Membrane trafficking of aquaporin 3 induced by epinephrine
Keywords: سلول های Caco-2; Aquaporin 3 (AQP3); Epinephrine; Trafficking; Protein kinase C (PKC); Glycerol; Caco-2 cells;
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Transport characteristics of ginkgolide B by Caco-2 cells and examination of ginkgolide B oral absorption potential using rat in situ intestinal loop method
Keywords: سلول های Caco-2; Ginkgolide B; Intestinal absorption; Caco-2 cells; In situ closed intestinal loop
Uptake of 4-chloro-2-methylphenoxyacetic acid (MCPA) from the apical membrane of Caco-2 cells by the monocarboxylic acid transporter
Keywords: سلول های Caco-2; 4-Chloro-2-methylphenoxyacetic acid (MCPA); Monocarboxylic acid transporter (MCT); Caco-2 cells; Benzoic acid
Confocal microscopic analysis of transport mechanisms of insulin across the cell monolayer
Keywords: سلول های Caco-2; Hydrogels; Caco-2 cells; Confocal microscopy; Insulin; Transport
Quantum dots for tracking cellular transport of lectin-functionalized nanoparticles
Keywords: سلول های Caco-2; Quantum dots; Fluorescent probe; Nanoparticles; Transport; Caco-2 cells
De-phosphorylation of GR at Ser203 in nuclei associates with GR nuclear translocation and GLUT5 gene expression in Caco-2 cells
Keywords: سلول های Caco-2; Caco-2 cells; De-phosphorylation; Glucocorticoid hormone receptor; GLUT5; Nuclear translocation; p44/42 MAPK
Cellular transport of lutein is greater from uncooked rather than cooked spinach irrespective of whether it is fresh, frozen, or canned
Keywords: سلول های Caco-2; HBSS, hanks balanced salt solution; HPLC, high-performance liquid chromatographyBioavailability; Carotenoid; Caco-2 cells; Digestion; In vitro; Lutein; Micelles; Spinach (Spinacia oleracea)
Kefiran antagonizes cytopathic effects of Bacillus cereus extracellular factors
Keywords: سلول های Caco-2; Kefiran; Bacterial exopolysaccharides; Bacillus cereus; Caco-2 cells; Virulence; Protein toxins
Transport of valproate at intestinal epithelial (Caco-2) and brain endothelial (RBE4) cells: Mechanism and substrate specificity
Keywords: سلول های Caco-2; Caco-2 cells; Drug delivery; Membrane transport; RBE4 cells; Valproate; Valproic acid
Effects of dietary factors on iron uptake from ferritin by Caco-2 cells
Keywords: سلول های Caco-2; Ferritin; Iron; Iron bioavailability; Caco-2 cells; Biofortification
Supplemental inulin does not enhance iron bioavailability to Caco-2 cells from milk- or soy-based, probiotic-containing, yogurts but incubation at 37 °C does
Keywords: سلول های Caco-2; Prebiotic; Inulin; Yogurts; Iron bioavailability; Caco-2 cells
Chicken thigh, chicken liver, and iron-fortified wheat flour increase iron uptake in an in vitro digestion/Caco-2 cell model
Keywords: سلول های Caco-2; Iron uptake; Meat; Iron-fortified food; In vitro digestion; Caco-2 cells; Bioavailability
Thiolated chitosans: Development and in vitro evaluation of an oral tobramycin sulphate delivery system
Keywords: سلول های Caco-2; Tobramycin sulphate; Permeation enhancement; Caco-2 cells; Ussing-type chambers; Chitosan-NAC
Growth surface-induced gene and protein expression patterns in Caco-2 cells
Keywords: سلول های Caco-2; Caco-2 cells; Differentiation; Gene expression; Protein expression; Influence of growth supports
Bioavailability of the antihypertensive peptide LHLPLP: Transepithelial flux of HLPLP
Keywords: سلول های Caco-2; Antihypertensive; Peptide; Absorption; Caco-2 cells; Bioavailability.
Processing plant persistent strains of Listeria monocytogenes appear to have a lower virulence potential than clinical strains in selected virulence models
Keywords: سلول های Caco-2; Listeria monocytogenes; Caco-2 cells; Drosophila melanogaster; Caenorhabditis elegans; Guinea pig; Persistence
Influence of anthocyanins and derivative pigments from blueberry (Vaccinium myrtillus) extracts on MPP+ intestinal uptake: A structure–activity approach
Keywords: سلول های Caco-2; Absorption; Anthocyanin; Bioavailability; Caco-2 cells; Diet; Intestinal epithelia; MPP+; Organic cation
Estimation of hydroxymethylfurfural availability in breakfast cereals. Studies in Caco-2 cells
Keywords: سلول های Caco-2; Hydroxymethylfurfural; Breakfast cereals; In vitro digestion; Caco-2 cells; Availability
Uptake of 3,4-methylenedioxymethamphetamine and its related compounds by a proton-coupled transport system in Caco-2 cells
Keywords: سلول های Caco-2; MDMA; Amphetamine-type stimulant; Transport; Caco-2 cells; Intestinal absorption
Mechanisms and kinetics of citrulline uptake in a model of human intestinal epithelial cells
Keywords: سلول های Caco-2; Citrulline; Caco-2 cells; Amino acid transporter; Transport kinetic
Permeation enhancer effect of chitosan and chitosan derivatives: Comparison of formulations as soluble polymers and nanoparticulate systems on insulin absorption in Caco-2 cells
Keywords: سلول های Caco-2; Caco-2 cells; Insulin nanoparticles; Trimethyl chitosan; Dimethylethyl chitosan; Diethylmethyl chitosan; Triethyl chitosan; Uptake; Transcellular transport; Paracellular transport; Mass balance studies
Permeability of surface-modified polyamidoamine (PAMAM) dendrimers across Caco-2 cell monolayers
Keywords: سلول های Caco-2; PAMAM dendrimers; Polyamines; transepithelial electrical resistance (TEER); Caco-2 cells; Transepithelial transport; methylthiazoletetrazolium (MTT) assay
Effect of N-betainate and N-piperazine derivatives of chitosan on the paracellular transport of mannitol in Caco-2 cells
Keywords: سلول های Caco-2; Absorption enhancer; Caco-2 cells; Chitosan; Cytotoxicity; Permeation; Paracellular transport
Iron-related transcriptomic variations in Caco-2 cells: In silico perspectives
Keywords: سلول های Caco-2; Iron; Hemin; Caco-2 cells; Microarray analysis of gene expression; Functional annotation; Text-mining;
Cytotoxicity of oxidised lipids in cultured colonal human intestinal cancer cells (caco-2 cells)
Keywords: سلول های Caco-2; Frozen fish; Lipid peroxidation; Antioxidant; Caco-2 cells; Apoptosis
Passive oral drug absorption can be predicted more reliably by experimental than computational models—Fact or myth
Keywords: سلول های Caco-2; Intestinal absorption; Pharmacokinetics; Oral administration; Caco-2 cells; Cell line; Computer simulation; QSPR modelling; PAMPA
Small P-gp modulating molecules: SAR studies on tetrahydroisoquinoline derivatives
Keywords: سلول های Caco-2; P-Glycoprotein; P-gp inhibitors; Tetrahydroisoquinoline derivatives; Caco-2 cells; Vinblastine transport; MCF-7/Adr cells
Viability and permeability across Caco-2 cells of CBZ solubilized in fully dilutable microemulsions
Keywords: سلول های Caco-2; Microemulsions; Carbamazepine; Caco-2 cells; Solubilization; Non-ionic surfactants
A Comparison of the Effect of Chitosan and Chitosan-Coated Vesicles on Monolayer Integrity and Permeability Across Caco-2 and 16HBE14o-Cells
Keywords: سلول های Caco-2; chitosan; chitosan-coated vesicles; 16HBE14o-cells; Caco-2 cells; permeability enhancement; toxicity;
Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories
Keywords: سلول های Caco-2; Caco-2 cells; Active transport; ABC-transport; SLC-transport; Drug transport protein expression; Drug transport protein function
Increased Paracellular Absorption by Bile Salts and P-Glycoprotein Stimulated Efflux of Otilonium Bromide in Caco-2 Cells Monolayers as a Model of Intestinal Barrier
Keywords: سلول های Caco-2; otilonium bromide; Caco-2 cells; bile salts; intestinal absorption; permeability; P-glycoprotein; paracellular transport; ABC, ATP-binding cassette protein; CMC, critical micelle concentration; EDTA, disodium ethylenediaminetetra-acetate; EGTA, ethylene-g
Simulation Modelling of Human Intestinal Absorption using Caco-2 Permeability and Kinetic Solubility Data for Early Drug Discovery
Keywords: سلول های Caco-2; mathematical model; Caco-2 cells; gastrointestinal transit; in silico modeling; in vitro/in vivo correlations (IVIVC); intestinal absorption; pharmacokinetics; physiological model; solubility; nonlinear pharmacokinetics;
Caco-2 cell permeability and stability of two d-glucopyranuronamide conjugates of thyrotropin-releasing hormone
Keywords: سلول های Caco-2; TRH; Caco-2 cells; Drug delivery; Lipoamino acids; Sugar conjugation
Cobalamin-mediated regulation of transcobalamin receptor levels in rat organs
Keywords: سلول های Caco-2; Caco-2 cells; Cobalamin; Cobalamin deficiency; Spinal cord; Transcobalamin receptor; Tumor necrosis factor
Interactions between 3,4-methylenedioxymethamphetamine, methamphetamine, ketamine, and caffeine in human intestinal Caco-2 cells and in oral administration to rats
Keywords: سلول های Caco-2; MDMA; Methamphetamine; Ketamine; Caffeine; Amphetamine-type stimulant; Caco-2 cells; Rats; Intestinal absorption
Accumulation of transferrin in Caco-2 cells: A possible mechanism of intestinal transferrin absorption
Keywords: سلول های Caco-2; Transferrin; Transferrin receptor; Caco-2 cells; Accumulation; Oral absorption
Capsaicin induces cofilin dephosphorylation in human intestinal cells: The triggering role of cofilin in tight-junction signaling
Keywords: سلول های Caco-2; Capsaicin; Caco-2 cells; Tight-junction permeability; Cofilin dephosphorylation; Ca2+ influx; Actin reorganization
Assessment of coenzyme Q10 absorption using an in vitro digestion-Caco-2 cell model
Keywords: سلول های Caco-2; Coenzyme Q10; Ubiquinone; Caco-2 cells; Intestinal absorption; In vitro models; Bioavailability
Functional characterization of peptide transporters in MDCKII–MDR1 cell line as a model for oral absorption studies
Keywords: سلول های Caco-2; Madin–Darby canine kidney cells; MDCKII–MDR1; MDCKII–WT; Caco-2 cells; Peptide transporter; P-glycoprotein (P-gp); Gly-Sar; Apical (AP); Basolateral (BL); Uptake; Transport; Permeability
Ferritin synthesis by Caco-2 cells as an indicator of iron bioavailability: Application to milk-based infant formulas
Keywords: سلول های Caco-2; Ferritin; Caco-2 cells; Iron bioavailability; In vitro digestion; Infant formulas
Automated measurement of permeation and dissolution of propranolol HCl tablets using sequential injection analysis
Keywords: سلول های Caco-2; Dissolution; Permeation; Absorption; Caco-2 cells; Sequential injection analysis (SIA)
Effect of long-term fluoxetine treatment on the human serotonin transporter in Caco-2 cells
Keywords: سلول های Caco-2; Human serotonin transporter; Fluoxetine; Caco-2 cells
In vitro evaluation of dendrimer prodrugs for oral drug delivery
Keywords: سلول های Caco-2; PAMAM dendrimers; Enzymatic stability; Transepithelial transport; Caco-2 cells; Prodrugs
Nanosized insulin-complexes based on biodegradable amine-modified graft polyesters poly[vinyl-3-(diethylamino)-propylcarbamate-co-(vinyl acetate)-co-(vinyl alcohol)]-graft-poly(l-lactic acid): Protection against enzymatic degradation, interaction with Cac
Keywords: سلول های Caco-2; Insulin; Nanocomplexes; Protein delivery; Enzymatic degradation; Caco-2 cells; Cytotoxicity;
Availability of iron from milk-based formulas and fruit juices containing milk and cereals estimated by in vitro methods (solubility, dialysability) and uptake and transport by Caco-2 cells
Keywords: سلول های Caco-2; Iron bioavailability; Infant foods; Simulated digestion; Caco-2 cells
P-glycoprotein and cytochrome P450 3A4 involvement in risperidone transport using an in vitro Caco-2/TC7 model and an in vivo model
Keywords: سلول های Caco-2; ab; apical to basolateral; AQ; absorptive quotient; AUCT; area under the curve; ba; basolateral to apical; ClR; renal clearance; Cmax; maximum plasma concentration; CYP; cytochrome P450; ER; efflux ratio; F; fraction not metabolised; FA; fraction absorbed
Physiological levels of tea catechins increase cellular lipid antioxidant activity of vitamin C and vitamin E in human intestinal Caco-2 cells
Keywords: سلول های Caco-2; (â)-Epigallocatechin-3-gallate; Vitamin C; Vitamin E; Malondialdehyde; Caco-2 cells;
Flavonoids from a grape seed extract interact with digestive secretions and intestinal cells as assessed in an in vitro digestion/Caco-2 cell culture model
Keywords: سلول های Caco-2; Procyanidin-rich grape seed extract; Caco-2 cells; In vitro digestion; Proteins interactions
Intestinal transport and metabolism of acrylamide
Keywords: سلول های Caco-2; Acrylamide; Caco-2 cells; Intestinal transport; Glutathione; CYP2E1
Permeability assessment for solid oral drug formulations based on Caco-2 monolayer in combination with a flow through dissolution cell
Keywords: سلول های Caco-2; Oral absorption; Caco-2 cells; Dissolution; Permeation; Propranolol HCl; Biopharmaceutical classification system (BCS)