Accumulation of carboxy-terminal fragments of APP increases phosphodiesterase 8B
Keywords: cAMP; Alzheimer's disease; Amyloid; APP; CTF; Aβ; Phosphodiesterase; cAMP; Proteomics;
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Effect of LIF-withdrawal on acetylcholine synthesis in the embryonic stem cell line CGR8 is not mediated by STAT3, PI3Ks or cAMP/PKA pathways
Keywords: cAMP; ACh; acetylcholine; HPLC; high pressure liquid chromatography; DMSO; dimethylsulfoxide; FCS; fetal calf serum; FLLL31; (E,E)-1,7-Bis(3,4-dimethoxy-phenyl)-4,4-dimethyl-1,6-heptadiene-3,5-dione; H89; N-[2-(p-Bromocin-amino) ethyl]-5-isoquinolinesulfonamide
Prostacyclin receptor expression on platelets of humans with type 2 diabetes is inversely correlated with hemoglobin A1c levels
Keywords: cAMP; Prostacyclin receptor; Platelet; cAMP; Type 2 diabetes; Radioligand binding; Western blot
Lannea coromandelica attenuates glucagon and oxyntomodulin mediated cAMP formation in HEK cells stably-expressing human glucagon receptor
Keywords: cAMP; Lannea coromandelica; Glucagon; Oxyntomodulin; cAMP; Mechanism; Diabetes;
Decrease of phosphorylated CREB and ERK in nucleus accumbens is associated with the incubation of heroin seeking induced by cues after withdrawal
Keywords: cAMP; CREB; cAMP response element binding protein; ERK; extracellular regulated protein kinases; PDE4; phosphodiesterase-4; aCSF; arificial cerebrospinal fluid; Addiction; cAMP; Opioid; Phosphodiesterase-4; Transcription factor;
Change in expression of vesicular protein synapsin II by chronic treatment with D2 allosteric modulator PAOPA
Keywords: cAMP; cAMP; cyclic adenosine monophosphate; D2R; dopamine D2 receptor; ECL; enhanced chemiluminescence; ERK 1/2; extracellular signal-regulated kinase 1/2; GABA; γ-amino butyric-acid; GAPDH; glyceraldehydes-3-phosphate dehydrogenase; HRP; horseradish peroxidas
Prostaglandin D2 regulates human colonic ion transport via the DP1 receptor
Keywords: cAMP; Intestine; Ion transport; Inflammation; Prostaglandin D2; cAMP; Colonic; Epithelium
Phosphodiesterase 3 (PDE3) inhibition with cilostazol does not block in vivo oocyte maturation in rhesus macaques (Macaca mulatta)
Keywords: cAMP; Nonhormonal contraception; cAMP; Germinal vesicle; Nonhuman primate; Meiosis
Disruption of β-catenin binding to parathyroid hormone (PTH) receptor inhibits PTH-stimulated ERK1/2 activation
Keywords: cAMP; PTH1R; β-catenin; G protein; ERK1/2; cAMP; Intracellular calcium;
Oxidative stress induces the biosynthesis of citrinin by Penicillium verrucosum at the expense of ochratoxin
Keywords: cAMP; Penicillium verrucosum; Ochratoxin; Citrinin; cAMP; Oxidative stress; Adaptation;
Resveratrol-induced SIRT1 activation promotes neuronal differentiation of human bone marrow mesenchymal stem cells
Keywords: cAMP; Resveratrol; Bone marrow mesenchymal stem cells (BM-MSCs); Neuronal differentiation; Sirtuin1 (SIRT1); AMPK; AMP-activated protein kinase; BHA; butylated hydroxyanisole; BM-MSCs; bone marrow-mesenchymal stem cells; cAMP; cyclic AMP; ctrl-MSCs; control-MSC
Short CommunicationLong-term cognitive dysfunction in the rat following docetaxel treatment is ameliorated by the phosphodiesterase-4 inhibitor, rolipram
Keywords: cAMP; Chemobrain; Mood; Docetaxel; Chemotherapy; Cognition; cAMP;
FCRL3 gene polymorphisms confer risk for sudden sensorineural hearing loss in a Chinese Han Population
Keywords: cAMP; A; adenosine; A; absorbance (1Â cm); aa; amino acid(s); Ab; antibody(ies); Ad; adenovirus; AdoMet (or SAM); S-adenosylmethionine; AMV; avian myeloblastosis virus; Ap; ampicillin; PGal; P-galactosidase; bp; base pair(s); BSA; bovine serum albumin; C; cytid
Crystal structure of cyclic nucleotide-binding-like protein from Brucella abortus
Keywords: cAMP; Brucella abortus; Cyclic nucleotide binding (CNB) domain; Crystal structure; cAMP; 3â²,5â²-cyclic adenosine monophosphate; cGMP; 3â²,5â²-cyclic guanosine monophosphate; cNMP; cyclic nucleotide monophosphate; CNB; cyclic nucleotide binding; PBC; phosph
Selective enhancement of wnt4 expression by cyclic AMP-associated cooperation between rat central astrocytes and microglia
Keywords: cAMP; Wnt4; cAMP; Astrocyte; Microglia;
Tasimelteon: A selective and unique receptor binding profile
Keywords: cAMP; Tasimelteon; Hetlioz®; Circadian rhythm; Circadian regulator; Non-24; Melatonin receptor; AMP; Adenosine monophosphate; BSA; Bovine serum albumin; cAMP; Cyclic AMP; DMRA; Dual Melatonin Receptor Agonist; EC50; 50% of the maximal effect; EDTA; Ethylenedia
Metformin reduces the endotoxin-induced down-regulation of apolipoprotein E gene expression in macrophages
Keywords: cAMP; Metformin; Apolipoprotein E; NF-κB; Macrophages; Multienhancer; LPS; AMPK; adenosine-monophosphate-activated protein kinase; apoE; apolipoprotein E; cAMP; cyclic adenosine monophosphate; CD36; cluster of differentiation 36; Cox2; cyclooxygenase 2; DMEM;
Complex formation and functional interaction between adenosine A1 receptor and type-1 metabotropic glutamate receptor
Keywords: cAMP; Adenosine receptor; Metabotropic glutamate receptor; FRET; GPCR; cAMP
Modulation of estradiol synthesis and aromatase activity in human choriocarcinoma JEG-3 cells exposed to tetrabromobisphenol A
Keywords: cAMP; JEG-3; Tetrabromobisphenol A; Estradiol; Aromatase; cAMP; Cytotoxicity;
The mixed-action delta/mu opioid agonist MMP-2200 does not produce conditioned place preference but does maintain drug self-administration in rats, and induces in vitro markers of tolerance and dependence
Keywords: cAMP; Drug self-administration; Conditioned place preference; Delta opioid receptor (DOR); Barrestin2; cAMP; rats
OxeR1 regulates angiotensin II and cAMP-stimulated steroid production in human H295R adrenocortical cells
Keywords: cAMP; Oxoeicosanoid receptor OxeR1; Steroidogenesis; StAR protein; cAMP; Angiotensin II; ERK1/2
Coumestrol inhibits carotid sinus baroreceptor activity by cAMP/PKA dependent nitric oxide release in anesthetized male rats
Keywords: cAMP; Coumestrol; Carotid baroreceptor activity; eNOS; cAMP; PKACumoestrol (PubChem CID: 5281707); Nitric oxide (PubChem CID: 145068); l-NAME (PubChem CID: 39836); SIN-1 (PubChem CID: 9859122); LY294002 (PubChem CID: 3973); PD98059(PubChem CID: 4713)
PACAP and VIP signaling in chondrogenesis and osteogenesis
Keywords: cAMP; ALP; alkaline phosphatase; BMP; bone morphogenetic protein; cAMP; cyclic adenosine monophosphate; CREB; cAMP response element-binding protein; ECM; extracellular matrix; HH; Hedgehog; IHH; Indian Hedgehog; MAPK; mitogen-activated protein kinase; NFAT; nuc
Vascular Dilation, Tachycardia, and Increased Inotropy Occur Sequentially with Increasing Epinephrine Dose Rate, Plasma and Myocardial Concentrations, and cAMP
Keywords: cAMP; Epinephrine; cAMP; Myocardial tissue; Heart rate; Vascular tone; Contractility;
Diadenosine tetraphosphate improves adrenergic anti-glaucomatous drug delivery and efficiency
Keywords: cAMP; Brimonidine; Corneal epithelium; Diadenosine tetraphosphate; Drug delivery; Glaucoma; Intraocular pressure; Tight junction; Timolol; Ap4A; P1,P4-Di (adenosine-5â²) tetraphosphate; cAMP; Adenosine 3â²,5â²-cyclic monophosphate; CA; carbonic anhydrase; GA
Arylpiperazine agonists of the serotonin 5-HT1A receptor preferentially activate cAMP signaling versus recruitment of β-arrestin-2
Keywords: cAMP; 5-HT; 5-hydroxytryptamine; cAMP; 3â²,5â²-cyclic adenosine monophosphate; ERK1/2; extracellular signal-regulated kinases 1/2; GPCR; G protein-coupled receptor; LogEC50; logarithm of agonist concentration that induces half-maximal response; Emax; maximal
Design, synthesis, pharmacological characterization of a fluorescent agonist of the P2Y14 receptor
Keywords: cAMP; DXQJLXWZLNCEJX-VBCGWZPHSA-N; BODIPY; boron-dipyrromethene; cAMP; 3â²,5â²-cyclic adenosine monophosphate; CHO; Chinese hamster ovary; COMU; [[(Z)-(1-cyano-2-ethoxy-2-oxoethylidene)amino]oxy-morpholin-4-ylmethylidene]-dimethylazanium hexafluorophosphate;
Translating Basic Research Into Clinical PracticeProstanoids in Asthma and COPD: Actions, Dysregulation, and Therapeutic Opportunities
Keywords: cAMP; cAMP; cyclic adenosine monophosphate; COX; cyclooxygenase; EP; E prostanoid receptor; Epac; exchange protein activated by cyclic adenosine monophosphate; GPCR; G protein-coupled receptor; IP; I prostanoid receptor; PG; prostaglandin; PKA; protein kinase A
Prolactin and the dietary protein/carbohydrate ratio regulate the expression of SNAT2 amino acid transporter in the mammary gland during lactation
Keywords: cAMP; BSA; bovine serum albumin; cAMP; cyclic adenosine monophosphate; CRE; cAMP response element; DAB; diaminobenzidine; ECL; enhanced chemiluminescence; HPRT1; hypoxanthine phosphoribosyl transferase 1; HPR; horseradish peroxidase; JaK2; janus kinase 2; MAPK;
Dissecting high from low responders in a vitamin D3 intervention study
Keywords: cAMP; 1,25(OH)2D3; 1α,25-dihydroxyvitamin D3; 25(OH)D3; 25-dihydroxyvitamin D3; ADIPOQ; adiponectin; ASAP2; ArfGAP with SH3 domain, ankyrin repeat and PH domain 2; B2M; beta-2-microglobulin; CAMP; cathelicidin antimicrobial peptide; CD14; CD14 molecule; CD97;
Overexpression of circadian clock protein cryptochrome (CRY) 1 alleviates sleep deprivation-induced vascular inflammation in a mouse model
Keywords: cAMP; CRY; cryptochrome; IL; interleukin; TNF; tumor necrosis factor; ICAM-1; intercellular adhesion molecule-1; VCAM-1; vascular cell adhesion molecule-1; NF-κB; nuclear factor; cAMP; cyclic adenosine monophosphate; CLOCK; transcriptional activators circadi
Simultaneous utilization of glucose and xylose via novel mechanisms in engineered Escherichia coli
Keywords: cAMP; CAP; catabolite activator protein; cAMP; cyclic adenosine monophosphate; CCR; carbon catabolite repression; EFB-FH; empty palm fruit bunch fiber hydrolysate; IPTG; isopropyl β-d-1-thiogalactopyranoside; PPP; pentose phosphate pathway; PTS; phosphoenolpyr
The orexin 1 receptor modulates kappa opioid receptor function via a JNK-dependent mechanism
Keywords: cAMP; GPCR; G protein-coupled receptor; OX1R; orexin 1 receptor; KOR; kappa opioid receptor; JNK; c-Jun N-terminal kinase; cAMP; cyclic adenosine monophosphate; VTA; ventral tegmental area; CHO; Chinese hamster ovary; FLIPR; fluorescence in situ plate reader; P
CTNNA3 and SEMA3D: Promising loci for asthma exacerbation identified through multiple genome-wide association studies
Keywords: cAMP; Asthma; exacerbation; genome-wide association study; expression quantitative trait locus; CTNNA3; SEMA3D; biobank; childhood asthma; ABRIDGE; Asthma BioRepository for Integrative Genomic Exploration; ASM; Airway smooth muscle; BioVU; Biobank of Vanderbilt
Aberrant activation of AMP-activated protein kinase contributes to the abnormal distribution of HuR in amyotrophic lateral sclerosis
Keywords: cAMP; A2AR; A2A adenosine receptor; AD; Alzheimer's disease; AICAR; 5-aminoimidazole-4-carboxamide ribonucleotide; ALS; amyotrophic lateral sclerosis; AMPK; AMP-activated protein kinase; AREs; adenylate- and uridylate-rich elements; ELAV; embryonic lethal abn
Nesfatin-1 as a new positive inotrope in the goldfish (Carassius auratus) heart
Keywords: cAMP; AC; adenylate cyclase; β-AR; beta adrenergic receptor; BSA; bovine serum albumin; CO; cardiac output; ERK1/2; extracellular signal-regulated kinases1/2; GAPDH; Glyceraldehyde-3-Phosphate Dehydrogenase; HCNP; hippocampal cholinergic neurostimulating pepti
Synergistic induction of insulin resistance by endothelin-1 and cAMP in 3T3-L1 adipocytes
Keywords: cAMP; Endothelin-1; cAMP; Insulin resistance; Insulin receptor substrate-1; Insulin receptor substrate-2; Adipocytes; β-Adrenergic agonists
Quercetin-3-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside suppresses melanin synthesis by augmenting p38 MAPK and CREB signaling pathways and subsequent cAMP down-regulation in murine melanoma cells
Keywords: cAMP; Persimmon calyx; Melanogenesis; TRPs; p38 MAPK; CREB; cAMP
Nicotinamide ameliorates palmitate-induced ER stress in hepatocytes via cAMP/PKA/CREB pathway-dependent Sirt1 upregulation
Keywords: cAMP; NAM, nicotinamide; PKA, protein kinase A; CREB, cyclic AMP response-element-binding protein; Nampt, nicotinamide phosphoribosyltransferase; NMN, nicotinamide mononucleotide; PDE, phosphodiesteraseNicotinamide; Sirt1; NAD+; Deacetylation; CAMP; PKA
VIP induces NF-κB1-nuclear localisation through different signalling pathways in human tumour and non-tumour prostate cells
Keywords: cAMP; VIP; vasoactive intestinal peptide; EPAC; cAMP/exchange protein directly activated by cAMP; NF-κB; nuclear factor-κB; PKA; cAMP-dependent protein kinase; ERK; extracellular-signal regulated kinase; PI3-K; phosphoinositide 3-kinase; GEF; PKA-independent
The Dictyostelium MAPK ERK1 is phosphorylated in a secondary response to early developmental signaling
Keywords: cAMP; MAPK; mitogen-activated protein kinase; ERK; extracellular-signal regulate kinase; cAMP; cyclic adenosine monophosphate; Pst A; prestalk A; MCCC1; mitochondrial 3-methylcrotonyl-CoA carboxylase α; MAPK; G protein signaling; Dictyostelium; Phosphorylation
Cyclin C interacts with steroid receptor coactivator 2 and upregulates cell cycle genes in MCF-7 cells
Keywords: cAMP; 6His; hexahistidine tag; aa; amino acids; Bcl-2; apoptosis regulator B-cell CLL/lymphoma 2; cAMP; cyclic adenosine monophosphate; CCNC; cyclin C; CCPG1; cell cycle progression protein 1; CDK6; cyclin-dependent kinase 6; cDNA; coding DNA; CXCR4; chemokine
The ABC transporter, AbcB3, mediates cAMP export in D. discoideum development
Keywords: cAMP; ATP-binding cassette transporters; Dictyostelium; cAMP;
cAMP modulation during sheep in vitro oocyte maturation delays progression of meiosis without affecting oocyte parthenogenetic developmental competence
Keywords: cAMP; Oocyte maturation; cAMP; IBMX; Forskolin; Cilostamide; GVBD;
A cost-effective polyphosphate-based metabolism fuels an all E. coli cell-free expression system
Keywords: cAMP; TX-TL; transcription-translation; ATP; adenosine triphosphate; iP; inorganic phosphate; eGFP; enhanced green fluorescent protein; PEP; phosphoenolpyruvate; 3-PGA; 3-phosphoglycerate; NAD; nicotinamide; CoA; coenzyme A; cAMP; adenosine 3â²,5â²-cyclic
PKA is required for the modulation of spinal nociceptive information related to ephrinB-EphB signaling in mice
Keywords: cAMP; ANOVA; analysis of variance; cAMP; cyclic adenosine monophosphate; CCI; chronic constrictive injury; DMSO; dimethyl sulfoxide; DRG; dorsal root ganglion; NMDA; N-methyl-d-aspartate; CREB; cAMP-response element-binding protein; p-CREB; phosphorylated cAMP-
Beta-adrenergic blockade increases GLUT4 and improves glycemic control in insulin-treated diabetic Wistar rats
Keywords: cAMP; ADRB2; beta 2-adrenergic receptor; cAMP; cyclic adenosine monophosphate; EDL; extensor digitorum longus; GLUT4; glucose transporter 4; NFKB; nuclear factor-κB; PKA; cAMP-dependent protein kinase; Slc2a4; solute carrier family 2 member 4; TNF; tumor necro
Combinatorial effects of genistein and sex-steroids on the level of cystic fibrosis transmembrane regulator (CFTR), adenylate cyclase (AC) and cAMP in the cervix of ovariectomised rats
Keywords: cAMP; AC; adenylate cyclase; cAMP; cyclic adenosine monophosphate; cDNA; complementary deoxyribonucleic acid; CFTR; cystic fibrosis transmembrane regulator; EIA; enzyme immunoassay; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HIS; hue-saturation-intensity;
microRNA expression in autonomous thyroid adenomas: Correlation with mRNA regulation
Keywords: cAMP; miRNA; Autonomous adenoma; cAMP; ECM;
Research ReportPyruvate and cilostazol protect cultured rat cortical pericytes against tissue plasminogen activator (tPA)-induced cell death
Keywords: cAMP; Zinc; tPA; Pyruvate; Pericyte cell death; Cilostazol; cAMP;