Keywords: α-CGRP; alpha-calcitonin gene related peptide; Ang; angiopoietin; AE2; anion exchanger 2; ADP; adenosine diphosphate; ADPKD; autosomal dominant polycystic kidney disease; ATP; adenosine triphosphate; ASBT; sodium-dependent bile acid transporter; AQP; aqu
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Keywords: EGFR; Epidermal growth factor receptor; TP53; Tumor protein p53; KRAS; Kirsten rat carcoma viral oncogene; ALK; Anaplastic lymphoma kinase; RTK; Protein receptor tyrosine kinase; TKI; Tyrosine kinase inhibitor; PI3K; Phosphatidylinositol 3-kinase; NSCLC;
Keywords: Epigenetics; Phytochemicals; DNA-methylation; Histone-modification; miRNA; Carcinogenesis; Akt; v-akt murine thymoma viral oncogene homolog 1; AP-1; Activator Protein-1; Bax; BCL2-associated X protein; Bcl2; B-cell CLL/lymphoma 2; Bcl-xL; B-cell lymphoma-
The function and clinical significance of eIF3 in cancer
Keywords: eIFs; eukaryotic translation initiation factors; eIF3; eukaryotic translation initiation factor 3; IRES; internal ribosome entry site; PABP; polyA binding protein; CKIs; cyclin-dependent kinase inhibitors; NER; nucleotide excision repair; GC; gastric carc
Effects of microRNAs on skeletal muscle development
Keywords: HDAC4; histone deacetylase 4; SRF; serum response factor; Pax3; paired box protein pax-3; Pax7; paired box protein pax-7; 3â²UTR; 3â² untranslated region; MEF2A; myocyte-specific enhancer factor 2A; Mef2d; myocyte-specific enhancer factor 2D; Myf5; myog
The reciprocal link between EVI1 and miRNAs in human malignancies
Keywords: EVI1; ecotropic virus integration site-1; MiR; microRNA; 3â²-UTR; 3â²-untranslated regions; AML; acute myeloid leukemia; DNA; deoxyribonucleic acid; RNA; ribonucleic acid; NF-κβ; nuclear factor kappa β; CHIP; Chromatin Immunoprecipitation; c-Myb; c-m
COP9 signalosome subunit 6 mediates PDGF -induced pulmonary arterial smooth muscle cells proliferation
Keywords: Pulmonary arterial smooth muscle cells; Proliferation; COP9 signalosome subunit 6 (CSN6); β-transduction repeat-containing protein (β-TrCP); Cdc25A;
Impact of microRNAs on ischemic stroke: From pre- to post-disease
Keywords: AAV; adeno-associated virus; ABCA1; ATP-binding cassette transporter 1; AGO; argonaute; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionate; AT1R; angiotensin II type 1 receptor; AQPs; aquaporins; BBB; blood-brain barrier; Bcl-6; B-cell lymphoma-6;
Original ArticleAccumulation of cytoplasmic CDC25A in cutaneous squamous cell carcinoma leads to a dependency on CDC25A for cancer cell survival and tumor growth
Keywords: Skin cancer; SCC; CDC25A; 14-3-3; Apoptosis; CDC25A; cell division cycle 25 a; CDK; cyclin-dependent kinase; PLA; proximity ligation assay; SCC; squamous cell carcinoma; UV; ultraviolet;
Steady-state kinetic studies reveal that the anti-cancer target Ubiquitin-Specific Protease 17 (USP17) is a highly efficient deubiquitinating enzyme
Keywords: Ubiquitin Specific Protease 17; DUB3; Ubiquitin; Protein refolding; USP17; Deubiquitinating; DUB; deubiquitinating enzyme; USP; Ubiquitin Specific Protease; Ub; ubiquitin; CDC25A; cell division cycle 25A; RCE1; Ras converting enzyme 1; IPTG; isopropyl β-
PKC-alpha modulation by miR-483-3p in platinum-resistant ovarian carcinoma cells
Keywords: API5; apoptosis inhibitor 5; ARF1; ADP ribosylation factor 3; BCA; bicinchoninic acid; BBC3/PUMA; BCL2 binding component 3; BIRC5; baculoviral IAP (inhibitor of apoptosis) repeat containing 5; CDC25A; cell division cycle 25A; CDK4; cyclin-dependent kinase
Dub3 expression correlates with tumor progression and poor prognosis in human epithelial ovarian cancer
Keywords: Dub3; CDC25A; Ovarian cancer; Proliferation
Serine–Threonine Kinase 38 regulates CDC25A stability and the DNA damage-induced G2/M checkpoint
Keywords: STK38; CDC25A; Degradation; DNA damage; G2/M checkpoint
IGF1 regulation of BOULE and CDC25A transcripts via a testosterone-independent pathway in spermatogenesis of adult mice
Keywords: Spermatogenesis; BOULE; CDC25A; IGF1; Testosterone
Arsenic-induced S phase cell cycle lengthening is associated with ROS generation, p53 signaling and CDC25A expression
Keywords: Arsenite; p53; S phase lengthening; ROS; SESN1; CDC25A;
miR-141-3p inhibits human stromal (mesenchymal) stem cell proliferation and differentiation
Keywords: Human stromal (mesenchymal) stem cell; miRNA; Cell proliferation and differentiation; Wnt signaling; CDC25A;
Proteomic-based identification of multiple pathways underlying n-butylidenephthalide-induced apoptosis in LNCaP human prostate cancer cells
Keywords: 2DE; two-dimensional gel electrophoresis; ABC; ammonium bicarbonate; ACN; acetonitrile; BAD; BCL2 antagonist of cell death; BCL2; B-cell lymphoma 2; BP; n-butylidenephthalide; CCND1; cyclin D1; CDC25A; cell division cycle 25 homolog A; CDK; cyclin depende
Generation of high-producing cell lines by overexpression of cell division cycle 25 homolog A in Chinese hamster ovary cells
Keywords: Chinese hamster ovary cells; Gene amplification; Monoclonal antibody; CDC25A; Cell cycle
Cdc25A promotes cell survival by stimulating NF-κB activity through IκB-α phosphorylation and destabilization
Keywords: Cdc25A; NF-κB; Iκ-Bα; Ubiquitination; Apoptosis;
MicroRNAs in cancer management and their modulation by dietary agents
Keywords: ACTR1A; ARP1 actin-related protein 1 homolog A centractin alpha; AGTR1; angiotensin II receptor type 1; AICDA; activation-induced cytidine deaminase; AKT; v-akt murine thymoma viral oncogene homolog; ALL; acute lymphocytic leukemia; AML; acute myeloid leu
Molecular and Cellular PharmacologyInvolvement of Chk1-Cdc25A-cyclin A/CDk2 pathway in simvastatin induced S-phase cell cycle arrest and apoptosis in multiple myeloma cells
Keywords: Simvastatin; S phase arrest; Chk1; Cyclin dependent kinase 2; Cdc25A;
Absence of polo-like kinase 3 in mice stabilizes Cdc25A after DNA damage but is not sufficient to produce tumors
Keywords: Polo-like kinases; Cdc25A; DNA damage; Checkpoints; Ubiquitinylation
Structural characterization of inhibitor complexes with checkpoint kinase 2 (Chk2), a drug target for cancer therapy
Keywords: ADME; adsorption, distribution, metabolism, and elimination; ADP; adenosine diphosphatase; ATM; ataxia telangiectasia mutated; ATP; adenosine triphosphate; ATR; ataxia telangiectasia and Rad3 related; BRCA1; breast cancer 1; Cdc25a; cell division cycle 25
A role for the cell cycle phosphatase Cdc25a in vitamin D-dependent inhibition of adult rat vascular smooth muscle cell proliferation
Keywords: Vitamin D; Endothelin; Cdk2; Cdc25A; Vascular smooth muscle cell
Inhibition of androgen receptor and Cdc25A phosphatase as a combination targeted therapy in molecular apocrine breast cancer
Keywords: Androgen receptor; Molecular apocrine; Breast cancer; Cdc25A; ERK
Prognostic implication of CDC25A and cyclin E expression on primary breast cancer patients
Keywords: Breast cancer; Ki 67 labeling index; Cyclin E; CDC25A; Survival;
Human Cdc25A phosphatase has a non-redundant function in G2 phase by activating Cyclin A-dependent kinases
Keywords: Cell cycle; Cdc25A; Mitosis; Cyclin A; Cyclin B/Cdk1
Silencing the Metallothionein-2A gene inhibits cell cycle progression from G1- to S-phase involving ATM and cdc25A signaling in breast cancer cells
Keywords: Metallothionein; Cell cycle; Breast cancer; ATM; cdc25A
Design and synthesis of N-alkyl oxindolylidene acetic acids as a new class of potent Cdc25A inhibitors
Keywords: Cdc25A; Dysidiolide; Inhibitor
The effects of over-expression and suppression of Cdc25A on the S-phase checkpoint induced by benzo(a)pyrene
Keywords: Benzo(a)pyrene (BaP); Cdc25A; Cell cycle; S-phase checkpoint
CDC25A phosphatase controls meiosis I progression in mouse oocytes
Keywords: Resumption of meiosis; Meiotic maturation; Mouse oocytes; CDC25A; CDC25B; CDK1; MAPK; Spindle formation;
The Cdc25A is involved in S-phase checkpoint induced by benzo(a)pyrene
Keywords: Benzo(a)pyrene (BaP); Cdc25A; Cell cycle; S-phase checkpoint
The vitamin-like dietary supplement para-aminobenzoic acid enhances the antitumor activity of ionizing radiation
Keywords: Para-aminobenzoic acid; P21CIP1; CDC25A; Apoptosis; Tumor growth;
Expression of cdc25B and cdc25A in medullary thyroid carcinoma: cdc25B expression level predicts a poor prognosis
Keywords: Medullary carcinoma; Thyroid; cdc25B; cdc25A; Immunohistochemistry;
Differential impact of diverse anticancer chemotherapeutics on the Cdc25A-degradation checkpoint pathway
Keywords: DNA damage; Cell cycle; Cdc25A; Checkpoint; Chk1/2 kinase; Anticancer drugs; Cyclin/CDK kinases; DNA synthesis; Cancer;