in vitro models; Astrocyte conditioned medium;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Nanosystems in nose-to-brain drug delivery: A review of non-clinical brain targeting studies

Keywords: مانع خون مغزی; Brain targeting; Drug delivery; Intranasal; In vivo; Nanosystem; Pharmacokinetics; ATCC; anatomical therapeutic chemical classification; AUC; area under the curve; BBB; blood-brain barrier; B%brain IN/IV; comparative brain bioavailability (IN vs IV); DTE%

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Platelet glycoprotein receptor Ib blockade ameliorates experimental cerebral ischemia-reperfusion injury by strengthening the blood-brain barrier function and anti-thrombo-inflammatory property

Keywords: مانع خون مغزی; Stroke; Platelet glycoprotein receptor Ib; Blood-brain barrier; Thrombo-inflammation; Macrophage-1 antigen; P-selectin;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Tacrine derivatives stimulate human glioma SF295 cell death and alter important proteins related to disease development: An old drug for new targets

Keywords: مانع خون مغزی; TMZ; temozolomide; GBM; glioblastoma multiforme; CNS; central nervous system; ROS; reactive oxygen species; BBB; blood-brain barrier; CC50; 50% cytotoxic concentration; TEM; transmission electron microscopy; SI; selectivity index; ∆ωm; mitochondrial me

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Can crosstalk between DOR and PARP reduce oxidative stress mediated neurodegeneration?

Keywords: مانع خون مغزی; Oxidative stress (OS); Delta opioid receptor (DOR); Poly (ADP-ribose)-polymerase1 (PARP1); Neuroprotection; Attenuation; OS; Oxidative stress; DOR; Delta opioid receptor; PARP; Poly (ADP-ribose)-polymerase; AD; Alzheimer's disease; PD; Parkinson's disease

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

The pathological role of NLRs and AIM2 inflammasome-mediated pyroptosis in damaged blood-brain barrier after traumatic brain injury

Keywords: مانع خون مغزی; Traumatic brain injury; Blood-brain barrier; Pyroptosis; Inflammasome; NOD-like receptors; AIM2;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Developmental and extrahepatic physiological functions of SREBP pathway genes in mice

Keywords: مانع خون مغزی; AAV; adeno-associated virus; ACC; acetyl-CoA carboxylase; AD; Alzheimer's disease; ADD1; adipocyte determination- and differentiation-dependent factor 1; APP; amyloid precursor protein; Api6; apoptosis inhibitor 6; ApoE; apolipoprotein E; ATF6; activati

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

P-glycoprotein protein expression versus functionality at the blood-brain barrier using immunohistochemistry, microdialysis and mathematical modeling

Keywords: مانع خون مغزی; P-glycoprotein; Protein expression; Functionality; Blood-brain barrier; Microdialysis; Kainate; Quinidine;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

1-Benzyl-4-methylpiperidinyl moiety in donepezil: The priority ticket across the blood-brain-barrier in rats

Keywords: مانع خون مغزی; Donepezil; Brain targeting; Active transport; Blood-brain barrier; Validation; UHPLC-MS;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Systemic L-buthionine-S-R-sulfoximine administration modulates glutathione homeostasis via NGF/TrkA and mTOR signaling in the cerebellum

Keywords: مانع خون مغزی; GSH; Cysteine transport; NGF; mTOR; Redox; Cerebellum; 4F2hc; 4F2 cell surface antigen; BBB; blood-brain barrier; BSO; L-buthionine-S-R-sulfoximine; CNS; central nervous system; DAPI; 4′,6-diamidino-2-phenylindole DTPA; diethylenetriamine penta-acetic a

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

pH-sensitive folic acid and dNP2 peptide dual-modified liposome for enhanced targeted chemotherapy of glioma

Keywords: مانع خون مغزی; Blood-brain barrier; Glioma; Cell penetrating peptide; Folic acid; pH sensitive;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Niosomes decorated with dual ligands targeting brain endothelial transporters increase cargo penetration across the blood-brain barrier

Keywords: مانع خون مغزی; Blood-brain barrier; Brain endothelial cell; Drug targeting; Dual-ligand; Nanoparticle; Niosome; Solute carriers;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

An integrated computational hierarchy for identification of potent inhibitors against Shikimate Kinase enzyme from Shigella sonnei, a major cause of global dysentery

Keywords: مانع خون مغزی; ATP; adenosine triphosphate; SK; Shikimate Kinase; PDB; Protein Data Bank; GOLD; Genetic Optimization for Ligand Docking; VMD; Visual Molecular Dynamics; DS; Discovery Studio; PRDOS; Protein DisOrder prediction System; PK; pharmacokinetics; BBB; blood-bra

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Dithiolethione ACDT suppresses neuroinflammation and ameliorates disease severity in experimental autoimmune encephalomyelitis

Keywords: مانع خون مغزی; MS/EAE; Microglia; Th1/Th17; A1 astrocyte; ACDT; Neuroinflammation; Blood-brain barrier;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Notch signaling is impaired during inflammation in a Lunatic Fringe-dependent manner

Keywords: مانع خون مغزی; AJ; adherence junction; APC; Allophycocyanin; BBB; blood-brain barrier; BECs; brain endothelial cells; CNS; central nervous system; DAPT; N-[N-(3,5-Difluorophenacetyl)-l-alanyl]-S-phenylglycine t-butyl ester; DLL1, -3 and -4; Delta-like family ligand 1, -

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

P-glycoprotein and breast cancer resistance protein restrict brigatinib brain accumulation and toxicity, and, alongside CYP3A, limit its oral availability

Keywords: مانع خون مغزی; ABC; ATP-binding cassette; ALK; anaplastic lymphoma kinase; ANOVA; analysis of variance; AUC; area under plasma concentration-time curve; BBB; blood-brain barrier; BCRP; breast cancer resistance protein; BTB; blood-testis barrier; Cbrain; brain concentrat

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Salidroside improves brain ischemic injury by activating PI3K/Akt pathway and reduces complications induced by delayed tPA treatment

Keywords: مانع خون مغزی; Salidroside; Cerebral ischemia; Blood-brain barrier; tPA;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Scaffold-based novel SHP2 allosteric inhibitors design using Receptor-Ligand pharmacophore model, virtual screening and molecular dynamics

Keywords: مانع خون مغزی; SPB; structure based pharmacophore; ADMET; absorption, distribution, metabolism, excretion, and toxicity; TCPTP; T cell protein-tyrosinephosphatase; PTP1B; protein tyrosine phosphatase 1B; NS; Noonan Syndrome; JMML; juvenile myelomonocytic leukemia; AML;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Adenoviral vector-induced silencing of RGMa attenuates blood-brain barrier dysfunction in a rat model of MCAO/reperfusion

Keywords: مانع خون مغزی; Repulsive guidance molecule A; Blood-brain barrier; Ischemia-reperfusion injury; Middle cerebral artery occlusion;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

[D-Leu-4]-OB3 and MA-[D-Leu-4]-OB3, small molecule synthetic peptide leptin mimetics, improve glycemic control in diet-induced obese (DIO) mice

Keywords: مانع خون مغزی; AD; Alzheimer's Disease; AUC; area under the curve; BBB; blood-brain barrier; BMI; body mass index; CNS; central nervous system; DDM; dodecyl maltoside; DIO; diet-induced obese; HF; high-fat; LF; low-fat; OGTT; oral glucose tolerance test; PBS; phosphat

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Hydroxysafflor yellow a protects brain microvascular endothelial cells against oxygen glucose deprivation/reoxygenation injury: Involvement of inhibiting autophagy via class I PI3K/Akt/mTOR signaling pathway

Keywords: مانع خون مغزی; 3-MA; 3-methyladenine; A; absorbance; BBB; blood-brain barrier; BCA; bicinchoninic acid; BMECs; brain microvascular endothelial cells; BSA; bovine serum albumin; CNS; central nervous system; DMSO; dimethylsulfoxide; ECL; enhanced chemiluminescence; FBS; f

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

In vivo assessment of the human cerebral microcirculation and its glycocalyx: A technical report

Keywords: مانع خون مغزی; Glycocalyx; Microcirculation; Blood-brain barrier; Cerebrovascular disease; Epilepsy;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

FTY720 attenuates behavioral deficits in a murine model of systemic lupus erythematosus

Keywords: مانع خون مغزی; Neuropsychiatric lupus; FTY720; Blood-brain barrier; Neuron death; PI3K/AKT;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Potential role of α-lipoic acid and Ginkgo biloba against silver nanoparticles-induced neuronal apoptosis and blood-brain barrier impairments in rats

Keywords: مانع خون مغزی; Silver nanoparticles; α-Lipoic acid; Ginkgo biloba L.; Neurotoxicity; Blood-brain barrier; Tight junctions; Apoptosis; Oxidative stress; Neuroprotection;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Cell cultures in drug discovery and development: The need of reliable in vitro-in vivo extrapolation for pharmacodynamics and pharmacokinetics assessment

Keywords: مانع خون مغزی; 3Rs; Reduction, Replacement, Refinement; PBPK; physiologically based pharmacokinetic; 2D; two-dimensional; 3D; three-dimensional; HTS; high-throughput screening; IVIVE; in vitro-in vivo extrapolation; ADME; absorption, distribution, metabolism and excreti

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Influence of breast cancer resistance protein and P-glycoprotein on tissue distribution and excretion of Ko143 assessed with PET imaging in mice

Keywords: مانع خون مغزی; PET; [11C]Ko143; Breast cancer resistance protein; P-glycoprotein; Blood-brain barrier; Pharmacokinetic disposition; Pharmaceutical excipients;

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Prediction of human CNS pharmacokinetics using a physiologically-based pharmacokinetic modeling approach

Keywords: مانع خون مغزی; Physiology-based pharmacokinetics (PBPK); Blood-brain barrier; Translational modeling; Disease effects; CNS; Active transport;

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Modulating membrane fluidity corrects Batten disease phenotypes in vitro and in vivo

Keywords: مانع خون مغزی; Neuronal ceroid lipofuscinoses; JNCL; CLN3; Cav-1; Cdc42; Blood-brain barrier; Carbenoxolone; Membrane fluidity;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Microfluidics contribution to pharmaceutical sciences: From drug discovery to post marketing product management

Keywords: مانع خون مغزی; ALS; amyotrophic lateral sclerosis; BBB; blood-brain barrier; CE; capillary electrophoresis; CL; chemiluminescence; CMC; capillary microsampling; CSF; cerebrospinal fluid; CTC; circulating cancer cells; CYP; cytochrome P; DBS; dried blood spots; DDS; drug

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Functionalized liposomes and phytosomes loading Annona muricata L. aqueous extract: Potential nanoshuttles for brain-delivery of phenolic compounds

Keywords: مانع خون مغزی; Annona muricata L.; Phytosomes; Liposomes; mApoE; hMAO-A; Hydrogen peroxide scavenging; AE; aqueous extract; ApoE; apolipoprotein E; BBB; blood-brain barrier; CNS; central nervous system; DCM; dichloromethane; DMSO; dimethylsulfoxide; DSPE-PEG-maleimide;

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Linking the biological underpinnings of depression: Role of mitochondria interactions with melatonin, inflammation, sirtuins, tryptophan catabolites, DNA repair and oxidative and nitrosative stress, with consequences for classification and cognition

Keywords: مانع خون مغزی; Major depressive disorder; Oxidative and nitrosative stress; Kynurenine; Aryl hydrocarbon; Immune-inflammation; Mitochondria; Pathophysiology; Melatonin; Treatment; Classification; Cognition; 3-OH-ANA; 3-hydroxyanthranillic acid; 3-OH-Kyn; 3-hydroxykynure

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

The angiotensin II type I receptor antagonist losartan retards amygdala kindling-induced epileptogenesis

Keywords: مانع خون مغزی; ADT; afterdischarge threshold; ANOVA; analysis of variance; AT1; angiotensin II type 1 receptor; BBB; blood-brain barrier; EEG; electroencephalography; ECM; extracellular matrix; GABA; gamma-aminobutyric acid; i.c.v.; intracerebroventricular; i.p.; intrap

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Iron-loaded transferrin (Tf) is detrimental whereas iron-free Tf confers protection against brain ischemia by modifying blood Tf saturation and subsequent neuronal damage

Keywords: مانع خون مغزی; ADC; apparent diffusion coefficient; ATf; apotransferrin; B-27; a medium supplement to grow neurons; BBB; blood-brain barrier; CM; conditioned medium; CM-H2DCFDA; 5-chloromethyl-2,7-dichlorodihydrofluorescein diacetate; DAPK-1; anti-death-associated prote

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2018 سفارش ترجمه

Targeted inhibition of RAGE reduces amyloid-β influx across the blood-brain barrier and improves cognitive deficits in db/db mice

Keywords: مانع خون مغزی; Type 2 diabetes mellitus; Blood-brain barrier; Receptor for advanced glycation end products; Amyloid-β; Cognitive deficits;

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2018 سفارش ترجمه

High brain distribution of a new central nervous system drug candidate despite its P-glycoprotein-mediated efflux at the mouse blood-brain barrier

Keywords: مانع خون مغزی; Blood-brain barrier; Brain distribution; P-gp efflux; Pharmacokinetics; In situ brain perfusion;

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

Impact of developmental exposure to methylphenidate on rat brain's immune privilege and behavior: Control versus ADHD model

Keywords: مانع خون مغزی; ADHD; Anxiety-like behavior; Astrocytes; Blood-brain barrier; Methylphenidate; Microglia; Neuroinflammation; Leukocytes; Oxidative stress; Vesicular transport;

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

Role of efflux transporters in the absorption, distribution and elimination in rodents of a novel PDE4 inhibitor, CHF6001

Keywords: مانع خون مغزی; ADME; absorption, distribution, metabolism and excretion; AUC0-t(last); area under the concentration-time curve up to the last measurable concentration; AUCinf; area under the concentration-time curve up to infinity; AUCτ; area under the concentration-ti

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2018 سفارش ترجمه