
Salt bridges in prion proteins are necessary for high-affinity binding to the monoclonal antibody T2
Keywords: BSE; bovine spongiform encephalopathy; CD; circular dichroism; ka; association rate constant; kd; dissociation rate constant; KD; dissociation constant; PAGE; polyacrylamide gel electrophoresis; PrP; prion protein; PrPC; cellular prion protein; PrPSc; abn