دانلود مقالات ISI درباره Cftr + ترجمه فارسی

Neutrophils from F508del cystic fibrosis patients produce IL-17A and express IL-23 - dependent IL-17RC

Keywords: Cystic fibrosis; CFTR; F508del; Neutrophil; IL-17A; IL-17RC; IL-17A receptor; MMP9; Elastase; Pseudomonas aeruginosa; F508del mice

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

CFTR and/or pancreatitis susceptibility genes mutations as risk factors of pancreatitis in cystic fibrosis patients?

Keywords: Pancreatitis; Cystic fibrosis; CFTR; Modifier genes; Bicarbonate; Next Generation Sequencing;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Assessment of epithelial sodium channel variants in nonwhite cystic fibrosis patients with non-diagnostic CFTR genotypes

Keywords: Cystic fibrosis; CF; Epithelial sodium channel; ENaC; SCNN1; Molecular diagnosis; CFTR; Nonwhite

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Microfluidic hydrogel arrays for direct genotyping of clinical samples

Keywords: Hydrogel microarray; SNP detection; Clinical diagnostics; PDMS microfluidics; CFTR; Electrophoresis;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of ceramide de novo synthesis by myriocin produces the double effect of reducing pathological inflammation and exerting antifungal activity against A. fumigatus airways infection

Keywords: BALT; Bronchial Associated Lymphoid Tissue; CF; Cystic Fibrosis; COPD; Chronic Obstructive Pulmonary Disease; CFTR; CF transmembrane conductance regulator; CFU; Colony Forming Units; Gapdh; glyceraldehyde-3-phosphate dehydrogenase; HO1; heme oxygenase 1;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Faecal proteomics: A tool to investigate dysbiosis and inflammation in patients with cystic fibrosis

Keywords: ACE; angiotensin converting enzyme; CF; cystic fibrosis; CFTR; cystic fibrosis transmembrane conductance regulator; DIOS; distal intestinal obstruction syndrome; DMBT1; deleted in malignant brain tumours 1; GI; gastro-intestinal; GO; gene ontology; LC-MS;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Effect of CFTR modifiers on arylsulfatase B activity in cystic fibrosis and normal human bronchial epithelial cells

Keywords: Cystic fibrosis; CFTR; Arylsulfatase B; Chondroitin 4-sulfate; Glycosaminoglycans; Corrector; Potentiator; Interleukin-8; Interleukin-6; Neutrophil migration

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleRescue of defective ATP8B1 trafficking by CFTR correctors as a therapeutic strategy for familial intrahepatic cholestasis

Keywords: CFTR; cystic fibrosis transmembrane conductance regulator; 4-PBA; 4-phenyl butyric acid; SAHA; suberoylanilide hydroxamic acid; NB-DNJ; N-butyldeoxynojirimycin; BRIC; benign recurrent intrahepatic cholestasis; PFIC; progressive familial intrahepatic chole

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Phosphatidylcholine passes through lateral tight junctions for paracellular transport to the apical side of the polarized intestinal tumor cell-line CaCo2

Keywords: CFTR; cystic fibrosis transmembrane conductance regulator; ESI-MS/MS; electrospray ionization tandem mass spectrometry; FCS; fetal calf serum; LPC; lysophosphatidylcholine; PBS; phosphate-buffered saline; PC; phosphatidylcholine; PE; phosphatidylethanolam

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Heterodimerization with the β1 subunit directs the α2 subunit of nitric oxide-sensitive guanylyl cyclase to calcium-insensitive cell-cell contacts in HEK293 cells: Interaction with Lin7a

Keywords: ANOVA; analysis of variance; DEA/NO; 2,2-diethyl-1-nitroso-oxyhydrazine; CFTR; cystic fibrosis transmembrane conductance regulator; CFP; cyan fluorescent protein; CLSM; confocal laser scanning microscopy; FLIM; fluorescence-lifetime imaging microscopy; HE

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Creation and characterization of an airway epithelial cell line for stable expression of CFTR variants

Keywords: CFBE; CFTR; Cystic fibrosis model; Ivacaftor; RNA sequencing;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Structure of wild type and mutant F508del CFTR: A small-angle X-ray scattering study of the protein-detergent complexes

Keywords: CFTR; F508del; Cystic fibrosis; SAXS; Contrast variation; Detergent-protein complex;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Polymorphic variants of MRP4/ABCC4 differentially modulate the transport of methylated arsenic metabolites and physiological organic anions

Keywords: AsIII; arsenite; AsV; arsenate; As2O3; arsenic trioxide; ABC; ATP-binding cassette; CFTR; cystic fibrosis transmembrane conductance regulator; DAPI; 4′,6-diamidino-2-phenylindole; DMAV; dimethylarsinic acid; DMAIII; dimethylarsinous acid; E217βG; 17β-

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Evaluation of a systems biology approach to identify pharmacological correctors of the mutant CFTR chloride channel

Keywords: CFTR; Chloride channel; F508del; Corrector; Systems biology;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

CFTR Activator Increases Intestinal Fluid Secretion and Normalizes Stool Output in a Mouse Model of Constipation

Keywords: CFTR; Constipation; High-Throughput Screening; LoperamidecAMP, cyclic adenosine monophosphate; CFTR, cystic fibrosis transmembrane conductance regulator; CSBM, complete spontaneous bowel movement; DMSO, dimethyl sulfoxide; EC50, half-maximal effective con

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Reviewc- Src and its role in cystic fibrosis

Keywords: c-Src; Cystic fibrosis; CFTR; Intracellular chloride; IL-1β; PP2; IL1RN;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Comparative ex vivo, in vitro and in silico analyses of a CFTR splicing mutation: Importance of functional studies to establish disease liability of mutations

Keywords: Cystic fibrosis; CFTR; Splicing mutation; Alternative splicing; In silico predictions

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Reviews and PerspectivesReviews in Basic and Clinical Gastroenterology and HepatologyOrganoid Models of Human Gastrointestinal Development and Disease

Keywords: Gut Organoids; Gastrointestinal Development; Gastrointestinal Regeneration; Gastrointestinal Disease; BE; Barrett's esophagus; CF; cystic fibrosis; CFTR; cystic fibrosis transmembrane conductance regulator; 3D; 3-dimensional; DSS; dextran sodium sulfate

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Advances in therapeutic CRISPR/Cas9 genome editing

Keywords: Cas9; CRISPR-associated protein 9; cccDNA; covalently closed circular DNA; CCR5; chemokine receptor 5; CFTR; cystic fibrosis transmembrane conductance regulator; CRISPRs; clustered regularly interspaced short palindromic repeats; crRNA; CRISPR RNA; Crygc;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

The Development of Spasmolytic Polypeptide/TFF2-Expressing Metaplasia (SPEM) During Gastric Repair Is Absent in the Aged Stomach

Keywords: Epithelial Regeneration; Gastric Cancer; Human Gastric Organoids; CD44v; CD44v; variant isoform of CD44; Cftr; cystic fibrosis transmembrane conductance regulator; CgA; chromagranin A; Clu; Clusterin; Ctss; cathepsin S; Dmbt1; deleted in malignant brain t

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2016 سفارش ترجمه

Effects of Bisphenol A on ion channels: Experimental evidence and molecular mechanisms

Keywords: AMPA; α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate; BPA; Bisphenol A; ER; estrogen receptor; CFTR; cystic fibrosis transmembrane conductance regulator; GABAA; gamma-aminobutyric acid type A; EDCs; endocrine-disrupting chemicals; GPR30 or GPER; G-pr

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2016 سفارش ترجمه

Changes in lipid raft proteome upon TNF-α stimulation of cystic fibrosis cells

Keywords: Cystic fibrosis; CFTR; Lipid rafts; GPCR; SILAC; Inflammation;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Research paperMutation and new polymorphisms insight in introns 11 to 14a of CFTR gene of northern Iranian cystic fibrosis patients

Keywords: CF; cystic fibrosis; CFTR; cystic fibrosis transmembrane conductance regulator; ABC; ATP-binding cassette; ENaC; epithelial sodium channel; bp; base pair; RDB; reverse dot blot; PCR; polymerase chain reaction; Cystic fibrosis; CFTR gene; Mutation; Polymor

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

The Role of Ivacaftor in Severe Cystic Fibrosis in a Patient With the R117H Mutation

Keywords: CF; cystic fibrosis; CFQ-R; Cystic Fibrosis Questionnaire Revised; CFTR; cystic fibrosis conductance transmembrane regulator; HRCT; high-resolution CT;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

A bioassay using intestinal organoids to measure CFTR modulators in human plasma

Keywords: CFTR; Intestinal organoids; VX-770; Pharmacokinetics; Personalized medicine;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Clinical expression of patients with the D1152H CFTR mutation

Keywords: CF; cystic fibrosis; CFTR; cystic fibrosis transmembrane conductance regulator; PI; pancreatic insufficiency; PS; pancreatic sufficiency; CFTR-RD; CFTR related disorders; CBAVD; congenital bilateral absence of vas deferens; SC; sweat chloride; W; weight;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Diverse roles of LPA signaling in the intestinal epithelium

Keywords: LPA; lysophosphatidic acid; IEC; intestinal epithelial cell; IBD; inflammatory bowel disease; CRC; colorectal cancer; PA; phosphatidic acid; PLA; phospholipase A; ATX; autotaxin; YAMC; young adult mouse colonic epithelium; MSIE; mouse small intestinal epi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Conservation of CFTR codon frequency through primates suggests synonymous mutations could have a functional effect

Keywords: CFTR; Synonymous mutations; Codon frequency conservation; Cystic fibrosis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Luminal acetylcholine does not affect the activity of the CFTR in tracheal epithelia of pigs

Keywords: CFTR; Non-neuronal acetylcholine; Tracheal epithelium; Transepithelial ion transport; Cl− secretion; Pig;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Altered intestinal bile salt biotransformation in a cystic fibrosis (Cftr−/−) mouse model with hepato-biliary pathology

Keywords: CF; Cystic fibrosis; Cftr; Cystic fibrosis transmembrane conductance regulator; CFLD; Cystic fibrosis related liver disease; Unc; University of North Carolina; CA; Cholic acid; DCA; Deoxycholic acid; CDCA; Chenodeoxycholic acid; HDCA; Hyodeoxycholic acid;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Cold acclimation allows regulation of chloride secretion in a eurythermic teleost fish Fundulus heteroclitus

Keywords: Mitochondrion-rich cell; Opercular epithelium; CFTR; NKCC; Eurythermic; Euryhaline; Adrenergic receptor

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Evidence against resveratrol as a viable therapy for the rescue of defective ΔF508 CFTR

Keywords: CF; cystic fibrosis; CFTR; cystic fibrosis transmembrane conductance regulator; DMEM; Dulbecco's modified Eagle Medium; ENaC; epithelial sodium channel; IBMX; isobutyl-methyl xanthine; SDS-PAGE; sodium dodecylsulphate polyacrylamide gel electrophoresis; W

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Randomized, single blind, controlled trial of inhaled glutathione vs placebo in patients with cystic fibrosis

Keywords: CF; cystic fibrosis; GSH; glutathione; CFTR; cystic fibrosis transmembrane regulator; FEV1; forced expiratory volume in 1 s; FVC; forced vital capacity; FEF25-75; flow at the mid-portion of forced vital capacity; 6MWT; six minute walking test; BMI; bod

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Concentration of fractional excretion of nitric oxide (FENO): A potential airway biomarker of restored CFTR function

Keywords: ATS; American Thoracic Society; BMI; body mass index; CF; cystic fibrosis; CFTR; cystic fibrosis transmembrane conductance regulator; CI; confidence interval; COPD; chronic obstructive pulmonary disease; FENO; fractional excretion of nitric oxide; FEV1; f

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Stimulation of β2-adrenergic receptor increases CFTR function and decreases ATP levels in murine hematopoietic stem/progenitor cells

Keywords: Adrenergic receptor; ATP; CFTR; Hematopoietic stem/progenitor cells;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Function, pharmacological correction and maturation of new Indian CFTR gene mutations

Keywords: CBAVD; congenital bilateral absence of the vas deferens; CF; cystic fibrosis; CFTR; cystic fibrosis transmembrane conductance regulator; GFP; green fluorescent protein; WT-CFTR; wild-type CFTR; Missense CF mutations; India; L69H-CFTR; S549N-CFTR; Low temp

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Cigarette smoke exposure reveals a novel role for the MEK/ERK1/2 MAPK pathway in regulation of CFTR

Keywords: CFTR; Cigarette smoke; Airway epithelial cell; MAPK pathway;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Glutathione metabolism links FOXRED1 to NADH:ubiquinone oxidoreductase (complex I) deficiency: A hypothesis

Keywords: ABC; ATP-binding cassette; ADH3; alcohol dehydrogenase 3; ALDH; aldehyde dehydrogenase; CFTR; cystic fibrosis transmembrane conductance regulator; CPS1; carbamoyl phosphate synthase; DMGDH; dimethylglycine dehydrogenase; DHF; dihydrofolate; DMGO; dimethyl

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Combinatorial effects of genistein and sex-steroids on the level of cystic fibrosis transmembrane regulator (CFTR), adenylate cyclase (AC) and cAMP in the cervix of ovariectomised rats

Keywords: AC; adenylate cyclase; cAMP; cyclic adenosine monophosphate; cDNA; complementary deoxyribonucleic acid; CFTR; cystic fibrosis transmembrane regulator; EIA; enzyme immunoassay; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HIS; hue-saturation-intensity;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

The hsa-miR-125a/hsa-let-7e/hsa-miR-99b cluster is potentially implicated in Cystic Fibrosis pathogenesis

Keywords: Cystic Fibrosis; MicroRNAs; CFTR; SNPs

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

The role of AGR2 and AGR3 in cancer: Similar but not identical

Keywords: AGR2; AGR3; PDI family; Cancer; AA; amino acids; ALS; familial amyotrophic lateral sclerosis; AGR; anterior gradient; AhR; aryl hydrocarbon receptor; AR; androgen receptor; CAPN8; calpain 8; CAPN9; calpain 9; CDDP; cisplatin; CFTR; cystic fibrosis transme

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Novel mutations and polymorphisms in the CFTR gene associated with three subtypes of congenital absence of vas deferens

Keywords: Congenital absence of vas deferens; CFTR; mutation; variant;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Role of cystic fibrosis transmembrane conductance regulator-associated ligand (CAL) in regulating the trafficking and signaling of corticotropin-releasing factor receptor 1

Keywords: 5HT2AR; Serotonin 2A receptor; ACTH; Adrenocorticotropin hormone; ANOVA; Analysis of variance; CAL; CFTR-associated ligand; cAMP; Cyclic adenosine monophosphate; CFTR; Cystic Fibrosis Transmembrane Conductance Regulator; CNS; Central nervous system; CRF;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The Cholangiopathies

Keywords: ADPLD; autosomal dominant polycystic liver disease; ADPKD; autosomal dominant polycystic kidney disease; AIDS; acquired immunodeficiency syndrome; ARPKD; autosomal recessive polycystic kidney disease; cAMP; cyclic adenosine monophosphate; CF; cystic fibro

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Loss of cftr function leads to pancreatic destruction in larval zebrafish

Keywords: Cftr; Cystic fibrosis; Pancreas

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Involvement of the heterodimeric interface region of the nucleotide binding domain-2 (NBD2) in the CFTR quaternary structure and membrane stability

Keywords: CFTR; NBD2; Dimerization; Membrane stability; Quaternary structure; Cystic fibrosis;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Variants in Solute Carrier SLC26A9 Modify Prenatal Exocrine Pancreatic Damage in Cystic Fibrosis

Keywords: 660W; Illumina 660W-Quad BeadChip; CF; Cystic fibrosis; CFTR; Cystic fibrosis transmembrane conductance regulator; IRT; Immunoreactive trypsinogen; NBS; Newborn screening/screened; Omni5; Illumina Omni5-Quad BeadChip; QC; Quality control; SNP; Single nucl

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

ReviewNew paradigms in the treatment of hepatic cholestasis: From UDCA to FXR, PXR and beyond

Keywords: AE2; anion exchanger 2; ASBT; apical sodium bile salt transporter; BA; bile acid; CA; cholic acid; CDCA; chenodeoxycholic acid; CFALD; cystic fibrosis-associated liver disease; CFTR; cystic fibrosis transmembrane conductance regulator; DCA; deoxycholic ac

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Comprehensive proteome quantification reveals NgBR as a new regulator for epithelial-mesenchymal transition of breast tumor cells

Keywords: NgBR; Nogo-B receptor; EMT; epithelial-mesenchymal transition; PI3K; phosphatidylinositol 3-kinase; GSK-3β; glycogen synthase kinase-3β; CNS; central nervous system; EC; endothelial cells; AmNogo-B; amino-terminal domain of Nogo-B; PS-DVB; polystyrene

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing

Keywords: AAD; active adenylation domain; 4-PBA; 4-phenylbutyric acid; 6-OHDA; 6-hydroxydopamine; ABCG5/8; ATP-binding cassette sub-family G member 5/8; AD; Alzheimer's disease; AIB1; amplified in breast cancer 1; AIP4; atrophin-1 interacting protein 4; AMPA; α-

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2015 سفارش ترجمه