دانلود مقالات ISI درباره Cdca + ترجمه فارسی

Bile acid receptor TGR5 overexpression is associated with decreased intestinal mucosal injury and epithelial cell proliferation in obstructive jaundice

Keywords: ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; BDL; bile duct ligation; CDCA; chenodeoxycholic acid; DAO; diamine oxidase; DCA; deoxycholic acid; D-lactate; D(-)-lactic acid; EdU; 5-ethynyl-2′-deoxyuridine; G

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of Bile Acids Responsible for Inhibiting the Bile Salt Export Pump, Leading to Bile Acid Accumulation and Cell Toxicity in Rat Hepatocytes

Keywords: biliary excretion; in vitro models; toxicology; bile acid transporters; efflux pumps; BA; bile acid; BSEP; bile salt export pump; CA; cholic acid; CDCA; chenodeoxycholic acid; CsA; cyclosporin A; DCA; deoxycholic acid; DILI; drug-induced liver injury; DM

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Cardiopulmonary protective effects of the selective FXR agonist obeticholic acid in the rat model of monocrotaline-induced pulmonary hypertension

Keywords: ACE2; angiotensin-converting enzyme 2; Ach; acetylcholine; BA; bile acid; BMP2; bone morphogenetic protein 2; BMPR1A; bone morphogenetic protein receptor 1-a; BW; body weight; CDCA; chenodeoxycholic acid; cGMP; cyclic guanosine monophosphate; COX2; cycloo

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Farnesoid X receptor regulates SULT1E1 expression through inhibition of PGC1α binding to HNF4α

Keywords: CDCA; chenodeoxycholic acid; ChIP; chromatin immunoprecipitation assays; Co-IP; co-immunoprecipitation; CYP7A1; cholesterol 7α-hydroxylase; DMEM; Dulbecco's Modified Eagle Medium/High glucose; DMSO; dimethyl sulfoxide; FBS; fetal bovine serum; FXR; far

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Deletion of liver-specific STAT5 gene alters the expression of bile acid metabolism genes and reduces liver damage in lithogenic diet-fed mice

Keywords: STAT5; signal transducer and activator of transcription 5; GH; growth hormone; IGF-1; insulin-like growth factor-1; LDLR; low-density lipoprotein receptor; STAT5 LKO; liver-specific STAT5 knock-out; STAT5 fl/fl; STAT5 flox/flox; TG; triacylglycerol; ChMCs

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Promotion of classic neutral bile acids synthesis pathway is responsible for cholesterol-lowing effect of Si-miao-yong-an decoction: Application of LC-MS/MS method to determine 6 major bile acids in rat liver and plasma

Keywords: SMYAD; Si-miao-yong-an decoction; TCM; traditional Chinese medicine; TC; total cholesterol; TG; total triglyceride; LDL-c; low-density lipoprotein cholesterol; HDL-c; high-density lipoprotein cholesterol; CA; cholic acid; CDCA; chenodeoxycholic acid; TCA;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

Ageing sensitized by iPLA2β deficiency induces liver fibrosis and intestinal atrophy involving suppression of homeostatic genes and alteration of intestinal lipids and bile acids

Keywords: ACC; acetyl-CoA carboxylase; ATF6; activating transcription factor6; AB-PAS; alcian blue-periodic acidschiff; ACC; acetyl-CoA carboxylase; ACSL; long-chain acyl-CoA synthetase; Bad; Bcl-2-associated death promoter; Bax; Bcl-2-like protein 4; Bcl-2; B-cell

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Improved synthesis of glycine, taurine and sulfate conjugated bile acids as reference compounds and internal standards for ESI-MS/MS urinary profiling of inborn errors of bile acid synthesis

Keywords: EEDQ; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; DEPC; diethyl phosphorocyanidate; DPPA; diphenyl phosphoryl azide; SO3-TEA; sulfur trioxide-triethylamine complex; SO3-TMA; sulfur trioxide-trimethylamine complex; SO3-DMA; sulfur trioxide-N,N-dimethyl

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2017 سفارش ترجمه

Steroidogenic acute regulatory protein (StAR) overexpression attenuates HFD-induced hepatic steatosis and insulin resistance

Keywords: StAR; steroidogenic acute regulatory protein; NAFLD; non-alcoholic fatty liver disease; HFD; high-fat diet; DMEM; Dulbecco's Modified Eagle Medium; PBS; phosphate buffered solution; FBS; fetal bovine serum; ITS-X; insulin-transferrin-selenium-ethanolamine

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2017 سفارش ترجمه

Impact of microbial derived secondary bile acids on colonization resistance against Clostridium difficile in the gastrointestinal tract

Keywords: Clostridium difficile; Secondary bile acids; Colonization resistance; Gut microbiota; Antibiotics; GI; Gastrointestinal; CDI; Clostridium difficile infection; LC-MS; Liquid chromatography mass spectrometry; CA; cholate; CDCA; chenodeoxycholate; DCA; deoxy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

The Farnesoid X Receptor: Good for BAD

Keywords: Bile Acid Diarrhea; Enterohepatic Circulation; FGF-19; Chloride Secretion; Epithelium; ASBT; apical sodium-linked bile acid transporter; BAD; bile acid diarrhea; C4; 7α-hydroxy-4-cholesten-3-one; CA; cholic acid; CDCA; chenodeoxycholic acid; DCA; deoxych

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Oleanolic acid-NO donor-platinum(II) trihybrid molecules: Targeting cytotoxicity on hepatoma cells with combined action mode and good safety

Keywords: CDCA; endogenous ligand chenodeoxycholic acid; FXR; farnesoid X receptor; FXR-LBD; the ligand binding domain of farnesoid X receptor; Hb; hemoglobin; ISDN; isosorbide dinitrate; NO; nitric oxide; OA; oleanolic acid; OA-NO; oleanolic acid nitric oxide dono

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Activation of the Farnesoid X-receptor in breast cancer cell lines results in cytotoxicity but not increased migration potential

Keywords: CDCA; chenodexoycholic acid; ER; oestrogen receptor; FXR; Farnesoid X-receptor; Her2; human epidermal growth factor receptor 2; PR; progesterone receptor; TNBC; triple negative breast cancer; Apoptosis; Autophagy; Nuclear receptor; Triple negative breast

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

The antiandrogen flutamide is a novel aryl hydrocarbon receptor ligand that disrupts bile acid homeostasis in mice through induction of Abcc4

Keywords: FLU; flutamide; AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor nuclear translocator; CYP; cytochrome P450; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin; 3-MC; 3-methylcholanthrene; ABCC4; ATP-binding cassette sub-family C member 4; MRP4; mul

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

UDCA and CDCA alleviate 17α-ethinylestradiol-induced cholestasis through PKA-AMPK pathways in rats

Keywords: PKA; AMPK; UDCA; CDCA; ICP;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Bile acids-mediated overexpression of MUC4 via FAK-dependent c-Jun activation in pancreatic cancer

Keywords: Bile acids; Pancreatic cancer; MUC4; FAK; FXR; c-Jun; PC; pancreatic cancer; PDAC; pancreatic ductal adenocarcinoma; BA; bile acids; DCA; deoxycholic acid; CDCA; chenodeoxycholic acid; FXR; farnesoid-x-receptor; FAK; focal adhesion kinase; MAPK; mitogen a

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Chenodeoxycholic acid significantly impacts the expression of miRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes

Keywords: ABC; ATP-binding cassette transporter; AGPAT2; 1-acylglycerol-3-phosphate O-acyltransferase; AhR; arylhydrocarbon receptor; AKR1C1; aldo-keto reductase 1C1; APO; apolipoprotein; ASBT; apical sodium dependent bile acid transporter; BAs; bile acids; BSEP; b

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2016 سفارش ترجمه

An Intestinal Microbiota-Farnesoid X Receptor Axis Modulates Metabolic Disease

Keywords: Bile Acids; Farnesoid X Receptor; Metabolic Disease; Ceramides; BSH; bile salt hydrolase; CA; cholic acid; cAMP; cyclic adenosine monophosphate; CDCA; chenodeoxycholic acid; CYP; cytochrome P450s; CYP7A1; CYP with cholesterol 7α-hydroxylase; DCA; deoxych

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

Investigation of the dominant positive effect of porcine farnesoid X receptor (FXR) splice variant 1

Keywords: CAR; constitutive androstane receptor; PXR; pregnane X receptor; FXR; farnesoid X receptor; CYP3A4; cytochrome P450 3A4; SULT2A1; hydroxysteroid sulfotransferase; UGT2B4; UDP-glucuronosyltransferase 2B4; GRβ; glucocorticoid receptor β; ERE; estrogen res

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Apparent underdiagnosis of Cerebrotendinous Xanthomatosis revealed by analysis of ~ 60,000 human exomes

Keywords: CTX; Incidence; Bioinformatics; Population genetics; IEM; Xanthoma; Cataract; Cholestanol; Sterol; Bile acids; Cholic acid; CDCA;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Altered intestinal bile salt biotransformation in a cystic fibrosis (Cftr−/−) mouse model with hepato-biliary pathology

Keywords: CF; Cystic fibrosis; Cftr; Cystic fibrosis transmembrane conductance regulator; CFLD; Cystic fibrosis related liver disease; Unc; University of North Carolina; CA; Cholic acid; DCA; Deoxycholic acid; CDCA; Chenodeoxycholic acid; HDCA; Hyodeoxycholic acid;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleGut microbiota inhibit Asbt-dependent intestinal bile acid reabsorption via Gata4

Keywords: BA; bile acid; Asbt; apical sodium-dependent bile acid transporter; KO; knock-out; iKO; intestinal-specific knock-out; WT; wildtype; CA; cholic acid; CDCA; chenodeoxycholic acid; MCA; muricholic acid; UDCA; urodeoxycholic acid; Gut microbiota; Intestinal

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Effect of chenodeoxycholic acid and sodium hydrogen sulfide in dinitro benzene sulfonic acid (DNBS) - Induced ulcerative colitis in rats

Keywords: 6E-CDCA; 6-ethyl chenodeoxycholic acid; ALT; alanine aminotransferase; ANOVA; analysis of variance; AST; aspartate aminotransferase; CA; cholic acid; CDCA; chenodeoxycholic acid; CSE; cystathionine-γ-lyase; CaCl2; calcium chloride; CO2; carbon dioxide; D

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis

Keywords: LCA; lithocholic acid; UDCA; ursodeoxycholic acid; CDCA; chenodeoxycholic acid; DCA; deoxycholic acid; CA; cholic acid; TCA; taurocholic acid; GCDC; glycochenodeoxycholic acid; TCDC; taurochenodeoxycholic acid; GCA; glycocholic acid; GDCA; glycodeoxycholi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Sensitization to autoimmune hepatitis in group VIA calcium-independent phospholipase A2-null mice led to duodenal villous atrophy with apoptosis, goblet cell hyperplasia and leaked bile acids

Keywords: AB-PAS; alcian blue-periodic acid schiff; AIH; autoimmune hepatitis; ALT; alanine aminotransferase; AP; alkaline phosphatase; AST; aspartate aminotransferase; Bcl-2; B-cell lymphoma 2; CA; cholic acid; CCL; chemokine ligand; CCR; chemokine receptor; CDCA;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

ReviewNew paradigms in the treatment of hepatic cholestasis: From UDCA to FXR, PXR and beyond

Keywords: AE2; anion exchanger 2; ASBT; apical sodium bile salt transporter; BA; bile acid; CA; cholic acid; CDCA; chenodeoxycholic acid; CFALD; cystic fibrosis-associated liver disease; CFTR; cystic fibrosis transmembrane conductance regulator; DCA; deoxycholic ac

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Original ResearchFull Report: Clinical-LiverEfficacy of Obeticholic Acid in Patients With Primary Biliary Cirrhosis and Inadequate Response to Ursodeoxycholic Acid

Keywords: Cholestasis; Bile Acids; FXR; Dose Study; AE; adverse event; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; BA; bile acid; C4; BA precursor C4 (7α-hydroxy-4-cholesten-3-one); CDCA; chenodeoxycholic acid; DCA; d

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

Oleanolic acid attenuates obstructive cholestasis in bile duct-ligated mice, possibly via activation of NRF2-MRPs and FXR antagonism

Keywords: OA; oleanolic acid; LCA; lithocholic acid; UDCA; ursodeoxycholic acid; PBC; primary biliary cirrhosis; PSC; primary sclerosing cholangitis; MRP; multidrug resistance-associated protein; NRF2; nuclear factor-E2-related factor; siRNA; small interfering RNA;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2015 سفارش ترجمه

Stereoselective synthesis, biological evaluation, and modeling of novel bile acid-derived G-protein coupled Bile acid receptor 1 (GP-BAR1, TGR5) agonists

Keywords: GPCR; G protein-coupled receptor; BAs; bile acids; CDCA; chenodeoxycholic acid; CA; cholic acid; LCA; lithocholic acid; UDCA; ursodeoxycholic acid; FXR; farnesoid X receptor; NRs; nuclear receptors; LBD; ligand-binding domain; cAMP; cyclic adenosine monop

دانلود رایگان متن کامل مقاله ISI 62 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis and evaluation of 18 F-labeled bile acid compound: A potential PET imaging agent for FXR-related diseases

Keywords: Bile acid; FXR; PET imaging; 18 F; CDCA; Click chemistry

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Liver-specific induction of Abcg5 and Abcg8 stimulates reverse cholesterol transport in response to ezetimibe treatment

Keywords: EZ; ezetimibe; RCT; reverse cholesterol transport; Abcg5/g8; Abcg5 and Abcg8; KO; knock-out; WT; wild-type; PHH; primary human hepatocytes; CDCA; chenodeoxycholic acid; BMM; bone marrow macrophages; TICE; trans-intestinal cholesterol excretion; Npc1l1; At

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Conformational dynamics of human FXR-LBD ligand interactions studied by hydrogen/deuterium exchange mass spectrometry: Insights into the antagonism of the hypolipidemic agent Z-guggulsterone

Keywords: HDX; hydrogen/deuterium exchange; LC-ESI-MS; liquid chromatography electrospray ionization mass spectrometry; FXR-LBD; farnesoid X receptor ligand binding domain; LBC; ligand binding cavity; CDCA; chenodeoxycholic acid; GG; Z-guggulsterone; 6ECDCA; 6-et

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Toxicity and intracellular accumulation of bile acids in sandwich-cultured rat hepatocytes: Role of glycine conjugates

Keywords: BAs; bile acids; BAAT; bile acid CoA: amino acid N-acyltransferase; BEI; biliary excretion index; BSEP/Bsep; bile salt export pump (human/rat); DMSO; dimethyl sulfoxide; CDCA; chenodeoxycholic acid; CA; cholic acid; FBS; Fetal Bovine Serum GCDCA, glycoche

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Vitamin D Receptor Activation Down-regulates the Small Heterodimer Partner and Increases CYP7A1 to Lower Cholesterol

Keywords: Liver; Bile Acid; Farnesoid X Receptor; Transcriptional Regulation; Asbt; rodent apical sodium dependent bile acid transporter; CDCA; chenodeoxycholic acid; ChIP; chromatin immunoprecipitation; Cyp7a1/CYP7A1; rodent/human cholesterol 7α-hydroxylase; 1,25

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2014 سفارش ترجمه

Cholestatic effect of epigallocatechin gallate in rats is mediated via decreased expression of Mrp2

Keywords: Epigallocatechin gallate; Bile formation; Cholestasis; Bile acids; Asbt; apical sodium-dependent bile salt transporter; ALT; alanine transaminase; AST; aspartate transaminase; Bsep; bile salt exporting pump; CDCA; chenodeoxycholic acid; Cyp7a1; cholestero

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Aberrant activation of M phase proteins by cell proliferation-evoking carcinogens after 28-day administration in rats

Keywords: Carcinogen; M phase; Cell proliferation; Immunohistochemical analysis; SDM; sulfadimethoxine; PEITC; phenylethyl isothiocyanate; BHA; butylated hydroxyanisole; CC; catechol; PhIP; 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine; CDCA; chenodeoxycholic aci

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Farnesoid X receptor directly regulates xenobiotic detoxification genes in the long-lived Little mice

Keywords: FXR; farnesoid X receptor; RXR; retinoid X receptor; Ghrhr; growth hormone-releasing hormone receptor; GH; growth hormone; IGF; insulin-like growth factor; FXREs; FXR response elements; IR; inverted repeat; DR; direct repeat; ER; everted repeat; TSS; tran

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Disruption of Stard10 gene alters the PPARα-mediated bile acid homeostasis

Keywords: StAR; steroidogenic acute regulatory protein; START; StAR-related lipid transfer; STARD10/Stard10; START domain containing 10; WT; wild type; ASBT/Asbt; apical sodium dependent bile acid transporter; STARD2/Stard2; START domain containing 2; CA; cholic ac

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of 15d-PGJ2 as an antagonist of farnesoid X receptor: Molecular modeling with biological evaluation

Keywords: 15d-PGJ2; 15-deoxy-Δ12,14-PGJ2; AA; arachidonic acid; PPARγ; peroxisome proliferator-activated receptor γ; FXR; farnesoid X receptor; SPR; surface plasmon resonance; FQ; fluorescence quenching; HTRF; homo time-resolved fluorescence; BSEP; bile-salt exp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Bile Acids Increase Levels of MicroRNAs 221 and 222, Leading to Degradation of CDX2 During Esophageal Carcinogenesis

Keywords: Cancer; Tumor Development; Mouse Model; Post-Transcriptional Modification; BE; Barrett's esophagus; CA; cholic acid; CDCA; chenodeoxycholic acid; CDX2; caudal-related homologue 2; EAC; esophageal adenocarcinoma; FXR; nuclear bile acid receptor/farnesoid X

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Differential activation of the human farnesoid X receptor depends on the pattern of expressed isoforms and the bile acid pool composition

Keywords: Glycoconjugated bile acids; Tauroconjugated bile acids; Ileum; Liver; Nuclear receptor; ACA; allocholic acid; BA; bile acid; BSEP; bile salt export pump; CDCA; chenodeoxycholic acid; CA; cholic acid; DCA; deoxycholic acid; FGF; fibroblast growth factor; F

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Analytical strategies for characterization of oxysterol lipidomes: Liver X receptor ligands in plasma

Keywords: API; atmospheric pressure ionization; CDCA; chenodeoxycholic acid; CTX; cerebrotendinous xanthomatosis; EADSA; enzyme-assisted derivatization for sterol analysis; DHEA; dehydroepiandrosterone; ESI; electrospray ionization; FT; Fourier transform; FWHM; ful

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Modulation of farnesoid X receptor results in post-translational modification of poly (ADP-ribose) polymerase 1 in the liver

Keywords: 2D-DIGE; two-dimensional gel electrophoresis; Alc1; amplified in liver cancer 1; Aldh2; mitochondrial aldehyde dehydrogenase 2; CDCA; chenodeoxycholic acid; Eno1; enolase1; FXR; farnesoid X receptor; FXR-KO; FXR-knockout; HBVCP; HBV core promoter; HCC; he

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Methods for Diagnosis of Bile Acid Malabsorption in Clinical Practice

Keywords: SeHCAT; C4; Glycocholate; Fecal; Diarrhea; ASBT; Na+-dependent bile salt transporter; BA; bile acid; BAM; bile acid malabsorption; CA; cholic acid; CDCA; chenodeoxycholic acid; CYP7A1; cholesterol 7α hydroxylase; C4; 7 α-hydroxy-4-cholesten-3-one; DCA;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Characterization of urinary bile acids in a pediatric BRIC-1 patient: Effect of rifampicin treatment

Keywords: RFP; rifampicin; BRIC; benign recurrent intrahepatic cholestasis; GGT; γ-glutamyltransferase; PFIC-1; progressive familial intrahepatic cholestasis type 1; UGT; uridine diphosphate glucuronosyltransferase; CYP; cytochrome P450; AST; aspartate aminotransf

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

The bile steroid chenodeoxycholate is a potent antagonist at NMDA and GABAA receptors

Keywords: BS; bile steroids; GABAA; γ-aminobutyric acid type A; CDCA; chenodeoxycholic acid (also chenodeoxycholate); MEA; microelectrode array; SSB; steady state block; DH; dehydrocholic acid (also dehydrocholate); DCA; deoxycholic acid (also deoxycholate); TCDCA

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Farnesoid X Receptor Targeting for Hepatitis C: Study Protocol for a Proof-of-concept Trial

Keywords: clinical trial; farnesoid X receptor; hepatitis C; proof of concept; essai clinique; récepteur nucléaire des acides biliaires; hépatite C; preuve de concept; Afssaps; french Agency for the Safety of Health Products (currently ANSM); BA; bile acid; CBC;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

HPLC/ELSD analysis of amidated bile acids: An effective and rapid way to assist continuous flow chemistry processes

Keywords: BA; bile acid; BS; bile salt; UDCA; ursodeoxycholic acid; CDCA; chenodeoxycholic acid; DCA; deoxycholic acid; CA; cholic acid; HPLC; high-performance liquid chromatography; ELSD; evaporative light scattering detector; MS; mass spectrometry; DAD; diod arra

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Investigation of imatinib and other approved drugs as starting points for antidiabetic drug discovery with FXR modulating activity

Keywords: CATS2D; chemically advanced template search 2D; CDCA; chenodeoxycholic acid; CHF; congestive heart failure; CML; chronic myeloid leukemia; COPD; chronic obstructive pulmonary disease; DMEM; Dulbeccós modified eagle medium; DMSO; dimethylsulfoxide; FCS; f

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleEffect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health

Keywords: UDCA; ursodeoxycholic acid; PBC; primary biliary cirrhosis; ASBT; apical sodium-dependent bile acid transporter; FXR; farnesoid X receptor; PXR; pregnane X receptor; VDR; vitamin D receptor; CA; cholic acid; CDCA; chenodeoxycholic acid; DCA; deoxycholic a

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه