Chemoprotection by sulforaphane: Keep one eye beyond Keap1
Keywords: پیشگیری شیمیایی; Sulforaphane; Chemoprevention
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Tinospora cordifolia induces enzymes of carcinogen/drug metabolism and antioxidant system, and inhibits lipid peroxidation in mice
Keywords: پیشگیری شیمیایی; Tinospora; Chemoprevention; Carcinogen/drug metabolizing enzymes; Antioxidant enzymes and lipid peroxidation
Chemoprevention of pancreatic cancer: A review of the molecular pathways involved, and evidence for the potential for chemoprevention
Keywords: پیشگیری شیمیایی; Pancreatic cancer; Chemoprevention; NSAIDS; COX-2; Polyphenols;
Chemoprevention of cervical cancer
Keywords: پیشگیری شیمیایی; antiviral agents; biomarkers; cervical cancer; chemoprevention; CIN; clinical trials; diindolylmethane; DIM; HPV; human papillomavirus; immune modifiers; micronutrients; secondary prevention
Inhibition of human cytochrome CYP1 enzymes by flavonoids of St. John's wort
Keywords: پیشگیری شیمیایی; EROD, ethoxyresorufin-O-deethylase; BaP, benzo(a)pyrene; TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxinCYP1A1; CYP1B1; Chemoprevention; prostate
In vitro cytotoxicity of a theaflavin mixture from black tea to malignant, immortalized, and normal cells from the human oral cavity
Keywords: پیشگیری شیمیایی; Theaflavin; Black tea; Oxidative stress; Chemoprevention; Polyphenol;
Cyclooxygenase-2 as a target for anticancer drug development
Keywords: پیشگیری شیمیایی; Cyclooxygenase; Cancer; Chemoprevention; Targeted therapy; Inflammation
The role of phytochemicals in inhibition of cancer and inflammation: New directions and perspectives
Keywords: پیشگیری شیمیایی; Antioxidants; Cell signaling pathways; Chemoprevention; COX-2; Dietary supplements; Herbs; Inflammation; iNOS; Phase II enzymes; Phytochemicals
Mediators of PGE2 synthesis and signalling downstream of COX-2 represent potential targets for the prevention/treatment of colorectal cancer
Keywords: پیشگیری شیمیایی; COX, cyclo-oxygenase; NSAID, non steroidal anti-inflammatory drug; PG, prostaglandin; EP, E-prostanoid; Tx, thromboxane; FAP, familial adenomatous polyposis; HNPCC, hereditary non-polyposis colorectal cancerCOX-2; NSAID; Chemoprevention; Colon cancer; EP
The effect of lifestyle factors on gynaecological cancer
Keywords: پیشگیری شیمیایی; chemoprevention; diet; hormones; human papillomavirus infection; lifestyle factors; obesity; prevention; risk factors
Efficacy of Deguelin and Silibinin on Benzo(a)pyrene-Induced Lung Tumorigenesis in A/J Mice
Keywords: پیشگیری شیمیایی; Chemoprevention; deguelin; silibinin; lung cancer; A/J mice;
Bladder cancer clinical trials
Keywords: پیشگیری شیمیایی; Bladder cancer; Clinical trials; Chemoprevention; Intravesical therapy; Chemotherapy; Immunotherapy;
Validation of chemoprevention of canine monocytic ehrlichiosis with doxycycline
Keywords: پیشگیری شیمیایی; Canine monocytic ehrlichiosis; Ehrlichia canis; Dogs; Doxycycline; Chemoprevention;
The role of stem cells and gap junctions as targets for cancer chemoprevention and chemotherapy
Keywords: پیشگیری شیمیایی; Human stem cells; Gap junctional communication; Chemoprevention;
Evidence for the preventive effect of the polyunsaturated phytol side chain in tocotrienols on 17β-estradiol epoxidation
Keywords: پیشگیری شیمیایی; α-Tocopherol; α-Tocotrienol; 17β-Estradiol epoxide; Chemoprevention; Breast cancer; Nuclear RNA synthesis; Dimethyldioxirane (DMDO); Rat liver nuclei; Liver microsomes; Vitamin E; Cancer prevention; Unsaturated fatty acid; Nuclear RNA synthesis; Dimeth
Cervical chromosome 9 polysomy: Validation and use as a surrogate endpoint biomarker in a 4-HPR chemoprevention trial
Keywords: پیشگیری شیمیایی; Cervix; Randomized clinical trials; Chemoprevention; Surrogate end point biomarkers; Chromosome 9 polysomy;
THE EFFECTS OF 5α-REDUCTASE INHIBITORS ON THE NATURAL HISTORY, DETECTION AND GRADING OF PROSTATE CANCER: CURRENT STATE OF KNOWLEDGE
Keywords: پیشگیری شیمیایی; prostate; prostatic neoplasms; chemoprevention; cholestenone 5 alpha-reductase
Lack of significant modifying effect of arctiin on prostate carcinogenesis in probasin/SV40 T antigen transgenic rats
Keywords: پیشگیری شیمیایی; Chemoprevention; Endocrine disruptor compounds; Arctiin; Prostate cancer; SV 40 T antigen transgenic rat;
Inhibitory effects of Pfaffia paniculata (Brazilian ginseng) on preneoplastic and neoplastic lesions in a mouse hepatocarcinogenesis model
Keywords: پیشگیری شیمیایی; Hepatocarcinogenesis; Pfaffia paniculata; Liver; Cancer; Chemoprevention; DEN; diethylnitrosamine; H and E; hematoxilin and eosin;
Inhibitory effect of etodolac, a selective cyclooxygenase-2 inhibitor, on stomach carcinogenesis in Helicobacter pylori-infected Mongolian gerbils
Keywords: پیشگیری شیمیایی; Stomach cancer; COX-2; Helicobacter pylori; Mongolian gerbils; Chemoprevention; Etodolac; Carcinogenesis;
Prostatic Intraepithelial Neoplasia (PIN): Importance and Clinical Management
Keywords: پیشگیری شیمیایی; Prostate cancer; High grade prostatic intraepithelial neoplasia (HG PIN); Low grade prostatic intraepithelial neoplasia (LG PIN); Chemoprevention;
Feasibility of performing chemoprevention trials in women at elevated risk of ovarian carcinoma: Initial examination of celecoxib as a chemopreventive agent
Keywords: پیشگیری شیمیایی; Ovarian cancer; Chemoprevention; NSAIDs;
Protection against aflatoxin-B1-induced liver mutagenesis by Scutellaria baicalensis
Keywords: پیشگیری شیمیایی; Mutagenicity; Plants; Scutellaria; Chemoprevention; Transgenic; lacI;
Development of cancer chemopreventive drugs based on mechanistic approaches
Keywords: پیشگیری شیمیایی; Chemoprevention; Drug development; Anticancer; Antimutagenesis; Chemoprotection;
The soy isoflavone daidzein improves the capacity of tamoxifen to prevent mammary tumours
Keywords: پیشگیری شیمیایی; Breast cancer; Chemoprevention; Daidzein; DNA damage; DMBA; Equol; Genistein; Isoflavones; Soy; Tamoxifen;
Resistance of prostate cancer cell lines to COX-2 inhibitor treatment
Keywords: پیشگیری شیمیایی; Prostate cancer; LNCaP; COX-2; Chemoprevention; Prostaglandin E2; Apoptosis;
Comparative evaluation of the chemopreventive efficacy of green and black tea polyphenols in the hamster buccal pouch carcinogenesis model
Keywords: پیشگیری شیمیایی; Chemoprevention; Hamster buccal pouch carcinogenesis; Polyphenon-E; Polyphenon-B;
Chemopreventive activities of Trigonella foenum graecum (Fenugreek) against breast cancer
Keywords: پیشگیری شیمیایی; Breast cancer; Fenugreek; Chemoprevention; Rat; DMBA; 7,12-dimethylbenz(α)anthracene; PAHs; polycyclic aromatic hydrocarbons; PR; progesterone receptor; E-cad; E-cadherine; ABC; avidin-biotin complex;
Celecoxib, a cyclooxygenase-2 inhibitor, prevents induction of liver preneoplastic lesions in rats
Keywords: پیشگیری شیمیایی; Selective cyclooxygenase-2 inhibitor; Chemoprevention; Hepatocarcinogenesis; 2-AAF; 2-acetylaminofluorene; COX; cyclooxygenase; DEN; diethylnitrosamine; GGT; γ-glutamyltranspeptidase; GST-P; glutathione S-transferase placental form; HPT; hepatocarcinogen
Congulated linoleic acid decreases cellular proliferation and inhibits nuclear factor-κB and activator protein 1 activation in PC3 cancerous prostate epithelial cells
Keywords: پیشگیری شیمیایی; Conjugated linoleic acid; Chemoprevention; Prostate cancer; Nuclear factor-κB; Activator protein 1; Peroxisome proliferator-activated receptor;
The role of folates in squamous cell carcinoma of the head and neck
Keywords: پیشگیری شیمیایی; Folate; Head and neck cancer; Squamous cell carcinoma; Chemoprevention;
The nonsteroidal anti-inflammatory drug, nabumetone, differentially inhibits β-catenin signaling in the MIN mouse and azoxymethane-treated rat models of colon carcinogenesis
Keywords: پیشگیری شیمیایی; Colon cancer; Chemoprevention; Nonsteroidal anti-inflammatory drugs;
DNA damage and aberrant crypt foci as putative biomarkers to evaluate the chemopreventive effect of annatto (Bixa orellana L.) in rat colon carcinogenesis
Keywords: پیشگیری شیمیایی; Aberrant crypt foci; Annatto; Chemoprevention; Comet assay dimethylhidrazine; AC; aberrant crypt; ACF; aberrant crypt foci; DMH; 1,2 dimethylhydrazine;
Novel antimutagenic factors derived from the edible mushroom Agrocybe cylindracea
Keywords: پیشگیری شیمیایی; 2-AAF; 2-acetylaminofluorene; AFB1; aflatoxin B1; DMBA; 7,12-dimethylbenzo[a]anthracene; MeIQx; 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline; IQ; 3-amino-3-methylimidazo[4,5-f]quinoline; MMC; mitomycin C; MNU; N-methyl-N-nitrosourea; NDMA; N-nitrosodimet
Chemoprevention: From research to clinical oncology
Keywords: پیشگیری شیمیایی; Chemoprevention; Clinical trials; Breast neoplasm; Colorectal neoplasm; Prostate neoplasm
Chemopreventive properties of the ethanol extract of chinese licorice (Glycyrrhiza uralensis) root: induction of apoptosis and G1 cell cycle arrest in MCF-7 human breast cancer cells
Keywords: پیشگیری شیمیایی; Breast cancer; Chinese licorice root; Glycyrrhiza uralensis; Apoptosis; Chemoprevention; Cell cycle arrest;
Balsamodendron mukul suppresses benzoyl peroxide and ultraviolet light induced tumor promotional events in Swiss mice
Keywords: پیشگیری شیمیایی; B. mukul; Chemoprevention; Tumor promotion; Benzoyl peroxide; Ultraviolet light;
Diallyl sulfide inhibits diethylstilbesterol-induced DNA adducts in the breast of female ACI rats
Keywords: پیشگیری شیمیایی; DES, diethylstilbesterol; DAS, diallyl sulfide; dAP, deoxyadenosine monophosphate; dGMP, deoxyguanosine monophosphate; RALs, relative adduct levels; mtDNA, mitochondrial DNA; nDNA, nuclear DNA; NP1, nuclease P1; PEI, polyetheleneimine; PhIP, 2-amino-1-met
Broccoli and watercress suppress matrix metalloproteinase-9 activity and invasiveness of human MDA-MB-231 breast cancer cells
Keywords: پیشگیری شیمیایی; Cruciferous vegetables; Isothiocyanate; Matrix metalloproteinase; Invasion; Chemoprevention;
Chemoprevention of aflatoxicosis in poultry by dietary butylated hydroxytoluene
Keywords: پیشگیری شیمیایی; AFB1; aflatoxin B1; AFBO; exo-aflatoxin B1-8,9-epoxide; BHA; butylated hydroxyanisole; BHT; butylated hydroxytoluene; BSA; bovine serum albumin; CDNB; 1-chloro-2,4-dinitrophenol; CYPs; cytochrome P450s; DCNB; 3,4-dichloronitrobenzene; DMSO; dimethylsulfox
Oxidative stress and cyclooxygenase activity in prostate carcinogenesis: targets for chemopreventive strategies
Keywords: پیشگیری شیمیایی; Chemoprevention; Prostaglandin; Androgens; DNA adducts;
Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor
Keywords: پیشگیری شیمیایی; Mediterranean diet; Actin; Matrigel; Polyphenol; Elenolic acid; Hydroxytyrosol; Chemotherapy; Oncology; Cancer; Chemoprevention;
Cyclooxygenase-2: How good is it as a target for cancer chemoprevention?
Keywords: پیشگیری شیمیایی; Cancer; Chemoprevention; Coxib; Cyclooxygenase; Non-steroidal anti-inflammatory drugs; Prostaglandins
Chemoprevention of prostate cancer
Keywords: پیشگیری شیمیایی; Prostate cancer; Chemoprevention; Finasteride; Dutasteride; Selenium; Vitamin E; Vitamin D; COX-2; Soy; Lycopene; Green tea; Selective estrogen receptor modulators; Prostate Cancer Prevention Trial; Selenium and Vitamin E Cancer Prevention Trial;
Retinoids as chemoprevention for head and neck cancer: where do we go from here?
Keywords: پیشگیری شیمیایی; Retinoids; Chemoprevention; Head and neck cancer; Multi-step carcinogenesis; Field cancerization; Premalignant; Leukoplakia; 9-cis retinoic acid (9cRA); 13-cis retinoic acid (13cRA); Isotretinoin; Fenretinide; Etretinate; Biochemoprevention; CD437; Hetero
Inhibition of tumour promotion in mouse skin by extracts of rooibos (Aspalathus linearis) and honeybush (Cyclopia intermedia), unique South African herbal teas
Keywords: پیشگیری شیمیایی; Rooibos; Honeybush; TPA; Chemoprevention;
Antitumor, hematostimulative and radioprotective action of water-soluble derivative of propolis (WSDP)
Keywords: پیشگیری شیمیایی; Antimetastatic effect; Chemoprevention; Colony forming units (CFUs); Hematopoiesis; Mice; Propolis; Radioprotection;
Inhibitory effect of celery seeds extract on chemically induced hepatocarcinogenesis: modulation of cell proliferation, metabolism and altered hepatic foci development
Keywords: پیشگیری شیمیایی; A. graveolens; Hepatocarcinoma; Chemoprevention;
Anthocyans from fruits and vegetables – Does bright colour signal cancer chemopreventive activity?
Keywords: پیشگیری شیمیایی; Chemoprevention; Flavonoids; Anthocyanins; Anthocyanidins
EGFR blockade by cetuximab alone or as combination therapy for growth control of hepatocellular cancer
Keywords: پیشگیری شیمیایی; AG1024; 3-bromo-5-t-butyl-4-hydroxy-benzylidenemalonitrile; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; erlotinib; (N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine); HCC; hepatocellular carcinoma; HMG-CoA-reductase